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- Antigen structure
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- Product number
- 26975-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- NeuN antibody
- Antibody type
- Polyclonal
- Description
- NeuN antibody (Cat. #26975-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Novel LncRNA Gm44763 Regulates Morphine-Induced Reward Memory via MiR-298-5p-Mediated eIF4E Translation Control.
Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice.
Therapeutic relevance of an EU-GMP certified Cannabis sativa L. strain in a dual in vivo model of cognitive impairment and chronic neuropathic pain.
Adenosine A(2A) receptors regulate D(2)-type medium spiny neurons in the nucleus accumbens to mediate pain and depression comorbidity.
Gastrodia elata fermentation alleviates methamphetamine-induced neuroinflammation and anxiety- and depression-like behaviors by regulating the PI3K-AKT signaling pathway.
hUCMSC mitochondrial EVs confer neuroprotection after ischemia by Tom1l2-mediated mitochondrial fusion and Crls1-cardiolipin axis reprogramming.
Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
Polygonatum Sibiricum polysaccharide ameliorates Alzheimer's disease by alleviating cuproptosis and activating the PI3K/AKT signaling pathway.
Decoding COPD-related cognitive impairment: The protective potential of YTHDF1.
Elevation of H(2)S Underlies Social Deficits in Environmental Factor Double-Hit Autism Model.
Microglial NLRP3-dependent pyroptosis promotes cognitive dysfunction of diabetic encephalopathy by inhibiting adult hippocampal neurogenesis through the release of IL-1β.
A Novel Polysaccharide (ZJP-2) from Wild Jujube Alleviates Oxidative Damage in Neural Stem Cells: Structural Features and Bioactivity.
Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
M2 macrophage-derived exosomes delivering haptoglobin and interleukin-10 plasmids for synergistic therapy of intracerebral hemorrhage.
Indole metabolites produced by Lactobacillus acidophilus impedes bisphenol F- aryl hydrocarbon receptor interaction and ameliorates bisphenol F induced depression-like changes.
Spinal cord injury-derived exosomes exacerbate damage: miR-155-5p mediates inflammatory responses.
ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model.
Cycloastragenol protected hippocampal CA1 neurons by regulating redox homeostasis and alleviated cognitive impairment following cerebral ischemia-reperfusion.
Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury.
Electroacupuncture at Zusanli (ST36) alleviates paclitaxel-induced neuropathic pain in rats via regulating TLR4 signaling pathway in the spinal cord.
Sennoside A ameliorates cognitive impairment by inhibiting USP14/ERK1/2 pathway in a mouse model of type 2 diabetes mellitus.
Sodium tanshinone IIA sulfonate alleviates neuroinflammation-induced damage to hippocampal neurons by activating SIRT1 in mice with sepsis-associated encephalopathy.
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
SATB1 Exhibits a Protective Role in HAmylin-Oligomer-Induced Neuronal Damage and Cognition Decline.
hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.
KANK4 Regulates CXCL16 Glycosylation Through TMEM260 to Modulate Microglial Activation in Sepsis-associated Encephalopathy.
Glioblastoma-secreted C1QL1 orchestrates tumor microtube expansion and neural synaptic pruning to drive malignant synapse formation and recurrence.
Exploring the Role of TSPO-PET Imaging Among MRI-Negative Patients with Temporal Lobe Epilepsy: From the Perspective of Heterogeneity.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Protective Effects of Crocin Against Fluoride-Induced Neurotoxicity: Involvement of Wnt10b/β-Catenin Signaling.
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
ELAVL1 interacts with APP and promotes Aβ-induced apoptosis in Alzheimer's disease by activating Bcl-2/Bax signaling.
Bio-inspired spatiotemporal cascade reaction liposome for ferroptosis treatment following subarachnoid hemorrhage.
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.
SERPINE1 drives neuropathic pain in a resiniferatoxin-induced model via AKT-mediated neuronal apoptosis.
Targeting the ARRDC3-DRP1 Axis via hUMSC-Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury.
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Pretreatment with a ketogenic diet inhibits mitochondrial damage in rat models of spinal cord injury via the PGC-1α/Sirt1/Nrf1 pathway.
Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice.
Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction.
Yttrium Oxide Nanoparticles Affect Both Cognitive and Memory Function by Disrupting Copper Output in Neuronal Cells in a Rat Model.
Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury.
Bioinformatics analysis of electroacupuncture treatment for ischemic stroke: exploring transcriptional regulatory mechanisms mediated by super-enhancers.
Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3β/NRF2 Pathway.
The active metabolite of Epimedii Folium promotes hippocampal neurogenesis in APP/PS1 mice by alleviating mitochondrial dysfunction.
Exploring the potential anti-senescence effects of soybean-derived peptide Soymetide in mice hippocampal neurons via the Wnt/β-catenin pathway.
Salvianolic acid B exerts cerebroprotective effects after traumatic brain injury via Nrf2-dependent antioxidant and anti-inflammatory cascades.
Senescent Microglia Mediate Neuroinflammation-Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1.
Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis.
N-acetyltransferase 10 in the nucleus accumbens participates in methamphetamine-induced conditioned place preference and hyperlocomotion in mice.
Protecting the brain from stroke: Huoxue Rongluo formula (HXRLF) targets ferroptosis for neuroprotection.
Excessive mitochondrial stress response triggers neuronal injury through the persistent eIF2α phosphorylation in mice exposed to manganese.
Activation of CB1R alleviates autism spectrum disorder-like behavior and synaptic impairments.
Boosting 2-arachidonoylglycerol, but not N-acylethanolamine, ameliorates autism symptoms in VPA-exposed rats by modulating abnormal neuroinflammation.
Peripheral administration of the NAT10 inhibitor Remodelin prevents against Lipopolysaccharide induced depression in male mice.
EphB receptors modulate neuropathic pain via Ca(2+)/calpain/autophagy in spinal cord of mice.
ETV5 improves ischemic stroke by targeting HACE1/Nrf2 axis to inhibit microglia M1 polarization and neuron pyroptosis.
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage.
Glutamatergic Neurons in the Cerebellar Lateral Nucleus Contribute to Motor Deficits Induced by Chronic Sleep Disturbance.
Neonatal sevoflurane anesthesia induces persistent cognitive deficits in mice through CypD-dependent mitochondrial impairment in parvalbumin interneurons.
Panax notoginseng Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis.
Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's disease.
Pramipexole improves cognitive deficits and synaptic plasticity impairments in 3xTg-AD mice through enhancing autophagy.
Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke.
CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.
Cassini: streamlined and scalable method for in situ profiling of RNA and protein.
S100A11 mediates the protective effects of edaravone dexborneol on docetaxel-induced cognitive impairment in rats by inhibiting the MAPK signaling pathway.
Human Cortical Organoids with a Novel SCN2A Variant Exhibit Hyperexcitability and Differential Responses to Anti-Seizure Compounds.
Aerobic Exercise Training Exerts Neuroprotective Effects in Alzheimer's Disease Mice by Regulating Endoplasmic Reticulum Stress-Autophagy Pathway-Mediated Pyroptosis.
Astrocyte-microglia crosstalk in the hippocampus mediates cognitive impairments induced by chronic intermittent hypoxia.
Transcranial direct current stimulation attenuates cerebral ischemia-reperfusion injury by inhibiting neuronal pyroptosis via Netrin-1.
METTL3 modulates bone Cancer pain via m(6)A-dependent JAK2/STAT3 activation in spinal astrocytes.
Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance.
Circulating Cathepsin D Exacerbates Injury-Induced Brain Damage by Promoting Neutrophil Infiltration Into the Brain.
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.
Olfactory ensheathing cell transplantation alleviates cancer pain by inhibiting P2X7 receptor expression-mediated activation of microglia.
Genetic Ablation of Sarm1 Mitigates Disease Acceleration after Traumatic Brain Injury in the SOD1(G93A) Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
Hydrogen sulfide improves depression-like behaviors in CUMS-induced mice by regulating autophagy.
Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN.
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
PARP14 inhibits microglial activation via NNT to alleviate depressive-like behaviors in mice.
Rilmenidine attenuates intracerebral hemorrhage by regulating autophagy flux and apoptosis via the HO-1/Fe(2+)/ERK pathway.
Paclitaxel alleviates spinal cord injury via activation of the Wnt/β-catenin signaling pathway.
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
TREM2 deficiency exacerbates cognitive impairment by aggravating α-Synuclein-induced lysosomal dysfunction in Parkinson's disease.
Tanshinone IIA Promotes Functional Recovery After Spinal Cord Injury by Inhibiting Neuron and Oligodendrocyte Ferroptosis Through the GPX4/ACSL4 Axis.
Region-specific Brain Targets Drive Circuit Formation and Maturation of Human Retinal Ganglion Cells.
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus.
Glial scarring limits recovery following decompressive surgery in rats with syringomyelia.
Hydrogen Sulfide Sustained Release Donor Alleviates Spinal Cord Ischemia-Reperfusion-Induced Neuron Death by Inhibiting Ferritinophagy-Mediated Ferroptosis.
Elucidation of Dexmedetomidine-Induced Analgesic Tolerance Mechanisms in Neuropathic Pain With Modulation of SGK1, NR2A, and NR2B Expression via the Spinal SGK1/NF-κB Signalling Pathway.
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Egln3 expression in microglia enhances the neuroinflammatory responses in Alzheimer's disease.
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction.
PLGA-Encapsulated Elvitegravir and Curcumin Modulates ART Penetration, Oxidative Stress, and Inflammation.
FKBP51 is Involved in Epileptic Seizure by Regulating PSD95 in a PTZ-Induced Epileptic Mouse Model.
Antimony-induced hippocampal neuronal impairment through ferroptosis activation from NCOA4-mediated ferritinophagy.
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model.
PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Astragalin-functionalized ultrasmall nanoparticles modulate the complement pathway to inhibit microglial synaptic phagocytosis for reducing anesthetic neurotoxicity.
Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress-regulated neuronal apoptosis in APP/PS1 transgenic mice.
Ginsenoside Rg1 improves autophagy dysfunction to ameliorate Alzheimer's disease via targeting FGR proto-oncogene.
Effects of intermittent theta burst stimulation on the inflammatory response and cerebral blood flow in promoting neurovascular repair after ischemic stroke.
Sirtuin-3 activation by honokiol attenuated anesthesia/surgery-induced cognitive impairment and neuronal ferroptosis via inhibiting mitochondrial GPX4 acetylation.
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Qinglongyi nanoparticles alleviate neuroinflammation and promote neuronal survival by inhibiting neuronal ferroptosis in intracerebral hemorrhage.
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Astrocytic modulation of GABA transmission in the VTA limits progression of anxiety- and depression-like behaviors in adult mice.
Targeting the RAGE-RIPK1 binding site attenuates diabetes-associated cognitive deficits.
Cerdulatinib Improves Sensorimotor Function and Memory Ability in Mice Suffering from Ischemic Stroke through Targeting Caspase-3-Dependent Apoptosis.
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitophagy.
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Costunolide normalizes neuroinflammation and improves neurogenesis deficits in a mouse model of depression through inhibiting microglial Akt/mTOR/NF-κB pathway.
Visualizing bulk autophagy in vivo by tagging endogenous LC3B.
Histone lactylation stimulated upregulation of PSMD14 alleviates neuron PANoptosis through deubiquitinating PKM2 to activate PINK1-mediated mitophagy after traumatic brain injury.
Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy.
Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization.
Tetramethylpyrazine exerts a neuroprotective effect in acute spinal cord injury by mitigating oxidative stress through PKD1: Multi-omics analysis and experimental validation.
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter.
Tyrosol ameliorates depressive-like behavior and hippocampal damage in perimenopausal depression rats by inhibiting oxidative stress and thyroid dysfunction.
SETD1B promotes brain cell ferroptosis in ischemic stroke mice via increasing H3K4me3 enrichment on the Tfrc promoter.
PGK1 Is Involved in the HIF-1 Signaling Pathway as a Hub Gene for Ferroptosis After Traumatic Brain Injury.
Biomimetic Nanomotors for Deep Ischemia Penetration and Ferroptosis Inhibition in Neuroprotective Therapy of Ischemic Stroke.
CHOP-Mediated Disruption of Hippocampal Synaptic Plasticity and Neuronal Activity Contributes to Chronic Pain-Related Cognitive Deficits.
PTPN2 dephosphorylates STAT3 to ameliorate anesthesia-induced cognitive decline in aged rats by altering the microglial phenotype and inhibiting inflammation.
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Can minor trauma cause asymptomatic cervical spinal cord compression leading to severe cervical spinal cord injury in rats?
Angong Niuhuang Pill pretreatment alleviates cerebral ischemia-reperfusion injury by inhibiting excessive autophagy through the SIRT1-H4K16ac axis.
Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme.
Mechanism of Buyang Huanwu Decoction mediating Cav1-regulated Wnt pathway to promote neural regeneration in cerebral ischemic mice.
Trehalose Inhibits ferroptosis Through Activating SIRT3/SOD2 Signaling Axis and Alleviates Brain Injury After Traumatic Brain Injury.
Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway.
NLRP3 inhibitor alleviates glycemic variability-induced cognitive impairment in aged rats with type 2 diabetes mellitus.
PGAM5 promotes RIPK1-PANoptosome activity by phosphorylating and activating RIPK1 to mediate PANoptosis after subarachnoid hemorrhage in rats.
Panaxadiol Attenuates Neuronal Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury via Regulation of the JAK3/STAT3/HIF-1α Signaling Pathway.
The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis.
Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.
Microglia-Derived Vitamin D Binding Protein Mediates Synaptic Damage and Induces Depression by Binding to the Neuronal Receptor Megalin.
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
Toona sinensis fruit polyphenols alleviate cerebral ischemia-reperfusion injury in rats by inhibiting MAPK signaling pathways and NLRP3 inflammasome/pyroptosis.
Impaired olfactory bulb neurogenesis mediated by Notch1 contributes to olfactory dysfunction in mice chronically exposed to methamphetamine.
Optineurin-facilitated axonal mitochondria delivery promotes neuroprotection and axon regeneration.
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Distinct Roles of Astrocytes and GABAergic Neurons in the Paraventricular Thalamic Nucleus in Modulating Diabetic Neuropathic Pain.
TREM2 deficiency aggravates neuroinflammatory response and cognitive impairment via disease-associated microglia in Parkinson's disease models.
Reprogramming activated astrocytes into GABAergic neurons to treat trigeminal neuralgia.
Dietary cholesterol impairs cognition via gut microbiota-derived deoxycholic acid in obese mice.
Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension.
Repetitive transcranial magnetic stimulation ameliorates myocardial injury in vascular dementia via renin-angiotensin system modulation.
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Biliverdin alleviates cerebral ischemia-reperfusion injury by regulating the P4hb/MAPK/mTOR pathway to inhibit autophagy.
Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity.
Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia.
Remote Ischemic Conditioning Attenuates Apoptosis, the Inflammatory Response, and Reperfusion Injury in Ischemic-Stroke Model Rats via the ELA-Apelin-APJ System.
Effect of the DPP4 Inhibitor Sitagliptin on Ferroptosis in Epilepsy.
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
In vitro axotomy models regulated by ROCK inhibitor for studying neuroregeneration and growth cone morphology.
An Elongator mouse model of ALS spotlights TDP-43 in the motor neuron nucleolus.
