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- Antibody Data
- Antigen structure
- References [17]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 13755-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13755-1-AP, RRID:AB_2262872
- Product name
- FMR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FMR1 antibody (Cat. #13755-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A new mechanism regulating microglial NLRP3 inflammasome: FMR1 mediates NLRP3 mRNA stability.
METTL3-mediated m6A modification of FDX1 confers resistance to cuproptosis and promotes hepatocellular carcinoma progression.
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
FDX1 overexpression inhibits the growth and metastasis of clear cell renal cell carcinoma by upregulating FMR1 expression.
ERβ/circAHNAK Axis Inhibits USP10-FMR1 Deubiquitination to Prevent m⁶A-Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma.
Atrazine exposure induces TDP-43 protein translocation: A potential mechanism for prefrontal cortical neurodegeneration induced by environmental pollutants.
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer.
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
MNSFβ promotes LPS-induced TNFα expression by increasing the localization of RC3H1 to stress granules, and the interfering peptide HEPN2 reduces TNFα production by disrupting the MNSFβ-RC3H1 interaction in macrophages.
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Decreased DANCR contributes to high glucose-induced extracellular matrix accumulation in human renal mesangial cell via regulating the TGF-β/Smad signaling.
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
FMR1 promotes the progression of colorectal cancer cell by stabilizing EGFR mRNA in an m(6)A-dependent manner.
MiR-323a-3p acts as a tumor suppressor by suppressing FMR1 and predicts better esophageal squamous cell carcinoma outcome.
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
Deng Q, Bai Q, Yang Y, Tang W, Liu F, Zhang S, Wang H, Xing Z, Zhang C, Yang Y, Fu Q, Fan H
PloS one 2026;21(2):e0341867
PloS one 2026;21(2):e0341867
METTL3-mediated m6A modification of FDX1 confers resistance to cuproptosis and promotes hepatocellular carcinoma progression.
Jiang Q, Peng C, Mao W, Yu Z, Feng Y, Li Y, Zhu J, Zhao J, Liao D, Sun T
Communications biology 2026 Jan 8;9(1):222
Communications biology 2026 Jan 8;9(1):222
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
Yin L, Zhang Y, Zhang B, Zhang J, Xiong M, Jiang N, Xiao J, Gao H, Xiong W, Wang X, Wang F, Yuan S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
FDX1 overexpression inhibits the growth and metastasis of clear cell renal cell carcinoma by upregulating FMR1 expression.
Yang W, Wu C, Jiang C, Jing T, Lu M, Xia D, Peng D
Cell death discovery 2025 Mar 21;11(1):115
Cell death discovery 2025 Mar 21;11(1):115
ERβ/circAHNAK Axis Inhibits USP10-FMR1 Deubiquitination to Prevent m⁶A-Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma.
Xu C, Zhang S, Liu Y, Lv J, Cao Y, Chen Y, Sun H, Zhang B, Dai S, Li J, Li X, Shi B, Sun Q, Zhu M, Gu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e09654
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e09654
Atrazine exposure induces TDP-43 protein translocation: A potential mechanism for prefrontal cortical neurodegeneration induced by environmental pollutants.
Ma Y, Wang K, Jiao Y, Li Y, Hu R, Li Y, Shi G, Huang M
Toxicology 2025 Aug;515:154128
Toxicology 2025 Aug;515:154128
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer.
Li Y, Xu C, Qian X, Wang G, Han C, Hua H, Dong M, Chen J, Yu H, Zhang R, Feng X, Yang Z, Pan Y
Cell death discovery 2024 Jul 30;10(1):344
Cell death discovery 2024 Jul 30;10(1):344
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
Wang X, Fan X, Zhang J, Wang F, Chen J, Wen Y, Wang L, Li T, Li H, Gu H, Zhang Y, Yuan S
Cell reports 2024 Feb 27;43(2):113769
Cell reports 2024 Feb 27;43(2):113769
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B
Nature communications 2024 Feb 22;15(1):1637
Nature communications 2024 Feb 22;15(1):1637
MNSFβ promotes LPS-induced TNFα expression by increasing the localization of RC3H1 to stress granules, and the interfering peptide HEPN2 reduces TNFα production by disrupting the MNSFβ-RC3H1 interaction in macrophages.
Jiang HY, Gu WW, Gan J, Yang Q, Shi Y, Lian WB, Xu HR, Yang SH, Yang L, Zhang X, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):113053
International immunopharmacology 2024 Dec 5;142(Pt A):113053
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Zhong C, Long Z, Yang T, Wang S, Zhong W, Hu F, Teoh JY, Lu J, Mao X
International journal of biological sciences 2023;19(5):1543-1563
International journal of biological sciences 2023;19(5):1543-1563
Decreased DANCR contributes to high glucose-induced extracellular matrix accumulation in human renal mesangial cell via regulating the TGF-β/Smad signaling.
Liu F, Cao Y, Zhang C, Su H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22926
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22926
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
FMR1 promotes the progression of colorectal cancer cell by stabilizing EGFR mRNA in an m(6)A-dependent manner.
Hu Y, Gao Q, Ma S, Yu P, Ding S, Yao X, Zhang Z, Lu S, Lu M, Zhang J, Wang Y, Qian X, Zhong J
Cell death & disease 2022 Nov 8;13(11):941
Cell death & disease 2022 Nov 8;13(11):941
MiR-323a-3p acts as a tumor suppressor by suppressing FMR1 and predicts better esophageal squamous cell carcinoma outcome.
Men Y, Zhai Y, Wu L, Liu L, Zhang W, Jiang W, Bi N, Song Y, Hui Z, Wang L
Cancer cell international 2022 Mar 29;22(1):140
Cancer cell international 2022 Mar 29;22(1):140
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E
Biology 2022 Feb 11;11(2)
Biology 2022 Feb 11;11(2)
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
Sanders DW, Kedersha N, Lee DSW, Strom AR, Drake V, Riback JA, Bracha D, Eeftens JM, Iwanicki A, Wang A, Wei MT, Whitney G, Lyons SM, Anderson P, Jacobs WM, Ivanov P, Brangwynne CP
Cell 2020 Apr 16;181(2):306-324.e28
Cell 2020 Apr 16;181(2):306-324.e28
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 13755-1-AP(FMR1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells using 13755-1-AP( FMR1 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-FMR1(13755-1-AP for IP and Detection).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 13755-1-AP(FMR1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
