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- Antibody Data
- Antigen structure
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- Immunohistochemistry [1]
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- Product number
- AF2008 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Kallikrein 6/Neurosin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human Kallikrein 6 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Kallikrein 3, rhKallikrein 5, rhKallikrein 11, rhKallikrein 13, rhKallikrein 14, and rhKallikrein 15 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q92876- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Expression of Kallikrein-Related Peptidase 6 in Primary Mucosal Malignant Melanoma of the Head and Neck.
Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients.
Phenotypic characterization of hereditary epithelial ovarian cancer based on a tissue microarray study.
Novel expression of kallikreins, kallikrein-related peptidases and kinin receptors in human pleural mesothelioma.
Thierauf J, Veit JA, Lennerz JK, Weissinger SE, Affolter A, Döscher J, Bergmann C, Knopf A, Grünow J, Grünmüller L, Mauch C, Plinkert PK, Hoffmann TK, Hess J
Head and neck pathology 2017 Sep;11(3):314-320
Head and neck pathology 2017 Sep;11(3):314-320
Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients.
Schrader CH, Kolb M, Zaoui K, Flechtenmacher C, Grabe N, Weber KJ, Hielscher T, Plinkert PK, Hess J
Molecular cancer 2015 May 20;14:107
Molecular cancer 2015 May 20;14:107
Phenotypic characterization of hereditary epithelial ovarian cancer based on a tissue microarray study.
Muñoz-Repeto I, García MJ, Kamieniak M, Ramón Y Cajal T, Domingo S, Cazorla A, García Donas J, Hernando Polo S, García Sagredo JM, Hernández E, Lacambra C, Saez R, Robles L, Borrego S, Prat J, Palacios J, Benítez J
Histology and histopathology 2013 Jan;28(1):133-44
Histology and histopathology 2013 Jan;28(1):133-44
Novel expression of kallikreins, kallikrein-related peptidases and kinin receptors in human pleural mesothelioma.
Chee J, Singh J, Naran A, Misso NL, Thompson PJ, Bhoola KD
Biological chemistry 2007 Nov;388(11):1235-42
Biological chemistry 2007 Nov;388(11):1235-42
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Kallikrein 6/Neurosin in Human Breast Cancer Tissue. Kallikrein 6/Neurosin was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 15 µg/mL Goat Anti-Human Kallikrein 6/Neurosin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2008) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