Charting the spatial transcriptome of the human cerebral cortex at single-cell resolution.
Gut microbiota's role in high-altitude cognitive impairment: the therapeutic potential of Clostridium sp. supplementation.
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson's Disease.
Transcription factor AP-2 Beta, a potential target of repetitive Transspinal magnetic stimulation in spinal cord injury treatment, reduced inflammation and alleviated spinal cord injury.
Intravenous tenecteplase bridging reperfusion ameliorates cerebral ischemia/reperfusion injury by improving microvascular circulation in rats.
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability.
Macrophage migration inhibitory factor in the mouse hippocampus promotes neuroinflammation and cognitive dysfunction following anesthesia and surgery.
Citrus medica L. essential oil improves anxiety-like behaviors accompanied by fatigue through α7-nAChR receptor-mediated neuroprotection effects.
Electroacupuncture Ameliorates Chronic Inflammatory Pain and Depression Comorbidity by Inhibiting Nrf2-Mediated Ferroptosis in Hippocampal Neurons.
Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.
Transient receptor potential vanilloid 4 blockage attenuates pyroptosis in hippocampus of mice following pilocarpine‑induced status epilepticus.
Effects of electroacupuncture per-conditioning at Huantiao on motor function recovery in acute cerebral ischemia mice.
Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis.
Shenfu Injection Mediated NLRP3/Caspase 1 Through (R)-Norcoclaurinee Alleviates Sepsis-Induced Cognitive Dysfunction.
APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases.
Microglial adenosine A(2A) receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.
Comparative analysis of two independent Myh6-Cre transgenic mouse lines.
E3 ubiquitin ligase MARCH1 reduces inflammation and pyroptosis in cerebral ischemia-reperfusion injury via PCSK9 downregulation.
Elucidating the molecular mechanisms behind the therapeutic impact of median nerve stimulation on cognitive dysfunction post-traumatic brain injury.
Therapeutic effect of nicotinamide mononucleotide on Alzheimer's disease through activating autophagy and anti-oxidative stress.
Withaferin A protects against epilepsy by promoting LCN2-mediated astrocyte polarization to stopping neuronal ferroptosis.
Oxytocin Protects Nigrostriatal Dopamine Signal via Activating GABAergic Circuit in the MPTP-Induced Parkinson's Disease Model.
AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice.
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures.
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice.
Ferroptosis contributes to diabetes-induced visual pathway neuronal damage via iron accumulation and GPX4 inactivation.
Curcumin attenuated neuroinflammation via the TLR4/MyD88/NF-κB signaling way in the juvenile rat hippocampus following kainic acid-induced epileptic seizures.
The Activation of PKM2 Induces Pyroptosis in Hippocampal Neurons via the NLRP3/Caspase-1/GSDMD Pathway in Neonatal Rats With Hypoxic-Ischemic Brain Injury.
Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study.
Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice.
Avicularin Treatment Ameliorates Ischemic Stroke Damage by Regulating Microglia Polarization and its Exosomes via the NLRP3 Pathway.
Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage.
Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia.
The effect of repetitive magnetic stimulation on neuronal apoptosis and PI3K/Akt protein expression in rats with incomplete spinal cord injury.
TRIM21-mediated ubiquitination of PLIN2 regulates neuronal lipid droplet accumulation after acute spinal cord injury.
Neuroprotective effects of mesenchymal stromal cells in mouse models of Alzheimer's Disease: The Mediating role of gut microbes and their metabolites via the Microbiome-Gut-Brain axis.
RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway.
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Abnormal hippocampal neurogenesis and impaired social recognition memory in two neurodevelopmental models of schizophrenia.
Neuronostatin regulates neuronal function and energetic metabolism in Alzheimer's disease in a GPR107-dependent manner.
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
Chronic stress induces Alzheimer's disease-like pathologies through DNA damage-Chk1-CIP2A signaling.
Pin1 Downregulation Is Involved in Excess Retinoic Acid-Induced Failure of Neural Tube Closure.
Dl-3-n-Butylphthalide Alleviates Secondary Brain Damage and Improves Working Memory After Stroke in Cynomolgus Monkeys.
Role of an interdependent Wnt, GSK3-β/β-catenin and HB-EGF/EGFR mechanism in arsenic-induced hippocampal neurotoxicity in adult mice.
CD8(+) T cell infiltration and proliferation in the brainstem during experimental cerebral malaria.
Enhanced axon outgrowth of spinal motor neurons in co-culturing with dorsal root ganglions antagonizes the growth inhibitory environment.
Novel perfluorocarbon-based oxygenation therapy alleviates Post-SAH hypoxic brain injury by inhibiting HIF-1α.
Physical and social environmental enrichment alleviate ferroptosis and inflammation with inhibition of TLR4/MyD88/p38MAPK pathway in chronic cerebral hypoperfusion rats.
Oxidative stress and mitochondrial dysfunction in brain of vinclozolin exposed animals.
Overexpression of forebrain PTP1B leads to synaptic and cognitive impairments in obesity.
Mechanism of Dendrobium Nobile Polysaccharide Inhibition of Ferroptosis in Rats with Spinal Cord Injury.
Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons.
Prenatal diesel exhaust exposure alters hippocampal synaptic plasticity in offspring.
PTPRO inhibition ameliorates spinal cord injury through shifting microglial M1/M2 polarization via the NF-κB/STAT6 signaling pathway.
Effects of a novel regimen of repetitive transcranial magnetic stimulation (rTMS) on neural remodeling and motor function in adult male mice with ischemic stroke.
Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition.
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy.
Development of adenoviral vectors that transduce Purkinje cells and other cerebellar cell-types in the cerebellum of a humanized mouse model.
Intestinal microbiota via NLRP3 inflammasome dependent neuronal pyroptosis mediates anxiety-like behaviour in mice exposed to 3.5 GHz radiofrequency radiation.
Ablated Sonic Hedgehog Signaling in the Dentate Gyrus of the Dorsal and Ventral Hippocampus Impairs Hippocampal-Dependent Memory Tasks and Emotion in a Rat Model of Depression.
Augmentation of functional recovery via ROCK/PI3K/AKT pathway by Fasudil Hydrochloride in a rat sciatic nerve transection model.
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice.
The suppressive effect of the specific KCC2 modulator CLP290 on seizure in mice.
Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury.
CDK5-USP30 signaling pathway regulates MAVS-mediated inflammation via suppressing mitophagy in MPTP/MPP(+) PD model.
Melatonin Exerts an Anti-Panoptoic Role in Spinal Cord Ischemia-Reperfusion Injured Rats.
Activation of G protein-coupled receptor 39 alleviates neuropathic pain and chronic inflammation.
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Selective homing of brain-derived reconstituted lipid nanoparticles to cerebral ischemic area enables improved ischemic stroke treatment.
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Acacetin inhibits activation of microglia to improve neuroinflammation after subarachnoid hemorrhage through the PERK signaling pathway mediated autophagy.
A circRNA ceRNA network involved in cognitive dysfunction after chronic cerebral hypoperfusion.
Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke.
Increased Expression of K(Na)1.2 Channel by MAPK Pathway Regulates Neuronal Activity Following Traumatic Brain Injury.
Tangeretin Attenuates Cerebral Ischemia-Reperfusion-Induced Neuronal Pyroptosis by Inhibiting AIM2 Inflammasome Activation via Regulating NRF2.
Loss of Slc39a12 in hippocampal neurons is responsible for anxiety-like behavior caused by temporomandibular joint osteoarthritis.
TsMS combined with EA promotes functional recovery and axonal regeneration via mediating the miR-539-5p/Sema3A/PlexinA1 signalling axis in sciatic nerve-injured rats.
The Primary Cilium and its Hedgehog Signaling in Nociceptors Contribute to Inflammatory and Neuropathic Pain.
The role of ApoE in fatty acid transport from neurons to astrocytes under ischemia/hypoxia conditions.
The compensatory increase of Gli-similar 3 inhibited neuronal apoptosis through regulating Mps one binder kinase activator 1b (MOB1b): a possible strategy for the functional recovery after spinal cord injury.
Eriocalyxin B alleviated ischemic cerebral injury by limiting microglia-mediated excessive neuroinflammation in mice.
Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing.
Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss.
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.
Tetramethylpyrazine alleviates ferroptosis and promotes functional recovery in spinal cord injury by regulating GPX4/ACSL4.
Peimine promotes microglial polarization to the M2 phenotype to attenuate drug-resistant epilepsy through suppressing the TLR4/NF-κB/HIF-1α signaling pathway in a rat model and in BV-2 microglia.
Selenoprotein H mediates low selenium-related cognitive decline through impaired oligodendrocyte myelination with disrupted hippocampal lipid metabolism in female mice.
Inhibition of neuronal pentraxin 2 relieved epileptic seizure via reducing GluA1 phosphorylation.
SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy.
Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a.
Benefits of Puerarin on Metabolic Syndrome and Its Associated Cardiovascular Diseases in Rats Fed a High-Fat/High-Sucrose Diet.
GSDMD/Drp1 signaling pathway mediates hippocampal synaptic damage and neural oscillation abnormalities in a mouse model of sepsis-associated encephalopathy.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.
Lateral septal nucleus, dorsal part, and dentate gyrus are necessary for spatial and object recognition memory, respectively, in mice.
Chaihu-Longgu-Muli decoction improves sleep disorders by restoring orexin-A function in CKD mice.
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
2-Deoxyglucose alleviates migraine-related behaviors by modulating microglial inflammatory factors in experimental model of migraine.
Adipose transplantation improves olfactory function and neurogenesis via PKCα-involved lipid metabolism in Seipin Knockout mice.
Purified Serum IgG from a Patient with Anti-IgLON5 Antibody Cause Long-Term Movement Disorders with Impaired Dopaminergic Pathways in Mice.
Telaprevir Improves Memory and Cognition in Mice Suffering Ischemic Stroke via Targeting MALT1-Mediated Calcium Overload and Necroptosis.
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Protocol for fine casting, imaging, and analysis of murine vascular networks with VALID.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Lycium barbarum glycopeptide alleviates neuroinflammation in spinal cord injury via modulating docosahexaenoic acid to inhibiting MAPKs/NF-kB and pyroptosis pathways.
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
The role of EndophilinA1 in chronic unpredicted mild stress-induced depression model mice.
Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation.
Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.
The neuroprotective effect of dl-3-n-butylphthalide on the brain with experimental intracerebral hemorrhage.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Proinflammatory activation of microglia in the cerebellum hyperexcites Purkinje cells to trigger ataxia.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Involvement of Mrgprd-expressing nociceptors-recruited spinal mechanisms in nerve injury-induced mechanical allodynia.
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Downregulation of High mobility group box 2 relieves spinal cord injury by inhibiting microglia-mediated neuroinflammation.
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
Activation of metabotropic glutamate receptor 1 regulates hippocampal CA1 region excitability in rats with status epilepticus by suppressing the HCN1 channel.
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Activation of the High-Affinity Choline Transporter 1 in the Spinal Cord Relieves Stress-Induced Hyperalgesia.
Hydrogen peroxide signaling modulates neuronal differentiation via microglial polarization and Wnt/β-catenin pathway.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
miR-10a induces inflammatory responses in epileptic hippocampal neurons of rats via PI3K/Akt/mTOR signaling pathway.
PACAP6-38 improves nitroglycerin-induced central sensitization by modulating synaptic plasticity at the trigeminal nucleus caudalis in a male rat model of chronic migraine.
SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
Role of the blood-spinal cord barrier: An adheren junction regulation mechanism that promotes chronic postsurgical pain.
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
A versatile vessel casting method for fine mapping of vascular networks using a hydrogel-based lipophilic dye solution.
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Intracerebral Hemorrhage-Induced Brain Injury: the Role of Lysosomal-Associated Transmembrane Protein 5.
Exercise ameliorates anxious behavior and promotes neuroprotection through osteocalcin in VCD-induced menopausal mice.
The NR2B-targeted intervention alleviates the neuronal injuries at the sub-acute stage of cerebral ischemia: an exploration of stage-dependent strategy against ischemic insults.
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Debris generated by laser and/or balloon cause cerebral infarction with different severity.
Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury.
Melatonin Protects Injured Spinal Cord Neurons From Apoptosis by Inhibiting Mitochondrial Damage via the SIRT1/Drp1 Signaling Pathway.
Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice.
Knockdown of NADPH oxidase 4 reduces mitochondrial oxidative stress and neuronal pyroptosis following intracerebral hemorrhage.
Dynamic Measurements of Cerebral Blood Flow Responses to Cortical Spreading Depolarization in the Murine Endovascular Perforation Subarachnoid Hemorrhage Model.
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice.
LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis.
GLP-1R agonist liraglutide attenuates pain hypersensitivity by stimulating IL-10 release in a nitroglycerin-induced chronic migraine mouse model.
GABA(B) Receptor Activation Attenuates Neuronal Pyroptosis in Post-cardiac Arrest Brain Injury.
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model.
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction.
Lactobacillus casei SYF-08 Protects Against Pb-Induced Injury in Young Mice by Regulating Bile Acid Metabolism and Increasing Pb Excretion.
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Lysosomal-associated transmembrane protein 5 deficiency exacerbates cerebral ischemia/reperfusion injury.
Young plasma reverses anesthesia and surgery-induced cognitive impairment in aged rats by modulating hippocampal synaptic plasticity.
Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer's disease risk.
Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α-Syn and tau fragments.
Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity.
Acute Administration of Metformin Protects Against Neuronal Apoptosis Induced by Cerebral Ischemia-Reperfusion Injury via Regulation of the AMPK/CREB/BDNF Pathway.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Ventrolateral Periaqueductal Gray Astrocytes Regulate Nociceptive Sensation and Emotional Motivation in Diabetic Neuropathic Pain.
Transfer of neuron-derived α-synuclein to astrocytes induces neuroinflammation and blood-brain barrier damage after methamphetamine exposure: Involving the regulation of nuclear receptor-associated protein 1.
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
C1q and SRPX2 regulate microglia mediated synapse elimination during early development in the visual thalamus but not the visual cortex.
PDK4 Decrease Neuronal Apoptosis via Inhibiting ROS-ASK1/P38 Pathway in Early Brain Injury After Subarachnoid Hemorrhage.
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation.
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice.
Icariin attenuates ischaemic stroke through suppressing inflammation mediated by endoplasmic reticulum stress signalling pathway in rats.
Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment.
High Expression of PDK4 Could Play a Potentially Protective Role by Attenuating Oxidative Stress after Subarachnoid Hemorrhage.
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
The decreased expression of miR-429 in plasma exosomes after spinal cord injury inhibits neuronal apoptosis by mediating the PTEN/PI3K/Akt pathway.
Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice.
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Anatomical and behavioral outcomes following a graded hemi-contusive cervical spinal cord injury model in mice.
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Caveolin-1 suppresses hippocampal neuron apoptosis via the regulation of HIF1α in hypoxia in naked mole-rats.
Identification and expression profile of novel STAND gene Nwd2 in the mouse central nervous system.
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain.
Astrocytic CD24 Protects Neuron from Recombinant High-Mobility Group Box 1 Protein(rHMGB1)-Elicited Neuronal Injury.
