Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11487-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11487-1-AP, RRID:AB_2117517
- Product name
- HECTD3 antibody
- Antibody type
- Polyclonal
- Description
- HECTD3 antibody (Cat. #11487-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
uc.77- Downregulation Promotes Colorectal Cancer Cell Proliferation by Inhibiting FBXW8-Mediated CDK4 Protein Degradation.
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Cheng Z, Huang M, Li W, Hou L, Jin L, Fan Q, Zhang L, Li C, Zeng L, Yang C, Liang B, Li F, Chen C
Cell death & disease 2024 Jan 24;15(1):86
Cell death & disease 2024 Jan 24;15(1):86
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.
Zhang G, Tan R, Wan S, Yang R, Hu X, Zhao E, Ding X, Zhang J, Li B, Liang P, Cui H
British journal of cancer 2022 Nov;127(11):1925-1938
British journal of cancer 2022 Nov;127(11):1925-1938
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
Zhang G, Zhu Q, Yan X, Ci M, Zhao E, Hou J, Wan S, Lü M, Cui H
Cell death discovery 2022 Apr 9;8(1):185
Cell death discovery 2022 Apr 9;8(1):185
uc.77- Downregulation Promotes Colorectal Cancer Cell Proliferation by Inhibiting FBXW8-Mediated CDK4 Protein Degradation.
Zheng Z, Hong D, Zhang X, Chang Y, Sun N, Lin Z, Li H, Huang S, Zhang R, Xie Q, Huang H, Jin H
Frontiers in oncology 2021;11:673223
Frontiers in oncology 2021;11:673223
E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Gao P, Ma X, Yuan M, Yi Y, Liu G, Wen M, Jiang W, Ji R, Zhu L, Tang Z, Yu Q, Xu J, Yang R, Xia S, Yang M, Pan J, Yuan H, An H
Nature communications 2021 Feb 19;12(1):1194
Nature communications 2021 Feb 19;12(1):1194
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HECTD3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HECTD3. This antibody recognizes human, mouse antigen. The HECTD3 antibody has been validated for the following applications: ELISA, WB analysis.