Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA057002 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA057002, RRID:AB_2683308
- Product name
- Anti-AKR1D1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human AKR1D1, Gene description: aldo-keto reductase family 1, member D1, Alternative Gene Names: SRD5B1, Validated applications: IHC, WB, Uniprot ID: P51857, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.05 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Differential activity and expression of human 5β-reductase (AKR1D1) splice variants
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease
Appanna N, Gibson H, Gangitano E, Dempster N, Morris K, George S, Arvaniti A, Gathercole L, Keevil B, Penning T, Storbeck K, Tomlinson J, Nikolaou N
Journal of Molecular Endocrinology 2021;66(3):181-194
Journal of Molecular Endocrinology 2021;66(3):181-194
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo
Nikolaou N, Arvaniti A, Appanna N, Sharp A, Hughes B, Digweed D, Whitaker M, Ross R, Arlt W, Penning T, Morris K, George S, Keevil B, Hodson L, Gathercole L, Tomlinson J
Journal of Endocrinology 2020;245(2):207-218
Journal of Endocrinology 2020;245(2):207-218
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease
Nikolaou N, Gathercole L, Marchand L, Althari S, Dempster N, Green C, van de Bunt M, McNeil C, Arvaniti A, Hughes B, Sgromo B, Gillies R, Marschall H, Penning T, Ryan J, Arlt W, Hodson L, Tomlinson J
Metabolism 2019;99
Metabolism 2019;99
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and kidney tissues using HPA057002 antibody. Corresponding AKR1D1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