Single-atom nanozymes catalytically surpassing naturally occurring enzymes as sustained stitching for brain trauma.
Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation.
FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model.
High altitude is associated with pTau deposition, neuroinflammation, and myelin loss.
GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.
Homoharringtonine Inhibits Alzheimer's Disease Progression by Reducing Neuroinflammation via STAT3 Signaling in APP/PS1 Mice.
Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression.
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques.
Deficits in N-Methyl-D-Aspartate Receptor Function and Synaptic Plasticity in Hippocampal CA1 in APP/PS1 Mouse Model of Alzheimer's Disease.
Yi-Zhi-Fang-Dai Formula Exerts Neuroprotective Effects Against Pyroptosis and Blood-Brain Barrier-Glymphatic Dysfunctions to Prevent Amyloid-Beta Acute Accumulation After Cerebral Ischemia and Reperfusion in Rats.
Integrated Bioinformatics Analysis of Potential mRNA and miRNA Regulatory Networks in Mice With Ischemic Stroke Treated by Electroacupuncture.
Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior.
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Sodium alginate/collagen/stromal cell-derived factor-1 neural scaffold loaded with BMSCs promotes neurological function recovery after traumatic brain injury.
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Bifidobacterium adolescentis regulates catalase activity and host metabolism and improves healthspan and lifespan in multiple species.
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Huntingtin silencing delays onset and slows progression of Huntington's disease: a biomarker study.
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Nuclear PTEN deficiency and heterozygous PTEN loss have distinct impacts on brain and lymph node size.
Tak1 in the astrocytes of mediobasal hypothalamus regulates anxiety-like behavior in mice.
Blunted diurnal firing in lateral habenula projections to dorsal raphe nucleus and delayed photoentrainment in stress-susceptible mice.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature.
Congenital hypothyroidism impairs spine growth of dentate granule cells by downregulation of CaMKIV.
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cord.
Targeting senescent cells improves functional recovery after spinal cord injury.
Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation.
CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome.
Genetic deletion of Rnd3 suppresses apoptosis through NF‑κB signaling in the brain.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
An injury-induced serotonergic neuron subpopulation contributes to axon regrowth and function restoration after spinal cord injury in zebrafish.
Acute hypoxia elevates arginase 2 and induces polyamine stress response in zebrafish via evolutionarily conserved mechanism.
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Simvastatin-Ezetimibe enhances growth factor expression and attenuates neuron loss in the hippocampus in a model of intracerebral hemorrhage.
Brain network reorganization after targeted attack at a hub region.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis.
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury.
Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
HCN2 contributes to oxaliplatin-induced neuropathic pain by inducing spinal long-term potentiation via activation of NMDA receptor-mediated CaMKII signaling.
Let-7b-5p promotes electroacupuncture tolerance by downregulating Penk1 gene in CFA-induced inflammatory nociception rats.
miR-211-5p alleviates focal cerebral ischemia-reperfusion injury in rats by down-regulating the expression of COX2.
Glimepiride and glibenclamide have comparable efficacy in treating acute ischemic stroke in mice.
Expression of p16 and p21 in the frontal association cortex of ALS/MND brains suggests neuronal cell cycle dysregulation and astrocyte senescence in early stages of the disease.
The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury.
Sepsis induced cognitive impairments by disrupting hippocampal parvalbumin interneuron-mediated inhibitory network via a D4-receptor mechanism.
Positive regulation of the CREB phosphorylation via JNK-dependent pathway prevents antimony-induced neuronal apoptosis in PC12 cell and mice brain.
Baicalein Ameliorates Epilepsy Symptoms in a Pilocarpine-Induced Rat Model by Regulation of IGF1R.
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Overinhibition mediated by parvalbumin interneurons might contribute to depression-like behavior and working memory impairment induced by lipopolysaccharide challenge.
Decreased Netrin-1 and Correlated Th17/Tregs Balance Disorder in Aβ(1-42) Induced Alzheimer's Disease Model Rats.
Ellagic acid supports neuron by regulating astroglia Nrf2.
Antimony, a novel nerve poison, triggers neuronal autophagic death via reactive oxygen species-mediated inhibition of the protein kinase B/mammalian target of rapamycin pathway.
A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats.
Circular RNA TLK1 Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP.
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
DHEA Attenuates Microglial Activation via Induction of JMJD3 in Experimental Subarachnoid Haemorrhage.
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial biogenesis.
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility.
Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure.
Up-regulation of MCM3 Relates to Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats.
Human Umbilical Cord Mesenchymal Stem Cells Overexpressing Nerve Growth Factor Ameliorate Diabetic Cystopathy in Rats.
Gao F, Yang X, Yang Z, Yu D, Zhang B, Wang Y, Yao Z, Chen J, Liao Q, Li L, Hou B, Wang D, Zhang Y, Yan C
Research (Washington, D.C.) 2026;9:1032
Research (Washington, D.C.) 2026;9:1032
Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice.
Li T, Ye LQ, Liu HF, Chen XH, Wang Y, Chen ZM, Zheng Y, Zeng WX, Li SE, Wan L
Journal of inflammation research 2026;19:538350
Journal of inflammation research 2026;19:538350
Therapeutic relevance of an EU-GMP certified Cannabis sativa L. strain in a dual in vivo model of cognitive impairment and chronic neuropathic pain.
Costachescu I, Gogu RM, Stanciu GD, Solcan C, Horodincu L, Szilagyi A, Craciun VC, Ababei DC, Tamba BI
Frontiers in pharmacology 2026;17:1761426
Frontiers in pharmacology 2026;17:1761426
Adenosine A(2A) receptors regulate D(2)-type medium spiny neurons in the nucleus accumbens to mediate pain and depression comorbidity.
Zhou D, Yang X, Song L, Wu M, Zhang H, Cao JL, Min S
Frontiers in pharmacology 2026;17:1759544
Frontiers in pharmacology 2026;17:1759544
Gastrodia elata fermentation alleviates methamphetamine-induced neuroinflammation and anxiety- and depression-like behaviors by regulating the PI3K-AKT signaling pathway.
Liu Y, Yang H, Li H, Zhang S, Yang H, Luo Y, Hu T, Zhang Z, Peng X, Wang Y, Wei S, Xia B, Luo P
Frontiers in medicine 2026;13:1768944
Frontiers in medicine 2026;13:1768944
hUCMSC mitochondrial EVs confer neuroprotection after ischemia by Tom1l2-mediated mitochondrial fusion and Crls1-cardiolipin axis reprogramming.
Li Z, Zhu X, Liao W, Jiang R, Sang E, Zhu J, Sun G, Lu Z, Wang C, Jiang Y, Chen J, Gong P, Liu Q
Redox biology 2026 May;92:104106
Redox biology 2026 May;92:104106
Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
Gu L, Liu J, Shan X, Li S, Zheng M, Wang C, Tan Y, Zhuo X, Li Q, Yang W, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
Polygonatum Sibiricum polysaccharide ameliorates Alzheimer's disease by alleviating cuproptosis and activating the PI3K/AKT signaling pathway.
Wang S, Guo Y, Wang S, Wang Y, Huo S, Li M, Chen Q, Zhang L, Kuang H, Pan J, Liu Y
Journal of ethnopharmacology 2026 May 10;362:121359
Journal of ethnopharmacology 2026 May 10;362:121359
Decoding COPD-related cognitive impairment: The protective potential of YTHDF1.
Lu K, Qu Y, Shi R, Wu C, Xu T
Cellular signalling 2026 Mar;139:112311
Cellular signalling 2026 Mar;139:112311
Elevation of H(2)S Underlies Social Deficits in Environmental Factor Double-Hit Autism Model.
Ma H, Xu Q, Dong S, Guo M, Liu H, Wang T, Wang M, Wang Y, Wu S
Neuroscience bulletin 2026 Mar 23;
Neuroscience bulletin 2026 Mar 23;
Microglial NLRP3-dependent pyroptosis promotes cognitive dysfunction of diabetic encephalopathy by inhibiting adult hippocampal neurogenesis through the release of IL-1β.
Hua MY, Huang S, Zhuang ZY, Han XL, Liu XJ, Liang ZH, Lou NJ, Zheng FJ, Lv L, Zhuang XH, Yu SY, Chen SH
Acta pharmacologica Sinica 2026 Mar 20;
Acta pharmacologica Sinica 2026 Mar 20;
A Novel Polysaccharide (ZJP-2) from Wild Jujube Alleviates Oxidative Damage in Neural Stem Cells: Structural Features and Bioactivity.
Li S, Zhang Q, Liu J, Zhou X, Wang N, Chen H, Abudukelimu N, Dilixiati M, Zhang X, Liu X
Nutrients 2026 Mar 2;18(5)
Nutrients 2026 Mar 2;18(5)
Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.
Xiao T, Tao J, Tan J, Yi X, Wang Z, Duan X
Biomolecules 2026 Mar 11;16(3)
Biomolecules 2026 Mar 11;16(3)
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Duan Z, Yu C, Yu Q, Yang W, Zhang R, Ruan Q, Zhao Y, Yan S
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
M2 macrophage-derived exosomes delivering haptoglobin and interleukin-10 plasmids for synergistic therapy of intracerebral hemorrhage.
Wang K, Li J, He M, Wang L, Guo X, Zhou S
Bioactive materials 2026 Jun;60:510-526
Bioactive materials 2026 Jun;60:510-526
Indole metabolites produced by Lactobacillus acidophilus impedes bisphenol F- aryl hydrocarbon receptor interaction and ameliorates bisphenol F induced depression-like changes.
Hu M, Manglike A, Li X, Wei J, Lou X, Liu J, Tang Z, He W, Ji G, Wang W, Ma T, Gao R, Wang J
Journal of hazardous materials 2026 Jun 15;511:142150
Journal of hazardous materials 2026 Jun 15;511:142150
Spinal cord injury-derived exosomes exacerbate damage: miR-155-5p mediates inflammatory responses.
Fang Y, Chen W, Zhang Y, Yang Y, Wang S, Pei M, Zhou Y, Lin S, He H
Neural regeneration research 2026 Jun 1;21(6):2514-2522
Neural regeneration research 2026 Jun 1;21(6):2514-2522
ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model.
Dou S, Li Z, Zheng B, Ren Z, Wang H, Zuo Q, Fang F, Zhuang Y
International journal of molecular medicine 2026 Jan;57(1)
International journal of molecular medicine 2026 Jan;57(1)
Cycloastragenol protected hippocampal CA1 neurons by regulating redox homeostasis and alleviated cognitive impairment following cerebral ischemia-reperfusion.
Gao S, Zhu S, Qu T, Zou J, Yin L, Wang X, Yin X, Tong L, Li W
Brain research bulletin 2026 Jan;234:111689
Brain research bulletin 2026 Jan;234:111689
Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury.
Xu Q, Su J, Lei Q, Liu J, Wang J, Yang M, Song J, Chen H, Lu J
Brain research bulletin 2026 Jan;234:111687
Brain research bulletin 2026 Jan;234:111687
Electroacupuncture at Zusanli (ST36) alleviates paclitaxel-induced neuropathic pain in rats via regulating TLR4 signaling pathway in the spinal cord.
Wang MN, Zhou YX, Zhao YX, Tan JW, Sang X
Molecular pain 2026 Jan-Dec;22:17448069251413879
Molecular pain 2026 Jan-Dec;22:17448069251413879
Sennoside A ameliorates cognitive impairment by inhibiting USP14/ERK1/2 pathway in a mouse model of type 2 diabetes mellitus.
Wang L, He ZQ, Xu ZY, Qi YK, Sun YN
Behavioural brain research 2026 Jan 5;496:115853
Behavioural brain research 2026 Jan 5;496:115853
Sodium tanshinone IIA sulfonate alleviates neuroinflammation-induced damage to hippocampal neurons by activating SIRT1 in mice with sepsis-associated encephalopathy.
Song Y, Lin W, Yuan H, Hu H, Wu S, Lu Y, Li D, Jing L, Tu S, Zhu W
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120731
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120731
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Wu B, Wu J, Bai X, Zhou Q, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120479
Journal of ethnopharmacology 2026 Jan 10;354:120479
SATB1 Exhibits a Protective Role in HAmylin-Oligomer-Induced Neuronal Damage and Cognition Decline.
Xing Y, Zhang W, Yang Z, Qin X, Zhou T, Zhang N
CNS neuroscience & therapeutics 2026 Feb;32(2):e70781
CNS neuroscience & therapeutics 2026 Feb;32(2):e70781
hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
Chen Q, Zhai Q, Lin J, Huang Y, Li H, Zhang C, Yu Q, Sun T, Pan Y
The journal of headache and pain 2026 Feb 7;27(1)
The journal of headache and pain 2026 Feb 7;27(1)
ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.
Xiao J, Liu Y, Peng M, Ma J, Lei S, Chen Y, Liu S, Zhao X, Lu D, Sun Q
Alzheimer's research & therapy 2026 Feb 5;18(1)
Alzheimer's research & therapy 2026 Feb 5;18(1)
KANK4 Regulates CXCL16 Glycosylation Through TMEM260 to Modulate Microglial Activation in Sepsis-associated Encephalopathy.
Peng M, Tan S, Li A, Guo Q, Liu L
Inflammation 2026 Feb 28;49(1)
Inflammation 2026 Feb 28;49(1)
Glioblastoma-secreted C1QL1 orchestrates tumor microtube expansion and neural synaptic pruning to drive malignant synapse formation and recurrence.
Ding C, Dong J, Pan Z, Liu S, Song Q, Yang G, Peng Y, Xie C, Huang Z, Yao W, Wu M, Zhong Y, Zhang W, Zhang Y, Wang S, Ma W, Wang Y
Cancer discovery 2026 Feb 27;
Cancer discovery 2026 Feb 27;
Exploring the Role of TSPO-PET Imaging Among MRI-Negative Patients with Temporal Lobe Epilepsy: From the Perspective of Heterogeneity.
Chen Y, Wang J, Xu S, Wang Q, Mei S, Lu J, Wang Y, Lin H, Wu D, Chen L, Zuo C, Guan Y, Ge J, Wu X
Brain sciences 2026 Feb 22;16(2)
Brain sciences 2026 Feb 22;16(2)
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Protective Effects of Crocin Against Fluoride-Induced Neurotoxicity: Involvement of Wnt10b/β-Catenin Signaling.
Xu H, Chen X, Zhang Y, Yin F
Biological trace element research 2026 Feb 11;
Biological trace element research 2026 Feb 11;
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
Wen J, Tang H, Tian M, Wang L, Yang Q, Zhao Y, Li X, Ren Y, Wang J, Zhou L, Tan Y, Wu H, Cai X, Wang Y, Cao H, Xu J, Yang Q
Neural regeneration research 2026 Feb 1;21(2):756-768
Neural regeneration research 2026 Feb 1;21(2):756-768
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Guo J, Chi W, Zhang K, Huang Y, Zhang B, Guo X, Meng F
Cellular signalling 2026 Aug;144:112531
Cellular signalling 2026 Aug;144:112531
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Zhang J, Ding M, Luo L, Huang D, Li S, Chen S, Fan Y, Liu L, Xie H, Liu G, Yu K, Wu J, Xiao X, Wu Y
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Neural regeneration research 2026 Aug 1;21(8):3598-3608
ELAVL1 interacts with APP and promotes Aβ-induced apoptosis in Alzheimer's disease by activating Bcl-2/Bax signaling.
