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- Antibody Data
- Antigen structure
- References [14]
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- Immunohistochemistry [1]
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- Product number
- 11052-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11052-1-AP, RRID:AB_2226430
- Product name
- AMD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AMD1 antibody (Cat. #11052-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references AMD1 promotes breast cancer aggressiveness via a spermidine-eIF5A hypusination-TCF4 axis.
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Angiocrine polyamine production regulates adiposity.
Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism.
The KRAS-G12D mutation induces metabolic vulnerability in B-cell acute lymphoblastic leukemia.
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes.
Polyamine synthesis enzyme AMD1 is closely related to the tumorigenesis and prognosis of human breast cancer.
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.
Polyamine pathway activity promotes cysteine essentiality in cancer cells.
Polyamine synthesis enzyme AMD1 is closely associated with tumorigenesis and prognosis of human gastric cancers.
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Liao R, Chen X, Cao Q, Bai L, Ma C, Dai Z, Dong C
Breast cancer research : BCR 2024 Apr 23;26(1):70
Breast cancer research : BCR 2024 Apr 23;26(1):70
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
Uemura T, Matsunaga M, Yokota Y, Takao K, Furuchi T
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Halloran KM, Stenhouse C, Moses RM, Seo H, Johnson GA, Wu G, Bazer FW
Biology of reproduction 2022 May 17;106(5):865-878
Biology of reproduction 2022 May 17;106(5):865-878
Angiocrine polyamine production regulates adiposity.
Monelli E, Villacampa P, Zabala-Letona A, Martinez-Romero A, Llena J, Beiroa D, Gouveia L, Chivite I, Zagmutt S, Gama-Perez P, Osorio-Conles O, Muixi L, Martinez-Gonzalez A, Castillo SD, Martín-Martín N, Castel P, Valcarcel-Jimenez L, Garcia-Gonzalez I, Villena JA, Fernandez-Ruiz S, Serra D, Herrero L, Benedito R, Garcia-Roves P, Vidal J, Cohen P, Nogueiras R, Claret M, Carracedo A, Graupera M
Nature metabolism 2022 Mar;4(3):327-343
Nature metabolism 2022 Mar;4(3):327-343
Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism.
Dörner K, Badertscher L, Horváth B, Hollandi R, Molnár C, Fuhrer T, Meier R, Sárazová M, van den Heuvel J, Zamboni N, Horvath P, Kutay U
Nucleic acids research 2022 Mar 21;50(5):2872-2888
Nucleic acids research 2022 Mar 21;50(5):2872-2888
The KRAS-G12D mutation induces metabolic vulnerability in B-cell acute lymphoblastic leukemia.
Xu Y, Fang H, Chen Y, Tang Y, Sun H, Kong Z, Yang F, Kirschner-Schwabe R, Zhu L, Toker A, Xiao N, Zhou BS, Li H
iScience 2022 Mar 18;25(3):103881
iScience 2022 Mar 18;25(3):103881
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes.
Shu S, Kobayashi M, Marunaka K, Yoshino Y, Goto M, Katsuta Y, Ikari A
Cells 2022 Jul 22;11(15)
Cells 2022 Jul 22;11(15)
Polyamine synthesis enzyme AMD1 is closely related to the tumorigenesis and prognosis of human breast cancer.
Gao H, Li H, Wang J, Xu C, Zhu Y, Tuluhong D, Li X, Wang S, Li J
Experimental cell research 2022 Aug 15;417(2):113235
Experimental cell research 2022 Aug 15;417(2):113235
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM
iScience 2022 Apr 15;25(4):104162
iScience 2022 Apr 15;25(4):104162
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W
Clinical and translational medicine 2021 Mar;11(3):e352
Clinical and translational medicine 2021 Mar;11(3):e352
Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.
Uemura T, Akasaka Y, Ikegaya H
Heliyon 2020 Sep;6(9):e05031
Heliyon 2020 Sep;6(9):e05031
Polyamine pathway activity promotes cysteine essentiality in cancer cells.
Zhang T, Bauer C, Newman AC, Uribe AH, Athineos D, Blyth K, Maddocks ODK
Nature metabolism 2020 Oct;2(10):1062-1076
Nature metabolism 2020 Oct;2(10):1062-1076
Polyamine synthesis enzyme AMD1 is closely associated with tumorigenesis and prognosis of human gastric cancers.
Xu L, You X, Cao Q, Huang M, Hong LL, Chen XL, Lei L, Ling ZQ, Chen Y
Carcinogenesis 2020 Apr 22;41(2):214-222
Carcinogenesis 2020 Apr 22;41(2):214-222
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Zabala-Letona A, Arruabarrena-Aristorena A, Martín-Martín N, Fernandez-Ruiz S, Sutherland JD, Clasquin M, Tomas-Cortazar J, Jimenez J, Torres I, Quang P, Ximenez-Embun P, Bago R, Ugalde-Olano A, Loizaga-Iriarte A, Lacasa-Viscasillas I, Unda M, Torrano V, Cabrera D, van Liempd SM, Cendon Y, Castro E, Murray S, Revandkar A, Alimonti A, Zhang Y, Barnett A, Lein G, Pirman D, Cortazar AR, Arreal L, Prudkin L, Astobiza I, Valcarcel-Jimenez L, Zuñiga-García P, Fernandez-Dominguez I, Piva M, Caro-Maldonado A, Sánchez-Mosquera P, Castillo-Martín M, Serra V, Beraza N, Gentilella A, Thomas G, Azkargorta M, Elortza F, Farràs R, Olmos D, Efeyan A, Anguita J, Muñoz J, Falcón-Pérez JM, Barrio R, Macarulla T, Mato JM, Martinez-Chantar ML, Cordon-Cardo C, Aransay AM, Marks K, Baselga J, Tabernero J, Nuciforo P, Manning BD, Marjon K, Carracedo A
Nature 2017 Jul 6;547(7661):109-113
Nature 2017 Jul 6;547(7661):109-113
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AMD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AMD1. This antibody recognizes human, mouse, rat antigen. The AMD1 antibody has been validated for the following applications: ELISA, IHC analysis.
