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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [336]
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- Product number
- 67763-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- GPX4 antibody
- Antibody type
- Monoclonal
- Description
- GPX4 antibody (Cat. #67763-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat, rabbit, pig and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine, Rabbit
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3F5G5
- Vial size
- 20ul, 150ul
Submitted references Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.
GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis.
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Surufatinib combined with photodynamic therapy induces ferroptosis to inhibit cholangiocarcinoma in vitro and in tumor models.
Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8(+)T cell function and its impact against pancreatic ductal adenocarcinoma.
Propofol and salvianolic acid A synergistically attenuated cardiac ischemia-reperfusion injury in diabetic mice via modulating the CD36/AMPK pathway.
Unveiling the mechanism of photothermal therapy in acne man-agement: targeting sebaceous gland ferroptosis via umbilical cord mesenchymal stem cell membrane-encapsulated Au-Ag-PDA.
Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells.
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Elucidating the molecular mechanisms behind the therapeutic impact of median nerve stimulation on cognitive dysfunction post-traumatic brain injury.
MiR-1909-5p targeting GPX4 affects the progression of aortic dissection by modulating nicotine-induced ferroptosis.
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
The regulation of GSH/GPX4-mediated lipid accumulation confirms that schisandra polysaccharides should be valued equally as lignans.
Identification of ROS and KEAP1-related genes and verified targets of α-hederin induce cell death for CRC.
Icariin‑curcumol promotes ferroptosis in prostate cancer cells through Nrf2/HO‑1 signaling.
N-acetylcysteine Protects Against Myocardial Ischemia-Reperfusion Injury Through Anti-ferroptosis in Type 1 Diabetic Mice.
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Exploring the anti-ferroptosis mechanism of Kai-Xin-San against Alzheimer's disease through integrating network pharmacology, bioinformatics, and experimental validation strategy in vivo and in vitro.
Cadmium exposure induced neuronal ferroptosis and cognitive deficits via the mtROS-ferritinophagy pathway.
Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling.
MiR-122-5p regulates erastin-induced ferroptosis via CS in nasopharyngeal carcinoma.
Design, synthesis, and evaluation of formylpiperazine analogs of Ferrostatin-1 as novel improved ferroptosis inhibitors.
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Ca & Mn dual-ion hybrid nanostimulator boosting anti-tumor immunity via ferroptosis and innate immunity awakening.
Glutathione depletion and dihydroorotate dehydrogenase inhibition actuated ferroptosis-augment to surmount triple-negative breast cancer.
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion.
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders.
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Biomimetic Nanoarchitectonics with Chitosan Nanogels for Collaborative Induction of Ferroptosis and Anticancer Immunity for Cancer Therapy.
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO-1 Signaling Pathway in Diabetic Nephropathy.
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis.
Mechanism of Dendrobium Nobile Polysaccharide Inhibition of Ferroptosis in Rats with Spinal Cord Injury.
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Tetrahydrobiopterin inhibitor-based antioxidant metabolic strategy for enhanced cancer ferroptosis-immunotherapy.
Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.
Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair.
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Glyphosate drives autophagy-dependent ferroptosis to inhibit testosterone synthesis in mouse Leydig cells.
Acupuncture alleviates CUMS-induced depression-like behaviors of rats by regulating oxidative stress, neuroinflammation and ferroptosis.
Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway.
Cell-Cycle-related Protein Centromere Protein F Deficiency Inhibits Cervical Cancer Cell Growth by Inducing Ferroptosis Via Nrf2 Inactivation.
A Disintegrin and Metalloproteinase-8 Protects Against Erastin-Induced Neuronal Ferroptosis via Activating Nrf2/HO-1/FTH1 Signaling Pathway.
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Photodynamic therapy inhibits cancer progression and induces ferroptosis and apoptosis by targeting P53/GPX4/SLC7A11 signaling pathways in cholangiocarcinoma.
YTHDF2 Promotes Cardiac Ferroptosis via Degradation of SLC7A11 in Cardiac Ischemia-Reperfusion Injury.
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Downregulated GPX4 in salivary gland epithelial cells contributes to salivary secretion dysfunction in Sjogren's syndrome via lipid ROS/pSTAT4/AQP5 axis.
Cu(2)WS(4)-PEG Nanozyme as Multifunctional Sensitizers for Enhancing Immuno-Radiotherapy by Inducing Ferroptosis.
Botulinum toxin A attenuates osteoarthritis development via inhibiting chondrocyte ferroptosis through SLC7Al1/GPX4 axis.
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
MaiJiTong granule attenuates atherosclerosis by reducing ferroptosis via activating STAT6-mediated inhibition of DMT1 and SOCS1/p53 pathways in LDLR(-/-) mice.
Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis.
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition.
Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway.
Exploration and Validation of Ferroptosis-Associated Genes in ADAR1 Deletion-Induced NAFLD through RNA-seq Analysis.
Rack1-mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights.
Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway.
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Ferroptosis: First evidence in premature duck ovary induced by polyvinyl chloride microplastics.
An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal-fetal interface at different days of rat pregnancy.
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Cadmium Induces Kidney Iron Deficiency and Chronic Kidney Injury by Interfering with the Iron Metabolism in Rats.
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease.
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO(2) for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H(2)O(2) self-supply.
AURKA inhibition induces Ewing's sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis.
Sunitinib induces cardiotoxicity through modulating oxidative stress and Nrf2-dependent ferroptosis in vitro and in vivo.
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.
High-Throughput Sequencing to Investigate the Expression and Potential Role of Differentially Expressed microRNAs in Myocardial Cells after Ischemia-Reperfusion Injury.
Rapid and comprehensive metabolites identification of 5-demethylnobiletin in rats using UPLC/Triple-TOF-MS/MS based on multiple mass defect filter and their neuroprotection against ferroptosis.
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Hepatic Alterations in a BTBR T + Itpr3tf/J Mouse Model of Autism and Improvement Using Melatonin via Mitigation Oxidative Stress, Inflammation and Ferroptosis.
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis.
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy.
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Protective effects of melatonin on DEHP-induced apoptosis and oxidative stress in prepubertal testes via the PI3K/AKT pathway.
Se-(Methyl)-selenocysteine ameliorates blood-brain barrier disruption of focal cerebral ischemia mice via ferroptosis inhibition and tight junction upregulation in an Akt/GSK3β-dependent manner.
Fructus Ligustri Lucidi inhibits ferroptosis in ovariectomy‑induced osteoporosis in rats via the Nrf2/HO‑1 signaling pathway.
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis.
Bile acids inhibit ferroptosis sensitivity through activating farnesoid X receptor in gastric cancer cells.
Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation.
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice.
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.
Pterostilbene attenuates heart failure by inhibiting myocardial ferroptosis through SIRT1/GSK-3β/GPX4 signaling pathway.
Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells.
1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature.
Identification and validation of protein biomarkers for predicting gastrointestinal stromal tumor recurrence.
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro.
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc(-)-GSH-GPX4 signaling pathway in ferroptosis response.
PRDX6 augments selenium utilization to limit iron toxicity and ferroptosis.
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
Exploration and validation of therapeutic molecules for rheumatoid arthritis based on ferroptosis-related genes.
Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells.
EGCG-NPs inhibition HO-1-mediated reprogram iron metabolism against ferroptosis after subarachnoid hemorrhage.
PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation.
SIRT5 Regulates Ferroptosis through the Nrf2/HO-1 Signaling Axis to Participate in Ischemia-Reperfusion Injury in Ischemic Stroke.
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy.
GPX4-mediated bone ferroptosis under mechanical stress decreased bone formation via the YAP-TEAD signalling pathway.
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Copper Exposure Induced Chicken Hepatotoxicity: Involvement of Ferroptosis Mediated by Lipid Peroxidation, Ferritinophagy, and Inhibition of FSP1-CoQ10 and Nrf2/SLC7A11/GPX4 Axis.
Identification and validation of an immunotherapeutic signature for colon cancer based on the regulatory patterns of ferroptosis and their association with the tumor microenvironment.
Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis.
Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells.
Chronic Aroclor 1260 exposure alters the mouse liver proteome, selenoproteins, and metals in steatotic liver disease.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis.
ED-71 ameliorates bone regeneration in type 2 diabetes by reducing ferroptosis in osteoblasts via the HIF1α pathway.
Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.
Detection of Ferroptosis in Patient-Derived Tumor Models.
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression.
Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease.
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance.
Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis.
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Integrated Analysis of Ferroptosis and Immunity-Related Genes Associated with Diabetic Kidney Disease.
Identification of Novel Targets for Treatment of Dilated Cardiomyopathy Based on the Ferroptosis and Immune Heterogeneity.
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE(-/-)mice.
Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4.
Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study.
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug.
Activation of Nrf2 inhibits ferroptosis and protects against oxaliplatin-induced ototoxicity.
Ozone pretreatment alleviates ischemiareperfusion injury-induced myocardial ferroptosis by activating the Nrf2/Slc7a11/Gpx4 axis.
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via miR-214-3p.
Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer.
Cadmium exposure promotes ferroptosis by upregulating Heat Shock Protein 70 in vascular endothelial damage of zebrafish.
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology.
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11.
Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase.
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
Sonodynamic Therapy of NRP2 Monoclonal Antibody-Guided MOFs@COF Targeted Disruption of Mitochondrial and Endoplasmic Reticulum Homeostasis to Induce Autophagy-Dependent Ferroptosis.
Use of Deep-Learning Assisted Assessment of Cardiac Parameters in Zebrafish to Discover Cyanidin Chloride as a Novel Keap1 Inhibitor Against Doxorubicin-Induced Cardiotoxicity.
3β-Hydroxy-12-oleanen-27-oic Acid Exerts an Antiproliferative Effect on Human Colon Carcinoma HCT116 Cells via Targeting FDFT1.
The clinical predictive value and regulation mechanism of microRNA-188-5p in contrast-induced acute kidney injury.
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis.
Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer.
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
Heme Oxygenase-1-Modified BMMSCs Activate AMPK-Nrf2-FTH1 to Reduce Severe Steatotic Liver Ischemia-Reperfusion Injury.
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 Activation.
Activation of the Nrf-2 pathway by pinocembrin safeguards vertebral endplate chondrocytes against apoptosis and degeneration caused by oxidative stress.
Acetyl-CoA Acetyltransferase 2 Confers Radioresistance by Inhibiting Ferroptosis in Esophageal Squamous Cell Carcinoma.
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
Polydopamine Nanoparticles Targeting Ferroptosis Mitigate Intervertebral Disc Degeneration Via Reactive Oxygen Species Depletion, Iron Ions Chelation, and GPX4 Ubiquitination Suppression.
Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis.
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
DiDang decoction improves mitochondrial function and lipid metabolism via the HIF-1 signaling pathway to treat atherosclerosis and hyperlipidemia.
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury.
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway.
Reversal of H(2)O(2)-induced cell death by knockdown of HOTAIR in HTR-8/SVneo cells by mediation of miR-106b-5p/ACSL4 axis.
PM(2.5) caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis.
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis.
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells.
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Toosendanin induced hepatotoxicity via triggering PERK-eIF2α-ATF4 mediated ferroptosis.
TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1.
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis.
Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene.
Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis.
Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Ferrostatin-1 alleviates the damage of C2C12 myoblast and mouse pelvic floor muscle induced by mechanical trauma.
The effect of ferroptosis - related proteins and histone deacetylases1 on neoadjuvant chemotherapy in breast cancer.
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling.
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.
Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis.
Dendrobium Nobile Polysaccharides Attenuates Ferroptosis and Improves Cognitive Function in Vascular Dementia Rats.
Yiqi Chutan Formula Reverses Cisplatin-Induced Apoptosis and Ferroptosis of Skeletal Muscle by Alleviating Oxidative Stress.
Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4/xCT signaling pathway.
Berberine hydrochloride alleviates imatinib mesylate - induced cardiotoxicity through the inhibition of Nrf2-dependent ferroptosis.
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Lipocalin 2 induces visual impairment by promoting ferroptosis in retinal ischemia-reperfusion injury.
Glutathione ameliorates the meiotic defects of copper exposed ovine oocytes via inhibiting the mitochondrial dysfunctions.
Triterpenoids from Uncaria macrophylla as ferroptosis inhibitors.
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway.
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway.
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
Xanthohumol attenuates renal ischemia/reperfusion injury by inhibiting ferroptosis.
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Eicosapentaenoic acid enhances the sensitivity of osteosarcoma to cisplatin by inducing ferroptosis through the DNA-PKcs/AKT/NRF2 pathway and reducing PD-L1 expression to attenuate immune evasion.
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.
Imatinib induces ferroptosis in gastrointestinal stromal tumors by promoting STUB1-mediated GPX4 ubiquitination.
Overexpression of FSP1 Ameliorates ferroptosis via PI3K/ AKT /GSK3β pathway in PC12 cells with Oxygen-Glucose Deprivation/Reoxygenation.