Fu J, Ding C, Li W, Lei J, Wang H, Meng L, Lin X, Chen W, Gao H
Experimental neurology 2026 Apr;398:115613
Experimental neurology 2026 Apr;398:115613
Bio-inspired spatiotemporal cascade reaction liposome for ferroptosis treatment following subarachnoid hemorrhage.
Peng Z, Li XJ, Xi YL, Zhu XL, Lu Y, Zhou Y, Yan HY, Wang J, Yang ZM, Hang CH, Ding YN, Wang JL, Li W
Materials today. Bio 2026 Apr;37:102979
Materials today. Bio 2026 Apr;37:102979
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Yang W, Su Y, Wang H, Liu P, Cheng P, Zhao H, He Y, Liu Y, Ma S, Guan F, Yao M
Materials today. Bio 2026 Apr;37:102913
Materials today. Bio 2026 Apr;37:102913
HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.
Feng Z, Liu Z, Tang S, Pan M, Zhu K, Liu Y, Wang C, Yao R, Wei X, Liu H
Journal of cellular and molecular medicine 2026 Apr;30(7):e71121
Journal of cellular and molecular medicine 2026 Apr;30(7):e71121
SERPINE1 drives neuropathic pain in a resiniferatoxin-induced model via AKT-mediated neuronal apoptosis.
Wang D, Xu L, Sun Y, Yue J, Li L
Brain research bulletin 2026 Apr;237:111820
Brain research bulletin 2026 Apr;237:111820
Targeting the ARRDC3-DRP1 Axis via hUMSC-Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury.
Ji R, Zhang Z, Liu Z, Yang K, Mao X, Chu M, Wang Y, Zhao J
Advanced healthcare materials 2026 Apr;15(14):e03803
Advanced healthcare materials 2026 Apr;15(14):e03803
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Tang J, Zhou S, Zhang Z, Duan B, Xu Y
Journal of molecular histology 2026 Apr 27;57(3)
Journal of molecular histology 2026 Apr 27;57(3)
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Xia J, Gao X, Yao J, Fei Y, Song D, Gu Z, Zheng G, Gu Y, Tu C
Biomaterials research 2025;29:0192
Biomaterials research 2025;29:0192
Pretreatment with a ketogenic diet inhibits mitochondrial damage in rat models of spinal cord injury via the PGC-1α/Sirt1/Nrf1 pathway.
Wang X, Lan W, Liao Y, Lu H
Iranian journal of basic medical sciences 2025;28(11):1516-1522
Iranian journal of basic medical sciences 2025;28(11):1516-1522
Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice.
Godse S, Zhou L, Sinha N, Salman M, Ishrat T, Kumar S
Experimental biology and medicine (Maywood, N.J.) 2025;250:10758
Experimental biology and medicine (Maywood, N.J.) 2025;250:10758
Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction.
Wu M, Li D, Qiu F, Nie H, Fang R, Zhong Z, Yang H, Lin X, Wang X, Wen H, Gong L, Meng P
PloS one 2025;20(3):e0316383
PloS one 2025;20(3):e0316383
Yttrium Oxide Nanoparticles Affect Both Cognitive and Memory Function by Disrupting Copper Output in Neuronal Cells in a Rat Model.
Zheng M, Chen Z, Xie J, Yang Q, Mo M, Chen L
International journal of nanomedicine 2025;20:5799-5815
International journal of nanomedicine 2025;20:5799-5815
Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury.
Yan L, Zhou X, Li Q, Hong H, Wu C, Gao YJ, Cui Z, Xu G
Frontiers in cellular neuroscience 2025;19:1622825
Frontiers in cellular neuroscience 2025;19:1622825
Bioinformatics analysis of electroacupuncture treatment for ischemic stroke: exploring transcriptional regulatory mechanisms mediated by super-enhancers.
Wu C, Wang Q, Xu Z, Deng C, Tang C
Frontiers in neuroscience 2025;19:1522466
Frontiers in neuroscience 2025;19:1522466
Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3β/NRF2 Pathway.
Duan M, Yu N, Liu J, Zhao Y, Zhang J, Song S, Wang S
Drug design, development and therapy 2025;19:111-128
Drug design, development and therapy 2025;19:111-128
The active metabolite of Epimedii Folium promotes hippocampal neurogenesis in APP/PS1 mice by alleviating mitochondrial dysfunction.
Bai JM, Li T, Di X, Yang JX, Cui ZQ, Min DY, Shen YF, Shan SY, Zhang YX, Shi YJ, Xu ZL, Dou DQ, Xiao HH
Frontiers in pharmacology 2025;16:1546256
Frontiers in pharmacology 2025;16:1546256
Exploring the potential anti-senescence effects of soybean-derived peptide Soymetide in mice hippocampal neurons via the Wnt/β-catenin pathway.
Garg A, Saroj J, Tiwari S, Das U, Shukla N, Ghosh JK, Bandyopadhyay S
Frontiers in pharmacology 2025;16:1510337
Frontiers in pharmacology 2025;16:1510337
Salvianolic acid B exerts cerebroprotective effects after traumatic brain injury via Nrf2-dependent antioxidant and anti-inflammatory cascades.
Wang D, Geng Y, Gu F, Zhuang Y, Lv H, He X, Yang H, Lu J
Experimental neurology 2025 Sep;391:115305
Experimental neurology 2025 Sep;391:115305
Senescent Microglia Mediate Neuroinflammation-Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1.
Liu K, Fan D, Wu HP, Hu XY, He QL, Wu XM, Shi CN, Yang JJ, Ji MH
Aging cell 2025 Sep;24(9):e70167
Aging cell 2025 Sep;24(9):e70167
Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis.
Luo J, Zhang X, Bharati L, Hua Z, Chen S, Dong Z
Biochemical pharmacology 2025 Sep;239:117054
Biochemical pharmacology 2025 Sep;239:117054
N-acetyltransferase 10 in the nucleus accumbens participates in methamphetamine-induced conditioned place preference and hyperlocomotion in mice.
Zeng ZH, Zhang LX, Li MQ, Wang XQ, Zou GJ, Yao JY, Li CQ, Cui YH, Li F
Neurochemistry international 2025 Sep;188:106017
Neurochemistry international 2025 Sep;188:106017
Protecting the brain from stroke: Huoxue Rongluo formula (HXRLF) targets ferroptosis for neuroprotection.
Ma Q, Luo L, Liao Y, Yang R, Ouyang X, Zhang Y, Yan S, Gong C, Liu L, Zhou D
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120329
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120329
Excessive mitochondrial stress response triggers neuronal injury through the persistent eIF2α phosphorylation in mice exposed to manganese.
Jia Y, He B, Chen K, Liu K, Yu C, Sun B, Ma Z, Xu B
Journal of hazardous materials 2025 Sep 15;496:139407
Journal of hazardous materials 2025 Sep 15;496:139407
Activation of CB1R alleviates autism spectrum disorder-like behavior and synaptic impairments.
Wang F, Liu Z, Hu J, Cheng Z, Liu S, Tian W, Zhang Y, Yang L, Liu T, Sun C, Zou M
Life sciences 2025 Sep 15;377:123797
Life sciences 2025 Sep 15;377:123797
Boosting 2-arachidonoylglycerol, but not N-acylethanolamine, ameliorates autism symptoms in VPA-exposed rats by modulating abnormal neuroinflammation.
Wang F, Gao Y, Liu Z, Cheng Z, Liu S, Zhang Y, Jiang Y, Zhang M, Yang X, Zou M, Sun C
Neuropharmacology 2025 Sep 15;276:110501
Neuropharmacology 2025 Sep 15;276:110501
Peripheral administration of the NAT10 inhibitor Remodelin prevents against Lipopolysaccharide induced depression in male mice.
Xu XF, Zhang AM, Hu T, Yang J, Wang M, Xu Y, Cao WY
European journal of pharmacology 2025 Sep 15;1003:177884
European journal of pharmacology 2025 Sep 15;1003:177884
EphB receptors modulate neuropathic pain via Ca(2+)/calpain/autophagy in spinal cord of mice.
Zhang T, Sun K, Huan X, Wang L
Neurological research 2025 Oct;47(10):919-931
Neurological research 2025 Oct;47(10):919-931
ETV5 improves ischemic stroke by targeting HACE1/Nrf2 axis to inhibit microglia M1 polarization and neuron pyroptosis.
Meng D, Su Q, Jia K, Jin M, Liu W, Yang S, Su Z
Biochemical pharmacology 2025 Oct;240:117057
Biochemical pharmacology 2025 Oct;240:117057
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage.
Liu X, Zeng L
Cellular signalling 2025 Oct;134:111941
Cellular signalling 2025 Oct;134:111941
Glutamatergic Neurons in the Cerebellar Lateral Nucleus Contribute to Motor Deficits Induced by Chronic Sleep Disturbance.
Zhu J, Qi WQ, Kong LX, Lin YM, Ding FF, Huang ZL, Qu WM
Brain sciences 2025 Oct 31;15(11)
Brain sciences 2025 Oct 31;15(11)
Neonatal sevoflurane anesthesia induces persistent cognitive deficits in mice through CypD-dependent mitochondrial impairment in parvalbumin interneurons.
Zhang X, Wang L, Zou X, Xu C, Qu W, Peng K, Hu X, Zhang L
Chemico-biological interactions 2025 Oct 22;420:111700
Chemico-biological interactions 2025 Oct 22;420:111700
Panax notoginseng Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis.
Zhao Y, Zhu F, Xie J, Wang Y, Matsabisa M, Tang M
Brain sciences 2025 Oct 15;15(10)
Brain sciences 2025 Oct 15;15(10)
Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's disease.
Song Z, Xie X, Chen Y, Zhang B, Li X, Yang Y, Mo W, Zhang J, Xu D
Immunity 2025 Oct 14;58(10):2574-2592.e9
Immunity 2025 Oct 14;58(10):2574-2592.e9
Pramipexole improves cognitive deficits and synaptic plasticity impairments in 3xTg-AD mice through enhancing autophagy.
Tuo C, Sui X, Cui C, Han F, Jiao J, Cai H, Wu M
Experimental neurology 2025 Oct 13;395:115503
Experimental neurology 2025 Oct 13;395:115503
Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke.
Guo S, Wang Z, Shi R, Huang P, Fang Y, Chen S, Huang M, Hu J, Lu Y, Xu X, Zou Y, Ruan L, Li X, Lin L, Wang X
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114080
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114080
CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.
Pang N, Liu Y, Yu S, Li Y, Shi K
Neuroscience 2025 Oct 1;584:356-366
Neuroscience 2025 Oct 1;584:356-366
Cassini: streamlined and scalable method for in situ profiling of RNA and protein.
Lapique N, Kim MT, Thom N, Nadaf NM, Pineda J, Macosko EZ
Nature communications 2025 Oct 1;16(1):8747
Nature communications 2025 Oct 1;16(1):8747
S100A11 mediates the protective effects of edaravone dexborneol on docetaxel-induced cognitive impairment in rats by inhibiting the MAPK signaling pathway.
Liu P, Jia J, Lu Y, Tang H, Gao C, Han S
Toxicology and applied pharmacology 2025 Nov;504:117504
Toxicology and applied pharmacology 2025 Nov;504:117504
Human Cortical Organoids with a Novel SCN2A Variant Exhibit Hyperexcitability and Differential Responses to Anti-Seizure Compounds.
Yang Y, Cai Y, Wang S, Wu X, Shao Z, Wang X, Ding J
Neuroscience bulletin 2025 Nov;41(11):2010-2024
Neuroscience bulletin 2025 Nov;41(11):2010-2024
Aerobic Exercise Training Exerts Neuroprotective Effects in Alzheimer's Disease Mice by Regulating Endoplasmic Reticulum Stress-Autophagy Pathway-Mediated Pyroptosis.
Wang Y, Sun X, He B, Yu S, Yu Y
CNS neuroscience & therapeutics 2025 Nov;31(11):e70620
CNS neuroscience & therapeutics 2025 Nov;31(11):e70620
Astrocyte-microglia crosstalk in the hippocampus mediates cognitive impairments induced by chronic intermittent hypoxia.
Wu ZH, Zhai MR, Wang YR, Ren L, Pan J, Xiao L, Liu YH
Neurobiology of disease 2025 Nov;216:107117
Neurobiology of disease 2025 Nov;216:107117
Transcranial direct current stimulation attenuates cerebral ischemia-reperfusion injury by inhibiting neuronal pyroptosis via Netrin-1.
Wang Y, Liu H, Li P, Zhang Z, He Y, Chen Y, Peng Y, Wang B, Jiang L, Li C, Zhu Q, Niu L
Neurochemistry international 2025 Nov;190:106041
Neurochemistry international 2025 Nov;190:106041
METTL3 modulates bone Cancer pain via m(6)A-dependent JAK2/STAT3 activation in spinal astrocytes.
Liu M, Yang L, Yan Z, Huang Y
Cellular signalling 2025 Nov;135:112046
Cellular signalling 2025 Nov;135:112046
Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance.
Liang YP, Zhang DY, Le DS, Liu L, Yang F, Sun SY, Lai GR, Zhang C, Zhao ML, Liao PS, Liu T, Wang B
Brain, behavior, and immunity 2025 Nov;130:106070
Brain, behavior, and immunity 2025 Nov;130:106070
Circulating Cathepsin D Exacerbates Injury-Induced Brain Damage by Promoting Neutrophil Infiltration Into the Brain.
Liang Y, Zhao D, Wu PF, Liang YQ, Zhang XW, Xing J, Sun X, An MX, Shi JX, Gao QH, Tian L, Sun HZ, Xue B, Jiang LB, Chen YH, Zhao WD
Journal of the American Heart Association 2025 Nov 4;14(21):e043416
Journal of the American Heart Association 2025 Nov 4;14(21):e043416
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Ma CS, Han B, Liu YX, Shi CK, Li DL, Guo JF, Bai M, Meng SC, Zhang LY, Duan MY, He MT
Molecular neurobiology 2025 Nov 29;63(1):219
Molecular neurobiology 2025 Nov 29;63(1):219
Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.
Shi J, Chen S, Wang J, Rastegar-Kashkooli Y, Fu P, Huang M, Zhang J, Wang J, Jiang C
Molecular neurobiology 2025 Nov 19;63(1):70
Molecular neurobiology 2025 Nov 19;63(1):70
Olfactory ensheathing cell transplantation alleviates cancer pain by inhibiting P2X7 receptor expression-mediated activation of microglia.
Zhang WJ, Liu JP, Xu YS, Zuo C, Liao JX, Zhu FQ, Hu JL
International journal of surgery (London, England) 2025 Nov 1;111(11):7727-7745
International journal of surgery (London, England) 2025 Nov 1;111(11):7727-7745
Genetic Ablation of Sarm1 Mitigates Disease Acceleration after Traumatic Brain Injury in the SOD1(G93A) Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
Dogan EO, Simonini SR, Bouley J, Weiss A, Brown RH Jr, Henninger N
Annals of neurology 2025 May;97(5):963-975
Annals of neurology 2025 May;97(5):963-975
Hydrogen sulfide improves depression-like behaviors in CUMS-induced mice by regulating autophagy.
