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- References [172]
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- Product number
- 14432-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14432-1-AP, RRID:AB_10898356
- Product name
- GPX4 antibody
- Antibody type
- Polyclonal
- Description
- GPX4 antibody (Cat. #14432-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ferroptosis as a novel alternative cell death model in Hashimoto´s thyroiditis.
DEAF1 confers resistance to adriamycin-induced apoptosis and pyroptosis in multiple myeloma.
GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Nanoplastic PS and cadmium co-exposure accelerates ferroptosis mediated by HIF-1α-related signaling in spermatogonium.
Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy.
Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.
Unusual chaetoglobosins and a new type of ferroptosis inducer from an endophytic fungus Chaetomium sp. UJN-EF006.
ZIP8 modulates ferroptosis to drive esophageal carcinoma progression.
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.
Erythrocyte Membrane-Camouflaged Xanthohumol Nanoparticles Mitigate Doxorubicin-Induced Cardiotoxicity by Inhibiting Ferroptosis.
Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1.
TRPV4 as a Novel Regulator of Ferroptosis in Colon Adenocarcinoma: Implications for Prognosis and Therapeutic Targeting.
Multienzyme-like polyoxometalate for oxygen-independent sonocatalytic enhanced cancer therapy.
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis.
Smilax glabra Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer.
A novel KEAP1 inhibitor, tiliroside, activates NRF2 to protect against acetaminophen-induced oxidative stress and acute liver injury.
The IGF2BP2-circ-DAPK1 axis promotes high-glucose-induced ferroptosis of HUVECs by decreasing NQO1 expression.
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Chronic exposure to polyethylene terephthalate microplastics induces gut microbiota dysbiosis and disordered hepatic lipid metabolism in mice.
Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Novel ultrathin ferrous sulfide nanosheets: Towards replacing black phosphorus in anticancer nanotheranostics.
Role of miRNA regulation in IGFBP-2 overexpression and neuronal ferroptosis: Insights into the Nrf2/SLC7A11/GPX4 pathway in Alzheimer's disease.
A metal-organic framework functionalized CaO(2)-based cascade nanoreactor induces synergistic cuproptosis/ferroptosis and Ca(2+) overload-mediated mitochondrial damage for enhanced sono-chemodynamic immunotherapy.
Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis.
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
SPI1 Regulates Autophagy by Promoting ATG7 Transcription to Enhance Ferroptosis in Myocardial Ischemia/Reperfusion Injury.
Liensinine can improve vascular remodeling in hypertension through the ferroptosis-related TLR4 inflammatory pathway.
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
Albumin nanoassembly bi-directionally manipulated ferroptosis in tumor and CD8(+) T cells for triple-negative breast cancer therapy.
GNF-5837 attenuates acute liver injury by inhibiting oxidative stress.
Synchronously Evoking Disulfidptosis and Ferroptosis via Systematical Glucose Deprivation Targeting SLC7A11/GSH/GPX4 Antioxidant Axis.
Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance.
Circular RNA ANKIB1 alleviates hypoxia-induced cardiomyocyte injury by modulating miR-452-5p/SLC7A11 axis.
The role of hepatitis B virus surface protein in inducing Sertoli cell ferroptosis.
Ferroptosis in Osteocytes as a Target for Protection Against Postmenopausal Osteoporosis.
Glycyrrhizic acid attenuates sorafenib resistance by inducing ferroptosis via targeting mTOR signaling in hepatocellular carcinoma.
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Astragalus Polysaccharides and Metformin May Have Synergistic Effects on the Apoptosis and Ferroptosis of Lung Adenocarcinoma A549 Cells.
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Polyphyllin I induced ferroptosis to suppress the progression of hepatocellular carcinoma through activation of the mitochondrial dysfunction via Nrf2/HO-1/GPX4 axis.
Inhibition of Apoc1 reverses resistance of sorafenib by promoting ferroptosis in esophageal cancers.
Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury.
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
NIR-Actuated Ferroptosis Nanomotor for Enhanced Tumor Penetration and Therapy.
Lif-deficiency promote systemic Iron metabolism disorders and increases the susceptibility of osteoblasts to ferroptosis.
REV-ERBα inhibitor rescues MPTP/MPP(+)-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway.
CCT3/ACTN4/TFRC axis protects hepatocellular carcinoma cells from ferroptosis by inhibiting iron endocytosis.
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Vitamin D Promotes Ferroptosis in Colorectal Cancer Stem Cells via SLC7A11 Downregulation.
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity by targeting mitochondrial ROS-mediated ferroptosis.
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis.
Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis.
Tumor microenvironment-initiated lipid redox cycling for efficient triple-negative breast cancer therapy.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosis.
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.
Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications.
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration.
AMPK activation alleviated dextran sulfate sodium-induced colitis by inhibiting ferroptosis.
Identification of a ferroptosis-related gene signature for prognosis prediction in colorectal cancer patients and relationship with vitamin D.
Evodiamine Exhibits Anti-Bladder Cancer Activity by Suppression of Glutathione Peroxidase 4 and Induction of Ferroptosis.
Homocysteine induces ferroptosis in endothelial cells through the systemXc(-)/GPX4 signaling pathway.
Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing.
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
TRIM59 promotes steatosis and ferroptosis in non-alcoholic fatty liver disease via enhancing GPX4 ubiquitination.
Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis.
Increased expression of GPX4 promotes the tumorigenesis of thyroid cancer by inhibiting ferroptosis and predicts poor clinical outcomes.
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
pH-sensitive molybdenum (Mo)-based polyoxometalate nanoclusters have therapeutic efficacy in inflammatory bowel disease by counteracting ferroptosis.
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
Thermoresponsive Ozone-Enriched Spray Gel for Postsurgical Treatment of Hepatocellular Carcinoma.
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation.
Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway.
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Role of GPX4 inhibition-mediated ferroptosis in the chemoresistance of ovarian cancer to Taxol in vitro.
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
PS-MPs or their co-exposure with cadmium impair male reproductive function through the miR-199a-5p/HIF-1α-mediated ferroptosis pathway.
HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1.
Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway.
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
The Effects of Alda-1 Treatment on Renal and Intestinal Injuries After Cardiopulmonary Resuscitation in Pigs.
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Activated Stellate Cell Paracrine HGF Exacerbated Pancreatic Cancer Cell Ferroptosis Resistance.
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Pyrocatechol Alleviates Cisplatin-Induced Acute Kidney Injury by Inhibiting ROS Production.
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Probiotic Saccharomyces boulardii attenuates cardiopulmonary bypass-induced acute lung injury by inhibiting ferroptosis.
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage.
Naringin Relieves Diabetic Cardiac Autonomic Neuropathy Mediated by P2Y(14) Receptor in Superior Cervical Ganglion.
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes.
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
The Clock gene regulates kainic acid-induced seizures through inhibiting ferroptosis in mice.
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2/HO-1 pathway.