A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease.
Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure.
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
MEN1 is a regulator of alternative splicing and prevents R-loop-induced genome instability through suppression of RNA polymerase II elongation.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Overexpression of GPX4 attenuates cognitive dysfunction through inhibiting hippocampus ferroptosis and neuroinflammation after traumatic brain injury.
Targeting the Na(+)/K(+) ATPase DR-region with DR-Ab improves doxorubicin-induced cardiotoxicity.
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury.
Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway.
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway.
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Ferroptosis mediates decabromodiphenyl ether-induced liver damage and inflammation.
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Edaravone Ameliorates Cerebral Ischemia-Reperfusion Injury by Downregulating Ferroptosis via the Nrf2/FPN Pathway in Rats.
Effect of one-time high load exercise on skeletal muscle injury in rats of different genders: oxidative stress and mitochondrial responses.
Attenuation by Time-Restricted Feeding of High-Fat and High-Fructose Diet-Induced NASH in Mice Is Related to Per2 and Ferroptosis.
Cryptotanshinone Protects against PCOS-Induced Damage of Ovarian Tissue via Regulating Oxidative Stress, Mitochondrial Membrane Potential, Inflammation, and Apoptosis via Regulating Ferroptosis.
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
SLC7A11/GPX4 Inactivation-Mediated Ferroptosis Contributes to the Pathogenesis of Triptolide-Induced Cardiotoxicity.
Artemether attenuates renal tubular injury by regulating iron metabolism in mice with streptozotocin-induced diabetes.
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity.
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Glutathione Peroxidase 4 as a Therapeutic Target for Anti-Colorectal Cancer Drug-Tolerant Persister Cells.
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics.
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Hedyotis diffusa injection induces ferroptosis via the Bax/Bcl2/VDAC2/3 axis in lung adenocarcinoma.
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury.
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins.
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma.
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Cadmium induces ferroptosis mediated inflammation by activating Gpx4/Ager/p65 axis in pancreatic β-cells.
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance.
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
Ferritinophagy is Involved in Experimental Subarachnoid Hemorrhage-Induced Neuronal Ferroptosis.
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Notch3 regulates ferroptosis via ROS-induced lipid peroxidation in NSCLC cells.
Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis.
Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats.
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation.
Seco-Lupane Triterpene Derivatives Induce Ferroptosis through GPX4/ACSL4 Axis and Target Cyclin D1 to Block the Cell Cycle.
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Insamgobonhwan Protects Neuronal Cells from Lipid ROS and Improves Deficient Cognitive Function.
A biomimetic nanodrug self-assembled from small molecules for enhanced ferroptosis therapy.
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Comprehensive analysis of placental gene-expression profiles and identification of EGFR-mediated autophagy and ferroptosis suppression in intrahepatic cholestasis of pregnancy.
Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis.
GPX4 suppresses ferroptosis to promote malignant progression of endometrial carcinoma via transcriptional activation by ELK1.
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Ferritinophagic Flux Was a Driving Force in Determination of Status of EMT, Ferroptosis, and NDRG1 Activation in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate S-Acetic Acid.
Calorie Restriction Protects against Contrast-Induced Nephropathy via SIRT1/GPX4 Activation.
Mesenchymal Stem Cells Alleviate Post-resuscitation Cardiac and Cerebral Injuries by Inhibiting Cell Pyroptosis and Ferroptosis in a Swine Model of Cardiac Arrest.
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway.
Chen Y, Shen J, Yuan M, Li H, Li Y, Zheng S, Han B, Zhang C, Liu S, Sun Q, Wu J
Journal of advanced research 2025 Jan;67:331-348
Journal of advanced research 2025 Jan;67:331-348
GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis.
Dang T, Yu J, Yu Y, Jiang J, Shi Y, Yu S, Peng C, Min X, Xiong Y, Long P, Zhou W, Dai D
Cancer biomarkers : section A of Disease markers 2024;39(4):349-360
Cancer biomarkers : section A of Disease markers 2024;39(4):349-360
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38
American journal of translational research 2024;16(1):27-38
Surufatinib combined with photodynamic therapy induces ferroptosis to inhibit cholangiocarcinoma in vitro and in tumor models.
Huang YP, Wang YX, Zhou H, Liu ZT, Zhang ZJ, Xiong L, Zou H, Wen Y
Frontiers in pharmacology 2024;15:1288255
Frontiers in pharmacology 2024;15:1288255
Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8(+)T cell function and its impact against pancreatic ductal adenocarcinoma.
Wei W, Tian L, Zheng X, Zhong L, Chen Y, Dong H, Zhang G, Wang S, Tong X
Oncoimmunology 2024;13(1):2322173
Oncoimmunology 2024;13(1):2322173
Propofol and salvianolic acid A synergistically attenuated cardiac ischemia-reperfusion injury in diabetic mice via modulating the CD36/AMPK pathway.
Zhou J, Xia W, Chen J, Han K, Jiang Y, Zhang A, Zhou D, Liu D, Lin J, Cai Y, Chen G, Zhang L, Xu A, Xu Y, Han R, Xia Z
Burns & trauma 2024;12:tkad055
Burns & trauma 2024;12:tkad055
Unveiling the mechanism of photothermal therapy in acne man-agement: targeting sebaceous gland ferroptosis via umbilical cord mesenchymal stem cell membrane-encapsulated Au-Ag-PDA.
Wu R, Li J, Tian H, Song D, Zhao T, Tian Y, Zouboulis CC, Jiang J, Zhu M
Frontiers in bioengineering and biotechnology 2024;12:1426477
Frontiers in bioengineering and biotechnology 2024;12:1426477
Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells.
Zhang Y, Zheng BY, Zhang QF, Zhao YN, Yu QM, Liu X, Ding SY, Qian SS, Wu H, Wu QY, Zhang YH, Zheng L, Zhang XH, Zhang HF, Hao YM, Lu JC, Wang L, Wen JK, Zheng B
Biomaterials 2024 Sep;309:122613
Biomaterials 2024 Sep;309:122613
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Wang H, Mao W, Zhang Y, Feng W, Bai B, Ji B, Chen J, Cheng B, Yan F
Free radical biology & medicine 2024 Sep;222:331-343
Free radical biology & medicine 2024 Sep;222:331-343
Elucidating the molecular mechanisms behind the therapeutic impact of median nerve stimulation on cognitive dysfunction post-traumatic brain injury.
Zhong YJ, Liu LL, Zhao Y, Feng Z, Liu Y
Experimental gerontology 2024 Sep;194:112500
Experimental gerontology 2024 Sep;194:112500
MiR-1909-5p targeting GPX4 affects the progression of aortic dissection by modulating nicotine-induced ferroptosis.
Tao Y, Li G, Wang Z, Wang S, Peng X, Tang G, Li X, Liu J, Yu T, Fu X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Sep;191:114826
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Sep;191:114826
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Zeng H, Xu J, Wu R, Wang X, Jiang Y, Wang Q, Guo J, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
The regulation of GSH/GPX4-mediated lipid accumulation confirms that schisandra polysaccharides should be valued equally as lignans.
Xue L, Wang L, Xu Y, Shen Y, Shi Z, Li X, Feng H, Xie X, Xie L, Wang G, Liang Y
Journal of ethnopharmacology 2024 Oct 28;333:118483
Journal of ethnopharmacology 2024 Oct 28;333:118483
Identification of ROS and KEAP1-related genes and verified targets of α-hederin induce cell death for CRC.
Wang G, Zhu ZM, Wang K
Drug development research 2024 May;85(3):e22200
Drug development research 2024 May;85(3):e22200
Icariin‑curcumol promotes ferroptosis in prostate cancer cells through Nrf2/HO‑1 signaling.
Sheng W, Li B, Sun T, Zhu C, Li Y, Xu W
Experimental and therapeutic medicine 2024 May;27(5):232
Experimental and therapeutic medicine 2024 May;27(5):232
N-acetylcysteine Protects Against Myocardial Ischemia-Reperfusion Injury Through Anti-ferroptosis in Type 1 Diabetic Mice.
Zhou D, Yang Y, Chen J, Zhou J, He J, Liu D, Zhang A, Yuan B, Jiang Y, Xia W, Han R, Xia Z
Cardiovascular toxicology 2024 May;24(5):481-498
Cardiovascular toxicology 2024 May;24(5):481-498
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Xue P, Zhuang H, Bai T, Zeng X, Deng J, Shao S, Yan S
Journal of nanobiotechnology 2024 May 8;22(1):228
Journal of nanobiotechnology 2024 May 8;22(1):228
Exploring the anti-ferroptosis mechanism of Kai-Xin-San against Alzheimer's disease through integrating network pharmacology, bioinformatics, and experimental validation strategy in vivo and in vitro.
Yan C, Yang S, Shao S, Zu R, Lu H, Chen Y, Zhou Y, Ying X, Xiang S, Zhang P, Li Z, Yuan Y, Zhang Z, Wang P, Xie Z, Wang W, Ma H, Sun Y
Journal of ethnopharmacology 2024 May 23;326:117915
Journal of ethnopharmacology 2024 May 23;326:117915
Cadmium exposure induced neuronal ferroptosis and cognitive deficits via the mtROS-ferritinophagy pathway.
Wang D, Wu Y, Zhou X, Liang C, Ma Y, Yuan Q, Wu Z, Hao X, Zhu X, Li X, Shi J, Chen J, Fan H
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123958
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123958
Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling.
Liang P, Xie W, Wang X, Du Z, Zheng C, Zhao H, Wang Z, Ji Z
International immunopharmacology 2024 May 10;132:111900
International immunopharmacology 2024 May 10;132:111900
MiR-122-5p regulates erastin-induced ferroptosis via CS in nasopharyngeal carcinoma.
Guo L, Wang Z, Fu Y, Wu S, Zhu Y, Yuan J, Liu Y
Scientific reports 2024 May 1;14(1):10019
Scientific reports 2024 May 1;14(1):10019
Design, synthesis, and evaluation of formylpiperazine analogs of Ferrostatin-1 as novel improved ferroptosis inhibitors.
Ji HL, Zhang YF, Zhang NY, Wang KM, Meng N, Zhang J, Jiang CS
Bioorganic & medicinal chemistry 2024 May 1;105:117716
Bioorganic & medicinal chemistry 2024 May 1;105:117716
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Yuan Q, Fang Y, Guo J, Zhang Z, Liao J, Kuang J
Toxicology and applied pharmacology 2024 Mar;484:116845
Toxicology and applied pharmacology 2024 Mar;484:116845
Ca & Mn dual-ion hybrid nanostimulator boosting anti-tumor immunity via ferroptosis and innate immunity awakening.
Deng X, Liu T, Zhu Y, Chen J, Song Z, Shi Z, Chen H
Bioactive materials 2024 Mar;33:483-496
Bioactive materials 2024 Mar;33:483-496
Glutathione depletion and dihydroorotate dehydrogenase inhibition actuated ferroptosis-augment to surmount triple-negative breast cancer.
Zhou TJ, Zhang MM, Liu DM, Huang LL, Yu HQ, Wang Y, Xing L, Jiang HL
Biomaterials 2024 Mar;305:122447
Biomaterials 2024 Mar;305:122447
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Jia C, Wu Y, Gao F, Liu W, Li N, Chen Y, Sun L, Wang S, Yu C, Bao Y, Song Z
Free radical biology & medicine 2024 Mar;214:2-18
Free radical biology & medicine 2024 Mar;214:2-18
Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion.
Zhang LL, Ding K, Liao SS, Zhang YG, Liao HY, Chen R, Meng QT
Free radical biology & medicine 2024 Mar;214:115-128
Free radical biology & medicine 2024 Mar;214:115-128
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Wei Y, Liu W, Wang R, Chen Y, Liu J, Guo X, Can C, Yang X, Wang D, Hu X, Ma D
Free radical biology & medicine 2024 Mar;213:36-51
Free radical biology & medicine 2024 Mar;213:36-51
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
Fu W, Dai C, Ma Z, Li Q, Lan D, Sun C, Wu X, Li J, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Yang Y, Chen Y, Tang H, Zhang Z, Zhou X, Xu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders.
Li X, Hu M, Zhang Y, Hua H, Sun Y, Xiang Q, Zhu D
Bioorganic chemistry 2024 Mar;144:107115
Bioorganic chemistry 2024 Mar;144:107115
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L
British journal of cancer 2024 Mar;130(5):755-768
British journal of cancer 2024 Mar;130(5):755-768
Biomimetic Nanoarchitectonics with Chitosan Nanogels for Collaborative Induction of Ferroptosis and Anticancer Immunity for Cancer Therapy.
Yang N, Pan X, Zhou X, Liu Z, Yang J, Zhang J, Jia Z, Shen Q
Advanced healthcare materials 2024 Mar;13(7):e2302752
Advanced healthcare materials 2024 Mar;13(7):e2302752
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Cheng P, Wang X, Liu Q, Yang T, Dai E, Sha W, Qu H, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO-1 Signaling Pathway in Diabetic Nephropathy.