Ling Z, Kong Q, He Z, Hao X, Liu R, Liu J, Wang Y, Liu J, Du W, Liu Y
Psychoneuroendocrinology 2025 May;175:107418
Psychoneuroendocrinology 2025 May;175:107418
Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN.
Jiang Y, Xiao H, Yang Y, Chen G, Zhang Y, Wu X, Zhang Q, Huang Q, Gao H, Han Y, Zhang A, Jiang D, Zheng L, Li Y, Gao Y
Cancer medicine 2025 May;14(9):e70953
Cancer medicine 2025 May;14(9):e70953
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
Wang M, Xia X, Li Y, Zhang K, Cheng X, Wen X, Zhao L, Guo X, Song F, Cheng A
Advanced healthcare materials 2025 May;14(13):e2500929
Advanced healthcare materials 2025 May;14(13):e2500929
PARP14 inhibits microglial activation via NNT to alleviate depressive-like behaviors in mice.
Yu X, Yang T, Wu D, Xu C, Li Z, Sun A, Gao S, Li H, Fan Z, Huang R
Brain, behavior, and immunity 2025 May;126:235-246
Brain, behavior, and immunity 2025 May;126:235-246
Rilmenidine attenuates intracerebral hemorrhage by regulating autophagy flux and apoptosis via the HO-1/Fe(2+)/ERK pathway.
Hua Q, Lu M, Li Z, Song P, Gao L, Zhou L, Zhang J, Cai Q
Neuroscience 2025 May 7;573:382-398
Neuroscience 2025 May 7;573:382-398
Paclitaxel alleviates spinal cord injury via activation of the Wnt/β-catenin signaling pathway.
Chen Z, Wo D, Wu C, Ma E, Peng J, Zhu W, Ren DN
Molecular medicine (Cambridge, Mass.) 2025 May 6;31(1):172
Molecular medicine (Cambridge, Mass.) 2025 May 6;31(1):172
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
Zou W, Kou L, Wang Y, Jin Z, Xiong N, Wang T, Xia Y
NPJ Parkinson's disease 2025 May 28;11(1):141
NPJ Parkinson's disease 2025 May 28;11(1):141
TREM2 deficiency exacerbates cognitive impairment by aggravating α-Synuclein-induced lysosomal dysfunction in Parkinson's disease.
Zhu B, Feng J, Liang X, Fu Z, Liao M, Deng T, Wang K, Xie J, Chi J, Yang L, Gao Y, Nie K, Wang L, Zhang P, Zhang Y
Cell death discovery 2025 May 20;11(1):243
Cell death discovery 2025 May 20;11(1):243
Tanshinone IIA Promotes Functional Recovery After Spinal Cord Injury by Inhibiting Neuron and Oligodendrocyte Ferroptosis Through the GPX4/ACSL4 Axis.
Xu L, Jiang G, Tan S, Ma Y, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
Neurochemical research 2025 May 16;50(3):167
Neurochemical research 2025 May 16;50(3):167
Region-specific Brain Targets Drive Circuit Formation and Maturation of Human Retinal Ganglion Cells.
Huang KC, Jeng HY, Abdulwahab Q, Cuevas VR, Shihabeddin E, Young C, Hernandez M, Meyer JS, Tran NM, Samuel MA
bioRxiv : the preprint server for biology 2025 May 10;
bioRxiv : the preprint server for biology 2025 May 10;
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
Yamada T, Ikeda A, Murata D, Wang H, Zhang C, Khare P, Adachi Y, Ito F, Quirós PM, Blackshaw S, López-Otín C, Langer T, Chan DC, Le A, Dawson VL, Dawson TM, Iijima M, Sesaki H
Nature 2025 Mar;639(8055):776-783
Nature 2025 Mar;639(8055):776-783
TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus.
Qi X, Chen X, Luo Q, Liu L, An D, Sha S, Du Y, Wu C, Chen L
Molecular neurobiology 2025 Mar;62(3):3615-3629
Molecular neurobiology 2025 Mar;62(3):3615-3629
Glial scarring limits recovery following decompressive surgery in rats with syringomyelia.
Cui S, Li J, Zhang C, Li Q, Jiang C, Wang X, Yu X, Li K, Feng Y, Jian F
Experimental neurology 2025 Mar;385:115113
Experimental neurology 2025 Mar;385:115113
Hydrogen Sulfide Sustained Release Donor Alleviates Spinal Cord Ischemia-Reperfusion-Induced Neuron Death by Inhibiting Ferritinophagy-Mediated Ferroptosis.
Xie L, He Q, Wu H, Shi W, Xiao X, Yu T
CNS neuroscience & therapeutics 2025 Mar;31(3):e70366
CNS neuroscience & therapeutics 2025 Mar;31(3):e70366
Elucidation of Dexmedetomidine-Induced Analgesic Tolerance Mechanisms in Neuropathic Pain With Modulation of SGK1, NR2A, and NR2B Expression via the Spinal SGK1/NF-κB Signalling Pathway.
Huikang W, Shiya C, Di P, Kiani FA, Hao L, Sha N, Xuan L, Abouelfetouh MM, Ahmed Z, Mingxing D, Yi D
Journal of cellular and molecular medicine 2025 Mar;29(6):e70372
Journal of cellular and molecular medicine 2025 Mar;29(6):e70372
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Tang H, Wen J, Wang L, Yang Q, Qin T, Ren Y, Zhao Y, Li C, Li J, Cao H, Xu J, Yang Q
Neurochemistry international 2025 Mar;184:105950
Neurochemistry international 2025 Mar;184:105950
Egln3 expression in microglia enhances the neuroinflammatory responses in Alzheimer's disease.
Guan J, Wu P, Liu M, Jiang C, Meng X, Wu X, Lu M, Fan Y, Gan L
Brain, behavior, and immunity 2025 Mar;125:21-32
Brain, behavior, and immunity 2025 Mar;125:21-32
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.
Yang H, Wang Y, Liu S, Zhang S, Chen Y, Ding J, Chen S, Zhu F, Xia B, Luo P, Liu Y
Neurotoxicology 2025 Mar;107:53-61
Neurotoxicology 2025 Mar;107:53-61
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction.
Jin G, Han W, Duan T, Xue Z, Song C, Xu Y, Yu M
Metabolic brain disease 2025 Mar 3;40(3):134
Metabolic brain disease 2025 Mar 3;40(3):134
PLGA-Encapsulated Elvitegravir and Curcumin Modulates ART Penetration, Oxidative Stress, and Inflammation.
Godse S, Zhou L, Sinha N, Mirzahosseini G, Kumar S
Brain sciences 2025 Mar 21;15(4)
Brain sciences 2025 Mar 21;15(4)
FKBP51 is Involved in Epileptic Seizure by Regulating PSD95 in a PTZ-Induced Epileptic Mouse Model.
Chen L, Cui W, Qin J, Zhu M, Zhang H, Yang J, Xu Z, Huang H
Journal of integrative neuroscience 2025 Mar 19;24(3):25710
Journal of integrative neuroscience 2025 Mar 19;24(3):25710
Antimony-induced hippocampal neuronal impairment through ferroptosis activation from NCOA4-mediated ferritinophagy.
Yu S, Qin Z, Chen Y, Wang F, Li Z, Huang R, Gao Z, Qu Y, Xue P, Luo Y, Wang X, Zhao X
Chemico-biological interactions 2025 Mar 1;409:111415
Chemico-biological interactions 2025 Mar 1;409:111415
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model.
Ding X, Chen C, Zhao H, Dai B, Ye L, Song T, Huang S, Wang J, You T
Neural regeneration research 2025 Mar 1;20(3):858-872
Neural regeneration research 2025 Mar 1;20(3):858-872
PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
Wang A, Zhang F, Zhang W, Gong J, Sun X
Experimental neurology 2025 Jun;388:115218
Experimental neurology 2025 Jun;388:115218
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Liu W, Zhu Y, Ye W, Xiong J, Wang H, Gao Y, Huang S, Zhang Y, Zhou X, Zhou X, Ge X, Cai W, Zheng X
Cell death and differentiation 2025 Jun;32(6):1041-1057
Cell death and differentiation 2025 Jun;32(6):1041-1057
Astragalin-functionalized ultrasmall nanoparticles modulate the complement pathway to inhibit microglial synaptic phagocytosis for reducing anesthetic neurotoxicity.
Wang G, Han Y, Peng K, Jiang Z, Wang T, Zheng Q, Li W, Xu H, Ji F, Li Z
Materials today. Bio 2025 Jun;32:101714
Materials today. Bio 2025 Jun;32:101714
Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress-regulated neuronal apoptosis in APP/PS1 transgenic mice.
Zhang N, Zhao Z, Chen X, Yao H, Zhu M, Ma S, Wang H, Yin X, Zhou Y, Zheng C, Li J, Pan J, Wang K, Yang B, Wang Y, Fan J, Gong Y, Liu R, Zeng J, Fan X, Shentu Y
Neuroprotection (Chichester, England) 2025 Jun;3(2):183-201
Neuroprotection (Chichester, England) 2025 Jun;3(2):183-201
Ginsenoside Rg1 improves autophagy dysfunction to ameliorate Alzheimer's disease via targeting FGR proto-oncogene.
Quan Q, Ma X, Feng J, Li W, Li X
Neuropeptides 2025 Jun;111:102514
Neuropeptides 2025 Jun;111:102514
Effects of intermittent theta burst stimulation on the inflammatory response and cerebral blood flow in promoting neurovascular repair after ischemic stroke.
Zhang J, Li S, Huang D, Fu J, Chen S, Ren N, Yang P, Song D, Bai X, Xie H, Liu G, Yu K, Ng SSM, Wu J, Xiao X, Wu Y
Molecular brain 2025 Jun 9;18(1):48
Molecular brain 2025 Jun 9;18(1):48
Sirtuin-3 activation by honokiol attenuated anesthesia/surgery-induced cognitive impairment and neuronal ferroptosis via inhibiting mitochondrial GPX4 acetylation.
Zeng L, Hu P, Wang X, Ding X, Wang Q, Luo L, Zhang Y, Li M, Zhao Y, Li S, Luo A
Journal of nanobiotechnology 2025 Jun 4;23(1):414
Journal of nanobiotechnology 2025 Jun 4;23(1):414
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Xiao W, Yang Y, Bai L, Yang P, Li R, Yang D, Li F, Quan L, Liang Q, Yan Y, Qi T, Liang F
Journal of neuroinflammation 2025 Jun 28;22(1):168
Journal of neuroinflammation 2025 Jun 28;22(1):168
Qinglongyi nanoparticles alleviate neuroinflammation and promote neuronal survival by inhibiting neuronal ferroptosis in intracerebral hemorrhage.
Yan T, Kang G, Meng Y, Zhang L, Jiang Q, Shen N, Li H, Xu M, Yu L, Ni G, Ma H, Guo F, Cui Y, Che F
International immunopharmacology 2025 Jun 26;159:114945
International immunopharmacology 2025 Jun 26;159:114945
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Hou D, Hu Y, Li H, Yang G
International immunopharmacology 2025 Jun 26;159:114882
International immunopharmacology 2025 Jun 26;159:114882
Astrocytic modulation of GABA transmission in the VTA limits progression of anxiety- and depression-like behaviors in adult mice.
Du J, Diao H, Xu Y, Li X, Yuan C, Nie L, Zhang H, Li J, Wang Y
Cell reports 2025 Jun 24;44(6):115824
Cell reports 2025 Jun 24;44(6):115824
Targeting the RAGE-RIPK1 binding site attenuates diabetes-associated cognitive deficits.
Gao L, Wu S, Hu B, Zhang Q, Wu Y, Li H, Qian Y, Huang C, Wen X, Li H, Cheng A, Song Y, Ying C, Zhou X
Journal of neuroinflammation 2025 Jun 21;22(1):162
Journal of neuroinflammation 2025 Jun 21;22(1):162
Cerdulatinib Improves Sensorimotor Function and Memory Ability in Mice Suffering from Ischemic Stroke through Targeting Caspase-3-Dependent Apoptosis.
Zhang YY, Li RF, Tian J, Peng J, Luo XJ
ACS chemical neuroscience 2025 Jun 18;16(12):2248-2259
ACS chemical neuroscience 2025 Jun 18;16(12):2248-2259
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitophagy.
Li Y, Shang J, Zhang H, Lu Y, Zhao Y, Wang Y, Yan X, Zhang J
ACS chemical neuroscience 2025 Jun 18;16(12):2208-2216
ACS chemical neuroscience 2025 Jun 18;16(12):2208-2216
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.
Fu G, Li T, Zhao Y, Zhang S, Xue X, Yang Y, Li T, Luo S, Yue G, Lei T
Chinese medicine 2025 Jun 16;20(1):87
Chinese medicine 2025 Jun 16;20(1):87
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Zhang Q, Huang J, Chen X, Li L, Chen L, Zhou X, Zhao X, Liu M, Zhao W, Yan J, Wang Y, Su Y, Liu Y, Xu S, Zeng W
ACS nano 2025 Jun 10;19(22):20452-20471
ACS nano 2025 Jun 10;19(22):20452-20471
Costunolide normalizes neuroinflammation and improves neurogenesis deficits in a mouse model of depression through inhibiting microglial Akt/mTOR/NF-κB pathway.
Zhang SQ, Deng Q, Tian C, Zhao HH, Yang LY, Cheng XW, Wang GP, Liu D
Acta pharmacologica Sinica 2025 Jul;46(7):1864-1876
Acta pharmacologica Sinica 2025 Jul;46(7):1864-1876
Visualizing bulk autophagy in vivo by tagging endogenous LC3B.
Gao X, Xiong Y, Ma H, Zhou H, Liu W, Sun Q
Autophagy 2025 Jul;21(7):1591-1607
Autophagy 2025 Jul;21(7):1591-1607
Histone lactylation stimulated upregulation of PSMD14 alleviates neuron PANoptosis through deubiquitinating PKM2 to activate PINK1-mediated mitophagy after traumatic brain injury.
Xu L, Ye Y, Gu W, Xu X, Chen N, Zhang L, Cai W, Hu J, Wang T, Chao H, Tu Y, Ji J
Autophagy 2025 Jul;21(7):1473-1491
Autophagy 2025 Jul;21(7):1473-1491
Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy.
Zeng QQ, Qi Y, Yu H, Xu Y, Chen JX, Zheng YW, Zhang GF, Zhang QL, Zheng YH, Guo J, Zhao ZH, Wang FS, Jin GL
Journal of neuroinflammation 2025 Jul 9;22(1):176
Journal of neuroinflammation 2025 Jul 9;22(1):176
Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization.
Wen J, Tang H, Wang L, Yang Q, Zhao Y, Ren Y, Qin T, Li X, Xu J, Jia G, Yang Q
BMC medicine 2025 Jul 7;23(1):407
BMC medicine 2025 Jul 7;23(1):407
Tetramethylpyrazine exerts a neuroprotective effect in acute spinal cord injury by mitigating oxidative stress through PKD1: Multi-omics analysis and experimental validation.
Huo L, Zhao Y, Bai H, Liu G, Yang X, Li X, Zhou Y, Yue J, Zhou Z, Xu L, Deng B, Li J, Mu X
European journal of pharmacology 2025 Jul 5;998:177514
European journal of pharmacology 2025 Jul 5;998:177514
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.
