Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- ABIN185669 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN185669, RRID:AB_10781103
- Product name
- anti-Glutathione Peroxidase (GPX4) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Reactivity
- Human
- Host
- Goat
- Epitope
- C-Term
- Vial size
- 100 μg
- Storage
- Aliquot and store at -20°C.
- Handling
- Minimize freezing and thawing.
Submitted references Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.
SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress.
Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation.
Schoenmakers E, Agostini M, Mitchell C, Schoenmakers N, Papp L, Rajanayagam O, Padidela R, Ceron-Gutierrez L, Doffinger R, Prevosto C, Luan J, Montano S, Lu J, Castanet M, Clemons N, Groeneveld M, Castets P, Karbaschi M, Aitken S, Dixon A, Williams J, Campi I, Blount M, Burton H, Muntoni F, O'Donovan D, Dean A, Warren A, Brierley C, Baguley D, Guicheney P, Fitzgerald R, Coles A, Gaston H, Todd P, Holmgren A, Khanna KK, Cooke M, Semple R, Halsall D, Wareham N, Schwabe J, Grasso L, Beck-Peccoz P, Ogunko A, Dattani M, Gurnell M, Chatterjee K
The Journal of clinical investigation 2010 Dec;120(12):4220-35
The Journal of clinical investigation 2010 Dec;120(12):4220-35
SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress.
Papp LV, Lu J, Bolderson E, Boucher D, Singh R, Holmgren A, Khanna KK
Antioxidants & redox signaling 2010 Apr 1;12(7):797-808
Antioxidants & redox signaling 2010 Apr 1;12(7):797-808
Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation.
Su D, Novoselov SV, Sun QA, Moustafa ME, Zhou Y, Oko R, Hatfield DL, Gladyshev VN
The Journal of biological chemistry 2005 Jul 15;280(28):26491-8
The Journal of biological chemistry 2005 Jul 15;280(28):26491-8
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