Wang H, Yu X, Liu D, Qiao Y, Huo J, Pan S, Zhou L, Wang R, Feng Q, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305563
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305563
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Wang Q, He Z, Zhu J, Hu M, Yang L, Yang H
BMC biotechnology 2024 Mar 8;24(1):13
BMC biotechnology 2024 Mar 8;24(1):13
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis.
Zhou XN, Zhang Q, Peng H, Qin YJ, Liu YH, Wang L, Cheng ML, Luo XH, Li H
World journal of gastroenterology 2024 Mar 21;30(11):1588-1608
World journal of gastroenterology 2024 Mar 21;30(11):1588-1608
Mechanism of Dendrobium Nobile Polysaccharide Inhibition of Ferroptosis in Rats with Spinal Cord Injury.
Huang J, Luo J, Huang Y, Wang L, Zhu H, Li Z, Chen J
Journal of integrative neuroscience 2024 Mar 21;23(3):65
Journal of integrative neuroscience 2024 Mar 21;23(3):65
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
Chen Q, Zhang T, Zeng R, Zhang K, Li B, Zhu Z, Ma X, Zhang Y, Li L, Zhu J, Zhang G
Scientific reports 2024 Mar 20;14(1):6655
Scientific reports 2024 Mar 20;14(1):6655
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Wang W, Ma Z, Feng X, Ren J, Sun S, Shao Y, Zhang W, Yang X, Zhang J, Jing X
Arthritis research & therapy 2024 Mar 16;26(1):71
Arthritis research & therapy 2024 Mar 16;26(1):71
Tetrahydrobiopterin inhibitor-based antioxidant metabolic strategy for enhanced cancer ferroptosis-immunotherapy.
Liu Z, Kang R, Yang N, Pan X, Yang J, Yu H, Deng W, Jia Z, Zhang J, Shen Q
Journal of colloid and interface science 2024 Mar 15;658:100-113
Journal of colloid and interface science 2024 Mar 15;658:100-113
Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.
Mohr ME, Li S, Trouten AM, Stairley RA, Roddy PL, Liu C, Zhang M, Sucov HM, Tao G
iScience 2024 Mar 15;27(3):109219
iScience 2024 Mar 15;27(3):109219
Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair.
Li J, Liu T, Tang N, Lin S, Zhang F, Yuan W, Zhang T, Deng SH, Wu DM, Xu Y
Heliyon 2024 Mar 15;10(5):e26975
Heliyon 2024 Mar 15;10(5):e26975
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Zhang J, Jiang J, Wang B, Wang Y, Qian Y, Suo J, Li Y, Peng Z
International immunopharmacology 2024 Mar 10;129:111564
International immunopharmacology 2024 Mar 10;129:111564
Glyphosate drives autophagy-dependent ferroptosis to inhibit testosterone synthesis in mouse Leydig cells.
Lu L, Lian CY, Lv YT, Zhang SH, Wang L, Wang L
The Science of the total environment 2024 Mar 1;914:169927
The Science of the total environment 2024 Mar 1;914:169927
Acupuncture alleviates CUMS-induced depression-like behaviors of rats by regulating oxidative stress, neuroinflammation and ferroptosis.
Shen J, Hao C, Yuan S, Chen W, Tong T, Chen Y, Shahzad Aslam M, Yan S, Li J, Zeng J, Liu S, Chen Y, Jiang Y, Li P, Meng X
Brain research 2024 Mar 1;1826:148715
Brain research 2024 Mar 1;1826:148715
Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway.
Han J, Zhan LN, Huang Y, Guo S, Zhou X, Kapilevich L, Wang Z, Ning K, Sun M, Zhang XA
Scientific reports 2024 Mar 1;14(1):5078
Scientific reports 2024 Mar 1;14(1):5078
Cell-Cycle-related Protein Centromere Protein F Deficiency Inhibits Cervical Cancer Cell Growth by Inducing Ferroptosis Via Nrf2 Inactivation.
Tang XH, Zhao TN, Guo L, Liu XY, Zhang WN, Zhang P
Cell biochemistry and biophysics 2024 Jun;82(2):997-1006
Cell biochemistry and biophysics 2024 Jun;82(2):997-1006
A Disintegrin and Metalloproteinase-8 Protects Against Erastin-Induced Neuronal Ferroptosis via Activating Nrf2/HO-1/FTH1 Signaling Pathway.
Qian Z, Zhang Q, Li P, Li Y, Zhang Y, Li R, Zhao T, Xia M, Chen Y, Hong X
Molecular neurobiology 2024 Jun;61(6):3490-3502
Molecular neurobiology 2024 Jun;61(6):3490-3502
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Lu JS, Wang JH, Han K, Li N
Inflammation 2024 Jun;47(3):975-988
Inflammation 2024 Jun;47(3):975-988
Photodynamic therapy inhibits cancer progression and induces ferroptosis and apoptosis by targeting P53/GPX4/SLC7A11 signaling pathways in cholangiocarcinoma.
Yan X, Li Z, Chen H, Yang F, Tian Q, Zhang Y
Photodiagnosis and photodynamic therapy 2024 Jun;47:104104
Photodiagnosis and photodynamic therapy 2024 Jun;47:104104
YTHDF2 Promotes Cardiac Ferroptosis via Degradation of SLC7A11 in Cardiac Ischemia-Reperfusion Injury.
Pang P, Si W, Wu H, Ju J, Liu K, Wang C, Jia Y, Diao H, Zeng L, Jiang W, Yang Y, Xiong Y, Kong X, Zhang Z, Zhang F, Song J, Wang N, Yang B, Bian Y
Antioxidants & redox signaling 2024 Jun;40(16-18):889-905
Antioxidants & redox signaling 2024 Jun;40(16-18):889-905
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Chen G, Luo S, Guo H, Lin J, Xu S
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Zhang X, Li G, Chen H, Nie XW, Bian JS
Free radical biology & medicine 2024 Jun;218:190-204
Free radical biology & medicine 2024 Jun;218:190-204
Downregulated GPX4 in salivary gland epithelial cells contributes to salivary secretion dysfunction in Sjogren's syndrome via lipid ROS/pSTAT4/AQP5 axis.
Zhou J, Pathak JL, Wu L, Chen B, Cao T, Wei W, Wu X, Chen G, Watanabe N, Li X, Li J
Free radical biology & medicine 2024 Jun;218:1-15
Free radical biology & medicine 2024 Jun;218:1-15
Cu(2)WS(4)-PEG Nanozyme as Multifunctional Sensitizers for Enhancing Immuno-Radiotherapy by Inducing Ferroptosis.
Fu S, Li Y, Shen L, Chen Y, Lu J, Ran Y, Zhao Y, Tang H, Tan L, Lin Q, Hao Y
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2309537
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2309537
Botulinum toxin A attenuates osteoarthritis development via inhibiting chondrocyte ferroptosis through SLC7Al1/GPX4 axis.
Zeng L, Liu Y, Wang Q, Wan H, Meng X, Tu P, Chen H, Luo A, Hu P, Ding X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167215
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167215
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Zhang Q, Zhou J, Zhai D, Jiang Q, Yang M, Zhou M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
Li R, Geng H, Tan X, Wang J, Deng L
The Journal of nutrition 2024 Jun;154(6):1790-1802
The Journal of nutrition 2024 Jun;154(6):1790-1802
MaiJiTong granule attenuates atherosclerosis by reducing ferroptosis via activating STAT6-mediated inhibition of DMT1 and SOCS1/p53 pathways in LDLR(-/-) mice.
Shi J, Yang MM, Yang S, Fan F, Zheng G, Miao Y, Hua Y, Zhang J, Cheng Y, Liu S, Guo Y, Guo L, Yang X, Fan G, Ma C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155489
Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis.
Chai B, Wu Y, Yang H, Fan B, Cao S, Zhang X, Xie Y, Hu Z, Ma Z, Zhang Y, Pan W, Meng W, Meng J, Tian W, Zhang J, Li Y, Shao Y, Wang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(23):e2310134
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(23):e2310134
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Duan WL, Ma YP, Wang XJ, Ma CS, Han B, Sheng ZM, Dong H, Zhang LY, Li PA, Zhang BG, He MT
European journal of pharmacology 2024 Jun 5;972:176553
European journal of pharmacology 2024 Jun 5;972:176553
Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition.
Huang LY, Zhang YD, Liu YN, Liang ZY, Chen J, Wang B, Yin QL, Wang PP, Wang W, Qi SH
ACS chemical neuroscience 2024 Jun 5;15(11):2223-2232
ACS chemical neuroscience 2024 Jun 5;15(11):2223-2232
Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway.
Yu Y, Liang J, Yuan Z, Wang A, Liu X, Chen Y, Zhang M, Gao Y, Zhang H, Liu Y
Journal of ethnopharmacology 2024 Jun 28;328:118135
Journal of ethnopharmacology 2024 Jun 28;328:118135
Exploration and Validation of Ferroptosis-Associated Genes in ADAR1 Deletion-Induced NAFLD through RNA-seq Analysis.
Yin X, Mi Y, Wang X, Li Y, Zhu X, Bukhari I, Wang Q, Zheng P, Xue X, Tang Y
International immunopharmacology 2024 Jun 15;134:112177
International immunopharmacology 2024 Jun 15;134:112177
Rack1-mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights.
Wang CY, Li MY, Li SY, Wei XG, Dong NX, Liu ST, Yuan ZW, Li B, Pierro A, Tang XB, Bai YZ
Cell proliferation 2024 Jul;57(7):e13618
Cell proliferation 2024 Jul;57(7):e13618
Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway.
Liu C, Zhong M, Jin X, Zhu J, Cheng Y, Li L, Xu Q, Liu Q, Ding H, Zhang G
Journal of endocrinological investigation 2024 Jul;47(7):1763-1776
Journal of endocrinological investigation 2024 Jul;47(7):1763-1776
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Chen B, Fu W, Jie C, Zhang G, Li Z, Liu Y, Zhou S
Molecular medicine reports 2024 Jul;30(1)
Molecular medicine reports 2024 Jul;30(1)
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Ma R, Hu K, Dai S, Wang Y
Biochemical and biophysical research communications 2024 Jul 23;718:150037
Biochemical and biophysical research communications 2024 Jul 23;718:150037
Ferroptosis: First evidence in premature duck ovary induced by polyvinyl chloride microplastics.
Ali W, Chen Y, Shah MG, Buriro RS, Sun J, Liu Z, Zou H
The Science of the total environment 2024 Jul 10;933:173032
The Science of the total environment 2024 Jul 10;933:173032
An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal-fetal interface at different days of rat pregnancy.
Tatar M, Tüfekci KK
Anatomia, histologia, embryologia 2024 Jan;53(1):e12991
Anatomia, histologia, embryologia 2024 Jan;53(1):e12991
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Wang W, Yu R, Wu C, Li Q, Chen J, Xiao Y, Chen H, Song J, Ji M, Zuo Z
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Cadmium Induces Kidney Iron Deficiency and Chronic Kidney Injury by Interfering with the Iron Metabolism in Rats.
Zhang K, Long M, Dong W, Li J, Wang X, Liu W, Huang Q, Ping Y, Zou H, Song R, Liu G, Ran D, Liu Z
International journal of molecular sciences 2024 Jan 7;25(2)
International journal of molecular sciences 2024 Jan 7;25(2)
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Liu Y, Pang Z, Wang Y, Liu J, Wang G, Du J
Chemico-biological interactions 2024 Jan 5;387:110794
Chemico-biological interactions 2024 Jan 5;387:110794
Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease.
Li QM, Xu T, Zha XQ, Feng XW, Zhang FY, Luo JP
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117196
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117196
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO(2) for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H(2)O(2) self-supply.
Zhao P, Gong L, Chang L, Du H, Geng M, Meng S, Dai L
Journal of nanobiotechnology 2024 Jan 3;22(1):3
Journal of nanobiotechnology 2024 Jan 3;22(1):3
AURKA inhibition induces Ewing's sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis.
Chen H, Hu J, Xiong X, Chen H, Lin B, Chen Y, Li Y, Cheng D, Li Z
Cell death & disease 2024 Jan 29;15(1):99
Cell death & disease 2024 Jan 29;15(1):99
Sunitinib induces cardiotoxicity through modulating oxidative stress and Nrf2-dependent ferroptosis in vitro and in vivo.
Li D, Song C, Song C, Tian X, Zhang H, Zhang J, Zhao X
Chemico-biological interactions 2024 Jan 25;388:110829
Chemico-biological interactions 2024 Jan 25;388:110829
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.
Wu W, Li G, Dong S, Huihan Chu C, Ma S, Zhang Z, Yuan S, Wu J, Guo Z, Shen Y, Wang J, Tang C
International immunopharmacology 2024 Jan 25;127:111423
International immunopharmacology 2024 Jan 25;127:111423
High-Throughput Sequencing to Investigate the Expression and Potential Role of Differentially Expressed microRNAs in Myocardial Cells after Ischemia-Reperfusion Injury.
