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- References [10]
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- Product number
- 11487-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11487-1-AP, RRID:AB_2117517
- Product name
- HECTD3 antibody
- Antibody type
- Polyclonal
- Description
- HECTD3 antibody (Cat. #11487-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HTATSF1 regulates innate antiviral immune response by orchestrating TRAF3-IRF3 and TRAF6-NF-κB pathways.
Exosome-derived lnc-FAM72D-3 promotes lenvatinib resistance by remodeling hepatocellular carcinoma cytoskeleton via MBNL1/FAK axis.
Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning.
USP25 Elevates SHLD2-Mediated DNA Double-Strand Break Repair and Regulates Chemoresponse in Cancer.
HECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
uc.77- Downregulation Promotes Colorectal Cancer Cell Proliferation by Inhibiting FBXW8-Mediated CDK4 Protein Degradation.
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Zeng JQ, Ruan ZL, Zhang Q, Yi XM, Chen YD, Hu MM, Li S
Cell insight 2026 Feb;5(1):100294
Cell insight 2026 Feb;5(1):100294
Exosome-derived lnc-FAM72D-3 promotes lenvatinib resistance by remodeling hepatocellular carcinoma cytoskeleton via MBNL1/FAK axis.
Cao M, Li Y, Su X, Tang Y, Ren Y, Luo J, Yuan F, Yang G, He Z, Shi Z, Hu Z, Liang G, Zhang Q, Deng M, Yao Z, Lin N
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101271
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101271
Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning.
Yuan Y, Jiang H, Xue R, Feng XJ, Liu BF, Li L, Peng B, Ren CS, Li SM, Li N, Li M, Wang DB, Zhang XE
Journal of extracellular vesicles 2025 May;14(5):e70078
Journal of extracellular vesicles 2025 May;14(5):e70078
USP25 Elevates SHLD2-Mediated DNA Double-Strand Break Repair and Regulates Chemoresponse in Cancer.
Li Y, Li L, Wang X, Zhao F, Yang Y, Zhou Y, Zhang J, Wang L, Jiang Z, Zhang Y, Chen Y, Wu C, Li K, Zhang T, Wang P, Mao Z, Zhu W, Xu X, Liang S, Lou Z, Yuan J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2403485
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2403485
HECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction.
Cheng Z, Huang M, Li W, Hou L, Jin L, Fan Q, Zhang L, Li C, Zeng L, Yang C, Liang B, Li F, Chen C
Cell death & disease 2024 Jan 24;15(1):86
Cell death & disease 2024 Jan 24;15(1):86
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.
Zhang G, Tan R, Wan S, Yang R, Hu X, Zhao E, Ding X, Zhang J, Li B, Liang P, Cui H
British journal of cancer 2022 Nov;127(11):1925-1938
British journal of cancer 2022 Nov;127(11):1925-1938
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
Zhang G, Zhu Q, Yan X, Ci M, Zhao E, Hou J, Wan S, Lü M, Cui H
Cell death discovery 2022 Apr 9;8(1):185
Cell death discovery 2022 Apr 9;8(1):185
uc.77- Downregulation Promotes Colorectal Cancer Cell Proliferation by Inhibiting FBXW8-Mediated CDK4 Protein Degradation.
Zheng Z, Hong D, Zhang X, Chang Y, Sun N, Lin Z, Li H, Huang S, Zhang R, Xie Q, Huang H, Jin H
Frontiers in oncology 2021;11:673223
Frontiers in oncology 2021;11:673223
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Gao P, Ma X, Yuan M, Yi Y, Liu G, Wen M, Jiang W, Ji R, Zhu L, Tang Z, Yu Q, Xu J, Yang R, Xia S, Yang M, Pan J, Yuan H, An H
Nature communications 2021 Feb 19;12(1):1194
Nature communications 2021 Feb 19;12(1):1194
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HECTD3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HECTD3. This antibody recognizes human, mouse antigen. The HECTD3 antibody has been validated for the following applications: ELISA, WB analysis.
