Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15584-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15584-1-AP, RRID:AB_2102602
- Product name
- FDXR antibody
- Antibody type
- Polyclonal
- Description
- FDXR antibody (Cat. #15584-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RNA binding protein Pcbp1 maintains mitochondria integrity to promote antibody production and germinal center response.
p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation.
Dissecting the Biological Functions of Various Isoforms of Ferredoxin Reductase for Cell Survival and DNA Damage Response.
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis.
FDXR drives primary and endocrine-resistant tumor cell growth in ER+ breast cancer via CPT1A-mediated fatty acid oxidation.
The neurosteroid pregnenolone is synthesized by a mitochondrial P450 enzyme other than CYP11A1 in human glial cells.
Zhu L, Lin L, Qi T, Li G, Liang Z, Yu J, Fu Y, Peng Y, Chang X
Science advances 2026 Apr 10;12(15):eadz9095
Science advances 2026 Apr 10;12(15):eadz9095
p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation.
Liu X, Qu H, Li J, Sun X, Wang Z, Wang D, Bai X, Li X
Frontiers in oncology 2025;15:1584811
Frontiers in oncology 2025;15:1584811
Dissecting the Biological Functions of Various Isoforms of Ferredoxin Reductase for Cell Survival and DNA Damage Response.
Nakajima KI, Mohibi S, Hong K, Chen X, Zhang J
Cells 2025 Dec 29;15(1)
Cells 2025 Dec 29;15(1)
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis.
Hsiao JC, Warui DM, Kwon JJ, Dreishpoon MB, Bick NR, Blue-Lahom T, Root DE, Booker SJ, Tsvetkov P
Nature communications 2025 Dec 21;17(1):1112
Nature communications 2025 Dec 21;17(1):1112
FDXR drives primary and endocrine-resistant tumor cell growth in ER+ breast cancer via CPT1A-mediated fatty acid oxidation.
Yan C, Gao R, Gao C, Hong K, Cheng M, Liu X, Zhang Q, Zhang J
Frontiers in oncology 2023;13:1105117
Frontiers in oncology 2023;13:1105117
The neurosteroid pregnenolone is synthesized by a mitochondrial P450 enzyme other than CYP11A1 in human glial cells.
Lin YC, Cheung G, Porter E, Papadopoulos V
The Journal of biological chemistry 2022 Jul;298(7):102110
The Journal of biological chemistry 2022 Jul;298(7):102110
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human adrenal gland tissue were subjected to SDS PAGE followed by western blot with 15584-1-AP(FDXR antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15584-1-AP(FDXR antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The FDXR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FDXR. This antibody recognizes human,mouse,rat antigen. The FDXR antibody has been validated for the following applications: ELISA, WB, IHC analysis.