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancerthrough inhibiting GPX4 and enhancing ROS.
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy.
A Multifunctional Vanadium-Iron-Oxide Nanoparticle Eradicates Hepatocellular Carcinoma via Targeting Tumor and Endothelial Cells.
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM(2.5).
Ferroptosis, as the most enriched programmed cell death process in glioma, induces immunosuppression and immunotherapy resistance.
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Low Sulfur Amino Acid, High Polyunsaturated Fatty Acid Diet Inhibits Breast Cancer Growth.
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Ulinastatin protects against acetaminophen-induced liver injury by alleviating ferroptosis via the SIRT1/NRF2/HO-1 pathway.
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia.
Proteome Analysis of Camellia nitidissima Chi Revealed Its Role in Colon Cancer Through the Apoptosis and Ferroptosis Pathway.
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice.
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
Novel function of fluvastatin in attenuating oxidized low-density lipoprotein-induced endothelial cell ferroptosis in a glutathione peroxidase4- and cystine-glutamate antiporter-dependent manner.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Combination of ponatinib with deferoxamine synergistically mitigates ischemic heart injury via simultaneous prevention of necroptosis and ferroptosis.
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
Dihydroisotanshinone I induced ferroptosis and apoptosis of lung cancer cells.
SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18.
Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs.
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis.
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis.
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer.
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Fasting Drives Nrf2-Related Antioxidant Response in Skeletal Muscle.
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Danshen Improves Survival of Patients With Breast Cancer and Dihydroisotanshinone I Induces Ferroptosis and Apoptosis of Breast Cancer Cells.
Role of ferroptosis in the process of acute radiation-induced lung injury in mice.
Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice.
Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.
Effects of autophagy on the spermatogonia of chronic hypoxic mice.
Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development.
Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice.
Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.
Alteration of sperm protein profile induced by cigarette smoking.
Sacristán-Gómez P, Delgado-Martín S, Serrano-Somavilla A, Sánchez de la Blanca N, Sampedro-Nuñez M, Sebastian-Valles F, Martínez-Ruiz A, Marazuela M, Martínez-Hernández R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 May;198:119276
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 May;198:119276
DEAF1 confers resistance to adriamycin-induced apoptosis and pyroptosis in multiple myeloma.
Deng Z, Wei Y, Liu S, Chen L, Wang X, Liu Z, Liu L, Wang Y, Lv X, Sun S, Ni H, Gu C, Yang Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Mar;85:101344
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Mar;85:101344
GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.
Chen Z, Ho IL, Liu J, Soeung M, Yen EY, Sainani S, Dyke CA, Shah R, Kwon HJ, Han G, Yan X, Zhang S, Srinivasan S, Rose JL, Citron F, Jiang S, Chang Q, Feng N, Genovese G, Gao S, Yao W, Wang L, Wang H, Ying H, Viale A, Draetta GF
Cancer research 2026 Mar 2;86(5):1132-1147
Cancer research 2026 Mar 2;86(5):1132-1147
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Zhan Y, Zhang Z, Zhang Z, Lin M, Liu H, Abulimiti D, Aihemaiti S, Kan Y, Tan J, Chen X, Tao S
Journal of nanobiotechnology 2026 Mar 17;24(1)
Journal of nanobiotechnology 2026 Mar 17;24(1)
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Wang W, Li Z, Lyu C, Wang T, Han C, Cui S, Wang J, Xu R
International journal of nanomedicine 2025;20:4035-4050
International journal of nanomedicine 2025;20:4035-4050
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Chu G, Wang J, Wang Z, Cai X, Shi S, Qing Q, Zhong Y, Zhang Q
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Nanoplastic PS and cadmium co-exposure accelerates ferroptosis mediated by HIF-1α-related signaling in spermatogonium.
Zhang Q, Guo P, Zhou X, Yang C, Lu Z, Wu S, Lu X, Yang J, Jin C
Free radical biology & medicine 2025 Sep;237:11-20
Free radical biology & medicine 2025 Sep;237:11-20
Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy.
Cai W, Sun Y, Xu W, Kuang X, Zhang Z, Cao X, Xu J, Li Y, Huang Y, Shen S
ACS nano 2025 Sep 16;19(36):32405-32421
ACS nano 2025 Sep 16;19(36):32405-32421
Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.
Feng J, Miao H, Xiao Z, Xu L, Wang Y, Cao X, Wang J, Wu Z, Xia P, Liu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157113
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157113
Unusual chaetoglobosins and a new type of ferroptosis inducer from an endophytic fungus Chaetomium sp. UJN-EF006.
Wang YY, Wang YS, Li JJ, Wan ZY, Zhang H
Bioorganic chemistry 2025 May;158:108342
Bioorganic chemistry 2025 May;158:108342
ZIP8 modulates ferroptosis to drive esophageal carcinoma progression.
Yang Z, Zhao K, Li X, Yanzhang R, Zhang H, Yu Y, Yan M, Fang S, Li T, Li H, Chu X, Han S, Zhang Z, Teng J, Jin G, Guo Z
Cell death & disease 2025 May 6;16(1):366
Cell death & disease 2025 May 6;16(1):366
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.
Zhang X, Deng Z, Zhang X, Xu Q, Liu L, Yang D, Guo Z
European journal of medical research 2025 May 20;30(1):403
European journal of medical research 2025 May 20;30(1):403
Erythrocyte Membrane-Camouflaged Xanthohumol Nanoparticles Mitigate Doxorubicin-Induced Cardiotoxicity by Inhibiting Ferroptosis.
Li J, Zeng Y, Liu F, Liao X, Zhong C, Dong S, Cai Y, Yang P
ACS biomaterials science & engineering 2025 May 12;11(5):2727-2738
ACS biomaterials science & engineering 2025 May 12;11(5):2727-2738
Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1.
Zhou H, Zhou J, Liu S, Niu J, Pan J, Li R
Redox biology 2025 Mar;80:103508
Redox biology 2025 Mar;80:103508
TRPV4 as a Novel Regulator of Ferroptosis in Colon Adenocarcinoma: Implications for Prognosis and Therapeutic Targeting.
Ren X, Chen W, Liu Y, Chen Z, Wang X, Sun X
Digestive diseases and sciences 2025 Mar;70(3):1064-1077
Digestive diseases and sciences 2025 Mar;70(3):1064-1077
Multienzyme-like polyoxometalate for oxygen-independent sonocatalytic enhanced cancer therapy.
Yang H, Li X, Wang Q, Yang F, Zhong X, Gu L, Miao Y, Liu B, Li Y
Journal of colloid and interface science 2025 Mar;681:319-330
Journal of colloid and interface science 2025 Mar;681:319-330
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Peng X, Yang R, Wang C, Peng W, Zhao Z, Shi S, Cai Q, He B, Wang L, Yu F, Wang X, Tao Y
Cancer letters 2025 Mar 31;613:217503
Cancer letters 2025 Mar 31;613:217503
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis.
