Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 14813-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14813-1-AP, RRID:AB_2279638
- Product name
- HNRNPA2B1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HNRNPA2B1 antibody (Cat. #14813-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Compensatory expression regulation of highly homologous proteins HNRNPA1 and HNRNPA2.
Analysis of m6A-Related Signatures in the Tumor Immune Microenvironment and Identification of Clinical Prognostic Regulators in Adrenocortical Carcinoma.
HNRNPA2B1, as a m6A Reader, Promotes Tumorigenesis and Metastasis of Oral Squamous Cell Carcinoma.
CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner.
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
METTL3 regulates heterochromatin in mouse embryonic stem cells.
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
m6A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.
Bioinformatics-Driven New Immune Target Discovery in Disease.
Nuclear TDP-43 causes neuronal toxicity by escaping from the inhibitory regulation by hnRNPs.
Targeting the cyclophilin domain of Ran-binding protein 2 (Ranbp2) with novel small molecules to control the proteostasis of STAT3, hnRNPA2B1 and M-opsin.
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.
HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells.
Chang Y, Lu X, Qiu J
Turkish journal of biology = Turk biyoloji dergisi 2021;45(2):187-195
Turkish journal of biology = Turk biyoloji dergisi 2021;45(2):187-195
Analysis of m6A-Related Signatures in the Tumor Immune Microenvironment and Identification of Clinical Prognostic Regulators in Adrenocortical Carcinoma.
Jin Y, Wang Z, He D, Zhu Y, Hu X, Gong L, Xiao M, Chen X, Cheng Y, Cao K
Frontiers in immunology 2021;12:637933
Frontiers in immunology 2021;12:637933
HNRNPA2B1, as a m6A Reader, Promotes Tumorigenesis and Metastasis of Oral Squamous Cell Carcinoma.
Zhu F, Yang T, Yao M, Shen T, Fang C
Frontiers in oncology 2021;11:716921
Frontiers in oncology 2021;11:716921
CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner.
Liu X, Liu Y, Liu Z, Lin C, Meng F, Xu L, Zhang X, Zhang C, Zhang P, Gong S, Wu N, Ren Z, Song J, Zhang Y
Molecular cancer 2021 Sep 8;20(1):114
Molecular cancer 2021 Sep 8;20(1):114
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Chen ZQ, Yuan T, Jiang H, Yang YY, Wang L, Fu RM, Luo SQ, Zhang T, Wu ZY, Wen KM
Oncology reports 2021 Oct;46(4)
Oncology reports 2021 Oct;46(4)
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
Li C, Qin F, Wang W, Ni Y, Gao M, Guo M, Sun G
International journal of molecular sciences 2021 Nov 28;22(23)
International journal of molecular sciences 2021 Nov 28;22(23)
METTL3 regulates heterochromatin in mouse embryonic stem cells.
Xu W, Li J, He C, Wen J, Ma H, Rong B, Diao J, Wang L, Wang J, Wu F, Tan L, Shi YG, Shi Y, Shen H
Nature 2021 Mar;591(7849):317-321
Nature 2021 Mar;591(7849):317-321
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Li WJ, He YH, Yang JJ, Hu GS, Lin YA, Ran T, Peng BL, Xie BL, Huang MF, Gao X, Huang HH, Zhu HH, Ye F, Liu W
Nature communications 2021 Mar 29;12(1):1946
Nature communications 2021 Mar 29;12(1):1946
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142
Nature structural & molecular biology 2021 Feb;28(2):132-142
m6A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1.
Guo H, Wang B, Xu K, Nie L, Fu Y, Wang Z, Wang Q, Wang S, Zou X
Frontiers in oncology 2020;10:553045
Frontiers in oncology 2020;10:553045
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
Chen Z, Chen X, Lei T, Gu Y, Gu J, Huang J, Lu B, Yuan L, Sun M, Wang Z
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1479-1493
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1479-1493
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
Zhang Y, Liu X, Liu L, Li J, Hu Q, Sun R
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644
The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.
He T, Jin M, Xu C, Ma Z, Wu F, Zhang X
Oncogene 2018 Oct;37(43):5766-5779
Oncogene 2018 Oct;37(43):5766-5779
Bioinformatics-Driven New Immune Target Discovery in Disease.
Yang C, Chen P, Zhang W, Du H
Scandinavian journal of immunology 2016 Aug;84(2):130-6
Scandinavian journal of immunology 2016 Aug;84(2):130-6
Nuclear TDP-43 causes neuronal toxicity by escaping from the inhibitory regulation by hnRNPs.
Suzuki H, Shibagaki Y, Hattori S, Matsuoka M
Human molecular genetics 2015 Mar 15;24(6):1513-27
Human molecular genetics 2015 Mar 15;24(6):1513-27
Targeting the cyclophilin domain of Ran-binding protein 2 (Ranbp2) with novel small molecules to control the proteostasis of STAT3, hnRNPA2B1 and M-opsin.
Cho KI, Orry A, Park SE, Ferreira PA
ACS chemical neuroscience 2015 Aug 19;6(8):1476-85
ACS chemical neuroscience 2015 Aug 19;6(8):1476-85
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.
Cho KI, Patil H, Senda E, Wang J, Yi H, Qiu S, Yoon D, Yu M, Orry A, Peachey NS, Ferreira PA
The Journal of biological chemistry 2014 Feb 21;289(8):4600-25
The Journal of biological chemistry 2014 Feb 21;289(8):4600-25
HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells.
Guo R, Li Y, Ning J, Sun D, Lin L, Liu X
PloS one 2013;8(4):e62729
PloS one 2013;8(4):e62729
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 14813-1-AP(HNRNPA2B1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HNRNPA2B1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HNRNPA2B1. This antibody recognizes human,mouse,rat antigen. The HNRNPA2B1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.