Li S, Lv D, Lu Y, Zhang Y, Jia Y
Frontiers in bioscience (Landmark edition) 2024 Jan 23;29(1):38
Frontiers in bioscience (Landmark edition) 2024 Jan 23;29(1):38
Rapid and comprehensive metabolites identification of 5-demethylnobiletin in rats using UPLC/Triple-TOF-MS/MS based on multiple mass defect filter and their neuroprotection against ferroptosis.
Yuan S, Gao P, Wu S, Liang X, Xiao Y, Tu P, Jiang Y
Journal of pharmaceutical and biomedical analysis 2024 Jan 20;238:115842
Journal of pharmaceutical and biomedical analysis 2024 Jan 20;238:115842
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Tao H, Song SJ, Fan ZW, Li WT, Jin X, Jiang W, Bai J, Shi ZZ
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Hepatic Alterations in a BTBR T + Itpr3tf/J Mouse Model of Autism and Improvement Using Melatonin via Mitigation Oxidative Stress, Inflammation and Ferroptosis.
Rezzani R, Gianò M, Pinto D, Rinaldi F, van Noorden CJF, Favero G
International journal of molecular sciences 2024 Jan 16;25(2)
International journal of molecular sciences 2024 Jan 16;25(2)
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Yu S, Xiong W, Xu W, Chen Y
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Zou W, Wang X, Xia X, Zhang T, Nie M, Xiong J, Fang X
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Lv Y, Liu Z, Deng L, Xia S, Mu Q, Xiao B, Xiu Y, Liu Z
Scientific reports 2024 Jan 10;14(1):1009
Scientific reports 2024 Jan 10;14(1):1009
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002
Redox biology 2024 Feb;69:103002
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Wang S, Xiong B, Tian Y, Hu Q, Jiang X, Zhang J, Chen L, Wang R, Li M, Zhou X, Zhang T, Ge H, Yu A
Molecular neurobiology 2024 Feb;61(2):1157-1174
Molecular neurobiology 2024 Feb;61(2):1157-1174
Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis.
Chen J, Zhang R, Li F, Lin S, Wang J
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Feb;56(2):281-290
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Feb;56(2):281-290
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy.
Ma Z, Lu H, Feng X, Du T, Li J, Zhang Q, Gu X, Shao Y, Jing X, Su C
International journal of molecular medicine 2024 Feb;53(2)
International journal of molecular medicine 2024 Feb;53(2)
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J
Oncology reports 2024 Feb;51(2)
Oncology reports 2024 Feb;51(2)
Protective effects of melatonin on DEHP-induced apoptosis and oxidative stress in prepubertal testes via the PI3K/AKT pathway.
Chen J, Zhao T, Zheng X, Kang L, Wang J, Wei Y, Wu Y, Shen L, Long C, Wei G, Wu S
Environmental toxicology 2024 Feb;39(2):952-964
Environmental toxicology 2024 Feb;39(2):952-964
Se-(Methyl)-selenocysteine ameliorates blood-brain barrier disruption of focal cerebral ischemia mice via ferroptosis inhibition and tight junction upregulation in an Akt/GSK3β-dependent manner.
Fei Y, Li T, Wu R, Xu X, Hu S, Yang Y, Jin C, Tang W, Zhang X, Du Q, Liu C
Psychopharmacology 2024 Feb;241(2):379-399
Psychopharmacology 2024 Feb;241(2):379-399
Fructus Ligustri Lucidi inhibits ferroptosis in ovariectomy‑induced osteoporosis in rats via the Nrf2/HO‑1 signaling pathway.
Li P, Wang Y, Yan Q, Yang Y, Zhu R, Ma J, Chen Y, Liu H, Zhang Z
Biomedical reports 2024 Feb;20(2):27
Biomedical reports 2024 Feb;20(2):27
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis.
Li Z, Wu B, Chen J, Ye N, Ma R, Song C, Sun Y, Zhang X, Sun G
Journal of translational internal medicine 2024 Feb;12(1):35-50
Journal of translational internal medicine 2024 Feb;12(1):35-50
Bile acids inhibit ferroptosis sensitivity through activating farnesoid X receptor in gastric cancer cells.
Liu CX, Gao Y, Xu XF, Jin X, Zhang Y, Xu Q, Ding HX, Li BJ, Du FK, Li LC, Zhong MW, Zhu JK, Zhang GY
World journal of gastroenterology 2024 Feb 7;30(5):485-498
World journal of gastroenterology 2024 Feb 7;30(5):485-498
Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
Pan Z, Li B, Lu P, Rong G, Wang X
Gene 2024 Feb 5;894:148026
Gene 2024 Feb 5;894:148026
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Dai Y, Zhang H, Feng S, Guo C, Tian W, Sun Y, Zhang Y
Heliyon 2024 Feb 29;10(4):e25716
Heliyon 2024 Feb 29;10(4):e25716
SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation.
Yan Y, Yuan N, Chen Y, Ma Y, Chen A, Wang F, Yan S, He Z, He J, Zhang C, Wang H, Wang M, Diao J, Xiao W
Chinese medicine 2024 Feb 25;19(1):31
Chinese medicine 2024 Feb 25;19(1):31
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice.
Xiong Y, Liu X, Jiang L, Hao T, Wang Y, Li T
Journal of translational medicine 2024 Feb 24;22(1):199
Journal of translational medicine 2024 Feb 24;22(1):199
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
Yi L, Yang Y, Hu Y, Wu Z, Kong M, Zuoyuan B, Xin X, Yang Z
Free radical biology & medicine 2024 Feb 20;212:349-359
Free radical biology & medicine 2024 Feb 20;212:349-359
P21 resists ferroptosis in osteoarthritic chondrocytes by regulating GPX4 protein stability.
Zheng Z, Shang X, Sun K, Hou Y, Zhang X, Xu J, Liu H, Ruan Z, Hou L, Guo Z, Wang G, Xu F, Guo F
Free radical biology & medicine 2024 Feb 20;212:336-348
Free radical biology & medicine 2024 Feb 20;212:336-348
Pterostilbene attenuates heart failure by inhibiting myocardial ferroptosis through SIRT1/GSK-3β/GPX4 signaling pathway.
Zhang F, Zeng Z, Zhang J, Li X, Yang W, Wei Y, Guo X
Heliyon 2024 Feb 15;10(3):e24562
Heliyon 2024 Feb 15;10(3):e24562
Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells.
Zhang F, Hao Y, Yang N, Liu M, Luo Y, Zhang Y, Zhou J, Liu H, Li J
BMC cancer 2024 Feb 12;24(1):198
BMC cancer 2024 Feb 12;24(1):198
1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature.
Tonelotto V, Costa-Garcia M, O'Reilly E, Smith KF, Slater K, Dillon ET, Pendino M, Higgins C, Sist P, Bosch R, Passamonti S, Piulats JM, Villanueva A, Tramer F, Vanella L, Carey M, Kennedy BN
Cell death discovery 2024 Feb 10;10(1):70
Cell death discovery 2024 Feb 10;10(1):70
Identification and validation of protein biomarkers for predicting gastrointestinal stromal tumor recurrence.
Sun J, Li J, He Y, Kang W, Ye X
Computational and structural biotechnology journal 2024 Dec;23:1065-1075
Computational and structural biotechnology journal 2024 Dec;23:1065-1075
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro.
Wu X, Wu J
Cancer chemotherapy and pharmacology 2024 Aug;94(2):183-195
Cancer chemotherapy and pharmacology 2024 Aug;94(2):183-195
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc(-)-GSH-GPX4 signaling pathway in ferroptosis response.
Ni X, Gao C, Zhu X, Zhang X, Fang Y, Hao Z
Journal of applied toxicology : JAT 2024 Aug;44(8):1139-1152
Journal of applied toxicology : JAT 2024 Aug;44(8):1139-1152
PRDX6 augments selenium utilization to limit iron toxicity and ferroptosis.
Fujita H, Tanaka YK, Ogata S, Suzuki N, Kuno S, Barayeu U, Akaike T, Ogra Y, Iwai K
Nature structural & molecular biology 2024 Aug;31(8):1277-1285
Nature structural & molecular biology 2024 Aug;31(8):1277-1285
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM
bioRxiv : the preprint server for biology 2024 Aug 27;
bioRxiv : the preprint server for biology 2024 Aug 27;
Exploration and validation of therapeutic molecules for rheumatoid arthritis based on ferroptosis-related genes.
Aihaiti Y, Zheng H, Cai Y, Tuerhong X, Kaerman M, Wang F, Xu P
Life sciences 2024 Aug 15;351:122780
Life sciences 2024 Aug 15;351:122780
Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells.
Dai W, Xu B, Ding L, Zhang Z, Yang H, He T, Liu L, Pei X, Fu X
Free radical biology & medicine 2024 Aug 1;220:1-14
Free radical biology & medicine 2024 Aug 1;220:1-14
EGCG-NPs inhibition HO-1-mediated reprogram iron metabolism against ferroptosis after subarachnoid hemorrhage.
Huang L, Wang X, Zheng Y, Lang D, Wang J, Yan S, Chen Y
Redox biology 2024 Apr;70:103075
Redox biology 2024 Apr;70:103075
PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation.
Xiong J, Zhou R, Deng X
In vitro cellular & developmental biology. Animal 2024 Apr;60(4):354-364
In vitro cellular & developmental biology. Animal 2024 Apr;60(4):354-364
SIRT5 Regulates Ferroptosis through the Nrf2/HO-1 Signaling Axis to Participate in Ischemia-Reperfusion Injury in Ischemic Stroke.
Li J, Wei G, Song Z, Chen Z, Gu J, Zhang L, Wang Z
Neurochemical research 2024 Apr;49(4):998-1007
Neurochemical research 2024 Apr;49(4):998-1007
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.
Yao T, Yao YY, Wang JZ, Jiang SM, Li LJ
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
Zhao C, Yu Y, Yin G, Xu C, Wang J, Wang L, Zhao G, Ni S, Zhang H, Zhou B, Wang Y
Inflammopharmacology 2024 Apr;32(2):1277-1294
Inflammopharmacology 2024 Apr;32(2):1277-1294
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy.
Du Y, Zhou Y, Yan X, Pan F, He L, Guo Z, Hu Z
Cell death and differentiation 2024 Apr;31(4):431-446
Cell death and differentiation 2024 Apr;31(4):431-446
GPX4-mediated bone ferroptosis under mechanical stress decreased bone formation via the YAP-TEAD signalling pathway.
Mengjia W, Jun J, Xin Z, Jiahao Z, Jie G
Journal of cellular and molecular medicine 2024 Apr;28(7):e18231
Journal of cellular and molecular medicine 2024 Apr;28(7):e18231
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
Shen X, Peng Y, Zhou H, Ye X, Han Z, Shi X
Journal of inorganic biochemistry 2024 Apr;253:112502
Journal of inorganic biochemistry 2024 Apr;253:112502
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Liu J, Duangjan C, Irwin RW, Curran SP
Mechanisms of ageing and development 2024 Apr;218:111914
Mechanisms of ageing and development 2024 Apr;218:111914
Copper Exposure Induced Chicken Hepatotoxicity: Involvement of Ferroptosis Mediated by Lipid Peroxidation, Ferritinophagy, and Inhibition of FSP1-CoQ10 and Nrf2/SLC7A11/GPX4 Axis.
Zhong G, Li Y, Ma F, Huo Y, Liao J, Han Q, Hu L, Tang Z
Biological trace element research 2024 Apr;202(4):1711-1721
Biological trace element research 2024 Apr;202(4):1711-1721
Identification and validation of an immunotherapeutic signature for colon cancer based on the regulatory patterns of ferroptosis and their association with the tumor microenvironment.
Liu Y, Zhao J, Huang B, Liang Y, Jiang G, Zhou X, Chen Y, He T, Zheng M, Huang Z
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119698
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119698
Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis.
Wu X, Guan Y, Wang J, Song L, Zhang Y, Wang Y, Li Y, Qin L, He Q, Zhang T, Long B, Ji L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155340
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155340
Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells.
Geng N, Dong S, Xie P, Zhang Y, Shi R, Chen C, Xu Z, Chen Q
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108556
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108556
Chronic Aroclor 1260 exposure alters the mouse liver proteome, selenoproteins, and metals in steatotic liver disease.
Piell KM, Petri BJ, Xu J, Cai L, Rai SN, Li M, Wilkey DW, Merchant ML, Cave MC, Klinge CM
Environmental toxicology and pharmacology 2024 Apr;107:104430
Environmental toxicology and pharmacology 2024 Apr;107:104430
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
Song T, Yu Z, Shen Q, Xu Y, Hu H, Liu J, Zeng K, Lei J, Yu L
Cancers 2024 Apr 23;16(9)
Cancers 2024 Apr 23;16(9)
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis.
