COPB1

This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

Description

COPI coat complex subunit beta 1

Tissue specificity

Low tissue specificity

Subcell location

Golgi apparatus, Vesicles, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

11 (14443440 - 14500027)

Ensembl ID

ENSG00000129083  (ver. 103.38)

Orthologs

Mouse Copb1: ENSMUSG00000030754

UniProt

P53618

neXtProt

NX_P53618

Human splice variants
Mouse splice variants

Protein structure