Pan Z, Gan C, Zhi S, Yang Y, Zhang Y, Li L, Zhang S, Huang Q
Journal of ethnopharmacology 2025 Mar 26;344:119532
Journal of ethnopharmacology 2025 Mar 26;344:119532
Smilax glabra Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer.
Xu J, Cai Z, Pang Z, Chen J, Zhu K, Wang D, Tu J
International journal of molecular sciences 2025 Mar 10;26(6)
International journal of molecular sciences 2025 Mar 10;26(6)
A novel KEAP1 inhibitor, tiliroside, activates NRF2 to protect against acetaminophen-induced oxidative stress and acute liver injury.
Cai F, Zhou K, Wang P, Zhang W, Liu L, Yang Y
Hepatology communications 2025 Mar 1;9(3)
Hepatology communications 2025 Mar 1;9(3)
The IGF2BP2-circ-DAPK1 axis promotes high-glucose-induced ferroptosis of HUVECs by decreasing NQO1 expression.
Qiu C, Zheng X, Zhou X, Wang B, Chen T, Xu Y, Yu X, Lu W, Wu Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167797
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167797
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Zhang J, Tan B, Wu H, Han T, Fang D, Cai H, Hu B, Kang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Chronic exposure to polyethylene terephthalate microplastics induces gut microbiota dysbiosis and disordered hepatic lipid metabolism in mice.
Lu T, Liu H, Yuan X, Li D, Zhang G, Wang Y, Xie Q, Wang X, Chi J, Wang Z, Wang S, Gao Y, Zhou L, Xu M
Ecotoxicology and environmental safety 2025 Jun 15;298:118330
Ecotoxicology and environmental safety 2025 Jun 15;298:118330
Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.
Liu Z, Ye J, Xi J, Li Q, Tang Y, Tian Y, Wang D, Yang Z, Ding Y
Food science & nutrition 2025 Jul;13(7):e70589
Food science & nutrition 2025 Jul;13(7):e70589
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Wang S, Zhu L, Wang Y, Han Y, Wang Q, Yang W, Zhao L, Zhang Y, Pei D, Huang W, Jin A, Lin Z, Piao J
Cell death & disease 2025 Jul 23;16(1):549
Cell death & disease 2025 Jul 23;16(1):549
Novel ultrathin ferrous sulfide nanosheets: Towards replacing black phosphorus in anticancer nanotheranostics.
Gao Y, Mu M, Wei Y, Yan B, Liu H, Guo K, Zhang M, Dai X, Sun X, Leong DT
Bioactive materials 2025 Jan;43:564-578
Bioactive materials 2025 Jan;43:564-578
Role of miRNA regulation in IGFBP-2 overexpression and neuronal ferroptosis: Insights into the Nrf2/SLC7A11/GPX4 pathway in Alzheimer's disease.
Luo C, Wu G, Xiao Z, Hu R, Qiao M, Li W, Liu C, Li Z, Lan C, Huang Z
International journal of biological macromolecules 2025 Jan;287:138537
International journal of biological macromolecules 2025 Jan;287:138537
A metal-organic framework functionalized CaO(2)-based cascade nanoreactor induces synergistic cuproptosis/ferroptosis and Ca(2+) overload-mediated mitochondrial damage for enhanced sono-chemodynamic immunotherapy.
Tang C, Liu K, Gao X, Kang H, Xie W, Chang J, Yin L, Kang J
Acta biomaterialia 2025 Jan 24;193:455-473
Acta biomaterialia 2025 Jan 24;193:455-473
Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis.
Huang B, Wang H, Liu S, Hao M, Luo D, Zhou Y, Huang Y, Nian Y, Zhang L, Chu B, Yin C
Nature communications 2025 Jan 20;16(1):867
Nature communications 2025 Jan 20;16(1):867
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
Fan Y, Ren Y, Deng L, Lv D, Chen J, Ling Y, Tu J, Xu X, Wang D, Cai Z
International immunopharmacology 2025 Jan 10;144:113641
International immunopharmacology 2025 Jan 10;144:113641
SPI1 Regulates Autophagy by Promoting ATG7 Transcription to Enhance Ferroptosis in Myocardial Ischemia/Reperfusion Injury.
Li WL, Han X, Pan WL, Wang H, You DL, Chen XT, Wu X, Jin MM, Wang F
Journal of cellular biochemistry 2025 Dec;126(12):e70078
Journal of cellular biochemistry 2025 Dec;126(12):e70078
Liensinine can improve vascular remodeling in hypertension through the ferroptosis-related TLR4 inflammatory pathway.
Chen D, Jia P, Wang M, Du B, Du H, Huang X, Zeng J, Cai Q, Zhang L, Zhu Y, Lin S, Lian D, Peng J
Journal of molecular medicine (Berlin, Germany) 2025 Dec 26;104(1):13
Journal of molecular medicine (Berlin, Germany) 2025 Dec 26;104(1):13
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
Liang Z, Liu J, Gou Y, Wang H, Li Z, Cao Y, Zhang H, Bai R, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
Albumin nanoassembly bi-directionally manipulated ferroptosis in tumor and CD8(+) T cells for triple-negative breast cancer therapy.
Yang T, Liu Z, Fu Z, Zhang X, Cao Y, Liang Q, Miao J, Yang H, Zhang T, Hei J, Ni W, Liu Y
Asian journal of pharmaceutical sciences 2025 Apr;20(2):100970
Asian journal of pharmaceutical sciences 2025 Apr;20(2):100970
GNF-5837 attenuates acute liver injury by inhibiting oxidative stress.
Zhou X, Luo X, Huang Q, Ru Y, Liu D, Linghu M, Huang Y
Molecular biology reports 2025 Apr 21;52(1):407
Molecular biology reports 2025 Apr 21;52(1):407
Synchronously Evoking Disulfidptosis and Ferroptosis via Systematical Glucose Deprivation Targeting SLC7A11/GSH/GPX4 Antioxidant Axis.
Zhang M, Zheng H, Zhu X, Liu S, Jin H, Chen Y, Wan L, Zhang S, Zhang H
ACS nano 2025 Apr 15;19(14):14233-14248
ACS nano 2025 Apr 15;19(14):14233-14248
Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance.
Lin X, Zhang Q, Li Q, Deng J, Shen S, Tang M, Ye X, Ji C, Yang Y, Chen Y, Zeng L, Zhao J, Kouwenhoven MBN, Lucero-Prisno DE 3rd, Huang J, Li Y, Zhang B, Hu J
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101032
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101032
Circular RNA ANKIB1 alleviates hypoxia-induced cardiomyocyte injury by modulating miR-452-5p/SLC7A11 axis.
Li G, Tang X, Tang H
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Mar;33(3):261-272
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Mar;33(3):261-272
The role of hepatitis B virus surface protein in inducing Sertoli cell ferroptosis.