Zhang D, Li Z, Gao Y, Sun H
Aging 2024 Apr 19;16(8):7277-7292
Aging 2024 Apr 19;16(8):7277-7292
ED-71 ameliorates bone regeneration in type 2 diabetes by reducing ferroptosis in osteoblasts via the HIF1α pathway.
Wang M, Liu Y, Gui H, Ma G, Li B, Zhang Z, Yu G, Wu A, Xu X, Zhang D
European journal of pharmacology 2024 Apr 15;969:176303
European journal of pharmacology 2024 Apr 15;969:176303
Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.
Sun M, Chang H, Jiang F, Zhang W, Yang Q, Wang X, Lv G, Lin H, Luo H, Lin Z, Wang Y
Molecules (Basel, Switzerland) 2024 Apr 11;29(8)
Molecules (Basel, Switzerland) 2024 Apr 11;29(8)
Detection of Ferroptosis in Patient-Derived Tumor Models.
Zhang W, Wang Y
Methods in molecular biology (Clifton, N.J.) 2023;2712:187-197
Methods in molecular biology (Clifton, N.J.) 2023;2712:187-197
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Chen Y, Zhang H, Li Y, Wang T
Oxidative medicine and cellular longevity 2023;2023:8258354
Oxidative medicine and cellular longevity 2023;2023:8258354
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Zhou Y, Qian W, Li X, Wei W
Oxidative medicine and cellular longevity 2023;2023:7098313
Oxidative medicine and cellular longevity 2023;2023:7098313
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression.
Chen H, Li Z, Xu J, Zhang N, Chen J, Wang G, Zhao Y
Oxidative medicine and cellular longevity 2023;2023:6896790
Oxidative medicine and cellular longevity 2023;2023:6896790
Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease.
Pan W, Xiang L, Liang X, Du W, Zhao J, Zhang S, Zhou X, Geng L, Gong S, Xu W
Mediators of inflammation 2023;2023:6623329
Mediators of inflammation 2023;2023:6623329
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
Zhou C, Yu T, Zhu R, Lu J, Ouyang X, Zhang Z, Chen Q, Li J, Cui J, Jiang F, Jin KY, Sarapultsev A, Li F, Zhang G, Luo S, Hu D
International journal of biological sciences 2023;19(5):1471-1489
International journal of biological sciences 2023;19(5):1471-1489
Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance.
Lai Q, Wu L, Dong S, Zhu X, Fan Z, Kou J, Liu F, Yu B, Li F
International journal of biological sciences 2023;19(10):3077-3098
International journal of biological sciences 2023;19(10):3077-3098
Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis.
Cheng Z, Zhang X, Chen P, Wang H, Wang K, Shen Y
Open life sciences 2023;18(1):20220781
Open life sciences 2023;18(1):20220781
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Yin X, Yang Q, Li H, Kang Y, Li Z
Drug design, development and therapy 2023;17:283-295
Drug design, development and therapy 2023;17:283-295
Integrated Analysis of Ferroptosis and Immunity-Related Genes Associated with Diabetic Kidney Disease.
Wang J, Wang L, Pang Z, Ge Q, Wu Y, Qi X
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3773-3793
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:3773-3793
Identification of Novel Targets for Treatment of Dilated Cardiomyopathy Based on the Ferroptosis and Immune Heterogeneity.
Lu H, Xie Y, Zhou Z, Hong P, Chen J
Journal of inflammation research 2023;16:2461-2476
Journal of inflammation research 2023;16:2461-2476
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Gao Y, Zhang Z, Du J, Yang X, Wang X, Wen K, Sun X
Frontiers in pharmacology 2023;14:1148770
Frontiers in pharmacology 2023;14:1148770
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Liu X, Peng X, Cen S, Yang C, Ma Z, Shi X
Frontiers in pharmacology 2023;14:1129662
Frontiers in pharmacology 2023;14:1129662
Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE(-/-)mice.
Xiang P, Chen Q, Chen L, Lei J, Yuan Z, Hu H, Lu Y, Wang X, Wang T, Yu R, Zhang W, Zhang J, Yu C, Ma L
Theranostics 2023;13(14):4993-5016
Theranostics 2023;13(14):4993-5016
Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4.
Jia C, Zhang X, Qu T, Wu X, Li Y, Zhao Y, Sun L, Wang Q
PeerJ 2023;11:e14654
PeerJ 2023;11:e14654
Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study.
Sun H, Peng G, Chen K, Xiong Z, Zhuang Y, Liu M, Ning X, Yang H, Deng J
Heliyon 2023 Sep;9(9):e19975
Heliyon 2023 Sep;9(9):e19975
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Zhang YQ, Shi CX, Zhang DM, Zhang LY, Wang LW, Gong ZJ
Journal of integrative medicine 2023 Sep;21(5):464-473
Journal of integrative medicine 2023 Sep;21(5):464-473
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug.
Huang Y, Lin Y, Li B, Zhang F, Zhan C, Xie X, Yao Z, Wu C, Ping Y, Shen J
Asian journal of pharmaceutical sciences 2023 Sep;18(5):100844
Asian journal of pharmaceutical sciences 2023 Sep;18(5):100844
Activation of Nrf2 inhibits ferroptosis and protects against oxaliplatin-induced ototoxicity.
Xu K, Chang X, Bai X, Liu HB, Chen XB, Chen HP, Liu YH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115248
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115248
Ozone pretreatment alleviates ischemiareperfusion injury-induced myocardial ferroptosis by activating the Nrf2/Slc7a11/Gpx4 axis.
Ding S, Duanmu X, Xu L, Zhu L, Wu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115185
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115185
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Chen P, Wang D, Xiao T, Gu W, Yang H, Yang M, Wang H
International immunopharmacology 2023 Sep;122:110629
International immunopharmacology 2023 Sep;122:110629
Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via miR-214-3p.
Zuo H, Wang Y, Yuan M, Zheng W, Tian X, Pi Y, Zhang X, Song H
Cellular signalling 2023 Sep;109:110793
Cellular signalling 2023 Sep;109:110793
Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer.
Deng C, Xiong L, Chen Y, Wu K, Wu J
BMC pulmonary medicine 2023 Sep 25;23(1):360
BMC pulmonary medicine 2023 Sep 25;23(1):360
Cadmium exposure promotes ferroptosis by upregulating Heat Shock Protein 70 in vascular endothelial damage of zebrafish.
Zhang T, Yan W, Liu C, Duan W, Duan Y, Li Y, Yu Q, Sun Y, Tian J, Zhou J, Xia Z, Wang G, Xu S
Ecotoxicology and environmental safety 2023 Sep 15;263:115241
Ecotoxicology and environmental safety 2023 Sep 15;263:115241
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
Liu Z, Wang X, Li J, Yang X, Huang J, Ji C, Li X, Li L, Zhou J, Hu Y
Chemico-biological interactions 2023 Sep 1;382:110602
Chemico-biological interactions 2023 Sep 1;382:110602
An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology.
Ni W, Zhang H, Mei Z, Hongyi Z, Wu Y, Xu W, Ma Y, Yang W, Liang Y, Gu T, Su Y, Fan S, Shen S, Hu Z
Redox biology 2023 Oct;66:102858
Redox biology 2023 Oct;66:102858
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11.
Lin S, Cheng H, Yang G, Wang C, Leung CK, Zhang S, Tan Y, Zhang H, Wang H, Miao L, Li Y, Huang Y, Li J, Zhang R, Zeng X
Neurotoxicity research 2023 Oct;41(5):398-407
Neurotoxicity research 2023 Oct;41(5):398-407
Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase.
Liu L, Zhang Y, Wang L, Liu Y, Chen H, Hu Q, Xie C, Meng X, Shen X
Phytotherapy research : PTR 2023 Oct;37(10):4587-4606
Phytotherapy research : PTR 2023 Oct;37(10):4587-4606
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
Zhang L, Luo Y, Lv L, Chen S, Liu G, Zhao T
Cell death and differentiation 2023 Oct;30(10):2336-2350
Cell death and differentiation 2023 Oct;30(10):2336-2350
Sonodynamic Therapy of NRP2 Monoclonal Antibody-Guided MOFs@COF Targeted Disruption of Mitochondrial and Endoplasmic Reticulum Homeostasis to Induce Autophagy-Dependent Ferroptosis.
Zhao Z, Wu Y, Liang X, Liu J, Luo Y, Zhang Y, Li T, Liu C, Luo X, Chen J, Wang Y, Wang S, Wu T, Zhang S, Yang D, Li W, Yan J, Ke Z, Luo F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303872
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303872
Use of Deep-Learning Assisted Assessment of Cardiac Parameters in Zebrafish to Discover Cyanidin Chloride as a Novel Keap1 Inhibitor Against Doxorubicin-Induced Cardiotoxicity.
Liu C, Wang Y, Zeng Y, Kang Z, Zhao H, Qi K, Wu H, Zhao L, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2301136
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2301136
3β-Hydroxy-12-oleanen-27-oic Acid Exerts an Antiproliferative Effect on Human Colon Carcinoma HCT116 Cells via Targeting FDFT1.
Tu J, Meng X, Wang J, Han Z, Yu Z, Sun H
International journal of molecular sciences 2023 Oct 9;24(19)
International journal of molecular sciences 2023 Oct 9;24(19)
The clinical predictive value and regulation mechanism of microRNA-188-5p in contrast-induced acute kidney injury.
Yu R, Wu C, Xiao Y, Li Q, Chen J, Song J, Chen H, Wang Z, Wang W
Biochemical and biophysical research communications 2023 Oct 30;679:215-223
Biochemical and biophysical research communications 2023 Oct 30;679:215-223
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway.
Zhao F, Peng C, Li H, Chen H, Yang Y, Ai Q, Chen N, Liu F
Journal of ethnopharmacology 2023 Oct 28;315:116567
Journal of ethnopharmacology 2023 Oct 28;315:116567
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis.
He X, Yang L, Wang M, Zhang P, Wang R, Ji D, Gao C, Xia Z
Biochemical and biophysical research communications 2023 Oct 20;678:11-16
Biochemical and biophysical research communications 2023 Oct 20;678:11-16
Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer.
Yu Y, Huang X, Liang C, Zhang P
European journal of pharmacology 2023 Oct 15;957:176007
European journal of pharmacology 2023 Oct 15;957:176007
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
Luo Q, Zheng J, Fan B, Liu J, Liao W, Zhang X
Brain research bulletin 2023 Oct 15;203:110778
Brain research bulletin 2023 Oct 15;203:110778
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Liu J, Duangjan C, Irwin RW, Curran SP
bioRxiv : the preprint server for biology 2023 Oct 11;
bioRxiv : the preprint server for biology 2023 Oct 11;
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
Zhang H, Gong J, Zhang S, Luo L, Luo C, Bi K, Wang L, Kan X, Tian Z, Wang X
Heliyon 2023 Nov;9(11):e21235
Heliyon 2023 Nov;9(11):e21235
Heme Oxygenase-1-Modified BMMSCs Activate AMPK-Nrf2-FTH1 to Reduce Severe Steatotic Liver Ischemia-Reperfusion Injury.
Tian X, Wang Y, Yuan M, Zheng W, Zuo H, Zhang X, Song H
Digestive diseases and sciences 2023 Nov;68(11):4196-4211
Digestive diseases and sciences 2023 Nov;68(11):4196-4211
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
Chen X, Chen J, Miao C, Yin G, Zhang Z, Sun R, Ni S
Molecular medicine reports 2023 Nov;28(5)
Molecular medicine reports 2023 Nov;28(5)
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Yu Z, Cheng X, Pan W, Yu C, Duan Y
Neural regeneration research 2023 Nov;18(11):2482-2488
Neural regeneration research 2023 Nov;18(11):2482-2488
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 Activation.
Li JJ, Dai WQ, Mo WH, Xu WQ, Li YY, Guo CY, Xu XF
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1341-1354
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1341-1354
Activation of the Nrf-2 pathway by pinocembrin safeguards vertebral endplate chondrocytes against apoptosis and degeneration caused by oxidative stress.
Wang H, Liu X, Yang H, Jing X, Wang W, Liu X, Zhang B, Liu X, Shao Y, Cui X
Life sciences 2023 Nov 15;333:122162
Life sciences 2023 Nov 15;333:122162
Acetyl-CoA Acetyltransferase 2 Confers Radioresistance by Inhibiting Ferroptosis in Esophageal Squamous Cell Carcinoma.