Ma L, Gao Y, Chen J, Hai D, Yu J, Tang S, Liu N, Liu Y
Journal of ethnopharmacology 2025 Jul 24;351:120072
Journal of ethnopharmacology 2025 Jul 24;351:120072
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Yao L, Jing R, Wang C, Wang Y, Li X, Wu X, Wang Y, Liu L, Mu L, Liu P, Hu Y
Journal of ethnopharmacology 2025 Jul 24;351:120011
Journal of ethnopharmacology 2025 Jul 24;351:120011
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Tian S, Wu L, Zheng H, Cheng Z, Liu J, Liu M, Yu X, Tu J, Wu W
The journal of headache and pain 2025 Jul 22;26(1):165
The journal of headache and pain 2025 Jul 22;26(1):165
Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter.
Ren Y, Wang Z, Wei Z, Zhuang R, Zhang Y, Liu X, Jiang C, Liu X, Yun Y, Li Y, Hong W, Wang T
iScience 2025 Jul 18;28(7):112931
iScience 2025 Jul 18;28(7):112931
Tyrosol ameliorates depressive-like behavior and hippocampal damage in perimenopausal depression rats by inhibiting oxidative stress and thyroid dysfunction.
Sun X, Zhao M, Wang X, Sun Y, Li J, Zhang Y, Zhang Y, Feng X
Neuroscience letters 2025 Jul 13;859-861:138266
Neuroscience letters 2025 Jul 13;859-861:138266
SETD1B promotes brain cell ferroptosis in ischemic stroke mice via increasing H3K4me3 enrichment on the Tfrc promoter.
Wang L, Liu HR, Liu HQ, Li XS, Tang TT, Wang KJ, Wei GR, Tian J, Zhang YY, Luo XJ
Life sciences 2025 Jul 1;372:123625
Life sciences 2025 Jul 1;372:123625
PGK1 Is Involved in the HIF-1 Signaling Pathway as a Hub Gene for Ferroptosis After Traumatic Brain Injury.
Wang Z, Tian J, Wang L, Yan H, Feng S, Zhang Y
Molecular neurobiology 2025 Jan;62(1):233-245
Molecular neurobiology 2025 Jan;62(1):233-245
Biomimetic Nanomotors for Deep Ischemia Penetration and Ferroptosis Inhibition in Neuroprotective Therapy of Ischemic Stroke.
Wang R, Nie W, Yan X, Luo K, Zhang Q, Wang T, Lu E, Chen Y, Luo Y, Zhang Z, Wang H, Zhao J, Sha X
Advanced materials (Deerfield Beach, Fla.) 2025 Jan;37(3):e2409176
Advanced materials (Deerfield Beach, Fla.) 2025 Jan;37(3):e2409176
CHOP-Mediated Disruption of Hippocampal Synaptic Plasticity and Neuronal Activity Contributes to Chronic Pain-Related Cognitive Deficits.
Meng Q, Su S, Lei L, Zhang Y, Duan J, Ren X, Song Y, Hu X, Chen S, Zang W, Zhang Z, Cao J
CNS neuroscience & therapeutics 2025 Jan;31(1):e70160
CNS neuroscience & therapeutics 2025 Jan;31(1):e70160
PTPN2 dephosphorylates STAT3 to ameliorate anesthesia-induced cognitive decline in aged rats by altering the microglial phenotype and inhibiting inflammation.
Zhao X, Wang X, Xu Z, Chang X, Tian Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167545
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167545
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Chi X, Yin S, Sun Y, Kou L, Zou W, Wang Y, Jin Z, Wang T, Xia Y
Brain, behavior, and immunity 2025 Jan;123:229-243
Brain, behavior, and immunity 2025 Jan;123:229-243
Can minor trauma cause asymptomatic cervical spinal cord compression leading to severe cervical spinal cord injury in rats?
Xu L, Wang T, Cao Z, Gao Y, Jiang G, Ma Y, Song J, Yang Y, Yu X
Neuroreport 2025 Jan 8;36(1):1-10
Neuroreport 2025 Jan 8;36(1):1-10
Angong Niuhuang Pill pretreatment alleviates cerebral ischemia-reperfusion injury by inhibiting excessive autophagy through the SIRT1-H4K16ac axis.
Wang L, Hou J, Xu H, Cai Q, Tian L, Li X, Zhang J, Yang H
Journal of ethnopharmacology 2025 Jan 31;340:119214
Journal of ethnopharmacology 2025 Jan 31;340:119214
Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme.
Zhang Y, Duan W, Chen L, Chen J, Xu W, Fan Q, Li S, Liu Y, Wang S, He Q, Li X, Huang Y, Peng H, Zhao J, Zhang Q, Qiu Z, Shao Z, Zhang B, Wang Y, Tian Y, Shu Y, Qin Z, Chi Y
Neuron 2025 Jan 22;113(2):225-243.e10
Neuron 2025 Jan 22;113(2):225-243.e10
Mechanism of Buyang Huanwu Decoction mediating Cav1-regulated Wnt pathway to promote neural regeneration in cerebral ischemic mice.
OuYang Y, Yi J, Chen B, Zeng F, Chen X, Yang H, Xu Y, Liu Z, Ning W, Liu B
Journal of ethnopharmacology 2025 Jan 13;339:119121
Journal of ethnopharmacology 2025 Jan 13;339:119121
Trehalose Inhibits ferroptosis Through Activating SIRT3/SOD2 Signaling Axis and Alleviates Brain Injury After Traumatic Brain Injury.
Mu Z, Sun Z, Wu S, Yang J, Wang P, Zhao X
Neurochemical research 2025 Jan 11;50(1):78
Neurochemical research 2025 Jan 11;50(1):78
Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway.
Zhan Y, Huang J, Tang X, Du B, Yang B
Journal of ethnopharmacology 2025 Jan 10;336:118741
Journal of ethnopharmacology 2025 Jan 10;336:118741
NLRP3 inhibitor alleviates glycemic variability-induced cognitive impairment in aged rats with type 2 diabetes mellitus.
Yang W, Si SC, Li J, Ma YX, Zhao H, Liu J
Molecular and cellular endocrinology 2025 Jan 1;595:112406
Molecular and cellular endocrinology 2025 Jan 1;595:112406
PGAM5 promotes RIPK1-PANoptosome activity by phosphorylating and activating RIPK1 to mediate PANoptosis after subarachnoid hemorrhage in rats.
Jiajia D, Wen Y, Enyan J, Xiaojian Z, Zhen F, Jia Z, Jikai W, Xiaoxin Y, Aihua L, Fangen K, Fei L
Experimental neurology 2025 Feb;384:115072
Experimental neurology 2025 Feb;384:115072
Panaxadiol Attenuates Neuronal Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury via Regulation of the JAK3/STAT3/HIF-1α Signaling Pathway.
Zhou J, Lei Y, Zhang S, Liu Y, Yi D
CNS neuroscience & therapeutics 2025 Feb;31(2):e70233
CNS neuroscience & therapeutics 2025 Feb;31(2):e70233
The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis.
He X, Hu M, Xu Y, Xia F, Tan Y, Wang Y, Xiang H, Wu H, Ji T, Xu Q, Wang L, Huang Z, Sun M, Wan Y, Cui P, Liang S, Pan Y, Xiao S, He Y, Song R, Yan J, Quan X, Wei Y, Hong C, Liao W, Li F, El-Omar E, Chen J, Qi X, Gao J, Zhou H
Nature medicine 2025 Feb;31(2):627-638
Nature medicine 2025 Feb;31(2):627-638
Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.
Wang W, Wang Y, Huang X, Wu P, Li L, Zhang Y, Chen Y, Chen Z, Li C, Zhou Y, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483
Microglia-Derived Vitamin D Binding Protein Mediates Synaptic Damage and Induces Depression by Binding to the Neuronal Receptor Megalin.
Kong Y, Zhang X, Li L, Zhao T, Huang Z, Zhang A, Sun Y, Jiao J, Zhang G, Liu M, Han Y, Yang L, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2410273
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2410273
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
He X, Deng B, Zhang C, Zhang G, Yang F, Zhu D, Yang Y, Ma B, Hu X, Wang Y, Kang X
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Toona sinensis fruit polyphenols alleviate cerebral ischemia-reperfusion injury in rats by inhibiting MAPK signaling pathways and NLRP3 inflammasome/pyroptosis.
Wang K, Zhao H, Chen J, Yan LL, Zhao B, Chen Y, Dong YY, Li ZC, He Z
Journal of ethnopharmacology 2025 Feb 27;342:119375
Journal of ethnopharmacology 2025 Feb 27;342:119375
Impaired olfactory bulb neurogenesis mediated by Notch1 contributes to olfactory dysfunction in mice chronically exposed to methamphetamine.
Gu C, Wang Z, Luo W, Ling H, Cui X, Deng T, Li K, Huang W, Xie Q, Tao B, Qi X, Peng X, Ding J, Qiu P
Cell biology and toxicology 2025 Feb 20;41(1):46
Cell biology and toxicology 2025 Feb 20;41(1):46
Optineurin-facilitated axonal mitochondria delivery promotes neuroprotection and axon regeneration.
Liu D, Webber HC, Bian F, Xu Y, Prakash M, Feng X, Yang M, Yang H, You IJ, Li L, Liu L, Liu P, Huang H, Chang CY, Liu L, Shah SH, La Torre A, Welsbie DS, Sun Y, Duan X, Goldberg JL, Braun M, Lansky Z, Hu Y
Nature communications 2025 Feb 20;16(1):1789
Nature communications 2025 Feb 20;16(1):1789
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Liu Y, Yu Y, Chen C, Wu X, Zheng Q, Zhang X, Ye L, Zhang C, Feng Z
International immunopharmacology 2025 Feb 20;148:114117
International immunopharmacology 2025 Feb 20;148:114117
Distinct Roles of Astrocytes and GABAergic Neurons in the Paraventricular Thalamic Nucleus in Modulating Diabetic Neuropathic Pain.
Chen J, Yang L, Shen J, Lu J, Mo X, Huang L, Chen L, Yu C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Feb 19;45(8)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Feb 19;45(8)
TREM2 deficiency aggravates neuroinflammatory response and cognitive impairment via disease-associated microglia in Parkinson's disease models.
Zhang P, Zhu B, Feng J, Liang X, Huang P, He C, Deng Y, Lu J, Wang L, Zhang Y
Neurochemistry international 2025 Dec;191:106068
Neurochemistry international 2025 Dec;191:106068
Reprogramming activated astrocytes into GABAergic neurons to treat trigeminal neuralgia.
Xia S, Chen K, Li X, Zou D, Wang M, Wang Y
Neurochemistry international 2025 Dec;191:106067
Neurochemistry international 2025 Dec;191:106067
Dietary cholesterol impairs cognition via gut microbiota-derived deoxycholic acid in obese mice.
Liu Y, Wang Z, Zhang Y, Zhao T, Zhang Q, Huang W, Lu B
Gut microbes 2025 Dec;17(1):2537753
Gut microbes 2025 Dec;17(1):2537753
Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension.
Shi Y, Zhang YX, Chen JY, Ma S, Xue WX, Li W, Li QX, Song B, Li YT, Ma HY, Xie ST, Li HZ, Chen DJ, Zhang QP, Ma HJ, Wang JJ, Yu L, Zhang XY, Zhu JN
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e08176
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e08176
Repetitive transcranial magnetic stimulation ameliorates myocardial injury in vascular dementia via renin-angiotensin system modulation.
Li J, Su J, Zhu B, Gao X
Neuroreport 2025 Dec 10;36(18):1072-1080
Neuroreport 2025 Dec 10;36(18):1072-1080
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Hao S, Luo J, Yuan S, Chen W, Zhang X, Zhao C, Xu H, Liu Z, Zhang D
Free radical biology & medicine 2025 Dec 1;240:1-14
Free radical biology & medicine 2025 Dec 1;240:1-14
Biliverdin alleviates cerebral ischemia-reperfusion injury by regulating the P4hb/MAPK/mTOR pathway to inhibit autophagy.
Jiang H, Bai W, Yang Y, Zhou G, Li J, Li X, Wan X, Shao J
Cellular signalling 2025 Aug;132:111815
Cellular signalling 2025 Aug;132:111815
Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity.
Dai B, Fan Z, Chen R, Weng X, Fang R
Neuromolecular medicine 2025 Aug 6;27(1):57
Neuromolecular medicine 2025 Aug 6;27(1):57
Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia.
Wang YC, Huang YY, E ED, Fu CX, Li JW, Mi YW, Zhong N, Yang FR, Zhang T, Xu LM, Zhang XQ
Progress in neuro-psychopharmacology & biological psychiatry 2025 Aug 30;141:111476
Progress in neuro-psychopharmacology & biological psychiatry 2025 Aug 30;141:111476
Remote Ischemic Conditioning Attenuates Apoptosis, the Inflammatory Response, and Reperfusion Injury in Ischemic-Stroke Model Rats via the ELA-Apelin-APJ System.
Zhou F, Wu Y, Chen X, Pan Z, Wang X, Gao S, Shi C, Ren J, Shi J
Journal of integrative neuroscience 2025 Aug 28;24(8):39897
Journal of integrative neuroscience 2025 Aug 28;24(8):39897
Effect of the DPP4 Inhibitor Sitagliptin on Ferroptosis in Epilepsy.
Hou B, Li L, Wang F, Guo J
Journal of integrative neuroscience 2025 Aug 28;24(8):39469
Journal of integrative neuroscience 2025 Aug 28;24(8):39469
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Xu L, Ma Y, Jiang G, Cao Z, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
International immunopharmacology 2025 Aug 28;161:115086
International immunopharmacology 2025 Aug 28;161:115086
In vitro axotomy models regulated by ROCK inhibitor for studying neuroregeneration and growth cone morphology.
Fang F, Xu D, Dou S, Zhan S, Fan Y, Zhuang Y, Xu W, Xu Z
Biomedical journal 2025 Aug 23;:100908
Biomedical journal 2025 Aug 23;:100908
An Elongator mouse model of ALS spotlights TDP-43 in the motor neuron nucleolus.
Snow M, Cameron B, Pond R, Trudell R, Snyder S, Torres-Hernandez L, Deschamps D, Tulimaiau D, Hawkinson K, Russell M, Horan D, Walters J, Fox JH, Arlian B, Chariot A, Nguyen L, George L
Communications biology 2025 Aug 21;8(1):1259
Communications biology 2025 Aug 21;8(1):1259
Charting the spatial transcriptome of the human cerebral cortex at single-cell resolution.
Wei S, Luo M, Wang P, Chen R, Jin X, Xu C, Li C, Lin X, Xu Z, Liu H, Cheng R, Yang W, Cai Y, Xue G, Huang P, Liu Z, Sun H, Xu J, Jiang Q
Nature communications 2025 Aug 19;16(1):7702
Nature communications 2025 Aug 19;16(1):7702
Gut microbiota's role in high-altitude cognitive impairment: the therapeutic potential of Clostridium sp. supplementation.
Zhou W, Zhou Y, Zhang S, Li B, Li Z, Bai Z, Sun D, Huangfu C, Wang N, Xia T, Huang C, Guan L, Yang X, Hu Y, Zhang P, Shen P, Wang R, Ni Z, Gao Y
Science China. Life sciences 2025 Apr;68(4):1132-1148
Science China. Life sciences 2025 Apr;68(4):1132-1148
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Wang J, Peng J, Gao L, He J, Lin L, Li JM, Xia Y
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson's Disease.