Pan C, Kong X, Wu Z, Fei Q
Andrology 2024 Mar;12(3):643-654
Andrology 2024 Mar;12(3):643-654
Ferroptosis in Osteocytes as a Target for Protection Against Postmenopausal Osteoporosis.
Jiang Z, Qi G, He X, Yu Y, Cao Y, Zhang C, Zou W, Yuan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2307388
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2307388
Glycyrrhizic acid attenuates sorafenib resistance by inducing ferroptosis via targeting mTOR signaling in hepatocellular carcinoma.
Hu Y, Luo Z, Cai S, Xie Q, Zheng S
Scandinavian journal of gastroenterology 2024 Jun;59(6):730-736
Scandinavian journal of gastroenterology 2024 Jun;59(6):730-736
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Zhao J, Shen J, Mao L, Yang T, Liu J, Hongbin S
Oncogene 2024 Jun;43(27):2104-2114
Oncogene 2024 Jun;43(27):2104-2114
Astragalus Polysaccharides and Metformin May Have Synergistic Effects on the Apoptosis and Ferroptosis of Lung Adenocarcinoma A549 Cells.
Lee IY, Wang TC, Kuo YJ, Shih WT, Yang PR, Hsu CM, Lin YS, Kuo RS, Wu CY
Current issues in molecular biology 2024 Jul 23;46(8):7782-7794
Current issues in molecular biology 2024 Jul 23;46(8):7782-7794
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Shi X, Yang J, Wang M, Xia L, Zhang L, Qiao S
Oncology letters 2024 Jan;27(1):2
Oncology letters 2024 Jan;27(1):2
Polyphyllin I induced ferroptosis to suppress the progression of hepatocellular carcinoma through activation of the mitochondrial dysfunction via Nrf2/HO-1/GPX4 axis.
Yang R, Gao W, Wang Z, Jian H, Peng L, Yu X, Xue P, Peng W, Li K, Zeng P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155135
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155135
Inhibition of Apoc1 reverses resistance of sorafenib by promoting ferroptosis in esophageal cancers.
Hu J, Hu H, Liu Q, Feng B, Lu Y, Chen K
Gene 2024 Jan 20;892:147874
Gene 2024 Jan 20;892:147874
Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury.
Liang Y, Wang Y, Sun C, Xiang Y, Deng Y
Brain research bulletin 2024 Feb;207:110878
Brain research bulletin 2024 Feb;207:110878
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Zhang W, Sun J, Liu F, Li S, Wang X, Su L, Liu G
Biological trace element research 2024 Feb;202(2):624-642
Biological trace element research 2024 Feb;202(2):624-642
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Dan Z, Shi X, Shu C, Zhu R, Wang Y, Zhu H
Cellular signalling 2024 Feb;114:111001
Cellular signalling 2024 Feb;114:111001
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
Zhou W, Lim A, Elmadbouh OHM, Edderkaoui M, Osipov A, Mathison AJ, Urrutia R, Liu T, Wang Q, Pandol SJ
Free radical biology & medicine 2024 Feb 20;212:493-504
Free radical biology & medicine 2024 Feb 20;212:493-504
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
Shen C, Jiang Y, Lin J, Guo Q, Fang D
Journal of molecular histology 2024 Dec;55(6):1163-1175
Journal of molecular histology 2024 Dec;55(6):1163-1175
NIR-Actuated Ferroptosis Nanomotor for Enhanced Tumor Penetration and Therapy.
Hu Z, Tan H, Ye Y, Xu W, Gao J, Liu L, Zhang L, Jiang J, Tian H, Peng F, Tu Y
Advanced materials (Deerfield Beach, Fla.) 2024 Dec;36(49):e2412227
Advanced materials (Deerfield Beach, Fla.) 2024 Dec;36(49):e2412227
Lif-deficiency promote systemic Iron metabolism disorders and increases the susceptibility of osteoblasts to ferroptosis.
Zhang Y, Cong Y, Du J, Guo D, Huang J, Pan J, Liang Y, Zhang J, Ye Z, Liu Y, Zhou Y
Bone 2024 Dec;189:117266
Bone 2024 Dec;189:117266
REV-ERBα inhibitor rescues MPTP/MPP(+)-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway.
Wang X, Wang M, Zhi H, Li J, Guo D
Heliyon 2024 Dec 15;10(23):e40388
Heliyon 2024 Dec 15;10(23):e40388
CCT3/ACTN4/TFRC axis protects hepatocellular carcinoma cells from ferroptosis by inhibiting iron endocytosis.
Zhu H, Liu Q, Meng Q, Zhang L, Ju S, Lang J, Zhu D, Chen Y, Aishan N, Ouyang X, Zhang S, Jin L, Xiao L, Wang L, Li L, Ji F
Journal of experimental & clinical cancer research : CR 2024 Aug 29;43(1):245
Journal of experimental & clinical cancer research : CR 2024 Aug 29;43(1):245
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Cai F, Li D, Zhou K, Zhang W, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407
Vitamin D Promotes Ferroptosis in Colorectal Cancer Stem Cells via SLC7A11 Downregulation.
Guo S, Zhao W, Zhang W, Li S, Teng G, Liu L
Oxidative medicine and cellular longevity 2023;2023:4772134
Oxidative medicine and cellular longevity 2023;2023:4772134
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Yin X, Yang Q, Li H, Kang Y, Li Z
Drug design, development and therapy 2023;17:283-295
Drug design, development and therapy 2023;17:283-295
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Zhu X, Wang S, Cheng Y, Gu H, Zhang X, Teng M, Zhang Y, Wang J, Hua W, Lu X
Frontiers in neuroscience 2023;17:1174455
Frontiers in neuroscience 2023;17:1174455
Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity by targeting mitochondrial ROS-mediated ferroptosis.
Ding SB, Chu XL, Jin YX, Jiang JJ, Zhao X, Yu M
Frontiers in pharmacology 2023;14:1148814
Frontiers in pharmacology 2023;14:1148814
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Lou L, Wang M, He J, Yang S, Meng F, Wang S, Jin X, Cai J, Cai C
Frontiers in pharmacology 2023;14:1067402
Frontiers in pharmacology 2023;14:1067402
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis.
Yang X, Yu Y, Li B, Chen Y, Feng M, Hu Y, Jiang W
PeerJ 2023;11:e15314
PeerJ 2023;11:e15314
Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis.
Yokote A, Imazu N, Umeno J, Kawasaki K, Fujioka S, Fuyuno Y, Matsuno Y, Moriyama T, Miyawaki K, Akashi K, Kitazono T, Torisu T
Journal of gastroenterology 2023 Sep;58(9):868-882
Journal of gastroenterology 2023 Sep;58(9):868-882
Tumor microenvironment-initiated lipid redox cycling for efficient triple-negative breast cancer therapy.