Heng J, Li Z, Liu L, Zheng Z, Zheng Y, Xu X, Liao L, Xu H, Huang H, Li E, Xu L
International journal of radiation oncology, biology, physics 2023 Nov 15;117(4):966-978
International journal of radiation oncology, biology, physics 2023 Nov 15;117(4):966-978
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Wang Y, Xie K, Chen W, Fang Y, Mo Q, Zhang H, Zhao X, Li D, Tan W, Zhao P, Li F
Bioengineering & translational medicine 2023 May;8(3):e10515
Bioengineering & translational medicine 2023 May;8(3):e10515
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Wang K, Li Z, Ding Y, Liu Z, Li Y, Liu X, Sun Y, Hong J, Zheng W, Qian L, Xu D
Journal of physiology and biochemistry 2023 May;79(2):341-353
Journal of physiology and biochemistry 2023 May;79(2):341-353
MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.
Mao Y, Wang M, Xiong Y, Wen X, Zhang M, Ma L, Zhang Y
Reproductive sciences (Thousand Oaks, Calif.) 2023 May;30(5):1506-1520
Reproductive sciences (Thousand Oaks, Calif.) 2023 May;30(5):1506-1520
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Ding S, Jiang J, Zhang G, Yu M, Zheng Y
Ecotoxicology and environmental safety 2023 May;256:114897
Ecotoxicology and environmental safety 2023 May;256:114897
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Li R, Zhang X, Gu L, Yuan Y, Luo X, Shen W, Xie Z
Journal of neurochemistry 2023 May;165(3):426-444
Journal of neurochemistry 2023 May;165(3):426-444
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Hu G, Yuan Z, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114333
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114333
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
Li H, Deng C, Zhu N, Zhang C, Zeng Q, Qin L
Bioorganic chemistry 2023 May;134:106454
Bioorganic chemistry 2023 May;134:106454
Polydopamine Nanoparticles Targeting Ferroptosis Mitigate Intervertebral Disc Degeneration Via Reactive Oxygen Species Depletion, Iron Ions Chelation, and GPX4 Ubiquitination Suppression.
Yang X, Chen Y, Guo J, Li J, Zhang P, Yang H, Rong K, Zhou T, Fu J, Zhao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(13):e2207216
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(13):e2207216
Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis.
Li L, Wang MY, Jiang HB, Guo CR, Zhu XD, Yao XQ, Zeng WW, Zhao Y, Chi LK
Asian journal of andrology 2023 May-Jun;25(3):375-381
Asian journal of andrology 2023 May-Jun;25(3):375-381
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Xiong D, Hu W, Han X, Cai Y
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
DiDang decoction improves mitochondrial function and lipid metabolism via the HIF-1 signaling pathway to treat atherosclerosis and hyperlipidemia.
Wu X, Pan J, Yu JJ, Kang J, Hou S, Cheng M, Xu L, Gong L, Li Y
Journal of ethnopharmacology 2023 May 23;308:116289
Journal of ethnopharmacology 2023 May 23;308:116289
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m(6)A-dependent recognition of Nrf2 mRNA mediated by SND1.
Zheng J, Zhang Q, Zhao Z, Qiu Y, Zhou Y, Wu Z, Jiang C, Wang X, Jiang X
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127
Journal of experimental & clinical cancer research : CR 2023 May 19;42(1):127
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury.
Sun X, Huang N, Li P, Dong X, Yang J, Zhang X, Zong WX, Gao S, Xin H
Life sciences 2023 May 15;321:121608
Life sciences 2023 May 15;321:121608
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway.
Liu Q, Xu L, Ren G, Zhao J, Shao Y, Lu T
Life sciences 2023 May 15;321:121591
Life sciences 2023 May 15;321:121591
Reversal of H(2)O(2)-induced cell death by knockdown of HOTAIR in HTR-8/SVneo cells by mediation of miR-106b-5p/ACSL4 axis.
Cao M, Jin W, Li Y, Wang M, Wan F, Ren Y, Gu Y, Ma J, Zhang L
Functional & integrative genomics 2023 May 15;23(2):161
Functional & integrative genomics 2023 May 15;23(2):161
PM(2.5) caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis.
Wang J, Zhang Z, Shi F, Li Y, Tang Y, Liu C, Wang Y, Chen J, Jiang X, Yang H, Sun L, Chen Q, Ao L, Han F, Liu J, Cao J
The Science of the total environment 2023 May 10;872:162089
The Science of the total environment 2023 May 10;872:162089
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Zeng Y, Wu R, Wang F, Li S, Li L, Li Y, Qin P, Wei M, Yang J, Wu J, Chen A, Ke G, Yan Z, Yang H, Chen Z, Wang Z, Xiao W, Jiang Y, Chen X, Zeng Z, Zhao X, Chen P, Gong S
Cell host & microbe 2023 May 10;31(5):766-780.e7
Cell host & microbe 2023 May 10;31(5):766-780.e7
Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis.
Liu Y, Chen W, Cen Y, Zhao X, Chen Z, Liang Y, Huang Z, He X, Yang G
Chemico-biological interactions 2023 May 1;376:110439
Chemico-biological interactions 2023 May 1;376:110439
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Xu W, Ding J, Li B, Sun T, You X, He Q, Sheng W
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
Lai K, Song C, Gao M, Deng Y, Lu Z, Li N, Geng Q
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Wang Q, Ke S, Liu Z, Shao H, He M, Guo J
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells.
Zhao X, Zhang S, Gao S, Chang HM, Leung PCK, Tan J
ACS applied materials & interfaces 2023 Mar 29;15(12):15084-15095
ACS applied materials & interfaces 2023 Mar 29;15(12):15084-15095
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Cui X, Liu X, Kong P, Du T, Li T, Yang G, Zhang W, Jing X, Wang W
Aging 2023 Mar 24;15(6):2275-2292
Aging 2023 Mar 24;15(6):2275-2292
Toosendanin induced hepatotoxicity via triggering PERK-eIF2α-ATF4 mediated ferroptosis.
Liang Y, Chen S, Han S, Luo L, Shen F, Huang Z
Toxicology letters 2023 Mar 15;377:51-61
Toxicology letters 2023 Mar 15;377:51-61
TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1.
Wei J, Wang L, Zhang Y, Sun T, Zhang C, Hu Z, Zhou L, Liu X, Wan J, Ma L
Oncogene 2023 Jun;42(26):2103-2112
Oncogene 2023 Jun;42(26):2103-2112
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
Zhang M, Wang L, Jin H, Zhao N, Liu Y, Lan S, Liu S, Zhang H
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:612-625
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:612-625
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Yao B, Cai Y, Wan L, Deng J, Zhao L, Wang W, Han Z
The journal of gene medicine 2023 Jun;25(6):e3488
The journal of gene medicine 2023 Jun;25(6):e3488
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
Yang G, Liu X, Jing X, Wang J, Wang H, Chen F, Wang W, Shao Y, Cui X
International immunopharmacology 2023 Jun;119:110159
International immunopharmacology 2023 Jun;119:110159
PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis.
Wang Z, Li R, Hou N, Zhang J, Wang T, Fan P, Ji C, Zhang B, Liu L, Wang Y, Kong J, Yao Q, Duan J, Zhao G, Ling R, Zhang J
Journal for immunotherapy of cancer 2023 Jun;11(6)
Journal for immunotherapy of cancer 2023 Jun;11(6)
Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene.
Cao W, Li Y, Zeng Z, Lei S
Molecules (Basel, Switzerland) 2023 Jun 8;28(12)
Molecules (Basel, Switzerland) 2023 Jun 8;28(12)
Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis.
Yan X, Liu Y, Li C, Mao X, Xu T, Hu Z, Zhang C, Lin N, Lin Y, Zhang Y
Cancer cell international 2023 Jun 6;23(1):109
Cancer cell international 2023 Jun 6;23(1):109
Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway.
Li D, Lu X, Xu G, Liu S, Gong Z, Lu F, Xia X, Jiang J, Wang H, Zou F, Ma X
CNS neuroscience & therapeutics 2023 Jul;29(7):1923-1939
CNS neuroscience & therapeutics 2023 Jul;29(7):1923-1939
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
Ferrostatin-1 alleviates the damage of C2C12 myoblast and mouse pelvic floor muscle induced by mechanical trauma.
He Y, Huang G, Hong S, Zuo X, Zhao Z, Hong L
Cell death discovery 2023 Jul 7;9(1):232
Cell death discovery 2023 Jul 7;9(1):232
The effect of ferroptosis - related proteins and histone deacetylases1 on neoadjuvant chemotherapy in breast cancer.
Sun H, Lin Y, Liu J, Zheng X, Wang Y, Cai J, Wei X
Medicine 2023 Jul 28;102(30):e34444
Medicine 2023 Jul 28;102(30):e34444
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
Zhan S, Liang J, Lin H, Cai J, Yang X, Wu H, Wei J, Wang S, Xian M
Molecular neurobiology 2023 Jan;60(1):413-427
Molecular neurobiology 2023 Jan;60(1):413-427
Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling.
Zhang MW, Li XT, Zhang ZZ, Liu Y, Song JW, Liu XM, Chen YH, Wang N, Guo Y, Liang LR, Zhong JC
Cell stress & chaperones 2023 Jan;28(1):91-103
Cell stress & chaperones 2023 Jan;28(1):91-103
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Xiao S, Zhou Y, Gao H, Yang D
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Fan J, Xu X, Li Y, Zhang L, Miao M, Niu Y, Zhang Y, Zhang A, Jia Z, Wu M
Free radical biology & medicine 2023 Jan;194:84-98
Free radical biology & medicine 2023 Jan;194:84-98
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.
Xing L, Dong W, Chen Y, Dai W, Xiao X, Liu Z, Zhang X, Bai D, Xu H
International immunopharmacology 2023 Jan;114:109607
International immunopharmacology 2023 Jan;114:109607
Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis.
Liu S, Cao X, Zhang T, Zhang C, Qu J, Sun Y, Lv W, Qu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154593
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154593
Dendrobium Nobile Polysaccharides Attenuates Ferroptosis and Improves Cognitive Function in Vascular Dementia Rats.
Ming M, Hu W, Xie G, Chen J, Huang Y
American journal of Alzheimer's disease and other dementias 2023 Jan-Dec;38:15333175231185236
American journal of Alzheimer's disease and other dementias 2023 Jan-Dec;38:15333175231185236
Yiqi Chutan Formula Reverses Cisplatin-Induced Apoptosis and Ferroptosis of Skeletal Muscle by Alleviating Oxidative Stress.
Wu Y, Pi D, Zhou S, Wang W, Ye H, Yi Z, Chen Y, Ouyang M
Integrative cancer therapies 2023 Jan-Dec;22:15347354231172117
Integrative cancer therapies 2023 Jan-Dec;22:15347354231172117
Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.
Cardile A, Zanrè V, Campagnari R, Asson F, Addo SS, Orlandi E, Menegazzi M
International journal of molecular sciences 2023 Jan 9;24(2)
International journal of molecular sciences 2023 Jan 9;24(2)
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cheng L, He Q, Liu B, Chen L, Lv F, Li X, Li Y, Liu C, Song Y, Xing Y
Cell death & disease 2023 Jan 31;14(1):74
Cell death & disease 2023 Jan 31;14(1):74
Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4/xCT signaling pathway.
Zhang J, Wang X, Guan B, Wang X, An X, Wang T, Chen X, Zhao L, Jia J, Song L, Ma D, Li Q, Zhang H, Ju J, Xu H
Journal of ethnopharmacology 2023 Jan 30;301:115852
Journal of ethnopharmacology 2023 Jan 30;301:115852
Berberine hydrochloride alleviates imatinib mesylate - induced cardiotoxicity through the inhibition of Nrf2-dependent ferroptosis.
Song C, Li D, Zhang J, Zhao X
Food & function 2023 Jan 23;14(2):1087-1098
Food & function 2023 Jan 23;14(2):1087-1098
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Jiang Z, Sun H, Miao J, Sheng Q, Xu J, Gao Z, Zhang X, Song Y, Chen K
Biochemical and biophysical research communications 2023 Jan 15;640:183-191
Biochemical and biophysical research communications 2023 Jan 15;640:183-191
Lipocalin 2 induces visual impairment by promoting ferroptosis in retinal ischemia-reperfusion injury.
Mei T, Wu J, Wu K, Zhao M, Luo J, Liu X, Shang B, Xu W, Yang Z, Lai Y, Liu C, Gong H, Gao X, Zhuo Y, Lin M, Zhao L
Annals of translational medicine 2023 Jan 15;11(1):3
Annals of translational medicine 2023 Jan 15;11(1):3
Glutathione ameliorates the meiotic defects of copper exposed ovine oocytes via inhibiting the mitochondrial dysfunctions.
Ren J, Wang B, Li L, Li S, Ma Y, Su L, Liu G, Liu Y, Dai Y
Ecotoxicology and environmental safety 2023 Feb;251:114530
Ecotoxicology and environmental safety 2023 Feb;251:114530
Triterpenoids from Uncaria macrophylla as ferroptosis inhibitors.
