OTX1

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Description

orthodenticle homeobox 1

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transcription factors

Chromosome

2:p15 (63050057 - 63057836)

Ensembl ID

ENSG00000115507  (ver. 99.38)

Orthologs

Mouse Otx1: ENSMUSG00000005917

UniProt

P32242

neXtProt

NX_P32242

Human splice variants
Mouse splice variants