Zhou TJ, Wan X, Zhang MM, Liu DM, Huang LL, Xing L, Wang Y, Jiang HL
Biomaterials 2023 Sep;300:122205
Biomaterials 2023 Sep;300:122205
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Xiong L, Huang J, Wu C, Yuan Q, Wang S, Zhu L, Li Z, Sun Z, Fang Y, Li W, Hu G
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosis.
Cheng HP, Feng DD, Li XH, Gao LH, Qiu YJ, Liang XY, Zhou Y, Huang P, Shao M, Zhang YN, Chang YF, Fu JF, Huang YH, Liu W, Tang SY, Li C, Luo ZQ
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119535
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119535
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Wu Q, Liang Z, Jiang J, Feng X, Liu J, Zhang Z, Wang H, Wang N, Gou Y, Li Z, Cao Y
Cell death & disease 2023 Oct 11;14(10):668
Cell death & disease 2023 Oct 11;14(10):668
Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.
Yang Y, Wang Y, Deng Y, Lu J, Xiao L, Li J, Zhou Y, Nie F, Chen X, Peng J, Tan H, Qin Y, Peng Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547
Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications.
Sun S, Qi G, Chen H, He D, Ma D, Bie Y, Xu L, Feng B, Pang Q, Guo H, Zhang R
Cell death & disease 2023 Nov 18;14(11):754
Cell death & disease 2023 Nov 18;14(11):754
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
Hu P, Liu Y, Li S, Zhao Y, Gu H, Zong Q, Ahmed AA, Bao W, Liu HY, Cai D
Journal of agricultural and food chemistry 2023 May 31;71(21):8182-8191
Journal of agricultural and food chemistry 2023 May 31;71(21):8182-8191
G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration.
Li S, Liao Z, Yin H, Liu O, Hua W, Wu X, Zhang Y, Gao Y, Yang C
Cell proliferation 2023 Mar;56(3):e13368
Cell proliferation 2023 Mar;56(3):e13368
AMPK activation alleviated dextran sulfate sodium-induced colitis by inhibiting ferroptosis.
Sun SP, Lu YF, Li H, Weng CY, Chen JJ, Lou YJ, Lyu D, Lyu B
Journal of digestive diseases 2023 Mar;24(3):213-223
Journal of digestive diseases 2023 Mar;24(3):213-223
Identification of a ferroptosis-related gene signature for prognosis prediction in colorectal cancer patients and relationship with vitamin D.
Guo S, Zhao W, Zhang T, Li S, Guo J, Liu L
The Journal of steroid biochemistry and molecular biology 2023 Mar;227:106234
The Journal of steroid biochemistry and molecular biology 2023 Mar;227:106234
Evodiamine Exhibits Anti-Bladder Cancer Activity by Suppression of Glutathione Peroxidase 4 and Induction of Ferroptosis.
Hu CY, Wu HT, Shan YS, Wang CT, Shieh GS, Wu CL, Ou HY
International journal of molecular sciences 2023 Mar 23;24(7)
International journal of molecular sciences 2023 Mar 23;24(7)
Homocysteine induces ferroptosis in endothelial cells through the systemXc(-)/GPX4 signaling pathway.
Shi J, Chen D, Wang Z, Li S, Zhang S
BMC cardiovascular disorders 2023 Jun 24;23(1):316
BMC cardiovascular disorders 2023 Jun 24;23(1):316
Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing.
Liu X, Cui Z, Chen X, Li Y, Qiu J, Huang Y, Wang X, Chen S, Luo Q, Chen P, Zhuang J, Yu K
Investigative ophthalmology & visual science 2023 Jun 1;64(7):27
Investigative ophthalmology & visual science 2023 Jun 1;64(7):27
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874
Heliyon 2023 Jul;9(7):e17874
Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
Zhang M, Yu Z, Zhao L, Luo H
Biochemical and biophysical research communications 2023 Jul 30;667:170-179
Biochemical and biophysical research communications 2023 Jul 30;667:170-179
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Wen RJ, Dong X, Zhuang HW, Pang FX, Ding SC, Li N, Mai YX, Zhou ST, Wang JY, Zhang JF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154881
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Ma B, Zhong Y, Chen R, Zhan X, Huang G, Xiong Y, Tan B
Biochemical and biophysical research communications 2023 Jul 12;665:178-186
Biochemical and biophysical research communications 2023 Jul 12;665:178-186
TRIM59 promotes steatosis and ferroptosis in non-alcoholic fatty liver disease via enhancing GPX4 ubiquitination.
Zhang J, Xie H, Yao J, Jin W, Pan H, Pan Z, Xie D, Xie D
Human cell 2023 Jan;36(1):209-222
Human cell 2023 Jan;36(1):209-222
Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis.
Yu S, Zeng Y, Ruan C, Bai L, Liang Z
Human & experimental toxicology 2023 Jan-Dec;42:9603271231184630
Human & experimental toxicology 2023 Jan-Dec;42:9603271231184630
Increased expression of GPX4 promotes the tumorigenesis of thyroid cancer by inhibiting ferroptosis and predicts poor clinical outcomes.
Chen H, Peng F, Xu J, Wang G, Zhao Y
Aging 2023 Jan 9;15(1):230-245
Aging 2023 Jan 9;15(1):230-245
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Guo C, Lyu Y, Xia S, Ren X, Li Z, Tian F, Zheng J
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
pH-sensitive molybdenum (Mo)-based polyoxometalate nanoclusters have therapeutic efficacy in inflammatory bowel disease by counteracting ferroptosis.
Yang F, Chen Y, Xiao Y, Jiang H, Jiang Z, Yang M, Li M, Su Y, Yan Z, Lin Y, Li D
Pharmacological research 2023 Feb;188:106645
Pharmacological research 2023 Feb;188:106645
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
Amos A, Jiang N, Zong D, Gu J, Zhou J, Yin L, He X, Xu Y, Wu L
BMC cancer 2023 Feb 3;23(1):117
BMC cancer 2023 Feb 3;23(1):117
Thermoresponsive Ozone-Enriched Spray Gel for Postsurgical Treatment of Hepatocellular Carcinoma.
Zhang Y, Zhang C, Wu B, Li C, Lin J, Huang P
ACS nano 2023 Feb 28;17(4):3518-3527
ACS nano 2023 Feb 28;17(4):3518-3527
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation.
Li H, Weng Q, Gong S, Zhang W, Wang J, Huang Y, Li Y, Guo J, Lan T
Food & function 2023 Feb 21;14(4):1884-1896
Food & function 2023 Feb 21;14(4):1884-1896
Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway.
Yang CS, Guo XS, Yue YY, Wang Y, Jin XL
International journal of molecular sciences 2023 Feb 14;24(4)
International journal of molecular sciences 2023 Feb 14;24(4)
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Ding J, Lu B, Liu L, Zhong Z, Wang N, Li B, Sheng W, He Q
Pharmaceutical biology 2023 Dec;61(1):213-227
Pharmaceutical biology 2023 Dec;61(1):213-227
Role of GPX4 inhibition-mediated ferroptosis in the chemoresistance of ovarian cancer to Taxol in vitro.