Liang X, Wei Y, Hou X, Guo Q, Liang H, Zeng K, Tu P, Zhang Q
Phytochemistry 2023 Feb;206:113530
Phytochemistry 2023 Feb;206:113530
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Tan XH, Gu YY, Song WP, Nan TG, Song WD, Fang D, Yuan YM, Xin ZC, Li XS, Guan RL
Sexual medicine 2023 Feb;11(1):qfac008
Sexual medicine 2023 Feb;11(1):qfac008
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Liang P, Zhang X, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Liu W, Peng B, Yin J, He F, Fan Y, Han S, He X
Free radical biology & medicine 2023 Feb 1;195:329-342
Free radical biology & medicine 2023 Feb 1;195:329-342
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway.
Wang J, Li J, He Y, Huang X, Feng J, Liu L, Liu Y, Jiang X, Jia J
Pulmonary pharmacology & therapeutics 2023 Dec;83:102262
Pulmonary pharmacology & therapeutics 2023 Dec;83:102262
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway.
Sun H, Lu S, Qu G, Li J, Song B
Autoimmunity 2023 Dec;56(1):2290357
Autoimmunity 2023 Dec;56(1):2290357
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
Bu H, Wang B, Wu Y, Li P, Cui Y, Jiang X, Yu X, Liu B, Tang M
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
Xanthohumol attenuates renal ischemia/reperfusion injury by inhibiting ferroptosis.
Tang Z, Feng Y, Nie W, Li C
Experimental and therapeutic medicine 2023 Dec;26(6):571
Experimental and therapeutic medicine 2023 Dec;26(6):571
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Wen W, Xu Y, Qian W, Huang L, Gong J, Li Y, Zhu W, Guo Z
Gut microbes 2023 Dec;15(2):2265578
Gut microbes 2023 Dec;15(2):2265578
Eicosapentaenoic acid enhances the sensitivity of osteosarcoma to cisplatin by inducing ferroptosis through the DNA-PKcs/AKT/NRF2 pathway and reducing PD-L1 expression to attenuate immune evasion.
Zhang Y, Shen G, Meng T, Lv Z, Li X, Li J, Li K
International immunopharmacology 2023 Dec;125(Pt B):111181
International immunopharmacology 2023 Dec;125(Pt B):111181
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.
Zhang Z, Li X, Guo J, He B, Wu L, Yang R, Li X, Fang D, Yang X, Yang D, Wang F, Tang M, Han Y, Jose PA, Wang H, Zeng C
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):164
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):164
Imatinib induces ferroptosis in gastrointestinal stromal tumors by promoting STUB1-mediated GPX4 ubiquitination.
Sun X, Zhang Q, Lin X, Shu P, Gao X, Shen K
Cell death & disease 2023 Dec 18;14(12):839
Cell death & disease 2023 Dec 18;14(12):839
Overexpression of FSP1 Ameliorates ferroptosis via PI3K/ AKT /GSK3β pathway in PC12 cells with Oxygen-Glucose Deprivation/Reoxygenation.
Wu Y, Shi H, Zheng J, Yang Y, Lei X, Qian X, Zhu J
Heliyon 2023 Aug;9(8):e18449
Heliyon 2023 Aug;9(8):e18449
A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease.
Sun Y, Xu L, Zheng D, Wang J, Liu G, Mo Z, Liu C, Zhang W, Yu J, Xing C, He L, Zhuang C
Redox biology 2023 Aug;64:102793
Redox biology 2023 Aug;64:102793
Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure.
Li W, Li W, Li X, Wang L, Wang Y
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1226-1240
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1226-1240
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Li C, He Z, Yao F, Liao S, Sun K, Sun S, Li Z, Wang Z
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Lung 2023 Aug;201(4):425-441
Lung 2023 Aug;201(4):425-441
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Wang X, Quan J, Xiu C, Wang J, Zhang J
Chinese medicine 2023 Aug 30;18(1):110
Chinese medicine 2023 Aug 30;18(1):110
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
MEN1 is a regulator of alternative splicing and prevents R-loop-induced genome instability through suppression of RNA polymerase II elongation.
Jin B, Zhu J, Pan T, Yang Y, Liang L, Zhou Y, Zhang T, Teng Y, Wang Z, Wang X, Tian Q, Guo B, Li H, Chen T
Nucleic acids research 2023 Aug 25;51(15):7951-7971
Nucleic acids research 2023 Aug 25;51(15):7951-7971
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Xue W, Jian W, Meng Y, Wang T, Cai L, Yu Y, Yu Y, Xia Z, Zhang C
Cell death & disease 2023 Aug 21;14(8):539
Cell death & disease 2023 Aug 21;14(8):539
Overexpression of GPX4 attenuates cognitive dysfunction through inhibiting hippocampus ferroptosis and neuroinflammation after traumatic brain injury.
Fang J, Yuan Q, Du Z, Zhang Q, Yang L, Wang M, Yang W, Yuan C, Yu J, Wu G, Hu J
Free radical biology & medicine 2023 Aug 1;204:68-81
Free radical biology & medicine 2023 Aug 1;204:68-81
Targeting the Na(+)/K(+) ATPase DR-region with DR-Ab improves doxorubicin-induced cardiotoxicity.
Leng B, Deng L, Tan J, Lee WT, Cao CR, Wang ZP, Huang DJ, Nie X, Bian JS
Free radical biology & medicine 2023 Aug 1;204:38-53
Free radical biology & medicine 2023 Aug 1;204:38-53
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Qin Y, Bai D, Tang M, Zhang M, Zhao L, Li J, Yang R, Jiang G
Brain research 2023 Aug 1;1812:148404
Brain research 2023 Aug 1;1812:148404
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury.
Kang Y, Zhu R, Li S, Qin KP, Tang H, Shan WS, Yin ZS
Neural regeneration research 2023 Apr;18(4):881-888
Neural regeneration research 2023 Apr;18(4):881-888
Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway.
Jin H, Zhao K, Li J, Xu Z, Liao S, Sun S
International immunopharmacology 2023 Apr;117:109981
International immunopharmacology 2023 Apr;117:109981
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Li J, Lu Q, Peng M, Liao J, Zhang B, Yang D, Huang P, Yang Y, Zhao Q, Han B, Li J
Journal of ethnopharmacology 2023 Apr 6;305:116069
Journal of ethnopharmacology 2023 Apr 6;305:116069
Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway.
Hao J, Chen Q, Feng Y, Jiang Q, Sun H, Deng B, Huang X, Guan J, Chen Q, Liu X, Wang Y, Cao P, Feng F, Li X
Cell death & disease 2023 Apr 6;14(4):247
Cell death & disease 2023 Apr 6;14(4):247
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Wang G, Qin S, Chen L, Geng H, Zheng Y, Xia C, Yao J, Deng L
Cell death & disease 2023 Apr 25;14(4):292
Cell death & disease 2023 Apr 25;14(4):292
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Li Y, Zhang G, Wen F, Xian M, Guo S, Zhang X, Feng X, Hu Z, Hu J
Animals : an open access journal from MDPI 2023 Apr 23;13(9)
Animals : an open access journal from MDPI 2023 Apr 23;13(9)
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Wu Y, Pi D, Zhou S, Yi Z, Dong Y, Wang W, Ye H, Chen Y, Zuo Q, Ouyang M
Acta biochimica et biophysica Sinica 2023 Apr 19;55(4):587-600
Acta biochimica et biophysica Sinica 2023 Apr 19;55(4):587-600
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Qi Y, Hu M, Qiu Y, Zhang L, Yan Y, Feng Y, Feng C, Hou X, Wang Z, Zhang D, Zhao J
Toxicology and applied pharmacology 2023 Apr 15;465:116440
Toxicology and applied pharmacology 2023 Apr 15;465:116440
Ferroptosis mediates decabromodiphenyl ether-induced liver damage and inflammation.
Wang Y, Zhang Y, Xue J, Gao L, Li X, Zhao M, Zhao D, Zhou X
Ecotoxicology and environmental safety 2023 Apr 15;255:114771
Ecotoxicology and environmental safety 2023 Apr 15;255:114771
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Liang Z, Miao Y, Teng X, Xiao L, Guo Q, Xue H, Tian D, Jin S, Wu Y
Frontiers in molecular biosciences 2022;9:947778
Frontiers in molecular biosciences 2022;9:947778
Edaravone Ameliorates Cerebral Ischemia-Reperfusion Injury by Downregulating Ferroptosis via the Nrf2/FPN Pathway in Rats.
Liu W, Wang L, Liu C, Dai Z, Li T, Tang B
Biological & pharmaceutical bulletin 2022;45(9):1269-1275
Biological & pharmaceutical bulletin 2022;45(9):1269-1275
Effect of one-time high load exercise on skeletal muscle injury in rats of different genders: oxidative stress and mitochondrial responses.
Wang Y, Chen M, Gao Y, He K, Yang Z, Li Y, Zhang S, Zhao L
Acta cirurgica brasileira 2022;37(8):e370805
Acta cirurgica brasileira 2022;37(8):e370805
Attenuation by Time-Restricted Feeding of High-Fat and High-Fructose Diet-Induced NASH in Mice Is Related to Per2 and Ferroptosis.
Shu YY, Gao WK, Chu HK, Yang L, Pan XL, Ye J
Oxidative medicine and cellular longevity 2022;2022:8063897
Oxidative medicine and cellular longevity 2022;2022:8063897
Cryptotanshinone Protects against PCOS-Induced Damage of Ovarian Tissue via Regulating Oxidative Stress, Mitochondrial Membrane Potential, Inflammation, and Apoptosis via Regulating Ferroptosis.
Liu H, Xie J, Fan L, Xia Y, Peng X, Zhou J, Ni X
Oxidative medicine and cellular longevity 2022;2022:8011850
Oxidative medicine and cellular longevity 2022;2022:8011850
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
Gong H, Gao M, Lin Y, Liu J, Hu Z, Liu J
Oxidative medicine and cellular longevity 2022;2022:7843863
Oxidative medicine and cellular longevity 2022;2022:7843863
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
Li X, Wu L, Tian X, Zheng W, Yuan M, Tian X, Zuo H, Song H, Shen Z
Oxidative medicine and cellular longevity 2022;2022:6520789
Oxidative medicine and cellular longevity 2022;2022:6520789
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Zhang J, Liu Z, Dong Y
Disease markers 2022;2022:6423237
Disease markers 2022;2022:6423237
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Wu Y, Pi D, Chen Y, Zuo Q, Zhou S, Ouyang M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6177553
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6177553
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Peng Y, Liao B, Zhou Y, Zeng W, Zeng ZY
Cardiology research and practice 2022;2022:3972829
Cardiology research and practice 2022;2022:3972829
SLC7A11/GPX4 Inactivation-Mediated Ferroptosis Contributes to the Pathogenesis of Triptolide-Induced Cardiotoxicity.
Liu X, Chen C, Han D, Zhou W, Cui Y, Tang X, Xiao C, Wang Y, Gao Y
Oxidative medicine and cellular longevity 2022;2022:3192607
Oxidative medicine and cellular longevity 2022;2022:3192607
Artemether attenuates renal tubular injury by regulating iron metabolism in mice with streptozotocin-induced diabetes.
Rong G, Cai Y, Weng W, Chen Y, Yu X, Shao M, Han P, Sun H
American journal of translational research 2022;14(9):6095-6106
American journal of translational research 2022;14(9):6095-6106
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Shao Y, Sun L, Yang G, Wang W, Liu X, Du T, Chen F, Jing X, Cui X
Frontiers in pharmacology 2022;13:937502
Frontiers in pharmacology 2022;13:937502
Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity.
Jiang JJ, Zhang GF, Zheng JY, Sun JH, Ding SB
Frontiers in pharmacology 2022;13:876550
Frontiers in pharmacology 2022;13:876550
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Kang X, Huo Y, Jia S, He F, Li H, Zhou Q, Chang N, Liu D, Li R, Hu Y, Zhang P, Xu A
Frontiers in oncology 2022;12:939605
Frontiers in oncology 2022;12:939605
Glutathione Peroxidase 4 as a Therapeutic Target for Anti-Colorectal Cancer Drug-Tolerant Persister Cells.
Zhang X, Ma Y, Ma J, Yang L, Song Q, Wang H, Lv G
Frontiers in oncology 2022;12:913669
Frontiers in oncology 2022;12:913669
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Li X, Yu Q, Zhao R, Guo X, Liu C, Zhang K, Zhang W, Liu J, Yu J, Wang S, Hao Q, Li W, Zhang W, Li M, Zhang Y, Zhang C, Gao Y
Frontiers in oncology 2022;12:898156
Frontiers in oncology 2022;12:898156
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Liu H, Zhao L, Wang M, Yang K, Jin Z, Zhao C, Shi G
Frontiers in oncology 2022;12:852095
Frontiers in oncology 2022;12:852095
PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics.
