PA1767
antibody from Boster Biological Technology
Targeting: KLK6
Bssp, Klk7, neurosin, PRSS18, PRSS9
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PA1767 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Kallikrein 6/KLK6 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for Kallikrein 6/KLK6 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Kallikrein 6/KLK6 information: Molecular Weight: 26856 MW; Subcellular Localization: Secreted. Nucleus, nucleolus. Cytoplasm. Mitochondrion. Microsome. In brain, detected in the nucleus of glial cells and in the nucleus and cytoplasm of neurons. Detected in the mitochondrial and microsomal fractions of HEK-293 cells and released into the cytoplasm following cell stress; Tissue Specificity: In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urine. At the tissue level, highest concentrations found in glandular tissues such as salivary glands followed by lung, colon, fallopian tube, placenta, breast, pituitary and kidney. Not detected in skin, spleen, bone, thyroid, heart, ureter, liver, muscle, endometrium, testis, pancreas, seminal vesicle, ovary, adrenals and prostate. In brain, detected in gray matter neurons (at protein level). Colocalizes with pathological inclusions such as Lewy bodies and glial cytoplasmic inclusions. Overexpressed in primary breast tumors but not expressed in metastatic tumors.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis.
Bouzid H, Soualmia F, Oikonomopoulou K, Soosaipillai A, Walker F, Louati K, Lo Dico R, Pocard M, El Amri C, Ignatenko NA, Darmoul D
Biomolecules 2022 Jul 19;12(7)
Biomolecules 2022 Jul 19;12(7)
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-Kallikrein 6 antibody, PA1767, Western blottingAll lanes: Anti Kallikrein 6 (PA1767) at 0.5ug/ml Lane 1: MCF-7 Whole Cell Lysate at 40ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: MM231 Whole Cell Lysate at 40ug Lane 4: MM453 Whole Cell Lysate at 40ug Lane 5: A549 Whole Cell Lysate at 40ug Lane 6: SMMC Whole Cell Lysate at 40ug Lane 7: COLO320 Whole Cell Lysate at 40ug Lane 8: SW620 Whole Cell Lysate at 40ug Lane 9: HT1080 Whole Cell Lysate at 40ug Predicted bind size: 27KD Observed bind size: 27KD
- Additional image