Feng Q, Hao S, Fang P, Zhang P, Sheng X
Molecular biology reports 2023 Dec;50(12):10189-10198
Molecular biology reports 2023 Dec;50(12):10189-10198
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
Bu H, Wang B, Wu Y, Li P, Cui Y, Jiang X, Yu X, Liu B, Tang M
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
PS-MPs or their co-exposure with cadmium impair male reproductive function through the miR-199a-5p/HIF-1α-mediated ferroptosis pathway.
Zhang Q, Xia W, Zhou X, Yang C, Lu Z, Wu S, Lu X, Yang J, Jin C
Environmental pollution (Barking, Essex : 1987) 2023 Dec 15;339:122723
Environmental pollution (Barking, Essex : 1987) 2023 Dec 15;339:122723
HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1.
Yang Z, Su W, Wei X, Qu S, Zhao D, Zhou J, Wang Y, Guan Q, Qin C, Xiang J, Zen K, Yao B
Cell reports 2023 Aug 29;42(8):112945
Cell reports 2023 Aug 29;42(8):112945
Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway.
Chen X, Song QL, Li ZH, Ji R, Wang JY, Cao ML, Mu XF, Zhang Y, Guo DY, Yang J
Archives of biochemistry and biophysics 2023 Apr;738:109561
Archives of biochemistry and biophysics 2023 Apr;738:109561
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Gong Z, Wang Y, Li L, Li X, Qiu B, Hu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113644
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113644
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Han N, Yang ZY, Xie ZX, Xu HZ, Yu TT, Li QR, Li LG, Peng XC, Yang XX, Hu J, Xu X, Chen X, Wang MF, Li TF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154682
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154682
Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
Chen L, Huang J, Yao ZM, Sun XR, Tong XH, Hu M, Zhang Y, Dong SY
Molecules (Basel, Switzerland) 2023 Apr 20;28(8)
Molecules (Basel, Switzerland) 2023 Apr 20;28(8)
The Effects of Alda-1 Treatment on Renal and Intestinal Injuries After Cardiopulmonary Resuscitation in Pigs.
Yu Q, Gao J, Shao X, Lu W, Chen L, Jin L
Frontiers in medicine 2022;9:892472
Frontiers in medicine 2022;9:892472
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Shi H, Yan Y, Yang H, Pu P, Tang H
BioMed research international 2022;2022:5623555
BioMed research international 2022;2022:5623555
Activated Stellate Cell Paracrine HGF Exacerbated Pancreatic Cancer Cell Ferroptosis Resistance.
Wu Q, Song L, Guo Y, Liu S, Wang W, Liu H, Gong A, Liao X, Zhu H, Wang D
Oxidative medicine and cellular longevity 2022;2022:2985249
Oxidative medicine and cellular longevity 2022;2022:2985249
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Song J, Sheng J, Lei J, Gan W, Yang Y
Oxidative medicine and cellular longevity 2022;2022:2223957
Oxidative medicine and cellular longevity 2022;2022:2223957
Pyrocatechol Alleviates Cisplatin-Induced Acute Kidney Injury by Inhibiting ROS Production.
Xie X, Wu F, Tian J, Liu Z, He H, Bao D, Li G, Li H, Chen J, Lai Y, Chen Z, Fan J, Chen G, Lai C
Oxidative medicine and cellular longevity 2022;2022:2158644
Oxidative medicine and cellular longevity 2022;2022:2158644
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Xiao S, Zhou Y, Wang Q, Yang D
Drug design, development and therapy 2022;16:4411-4428
Drug design, development and therapy 2022;16:4411-4428
Probiotic Saccharomyces boulardii attenuates cardiopulmonary bypass-induced acute lung injury by inhibiting ferroptosis.
Li J, Gao PF, Xu YX, Gu H, Wang QX
American journal of translational research 2022;14(7):5003-5013
American journal of translational research 2022;14(7):5003-5013
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage.
Li LG, Peng XC, Yu TT, Xu HZ, Han N, Yang XX, Li QR, Hu J, Liu B, Yang ZY, Xu X, Chen X, Wang MF, Li TF
Frontiers in pharmacology 2022;13:949835
Frontiers in pharmacology 2022;13:949835
Naringin Relieves Diabetic Cardiac Autonomic Neuropathy Mediated by P2Y(14) Receptor in Superior Cervical Ganglion.
Tang G, Pi L, Guo H, Hu Z, Zhou C, Hu Q, Peng H, Xiao Z, Zhang Z, Wang M, Peng T, Huang J, Liang S, Li G
Frontiers in pharmacology 2022;13:873090
Frontiers in pharmacology 2022;13:873090
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
Peng X, Yang R, Peng W, Zhao Z, Tu G, He B, Cai Q, Shi S, Yin W, Yu F, Tao Y, Wang X
PeerJ 2022;10:e14180
PeerJ 2022;10:e14180
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Dang Y, He Q, Yang S, Sun H, Liu Y, Li W, Tang Y, Zheng Y, Wu T
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Guan S, Zhang R, Zhao Y, Meng Z, Lu J
Environmental toxicology 2022 Oct;37(10):2515-2528
Environmental toxicology 2022 Oct;37(10):2515-2528
Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes.
Wang X, Liu Z, Peng P, Gong Z, Huang J, Peng H
Chemico-biological interactions 2022 Oct 1;366:110148
Chemico-biological interactions 2022 Oct 1;366:110148
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
Jiang Z, Wang H, Qi G, Jiang C, Chen K, Yan Z
IUBMB life 2022 Nov;74(11):1052-1069
IUBMB life 2022 Nov;74(11):1052-1069
The Clock gene regulates kainic acid-induced seizures through inhibiting ferroptosis in mice.
Wang F, Guo L, Wu Z, Zhang T, Dong D, Wu B
The Journal of pharmacy and pharmacology 2022 Nov 4;74(11):1640-1650
The Journal of pharmacy and pharmacology 2022 Nov 4;74(11):1640-1650
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Han P, Wang X, Zhou T, Cheng J, Wang C, Sun F, Zhao X
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2/HO-1 pathway.
Jin T, Chen C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 May;163:112892
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 May;163:112892
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
Yang XX, Xu X, Wang MF, Xu HZ, Peng XC, Han N, Yu TT, Li LG, Li QR, Chen X, Wen Y, Li TF
Journal of nanobiotechnology 2022 May 14;20(1):230
Journal of nanobiotechnology 2022 May 14;20(1):230
BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection.
Chen Y, Yi X, Huo B, He Y, Guo X, Zhang Z, Zhong X, Feng X, Fang ZM, Zhu XH, Wei X, Jiang DS
Pharmacological research 2022 Mar;177:106122
Pharmacological research 2022 Mar;177:106122
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancerthrough inhibiting GPX4 and enhancing ROS.