Wang Y, Song H, Miao Q, Wang Y, Qi J, Xu X, Sun J
Frontiers in oncology 2022;12:819235
Frontiers in oncology 2022;12:819235
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Li J, Tang X, Tu X, Jin Z, Dong H, Yang Q, Yao T, Pan Z
Cell stress & chaperones 2022 Sep;27(5):485-497
Cell stress & chaperones 2022 Sep;27(5):485-497
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Wang W, Jing X, Du T, Ren J, Liu X, Chen F, Shao Y, Sun S, Yang G, Cui X
Free radical biology & medicine 2022 Sep;190:234-246
Free radical biology & medicine 2022 Sep;190:234-246
Hedyotis diffusa injection induces ferroptosis via the Bax/Bcl2/VDAC2/3 axis in lung adenocarcinoma.
Huang F, Pang J, Xu L, Niu W, Zhang Y, Li S, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154319
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154319
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Liu MJ, Zhao XC, Gong HS, You YQ, Li JY
Neuroscience letters 2022 Sep 25;788:136842
Neuroscience letters 2022 Sep 25;788:136842
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Li Y, Zhang E, Yang H, Chen Y, Tao L, Xu Y, Chen T, Shen X
Molecules (Basel, Switzerland) 2022 Sep 24;27(19)
Molecules (Basel, Switzerland) 2022 Sep 24;27(19)
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Li B, Wang C, Lu P, Ji Y, Wang X, Liu C, Lu X, Xu X, Wang X
Biology 2022 Sep 23;11(10)
Biology 2022 Sep 23;11(10)
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury.
Ye J, Peng J, Liu K, Zhang T, Huang W
American journal of physiology. Gastrointestinal and liver physiology 2022 Sep 1;323(3):G283-G293
American journal of physiology. Gastrointestinal and liver physiology 2022 Sep 1;323(3):G283-G293
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Feng W, Xiao Y, Zhao C, Zhang Z, Liu W, Ma J, Ganz T, Zhang J, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2202679
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2202679
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins.
Miller CE, Xu F, Zhao Y, Luo W, Zhong W, Meyer K, Jayswal R, Weiss HL, St Clair WH, St Clair DK, Chaiswing L
Antioxidants (Basel, Switzerland) 2022 Oct 27;11(11)
Antioxidants (Basel, Switzerland) 2022 Oct 27;11(11)
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma.
Wang S, Chen L, Liu W
Cancer cell international 2022 Oct 13;22(1):318
Cancer cell international 2022 Oct 13;22(1):318
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Huang R, Zhang C, Wang X, Zou X, Xiang Z, Wang Z, Gui B, Lin T, Hu H
Cancer medicine 2022 Nov;11(21):3993-4004
Cancer medicine 2022 Nov;11(21):3993-4004
Cadmium induces ferroptosis mediated inflammation by activating Gpx4/Ager/p65 axis in pancreatic β-cells.
Hong H, Lin X, Xu Y, Tong T, Zhang J, He H, Yang L, Lu Y, Zhou Z
The Science of the total environment 2022 Nov 25;849:157819
The Science of the total environment 2022 Nov 25;849:157819
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Li XT, Song JW, Zhang ZZ, Zhang MW, Liang LR, Miao R, Liu Y, Chen YH, Liu XY, Zhong JC
Free radical biology & medicine 2022 Nov 20;193(Pt 1):459-473
Free radical biology & medicine 2022 Nov 20;193(Pt 1):459-473
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Wang J, Wen J, Ma X, Yang J, Zhang Z, Xie S, Wei S, Jing M, Li H, Lang L, Zhou X, Zhao Y
European journal of pharmacology 2022 Nov 15;935:175331
European journal of pharmacology 2022 Nov 15;935:175331
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
Guo J, Cheng M, Liu P, Cao D, Luo J, Wan Y, Fang Y, Jin Y, Xie SS, Liu J
European journal of medicinal chemistry 2022 Nov 15;242:114630
European journal of medicinal chemistry 2022 Nov 15;242:114630
Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance.
Zhang C, Wang C, Yang Z, Bai Y, Shukuya T, Poh ME, Ekman S, Li J, Xu Y, Deng S
Translational lung cancer research 2022 May;11(5):786-801
Translational lung cancer research 2022 May;11(5):786-801
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
Li J, Li M, Ge Y, Chen J, Ma J, Wang C, Sun M, Wang L, Yao S, Yao C
Cell & bioscience 2022 May 26;12(1):69
Cell & bioscience 2022 May 26;12(1):69
Ferritinophagy is Involved in Experimental Subarachnoid Hemorrhage-Induced Neuronal Ferroptosis.
Liang Y, Deng Y, Zhao J, Liu L, Wang J, Chen P, Zhang Q, Sun C, Wang Y, Xiang Y, He Z
Neurochemical research 2022 Mar;47(3):692-700
Neurochemical research 2022 Mar;47(3):692-700
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.
Zhang Z, Tang J, Song J, Xie M, Liu Y, Dong Z, Liu X, Li X, Zhang M, Chen Y, Shi H, Zhong J
Free radical biology & medicine 2022 Mar;181:130-142
Free radical biology & medicine 2022 Mar;181:130-142
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Li J, Deng SH, Li J, Li L, Zhang F, Zou Y, Wu DM, Xu Y
Cellular & molecular biology letters 2022 Mar 19;27(1):29
Cellular & molecular biology letters 2022 Mar 19;27(1):29
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Wu WY, Wang ZX, Li TS, Ding XQ, Liu ZH, Yang J, Fang L, Kong LD
Redox biology 2022 Jun;52:102303
Redox biology 2022 Jun;52:102303
Notch3 regulates ferroptosis via ROS-induced lipid peroxidation in NSCLC cells.
Li Z, Xiao J, Liu M, Cui J, Lian B, Sun Y, Li C
FEBS open bio 2022 Jun;12(6):1197-1205
FEBS open bio 2022 Jun;12(6):1197-1205
Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis.
Yan J, Feng G, Ma L, Chen Z, Jin Q
Journal of orthopaedic surgery and research 2022 Jun 28;17(1):333
Journal of orthopaedic surgery and research 2022 Jun 28;17(1):333
Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats.
Huang Y, Wu H, Hu Y, Zhou C, Wu J, Wu Y, Wang H, Lenahan C, Huang L, Nie S, Gao X, Sun J
Antioxidants (Basel, Switzerland) 2022 Jun 27;11(7)
Antioxidants (Basel, Switzerland) 2022 Jun 27;11(7)
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
Zhang Y, Zhang C, Li J, Jiang M, Guo S, Yang G, Zhang L, Wang F, Yi S, Wang J, Fu Y, Zhang Y
Cell communication and signaling : CCS 2022 Jun 17;20(1):93
Cell communication and signaling : CCS 2022 Jun 17;20(1):93
Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation.
Meng Q, Xu Y, Ling X, Liu H, Ding S, Wu H, Yan D, Fang X, Li T, Liu Q
BMC cardiovascular disorders 2022 Jul 29;22(1):339
BMC cardiovascular disorders 2022 Jul 29;22(1):339
Seco-Lupane Triterpene Derivatives Induce Ferroptosis through GPX4/ACSL4 Axis and Target Cyclin D1 to Block the Cell Cycle.
Wang H, Wu D, Gao C, Teng H, Zhao Y, He Z, Chen W, Zong Y, Du R
Journal of medicinal chemistry 2022 Jul 28;65(14):10014-10044
Journal of medicinal chemistry 2022 Jul 28;65(14):10014-10044
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Yi L, Hu Y, Wu Z, Li Y, Kong M, Kang Z, Zuoyuan B, Yang Z
Cell death & disease 2022 Jul 11;13(7):592
Cell death & disease 2022 Jul 11;13(7):592
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Cui Z, Wang H, Li S, Qin T, Shi H, Ma J, Li L, Yu G, Jiang T, Li C
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Zhang P, Zhang J, Quan H, Chen P, Wang J, Liang Y
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Insamgobonhwan Protects Neuronal Cells from Lipid ROS and Improves Deficient Cognitive Function.
Yang JH, Nguyen CD, Lee G, Na CS
Antioxidants (Basel, Switzerland) 2022 Jan 31;11(2)
Antioxidants (Basel, Switzerland) 2022 Jan 31;11(2)
A biomimetic nanodrug self-assembled from small molecules for enhanced ferroptosis therapy.
Xu X, Chen Y, Gui J, Liu P, Huang Y, Shao B, Ping Y, Li B
Biomaterials science 2022 Feb 1;10(3):770-780
Biomaterials science 2022 Feb 1;10(3):770-780
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
Li X, Chu Y, Ma R, Dou M, Li S, Song Y, Lv Y, Zhu L
Journal of neuroimmunology 2022 Dec 15;373:577995
Journal of neuroimmunology 2022 Dec 15;373:577995
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
Bao C, Liu C, Liu Q, Hua L, Hu J, Li Z, Xu S
International immunopharmacology 2022 Aug;109:108770
International immunopharmacology 2022 Aug;109:108770
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
Comprehensive analysis of placental gene-expression profiles and identification of EGFR-mediated autophagy and ferroptosis suppression in intrahepatic cholestasis of pregnancy.
Fang Y, Fang D
Gene 2022 Aug 5;834:146594
Gene 2022 Aug 5;834:146594
Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis.
Zhang Z, Ji C, Wang YN, Liu S, Wang M, Xu X, Zhang D
Cells 2022 Aug 17;11(16)
Cells 2022 Aug 17;11(16)
GPX4 suppresses ferroptosis to promote malignant progression of endometrial carcinoma via transcriptional activation by ELK1.
Wei S, Yu Z, Shi R, An L, Zhang Q, Zhang Q, Zhang T, Zhang J, Wang H
BMC cancer 2022 Aug 12;22(1):881
BMC cancer 2022 Aug 12;22(1):881
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
Wang P, Zhang S, Lin S, Lv Z
Reproductive biology and endocrinology : RB&E 2022 Aug 12;20(1):117
Reproductive biology and endocrinology : RB&E 2022 Aug 12;20(1):117
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Chang MT, Tsai LC, Nakagawa-Goto K, Lee KH, Shyur LF
Pharmacological research 2022 Apr;178:106148
Pharmacological research 2022 Apr;178:106148
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Sun F, Zhou JL, Liu ZL, Jiang ZW, Peng H
Biochemical and biophysical research communications 2022 Apr 30;602:149-155
Biochemical and biophysical research communications 2022 Apr 30;602:149-155
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Liang Z, Wu Q, Wang H, Tan J, Wang H, Gou Y, Cao Y, Li Z, Zhang Z
Cell death discovery 2022 Apr 11;8(1):190
Cell death discovery 2022 Apr 11;8(1):190
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Li L, Li H, Li Y, Feng J, Guan D, Zhang Y, Fu Y, Li S, Li C
Oxidative medicine and cellular longevity 2021;2021:5594059
Oxidative medicine and cellular longevity 2021;2021:5594059
Ferritinophagic Flux Was a Driving Force in Determination of Status of EMT, Ferroptosis, and NDRG1 Activation in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate S-Acetic Acid.
Li H, Zhou W, Wei H, Li L, Wang X, Li Y, Li S, Li C
Journal of oncology 2021;2021:3015710
Journal of oncology 2021;2021:3015710
Calorie Restriction Protects against Contrast-Induced Nephropathy via SIRT1/GPX4 Activation.
Fang D, Wang Y, Zhang Z, Yang D, Gu D, He B, Zhang X, He D, Wang H, Jose PA, Han Y, Zeng C
Oxidative medicine and cellular longevity 2021;2021:2999296
Oxidative medicine and cellular longevity 2021;2021:2999296
Mesenchymal Stem Cells Alleviate Post-resuscitation Cardiac and Cerebral Injuries by Inhibiting Cell Pyroptosis and Ferroptosis in a Swine Model of Cardiac Arrest.
Xu J, Zhang M, Liu F, Shi L, Jiang X, Chen C, Wang J, Diao M, Khan ZU, Zhang M
Frontiers in pharmacology 2021;12:793829
Frontiers in pharmacology 2021;12:793829
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Chen L, Niu X, Qiao X, Liu S, Ma H, Shi X, He X, Zhong M
Frontiers in immunology 2021;12:739039
Frontiers in immunology 2021;12:739039
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Li W, Li W, Wang Y, Leng Y, Xia Z
Cell death discovery 2021 Sep 29;7(1):267
Cell death discovery 2021 Sep 29;7(1):267
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Tian H, Xiong Y, Zhang Y, Leng Y, Tao J, Li L, Qiu Z, Xia Z
Cell stress & chaperones 2021 Mar;27(2):149-164
Cell stress & chaperones 2021 Mar;27(2):149-164
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
Wei N, Lu T, Yang L, Dong Y, Liu X
FEBS open bio 2021 Aug;11(8):2118-2126
FEBS open bio 2021 Aug;11(8):2118-2126
Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway.
Hu X, Luo J, Lai H, Li M, Zheng X, Nie T, Li F, Li H
Biochemical and biophysical research communications 2018 Sep 5;503(2):521-527
Biochemical and biophysical research communications 2018 Sep 5;503(2):521-527
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