CABT-BL153

antibody from Creative Diagnostics

Targeting: AANAT SNAT

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL153

Provider

Creative Diagnostics

Product name

Anti-AANAT polyclonal antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternative splicing results in multiple transcript variants.

Reactivity

Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.