Han N, Li LG, Peng XC, Ma QL, Yang ZY, Wang XY, Li J, Li QR, Yu TT, Xu HZ, Xu X, Chen X, Wang MF, Li TF
European journal of pharmacology 2022 Mar 15;919:174797
European journal of pharmacology 2022 Mar 15;919:174797
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Liu H, He S, Wang J, Li C, Liao Y, Zou Q, Chen R
Neurochemical research 2022 Jun;47(6):1574-1587
Neurochemical research 2022 Jun;47(6):1574-1587
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
Zeng Z, Huang H, Zhang J, Liu Y, Zhong W, Chen W, Lu Y, Qiao Y, Zhao H, Meng X, Zou F, Cai S, Dong H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22359
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22359
Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy.
Liu P, Lin C, Liu Z, Zhu C, Lin Z, Xu D, Chen J, Huang Q, Li CY, Hou L, Pan JA, Liu X
Cellular and molecular life sciences : CMLS 2022 Jun 8;79(7):352
Cellular and molecular life sciences : CMLS 2022 Jun 8;79(7):352
A Multifunctional Vanadium-Iron-Oxide Nanoparticle Eradicates Hepatocellular Carcinoma via Targeting Tumor and Endothelial Cells.
Yang X, Xiao J, Jiang L, Ran L, Fan Y, Zhang M, Xu Y, Yao C, An B, Yang Y, Yang C, Tian G, Zhang G, Zhang Y
ACS applied materials & interfaces 2022 Jun 29;14(25):28514-28526
ACS applied materials & interfaces 2022 Jun 29;14(25):28514-28526
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM(2.5).
Shi F, Zhang Z, Cui H, Wang J, Wang Y, Tang Y, Yang W, Zou P, Ling X, Han F, Liu J, Chen Q, Liu C, Cao J, Ao L
Ecotoxicology and environmental safety 2022 Jun 15;238:113569
Ecotoxicology and environmental safety 2022 Jun 15;238:113569
Ferroptosis, as the most enriched programmed cell death process in glioma, induces immunosuppression and immunotherapy resistance.
Liu T, Zhu C, Chen X, Guan G, Zou C, Shen S, Wu J, Wang Y, Lin Z, Chen L, Cheng P, Cheng W, Wu A
Neuro-oncology 2022 Jul 1;24(7):1113-1125
Neuro-oncology 2022 Jul 1;24(7):1113-1125
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
Sun S, Gao T, Pang B, Su X, Guo C, Zhang R, Pang Q
Cell death & disease 2022 Jan 21;13(1):73
Cell death & disease 2022 Jan 21;13(1):73
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Shao C, Liu Y, Chen Z, Qin Y, Wang X, Wang X, Yan C, Zhu HL, Zhao J, Qian Y
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury.
He R, Liu B, Xiong R, Geng B, Meng H, Lin W, Hao B, Zhang L, Wang W, Jiang W, Li N, Geng Q
Cell death discovery 2022 Feb 2;8(1):43
Cell death discovery 2022 Feb 2;8(1):43
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
Low Sulfur Amino Acid, High Polyunsaturated Fatty Acid Diet Inhibits Breast Cancer Growth.
Turchi R, Tortolici F, Benvenuto M, Punziano C, De Luca A, Rufini S, Faraonio R, Bei R, Lettieri-Barbato D, Aquilano K
International journal of molecular sciences 2022 Dec 23;24(1)
International journal of molecular sciences 2022 Dec 23;24(1)
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
Wu L, Tian X, Zuo H, Zheng W, Li X, Yuan M, Tian X, Song H
Journal of nanobiotechnology 2022 Apr 22;20(1):196
Journal of nanobiotechnology 2022 Apr 22;20(1):196
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
Ulinastatin protects against acetaminophen-induced liver injury by alleviating ferroptosis via the SIRT1/NRF2/HO-1 pathway.
Wang C, Liu T, Tong Y, Cui R, Qu K, Liu C, Zhang J
American journal of translational research 2021;13(6):6031-6042
American journal of translational research 2021;13(6):6031-6042
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400
Frontiers in genetics 2021;12:774400
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223
Frontiers in pharmacology 2021;12:681223
HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia.
Li X, Wang M, Li S, Chen Y, Wang M, Wu Z, Sun X, Yao L, Dong H, Song Y, Xu Y
Theranostics 2021;11(15):7337-7359
Theranostics 2021;11(15):7337-7359
Proteome Analysis of Camellia nitidissima Chi Revealed Its Role in Colon Cancer Through the Apoptosis and Ferroptosis Pathway.
Chen Y, Zhang F, Du Z, Xie J, Xia L, Hou X, Hao E, Deng J
Frontiers in oncology 2021;11:727130
Frontiers in oncology 2021;11:727130
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
Wei J, Nai GY, Dai Y, Huang XJ, Xiong MY, Yao XY, Huang ZN, Li SN, Zhou WJ, Huang Y, Cheng P, Deng DH
Annals of translational medicine 2021 Sep;9(17):1381
Annals of translational medicine 2021 Sep;9(17):1381
Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice.
Ikeda Y, Hamano H, Horinouchi Y, Miyamoto L, Hirayama T, Nagasawa H, Tamaki T, Tsuchiya K
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 Sep;67:126798
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 Sep;67:126798
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
He Y, Fang D, Liang T, Pang H, Nong Y, Tang L, Yang Z, Lu C, Han X, Zhao S, Mo S, Meng Y, Han C, Peng T
Annals of translational medicine 2021 Oct;9(20):1535
Annals of translational medicine 2021 Oct;9(20):1535
Novel function of fluvastatin in attenuating oxidized low-density lipoprotein-induced endothelial cell ferroptosis in a glutathione peroxidase4- and cystine-glutamate antiporter-dependent manner.
Li Q, Liu C, Deng L, Xie E, Yadav N, Tie Y, Cheng Z, Deng J
Experimental and therapeutic medicine 2021 Nov;22(5):1275
Experimental and therapeutic medicine 2021 Nov;22(5):1275
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Bao WD, Pang P, Zhou XT, Hu F, Xiong W, Chen K, Wang J, Wang F, Xie D, Hu YZ, Han ZT, Zhang HH, Wang WX, Nelson PT, Chen JG, Lu Y, Man HY, Liu D, Zhu LQ
Cell death and differentiation 2021 May;28(5):1548-1562
Cell death and differentiation 2021 May;28(5):1548-1562
Combination of ponatinib with deferoxamine synergistically mitigates ischemic heart injury via simultaneous prevention of necroptosis and ferroptosis.
