HPA027578

antibody from Atlas Antibodies

Targeting: RNF220 C1orf164, FLJ10597

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA027578

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA027578, RRID:AB_10601482

Product name

Anti-RNF220

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human RNF220, Gene description: ring finger protein 220, Alternative Gene Names: C1orf164, FLJ10597, Validated applications: IHC, Uniprot ID: Q5VTB9, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

Liu X, Wang H, Liu Y, Yang C, Ye Y, Yu X, Sheng N, Zhang S, Mao B, Ma P
eLife 2024;13

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RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination

Li Y, Wan L, Song N, Ding Y, Zhao S, Niu J, Mao B, Sheng N, Ma P
Science Advances 2024;10(6)

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Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma

Li Y, Wang H, Sun B, Su G, Cang Y, Zhao L, Zhao S, Li Y, Mao B, Ma P
Cell Death & Disease 2023;14(8)

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RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission

Ma P, Wan L, Li Y, He C, Song N, Zhao S, Wang H, Ding Y, Mao B, Sheng N
Science Advances 2022;8(39)

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Praja1 RING-finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease-associated protein aggregation.

Watabe K, Niida-Kawaguchi M, Tada M, Kato Y, Murata M, Tanji K, Wakabayashi K, Yamada M, Kakita A, Shibata N
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Dec;42(6):488-504

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Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse

Ma P, Li Y, Wang H, Mao B, Luo Z
Journal of Molecular Cell Biology 2021;13(5):374-382

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Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation

Zhang L, Ye M, Zhu L, Cha J, Li C, Yao Y, Mao B
Cells 2020;9(7):1600

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RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense

Guo X, Ma P, Li Y, Yang Y, Wang C, Xu T, Wang H, Li C, Mao B, Qi X
Cell Death & Differentiation 2020;28(2):640-656