ABIN374711

antibody from antibodies-online

Targeting: GPX4 MCSP, PHGPx

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN374711

Provider

antibodies-online

Product name

anti-Glutathione Peroxidase 4 (GPX4) (Isoform a,C-Term) antibody

Antibody type

Polyclonal

Antigen

Peptide with sequence C-EEPLVIEKDLPHY, from the C Terminus of the protein sequence

Reactivity

Human, Mouse, Rat, Bovine, Porcine

Host

Goat

Vial size

0.1 mg

Concentration

0.5 mg/ml

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.

Schoenmakers E, Agostini M, Mitchell C, Schoenmakers N, Papp L, Rajanayagam O, Padidela R, Ceron-Gutierrez L, Doffinger R, Prevosto C, Luan J, Montano S, Lu J, Castanet M, Clemons N, Groeneveld M, Castets P, Karbaschi M, Aitken S, Dixon A, Williams J, Campi I, Blount M, Burton H, Muntoni F, O'Donovan D, Dean A, Warren A, Brierley C, Baguley D, Guicheney P, Fitzgerald R, Coles A, Gaston H, Todd P, Holmgren A, Khanna KK, Cooke M, Semple R, Halsall D, Wareham N, Schwabe J, Grasso L, Beck-Peccoz P, Ogunko A, Dattani M, Gurnell M, Chatterjee K
The Journal of clinical investigation 2010 Dec;120(12):4220-35

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SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress.

Papp LV, Lu J, Bolderson E, Boucher D, Singh R, Holmgren A, Khanna KK
Antioxidants & redox signaling 2010 Apr 1;12(7):797-808