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- Antigen structure
- References [14]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15689-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15689-1-AP, RRID:AB_2197820
- Product name
- STARD7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STARD7 antibody (Cat. #15689-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Specific SLC25 carriers regulate mitochondrial protein synthesis.
Loss of STARD7 Impairs Mitochondrial Phospholipid Homeostasis and Contributes to Mitochondrial Myopathy.
Rewiring of 3D chromatin topology orchestrates transcriptional reprogramming in muscle fiber-type specification and transformation.
Leaflet specific phospholipid imaging using genetically encoded proximity sensors.
The ORP9-ORP11 dimer promotes sphingomyelin synthesis.
OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response.
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7.
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Intronic ATTTC repeat expansions in STARD7 in familial adult myoclonic epilepsy linked to chromosome 2.
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7.
PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Rudler DL, Hughes LA, King MS, Baker J, Lee RG, Gandadireja AP, Sunil A, Fagan SV, Payne B, Gray N, McCubbin T, Kunji ERS, Rackham O, Filipovska A
Science advances 2026 Feb 27;12(9):eaeb0049
Science advances 2026 Feb 27;12(9):eaeb0049
Loss of STARD7 Impairs Mitochondrial Phospholipid Homeostasis and Contributes to Mitochondrial Myopathy.
Horibata Y, Sato T, Ohyama M, Yuyama S, Itoh M, Miura S, Konishi A, Sugimoto H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71777
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71777
Rewiring of 3D chromatin topology orchestrates transcriptional reprogramming in muscle fiber-type specification and transformation.
Tan B, Hong L, Xiao L, Wu J, Lu G, Wang S, Liu L, Zheng E, Cai G, Li Z, Gu T, Wu Z
Nature communications 2025 Jul 1;16(1):5833
Nature communications 2025 Jul 1;16(1):5833
Leaflet specific phospholipid imaging using genetically encoded proximity sensors.
Moore WM, Brea RJ, Knittel CH, Wrightsman E, Hui B, Lou J, Ancajas CF, Best MD, Obara CJ, Devaraj NK, Budin I
bioRxiv : the preprint server for biology 2025 Aug 26;
bioRxiv : the preprint server for biology 2025 Aug 26;
The ORP9-ORP11 dimer promotes sphingomyelin synthesis.
Cabukusta B, Borst Pauwels S, Akkermans JJLL, Blomberg N, Mulder AA, Koning RI, Giera M, Neefjes J
eLife 2024 Aug 6;12
eLife 2024 Aug 6;12
OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response.
Liang FG, Zandkarimi F, Lee J, Axelrod JL, Pekson R, Yoon Y, Stockwell BR, Kitsis RN
Molecular cell 2024 Aug 22;84(16):3098-3114.e6
Molecular cell 2024 Aug 22;84(16):3098-3114.e6
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M
eLife 2023 Jul 28;12
eLife 2023 Jul 28;12
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7.
Deshwal S, Onishi M, Tatsuta T, Bartsch T, Cors E, Ried K, Lemke K, Nolte H, Giavalisco P, Langer T
Nature cell biology 2023 Feb;25(2):246-257
Nature cell biology 2023 Feb;25(2):246-257
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Purandare N, Kunji Y, Xi Y, Romero R, Gomez-Lopez N, Fribley A, Grossman LI, Aras S
iScience 2022 Nov 18;25(11):105342
iScience 2022 Nov 18;25(11):105342
Intronic ATTTC repeat expansions in STARD7 in familial adult myoclonic epilepsy linked to chromosome 2.
Corbett MA, Kroes T, Veneziano L, Bennett MF, Florian R, Schneider AL, Coppola A, Licchetta L, Franceschetti S, Suppa A, Wenger A, Mei D, Pendziwiat M, Kaya S, Delledonne M, Straussberg R, Xumerle L, Regan B, Crompton D, van Rootselaar AF, Correll A, Catford R, Bisulli F, Chakraborty S, Baldassari S, Tinuper P, Barton K, Carswell S, Smith M, Berardelli A, Carroll R, Gardner A, Friend KL, Blatt I, Iacomino M, Di Bonaventura C, Striano S, Buratti J, Keren B, Nava C, Forlani S, Rudolf G, Hirsch E, Leguern E, Labauge P, Balestrini S, Sander JW, Afawi Z, Helbig I, Ishiura H, Tsuji S, Sisodiya SM, Casari G, Sadleir LG, van Coller R, Tijssen MAJ, Klein KM, van den Maagdenberg AMJM, Zara F, Guerrini R, Berkovic SF, Pippucci T, Canafoglia L, Bahlo M, Striano P, Scheffer IE, Brancati F, Depienne C, Gecz J
Nature communications 2019 Oct 29;10(1):4920
Nature communications 2019 Oct 29;10(1):4920
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T
EMBO molecular medicine 2019 Jan;11(1)
EMBO molecular medicine 2019 Jan;11(1)
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7.
Bockelmann S, Mina JGM, Korneev S, Hassan DG, Müller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, Holthuis JCM
Journal of lipid research 2018 Mar;59(3):515-530
Journal of lipid research 2018 Mar;59(3):515-530
PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
Saita S, Tatsuta T, Lampe PA, König T, Ohba Y, Langer T
The EMBO journal 2018 Feb 15;37(4)
The EMBO journal 2018 Feb 15;37(4)
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T
Nature cell biology 2017 Apr;19(4):318-328
Nature cell biology 2017 Apr;19(4):318-328
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15689-1-AP(STARD7 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15689-1-AP(STARD7 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STARD7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STARD7. This antibody recognizes human, mouse, rat antigen. The STARD7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