Tu H, Zhou YJ, Tang LJ, Xiong XM, Zhang XJ, Ali Sheikh MS, Zhang JJ, Luo XJ, Yuan C, Peng J
European journal of pharmacology 2021 May 5;898:173999
European journal of pharmacology 2021 May 5;898:173999
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
Zhang M, Zhang T, Song C, Qu J, Gu Y, Liu S, Li H, Xiao W, Kong L, Sun Y, Lv W
Journal of ethnopharmacology 2021 Jun 28;274:114064
Journal of ethnopharmacology 2021 Jun 28;274:114064
Dihydroisotanshinone I induced ferroptosis and apoptosis of lung cancer cells.
Wu CY, Yang YH, Lin YS, Chang GH, Tsai MS, Hsu CM, Yeh RA, Shu LH, Cheng YC, Liu HT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111585
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111585
SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18.
Su G, Yang W, Wang S, Geng C, Guan X
Biochemical and biophysical research communications 2021 Jul 5;561:33-39
Biochemical and biophysical research communications 2021 Jul 5;561:33-39
Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs.
Wang S, Bai M, Xu K, Shao Y, Yang Z, Xiong X, Huang R, Li Y, Liu H
Animals : an open access journal from MDPI 2021 Jul 27;11(8)
Animals : an open access journal from MDPI 2021 Jul 27;11(8)
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis.
He Z, Liao W, Song Q, Li B, Liu J, Xiong Y, Song C, Yang S
International journal of molecular medicine 2021 Jan;47(1):289-301
International journal of molecular medicine 2021 Jan;47(1):289-301
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
Guo L, Zhang T, Wang F, Chen X, Xu H, Zhou C, Chen M, Yu F, Wang S, Yang D, Wu B
British journal of pharmacology 2021 Jan;178(2):328-345
British journal of pharmacology 2021 Jan;178(2):328-345
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Bai Y, Wang W, Wang L, Ma L, Zhai D, Wang F, Shi R, Liu C, Xu Q, Chen G, Lu Z
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis.
Cheng H, Feng D, Li X, Gao L, Tang S, Liu W, Wu X, Yue S, Li C, Luo Z
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166204
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166204
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
Deng SH, Wu DM, Li L, Liu T, Zhang T, Li J, Yu Y, He M, Zhao YY, Han R, Xu Y
Biochemical and biophysical research communications 2021 Apr 16;549:54-60
Biochemical and biophysical research communications 2021 Apr 16;549:54-60
IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer.
Zhang L, Liu W, Liu F, Wang Q, Song M, Yu Q, Tang K, Teng T, Wu D, Wang X, Han W, Li Y
Oxidative medicine and cellular longevity 2020;2020:1675613
Oxidative medicine and cellular longevity 2020;2020:1675613
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Deng HF, Yue LX, Wang NN, Zhou YQ, Zhou W, Liu X, Ni YH, Huang CS, Qiu LZ, Liu H, Tan HL, Tang XL, Wang YG, Ma ZC, Gao Y
Frontiers in pharmacology 2020;11:624529
Frontiers in pharmacology 2020;11:624529
Fasting Drives Nrf2-Related Antioxidant Response in Skeletal Muscle.
Lettieri-Barbato D, Minopoli G, Caggiano R, Izzo R, Santillo M, Aquilano K, Faraonio R
International journal of molecular sciences 2020 Oct 21;21(20)
International journal of molecular sciences 2020 Oct 21;21(20)
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L
Cell death & disease 2020 Jul 24;11(7):574
Cell death & disease 2020 Jul 24;11(7):574
Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1.
Li X, Duan L, Yuan S, Zhuang X, Qiao T, He J
Journal of inflammation (London, England) 2019;16:11
Journal of inflammation (London, England) 2019;16:11
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
Danshen Improves Survival of Patients With Breast Cancer and Dihydroisotanshinone I Induces Ferroptosis and Apoptosis of Breast Cancer Cells.
Lin YS, Shen YC, Wu CY, Tsai YY, Yang YH, Lin YY, Kuan FC, Lu CN, Chang GH, Tsai MS, Hsu CM, Yeh RA, Yang PR, Lee IY, Shu LH, Cheng YC, Liu HT, Wu YH, Wu YH, Chang DC
Frontiers in pharmacology 2019;10:1226
Frontiers in pharmacology 2019;10:1226
Role of ferroptosis in the process of acute radiation-induced lung injury in mice.
Li X, Zhuang X, Qiao T
Biochemical and biophysical research communications 2019 Nov 5;519(2):240-245
Biochemical and biophysical research communications 2019 Nov 5;519(2):240-245
Adipose-Specific Lipin-1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice.
Zhou Z, Ye TJ, Bonavita G, Daniels M, Kainrad N, Jogasuria A, You M
Hepatology communications 2019 May;3(5):656-669
Hepatology communications 2019 May;3(5):656-669
Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.
Pandey S, Kuo WW, Shen CY, Yeh YL, Ho TJ, Chen RJ, Chang RL, Pai PY, Viswanadha VP, Huang CY, Huang CY
American journal of physiology. Cell physiology 2019 Aug 1;317(2):C235-C243
American journal of physiology. Cell physiology 2019 Aug 1;317(2):C235-C243
Effects of autophagy on the spermatogonia of chronic hypoxic mice.
Zhu S, Li W, Yang X, Yu W, Rao T, Ruan Y, Ning J, Yuan R, Li H, Jiang K, Li C, Cheng F
American journal of translational research 2018;10(12):4119-4129
American journal of translational research 2018;10(12):4119-4129
Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development.
Saudrais E, Strazielle N, Ghersi-Egea JF
American journal of physiology. Cell physiology 2018 Oct 1;315(4):C445-C456
American journal of physiology. Cell physiology 2018 Oct 1;315(4):C445-C456
Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice.
Jiang Y, Liu C, Lei B, Xu X, Lu B
Andrologia 2018 Mar;50(2)
Andrologia 2018 Mar;50(2)
Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
Min Z, Guo Y, Sun M, Hussain S, Zhao Y, Guo D, Huang H, Heng L, Zhang F, Ning Q, Han Y, Xu P, Zhong N, Sun J, Lu S
Journal of cellular and molecular medicine 2018 Dec;22(12):5888-5898
Journal of cellular and molecular medicine 2018 Dec;22(12):5888-5898
Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.
Thomas NO, Shay KP, Kelley AR, Butler JA, Hagen TM
Redox biology 2016 Dec;10:45-52
Redox biology 2016 Dec;10:45-52
Alteration of sperm protein profile induced by cigarette smoking.
Chen X, Xu W, Miao M, Zhu Z, Dai J, Chen Z, Fang P, Wu J, Nie D, Wang L, Wang Z, Qiao Z, Shi H
Acta biochimica et biophysica Sinica 2015 Jul;47(7):504-15
Acta biochimica et biophysica Sinica 2015 Jul;47(7):504-15
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14432-1-AP(GPX4 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 14432-1-AP(GPX4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GPX4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GPX4. This antibody recognizes human,mouse,rat antigen. The GPX4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