Xu HT, Xi XY, Zhou S, Xie YY, Cui ZS, Zhang BB, Xie ST, Li HZ, Zhang QP, Pan Y, Zhang XY, Zhu JN
Neuroscience bulletin 2025 Apr;41(4):551-568
Neuroscience bulletin 2025 Apr;41(4):551-568
Transcription factor AP-2 Beta, a potential target of repetitive Transspinal magnetic stimulation in spinal cord injury treatment, reduced inflammation and alleviated spinal cord injury.
Yang Y, Shao Y, Dai Q, Zhang Y, Sun Y, Wang K, Xu A
Experimental neurology 2025 Apr;386:115144
Experimental neurology 2025 Apr;386:115144
Intravenous tenecteplase bridging reperfusion ameliorates cerebral ischemia/reperfusion injury by improving microvascular circulation in rats.
Ning YX, Cai JR, Wang TT, Wang YH, Cui Y, Chen HS
Journal of thrombosis and haemostasis : JTH 2025 Apr;23(4):1352-1366
Journal of thrombosis and haemostasis : JTH 2025 Apr;23(4):1352-1366
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Li X, Jin S, Wang D, Wu Y, Tang X, Liu Y, Yao T, Han S, Sun L, Wang Y, Hou SX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability.
Wang K, Zhang Y, Shu R, Yuan L, Tu H, Wang S, Ni B, Zhang YF, Jiang C, Luo Y, Yin Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2417367
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2417367
Macrophage migration inhibitory factor in the mouse hippocampus promotes neuroinflammation and cognitive dysfunction following anesthesia and surgery.
Zeng L, Hu PC, Zhang Y, Han TT, Wang X, Zhao YL, Li SY, Luo AL
International immunopharmacology 2025 Apr 4;151:114351
International immunopharmacology 2025 Apr 4;151:114351
Citrus medica L. essential oil improves anxiety-like behaviors accompanied by fatigue through α7-nAChR receptor-mediated neuroprotection effects.
Yang Y, Song Y, Xu W, Ai Z, Zhu G, Yang M, Zheng Q, Xu H, Liu Y, Ping Y, Su D
Journal of ethnopharmacology 2025 Apr 25;346:119667
Journal of ethnopharmacology 2025 Apr 25;346:119667
Electroacupuncture Ameliorates Chronic Inflammatory Pain and Depression Comorbidity by Inhibiting Nrf2-Mediated Ferroptosis in Hippocampal Neurons.
Liu G, Liu D, Shi D, Wang Z, Fu W
Neurochemical research 2025 Apr 21;50(3):149
Neurochemical research 2025 Apr 21;50(3):149
Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.
Zhou L, Godse S, Sinha N, Ma D, Mirzahosseini G, Salman M, Pulliam P, Tan C, Singh UP, Ishrat T, Kochat H, Kumar S
ACS applied nano materials 2025 Apr 11;8(14):6857-6876
ACS applied nano materials 2025 Apr 11;8(14):6857-6876
Transient receptor potential vanilloid 4 blockage attenuates pyroptosis in hippocampus of mice following pilocarpine‑induced status epilepticus.
Liu L, Wang Y, Wang X, Zhang G, Sha S, Zhou R, Du Y, Wu C, Chen L
Acta neuropathologica communications 2025 Apr 10;13(1):73
Acta neuropathologica communications 2025 Apr 10;13(1):73
Effects of electroacupuncture per-conditioning at Huantiao on motor function recovery in acute cerebral ischemia mice.
Fu JL, Zhang JJ, Wu Y, Wang NH, Qi Q, Yang GH, Ren N, Huang D, Li Y, Zhao LJ, Cui X, Xiao X, Xie HY
Physiology & behavior 2025 Apr 1;292:114814
Physiology & behavior 2025 Apr 1;292:114814
Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis.
Tang X, Zheng N, Lin Q, You Y, Gong Z, Zhuang Y, Wu J, Wang Y, Huang H, Ke J, Chen F
Neural regeneration research 2025 Apr 1;20(4):1103-1123
Neural regeneration research 2025 Apr 1;20(4):1103-1123
Shenfu Injection Mediated NLRP3/Caspase 1 Through (R)-Norcoclaurinee Alleviates Sepsis-Induced Cognitive Dysfunction.
Liu X, Ding H, Chen M, Li X, Xiao Y, Han Y, Zeng H
Journal of inflammation research 2024;17:7295-7310
Journal of inflammation research 2024;17:7295-7310
APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases.
Perez-Corredor P, Vanderleest TE, Vacano GN, Sanchez JS, Villalba-Moreno ND, Marino C, Krasemann S, Mendivil-Perez MA, Aguillón D, Jiménez-Del-Río M, Baena A, Sepulveda-Falla D, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Mazzarino RC
Frontiers in molecular neuroscience 2024;17:1373568
Frontiers in molecular neuroscience 2024;17:1373568
Microglial adenosine A(2A) receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.
Cao Y, Wu Z, Zhang M, Ji R, Zhang H, Song L
Frontiers in pharmacology 2024;15:1467305
Frontiers in pharmacology 2024;15:1467305
Comparative analysis of two independent Myh6-Cre transgenic mouse lines.
Davenport A, Kessinger CW, Pfeiffer RD, Shah N, Xu R, Abel ED, Tucker NR, Lin Z
Journal of molecular and cellular cardiology plus 2024 Sep;9
Journal of molecular and cellular cardiology plus 2024 Sep;9
E3 ubiquitin ligase MARCH1 reduces inflammation and pyroptosis in cerebral ischemia-reperfusion injury via PCSK9 downregulation.
Guo H, Li W, Yang Z, Xing X
Mammalian genome : official journal of the International Mammalian Genome Society 2024 Sep;35(3):346-361
Mammalian genome : official journal of the International Mammalian Genome Society 2024 Sep;35(3):346-361
Elucidating the molecular mechanisms behind the therapeutic impact of median nerve stimulation on cognitive dysfunction post-traumatic brain injury.
Zhong YJ, Liu LL, Zhao Y, Feng Z, Liu Y
Experimental gerontology 2024 Sep;194:112500
Experimental gerontology 2024 Sep;194:112500
Therapeutic effect of nicotinamide mononucleotide on Alzheimer's disease through activating autophagy and anti-oxidative stress.
Ma RY, Li L, Yang H, Zou B, Ma RX, Zhang Y, Wu MM, Chen P, Yao Y, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117199
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117199
Withaferin A protects against epilepsy by promoting LCN2-mediated astrocyte polarization to stopping neuronal ferroptosis.
Zhou Z, Zhang P, Ya D, Liu J, Xu Y, Zhang Y, Tang W, Zhou D, Liao R, Liu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155892
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155892
Oxytocin Protects Nigrostriatal Dopamine Signal via Activating GABAergic Circuit in the MPTP-Induced Parkinson's Disease Model.
Wang Y, Xu H, Chen S, Chen J, Zheng Q, Ma Y, Zhao X, Shi Y, Xiao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2310244
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2310244
AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice.
Chauhan M, Daugherty AL, Khadir FE, Duzenli OF, Hoffman A, Tinklenberg JA, Kang PB, Aslanidi G, Pacak CA
Journal of translational medicine 2024 Sep 5;22(1):824
Journal of translational medicine 2024 Sep 5;22(1):824
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
Yang S, Du Y, Li Y, Tang Q, Zhang Y, Zhao X
Journal of neuroinflammation 2024 Sep 3;21(1):218
Journal of neuroinflammation 2024 Sep 3;21(1):218
SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures.
Zhu J, Liu X, Liu Z, Deng Y, Xu J, Liu K, Zhang R, Meng X, Fei P, Yu T, Zhu D
Nature communications 2024 Sep 27;15(1):8303
Nature communications 2024 Sep 27;15(1):8303
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice.
Zhong P, Li L, Feng X, Teng C, Cai W, Zheng W, Wei J, Li X, He Y, Chen B, An X, Cai X
International immunopharmacology 2024 Sep 10;138:112579
International immunopharmacology 2024 Sep 10;138:112579
Ferroptosis contributes to diabetes-induced visual pathway neuronal damage via iron accumulation and GPX4 inactivation.
Wang B, Jin Y, Ouyang X, Zhu R, Wang X, Li S, Jiang F
Metabolic brain disease 2024 Oct;39(7):1459-1468
Metabolic brain disease 2024 Oct;39(7):1459-1468
Curcumin attenuated neuroinflammation via the TLR4/MyD88/NF-κB signaling way in the juvenile rat hippocampus following kainic acid-induced epileptic seizures.
Fang Q, Cai Y, Yang Y, Zhang J, Ke J, Luo J, Zheng Y, Zhang Z, Alidu AJ, Wang Q, Huang X
Metabolic brain disease 2024 Oct;39(7):1387-1403
Metabolic brain disease 2024 Oct;39(7):1387-1403
The Activation of PKM2 Induces Pyroptosis in Hippocampal Neurons via the NLRP3/Caspase-1/GSDMD Pathway in Neonatal Rats With Hypoxic-Ischemic Brain Injury.
Sha S, Jin N, Zhou R, Ruan Y, Ouyang Y
Brain and behavior 2024 Oct;14(10):e70108
Brain and behavior 2024 Oct;14(10):e70108
Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study.
Jiang F, Cai H, Li H, Yin W, Ouyang S, Hu J, Tu E, Fu K, Yin J, Zhao Z, Yang J, Zeng Q, Yang H
Annals of clinical and translational neurology 2024 Oct;11(10):2769-2784
Annals of clinical and translational neurology 2024 Oct;11(10):2769-2784
Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice.
Dang R, Liu A, Zhou Y, Li X, Wu M, Cao K, Meng Y, Zhang H, Gan G, Xie W, Jia Z
Nature communications 2024 Oct 5;15(1):8639
Nature communications 2024 Oct 5;15(1):8639
Avicularin Treatment Ameliorates Ischemic Stroke Damage by Regulating Microglia Polarization and its Exosomes via the NLRP3 Pathway.
Shi Y, Yang Y, Liu J, Zheng J
Journal of integrative neuroscience 2024 Oct 30;23(11):196
Journal of integrative neuroscience 2024 Oct 30;23(11):196
Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.
Li T, Zhang L, Wang P, Yu J, Zhong J, Tang Q, Zhu T, Chen K, Li F, Hong P, Wei J, Sun X, Ji G, Song B, Zhu J
Cell reports 2024 Oct 22;43(10):114854
Cell reports 2024 Oct 22;43(10):114854
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Li M, Yang F, Zhang X, Yang H, He X, Mao Z, Mao L
Neuroreport 2024 Oct 2;35(14):947-960
Neuroreport 2024 Oct 2;35(14):947-960
Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage.
Li Y, Zhu X, Xiong W, Zhao Q, Zhou Y, Guo Y, Liu B, Li M, Chen Q, Jiang X, Qi Y, Ye Q, Deng G
Journal of nanobiotechnology 2024 Oct 18;22(1):641
Journal of nanobiotechnology 2024 Oct 18;22(1):641
Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia.
Wang B, Le DS, Liu L, Zhang XX, Yang F, Lai GR, Zhang C, Zhao ML, Shen YP, Liao PS, Liu T, Liang YP
Cell reports. Medicine 2024 Oct 15;5(10):101782
Cell reports. Medicine 2024 Oct 15;5(10):101782
The effect of repetitive magnetic stimulation on neuronal apoptosis and PI3K/Akt protein expression in rats with incomplete spinal cord injury.
Su J, Zhou F, Hu M, Xu Q, Huang Y, Chen S, Zhou H, Chen H
Journal of neurophysiology 2024 Oct 1;132(4):1211-1222
Journal of neurophysiology 2024 Oct 1;132(4):1211-1222
TRIM21-mediated ubiquitination of PLIN2 regulates neuronal lipid droplet accumulation after acute spinal cord injury.
Zhang Z, Li Z, Peng Y, Li Z, Xv N, Jin L, Cao Y, Jiang C, Chen Z
Experimental neurology 2024 Nov;381:114916
Experimental neurology 2024 Nov;381:114916
Neuroprotective effects of mesenchymal stromal cells in mouse models of Alzheimer's Disease: The Mediating role of gut microbes and their metabolites via the Microbiome-Gut-Brain axis.
Xing C, Zhang X, Wang D, Chen H, Gao X, Sun C, Guo W, Roshan S, Li Y, Hang Z, Cai S, Lei T, Bi W, Hou L, Li L, Wu Y, Li L, Zeng Z, Du H
Brain, behavior, and immunity 2024 Nov;122:510-526
Brain, behavior, and immunity 2024 Nov;122:510-526
RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway.
Wang Q, Li S, Wu W, Zhou W, Yan K, Liu Z, Yan L, Zheng B, Zhang F, Jiang X, Ye Y, Wang H
Cell communication and signaling : CCS 2024 Nov 7;22(1):535
Cell communication and signaling : CCS 2024 Nov 7;22(1):535
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
Zhang X, Feng Y, Zhong Y, Ding R, Guo Y, Jiang F, Xing Y, Shi H, Bao H, Si Y
ACS chemical neuroscience 2024 Nov 20;15(22):4185-4201
ACS chemical neuroscience 2024 Nov 20;15(22):4185-4201
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Lao D, Gong Z, Li T, Mo X, Huang W
Neurochemical research 2024 Nov 19;50(1):21
Neurochemical research 2024 Nov 19;50(1):21
Abnormal hippocampal neurogenesis and impaired social recognition memory in two neurodevelopmental models of schizophrenia.
Dong Y, Fu C, Zhang T, Dong F, Zhu X, Jiang Y, Hu L, Pan L, Li J, Zhang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70138
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70138
Neuronostatin regulates neuronal function and energetic metabolism in Alzheimer's disease in a GPR107-dependent manner.
Yang S, Tang Q, Zhang Y, Du Y, Zhao X, Mei F, Li Y
Neuropharmacology 2024 Nov 1;258:110090
Neuropharmacology 2024 Nov 1;258:110090
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
Duan L, Hao Z, Ji R, Li X, Wang H, Su Y, Guan F, Ma S
International journal of biological macromolecules 2024 May;268(Pt 1):131739
International journal of biological macromolecules 2024 May;268(Pt 1):131739
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9
Cell metabolism 2024 May 7;36(5):1059-1075.e9
Chronic stress induces Alzheimer's disease-like pathologies through DNA damage-Chk1-CIP2A signaling.
Wang Z, Zhang L, Yang J, Zeng Y, Su C, Yao M, Zhang H, Hu W, Liu Y, Lai Y, Wang X, Zeng J, Liu R
Aging 2024 May 30;16(10):9168-9187
Aging 2024 May 30;16(10):9168-9187
Pin1 Downregulation Is Involved in Excess Retinoic Acid-Induced Failure of Neural Tube Closure.
Chen Y, Pang J, Ye L, Zhang Z, Kang J, Qiu Z, Lin N, Liu H
International journal of molecular sciences 2024 May 21;25(11)
International journal of molecular sciences 2024 May 21;25(11)
Dl-3-n-Butylphthalide Alleviates Secondary Brain Damage and Improves Working Memory After Stroke in Cynomolgus Monkeys.
