BS8370
antibody from Bioworld Technology, Inc
Targeting: PRPF19
hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS8370 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PRPF19 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PRPF19.
- Description
- The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5£ª splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of PRPF19 polyclonal antibody