Jiang Z, Wei J, Liang J, Huang W, Ouyang F, Chen C, Li P, Cao S, Cai Y, Li J, Huang B, Zeng J, Chen Y
Stroke 2024 Mar;55(3):725-734
Stroke 2024 Mar;55(3):725-734
Role of an interdependent Wnt, GSK3-β/β-catenin and HB-EGF/EGFR mechanism in arsenic-induced hippocampal neurotoxicity in adult mice.
Garg A, Bandyopadhyay S
Chemosphere 2024 Mar;352:141375
Chemosphere 2024 Mar;352:141375
CD8(+) T cell infiltration and proliferation in the brainstem during experimental cerebral malaria.
Wang J, Zhu Q, Shen Y, Liang J, Wang Y, Huang Y, Tong G, Wang X, Zhang N, Yu K, Li Y, Zhao Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14431
CNS neuroscience & therapeutics 2024 Mar;30(3):e14431
Enhanced axon outgrowth of spinal motor neurons in co-culturing with dorsal root ganglions antagonizes the growth inhibitory environment.
Xu ZX, Xu D, Fang F, Fan YJ, Wu B, Chen YF, Huang HE, Huang XH, Zhuang YH, Xu WH
Regenerative therapy 2024 Mar;25:68-76
Regenerative therapy 2024 Mar;25:68-76
Novel perfluorocarbon-based oxygenation therapy alleviates Post-SAH hypoxic brain injury by inhibiting HIF-1α.
Peng Z, Ye QS, Li XJ, Zheng DY, Zhou Y, Hang CH, Wu JH, Li W, Zhuang Z
Free radical biology & medicine 2024 Mar;214:173-183
Free radical biology & medicine 2024 Mar;214:173-183
Physical and social environmental enrichment alleviate ferroptosis and inflammation with inhibition of TLR4/MyD88/p38MAPK pathway in chronic cerebral hypoperfusion rats.
Fan B, Zhang Y, Luo Q, Hao C, Liao W
Brain research bulletin 2024 Mar;208:110897
Brain research bulletin 2024 Mar;208:110897
Oxidative stress and mitochondrial dysfunction in brain of vinclozolin exposed animals.
Interdonato L, Marino Y, D'Amico R, Impellizzeri D, Cordaro M, Siracusa R, Gugliandolo E, Franco GA, Fusco R, Cuzzocrea S, Di Paola R
Neurochemistry international 2024 Mar;174:105681
Neurochemistry international 2024 Mar;174:105681
Overexpression of forebrain PTP1B leads to synaptic and cognitive impairments in obesity.
Ge X, Hu M, Zhou M, Fang X, Chen X, Geng D, Wang L, Yang X, An H, Zhang M, Lin D, Zheng M, Cui X, Wang Q, Wu Y, Zheng K, Huang XF, Yu Y
Brain, behavior, and immunity 2024 Mar;117:456-470
Brain, behavior, and immunity 2024 Mar;117:456-470
Mechanism of Dendrobium Nobile Polysaccharide Inhibition of Ferroptosis in Rats with Spinal Cord Injury.
Huang J, Luo J, Huang Y, Wang L, Zhu H, Li Z, Chen J
Journal of integrative neuroscience 2024 Mar 21;23(3):65
Journal of integrative neuroscience 2024 Mar 21;23(3):65
Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons.
Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S
eLife 2024 Mar 21;12
eLife 2024 Mar 21;12
Prenatal diesel exhaust exposure alters hippocampal synaptic plasticity in offspring.
Yu S, Zhang Z, Qin Z, Liu M, Zhao X, Cheng Y, Xue P, Wang X, Chen L, Wu Q, Ju L, Tang J
Aging 2024 Mar 1;16(5):4348-4362
Aging 2024 Mar 1;16(5):4348-4362
PTPRO inhibition ameliorates spinal cord injury through shifting microglial M1/M2 polarization via the NF-κB/STAT6 signaling pathway.
Zhang H, Xiang L, Yuan H, Yu H
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167141
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167141
Effects of a novel regimen of repetitive transcranial magnetic stimulation (rTMS) on neural remodeling and motor function in adult male mice with ischemic stroke.
Peipei W, Yu D, Xiaoyan L, Yunxia L, Liuming L, Tongbin C, Shaoping L
Journal of neuroscience research 2024 Jun;102(6):e25358
Journal of neuroscience research 2024 Jun;102(6):e25358
Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition.
Huang LY, Zhang YD, Liu YN, Liang ZY, Chen J, Wang B, Yin QL, Wang PP, Wang W, Qi SH
ACS chemical neuroscience 2024 Jun 5;15(11):2223-2232
ACS chemical neuroscience 2024 Jun 5;15(11):2223-2232
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Porter CM, Tabler S, Choi S, Truttmann MC
Scientific reports 2024 Jun 3;14(1):12688
Scientific reports 2024 Jun 3;14(1):12688
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy.
Zhao Q, Chen L, Zhang X, Yang H, Li Y, Li P
Chinese medicine 2024 Jun 15;19(1):86
Chinese medicine 2024 Jun 15;19(1):86
Development of adenoviral vectors that transduce Purkinje cells and other cerebellar cell-types in the cerebellum of a humanized mouse model.
Kul E, Okoroafor U, Dougherty A, Palkovic L, Li H, Valiño-Ramos P, Aberman L, Young SM Jr
Molecular therapy. Methods & clinical development 2024 Jun 13;32(2):101243
Molecular therapy. Methods & clinical development 2024 Jun 13;32(2):101243
Intestinal microbiota via NLRP3 inflammasome dependent neuronal pyroptosis mediates anxiety-like behaviour in mice exposed to 3.5 GHz radiofrequency radiation.
Zhou GQ, Wang X, Gao P, Qin TZ, Guo L, Zhang ZW, Huang ZF, Lin JJ, Jing YT, Wang HN, Wang CP, Ding GR
The Science of the total environment 2024 Jun 1;927:172391
The Science of the total environment 2024 Jun 1;927:172391
Ablated Sonic Hedgehog Signaling in the Dentate Gyrus of the Dorsal and Ventral Hippocampus Impairs Hippocampal-Dependent Memory Tasks and Emotion in a Rat Model of Depression.
Luo Y, Wang Y, Qiu F, Hou G, Liu J, Yang H, Wu M, Dong X, Guo D, Zhong Z, Zhang X, Ge J, Meng P
Molecular neurobiology 2024 Jul;61(7):4352-4368
Molecular neurobiology 2024 Jul;61(7):4352-4368
Augmentation of functional recovery via ROCK/PI3K/AKT pathway by Fasudil Hydrochloride in a rat sciatic nerve transection model.
Wang H, Fang F, Jing X, Xu D, Ren Z, Dou S, Xie Y, Zhuang Y
Journal of orthopaedic translation 2024 Jul;47:74-86
Journal of orthopaedic translation 2024 Jul;47:74-86
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice.
Huang D, Fan Y, Zhang J, Wang Q, Ding M, Hou R, Yu K, Xiao X, Wu Y, Wu J
Experimental neurology 2024 Jul;377:114801
Experimental neurology 2024 Jul;377:114801
The suppressive effect of the specific KCC2 modulator CLP290 on seizure in mice.
Cai J, Wu Z, Wang G, Zhao X, Wang X, Wang BH, Yu J, Liu X, Wang Y
Epilepsy research 2024 Jul;203:107365
Epilepsy research 2024 Jul;203:107365
Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury.
Chen J, Zhang C, Yang Z, Wu W, Zou W, Xin Z, Zheng S, Liu R, Yang L, Peng H
Parasites & vectors 2024 Jul 2;17(1):284
Parasites & vectors 2024 Jul 2;17(1):284
CDK5-USP30 signaling pathway regulates MAVS-mediated inflammation via suppressing mitophagy in MPTP/MPP(+) PD model.
Ren Y, Wu X, Bai T, Yang N, Yuan Y, Xu L, Wen Y, Wen Y, Wang Z, Zhou L, Zou F, Li W
Ecotoxicology and environmental safety 2024 Jul 1;279:116446
Ecotoxicology and environmental safety 2024 Jul 1;279:116446
Melatonin Exerts an Anti-Panoptoic Role in Spinal Cord Ischemia-Reperfusion Injured Rats.
Xie L, Wu H, Shi W, Zhang J, Huang X, Yu T
Advanced biology 2024 Jan;8(1):e2300424
Advanced biology 2024 Jan;8(1):e2300424
Activation of G protein-coupled receptor 39 alleviates neuropathic pain and chronic inflammation.
Cheng F, Yan F, Yang A, Liu J, Ma J
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23545
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23545
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Huo J, Dong W, Xu J, Ma L, You C
Experimental neurology 2024 Jan;371:114577
Experimental neurology 2024 Jan;371:114577
Selective homing of brain-derived reconstituted lipid nanoparticles to cerebral ischemic area enables improved ischemic stroke treatment.
Han D, Wang M, Dong N, Zhang J, Li D, Ma X, Ma Y, Wang S, Zhu Y, Wang C
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:957-968
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:957-968
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Acacetin inhibits activation of microglia to improve neuroinflammation after subarachnoid hemorrhage through the PERK signaling pathway mediated autophagy.
Liu Y, Tang J, Hou Y, Li L, Li W, Yu L, Wang X, Sui C
Human & experimental toxicology 2024 Jan-Dec;43:9603271241251447
Human & experimental toxicology 2024 Jan-Dec;43:9603271241251447
A circRNA ceRNA network involved in cognitive dysfunction after chronic cerebral hypoperfusion.
Jiang WR, Zhou YM, Wu W, Yang LJ, Wu Y, Zhang XY, Yao ZH
Aging 2024 Jan 16;16(2):1161-1181
Aging 2024 Jan 16;16(2):1161-1181
Demethylase FTO-Mediated m6A Modification of lncRNA MEG3 Activates Neuronal Pyroptosis via NLRP3 Signaling in Cerebral Ischemic Stroke.
Yan H, Huang W, Rao J, Yan D, Yuan J
Molecular neurobiology 2024 Feb;61(2):1023-1043
Molecular neurobiology 2024 Feb;61(2):1023-1043
Increased Expression of K(Na)1.2 Channel by MAPK Pathway Regulates Neuronal Activity Following Traumatic Brain Injury.
Liu R, Sun L, Shi X, Li C, Guo X, Wang Y, Wang X, Zhang K, Wang Y, Wang Q, Wu J
Neurochemical research 2024 Feb;49(2):427-440
Neurochemical research 2024 Feb;49(2):427-440
Tangeretin Attenuates Cerebral Ischemia-Reperfusion-Induced Neuronal Pyroptosis by Inhibiting AIM2 Inflammasome Activation via Regulating NRF2.
You G, Zheng L, Zhang Y, Zhang Y, Wang Y, Guo W, Liu H, Tatiana P, Vladimir K, Zan J
Inflammation 2024 Feb;47(1):145-158
Inflammation 2024 Feb;47(1):145-158
Loss of Slc39a12 in hippocampal neurons is responsible for anxiety-like behavior caused by temporomandibular joint osteoarthritis.
Shen Z, Fan C, Ding C, Xu M, Wu X, Wang Y, Xing T
Heliyon 2024 Feb 29;10(4):e26271
Heliyon 2024 Feb 29;10(4):e26271
TsMS combined with EA promotes functional recovery and axonal regeneration via mediating the miR-539-5p/Sema3A/PlexinA1 signalling axis in sciatic nerve-injured rats.
Wang X, Hu S, Ouyang S, Pan X, Fu Y, Chen X, Wu S
Neuroscience letters 2024 Feb 28;824:137691
Neuroscience letters 2024 Feb 28;824:137691
The Primary Cilium and its Hedgehog Signaling in Nociceptors Contribute to Inflammatory and Neuropathic Pain.
Fitzsimons LA, Staurengo-Ferrari L, Bogen O, Araldi D, Bonet IJM, Jordan EE, Levine JD, Tucker KL
Research square 2024 Feb 26;
Research square 2024 Feb 26;
The role of ApoE in fatty acid transport from neurons to astrocytes under ischemia/hypoxia conditions.
Chen H, Zhao S, Jian Q, Yan Y, Wang S, Zhang X, Ji Y
Molecular biology reports 2024 Feb 23;51(1):320
Molecular biology reports 2024 Feb 23;51(1):320
The compensatory increase of Gli-similar 3 inhibited neuronal apoptosis through regulating Mps one binder kinase activator 1b (MOB1b): a possible strategy for the functional recovery after spinal cord injury.
Yang HB, Li Y, Li XH, Yan QM, Han XZ, Cao J, Sang HP, Li JL
Experimental animals 2024 Feb 14;73(1):61-72
Experimental animals 2024 Feb 14;73(1):61-72
Eriocalyxin B alleviated ischemic cerebral injury by limiting microglia-mediated excessive neuroinflammation in mice.
Chen Y, Zhang C, Zhao L, Chen R, Zhang P, Li J, Zhang X, Zhang X
Experimental animals 2024 Feb 14;73(1):124-135
Experimental animals 2024 Feb 14;73(1):124-135
Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.
Lan Y, Zhang X, Liu S, Guo C, Jin Y, Li H, Wang L, Zhao J, Hao Y, Li Z, Liu Z, Ginhoux F, Xie Q, Xu H, Jia JM, He D
Immunity 2024 Feb 13;57(2):349-363.e9
Immunity 2024 Feb 13;57(2):349-363.e9
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing.
Yu W, Li Y, Zhong F, Deng Z, Wu J, Yu W, Lü Y
Cellular and molecular neurobiology 2024 Feb 12;44(1):20
Cellular and molecular neurobiology 2024 Feb 12;44(1):20
Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.
Gao TX, Liang Y, Li J, Zhao D, Dong BJ, Xu C, Zhao WD, Li X, Zhao CS
Experimental neurology 2024 Dec;382:114983
Experimental neurology 2024 Dec;382:114983
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Li X, Li J, Ji J, Li S, Yao X, Fan H, Yao R
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Sun X, Xu S, Wang J, Li X, Sun H, Zhao W
Neuroreport 2024 Dec 4;35(17):1107-1116
Neuroreport 2024 Dec 4;35(17):1107-1116
Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss.
Wu C, Deng Q, Zhu L, Liu TC, Duan R, Yang L
Molecular neurobiology 2024 Aug;61(8):5787-5801
Molecular neurobiology 2024 Aug;61(8):5787-5801
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Dingyi L, Libin H, Jifeng P, Ding Z, Yulong L, Zhangyi W, Yunong Y, Qinghua W, Feng L
Experimental brain research 2024 Aug;242(8):1917-1932
Experimental brain research 2024 Aug;242(8):1917-1932
Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.
Tang X, Huang Y, Fu W, Wang P, Feng L, Yang J, Zhu H, Huang X, Ming Q, Li P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117046
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117046
Tetramethylpyrazine alleviates ferroptosis and promotes functional recovery in spinal cord injury by regulating GPX4/ACSL4.
Liu G, Deng B, Huo L, Fan X, Bai H, Zhao Y, Xu L, Gao F, Mu X
European journal of pharmacology 2024 Aug 15;977:176710
European journal of pharmacology 2024 Aug 15;977:176710
Peimine promotes microglial polarization to the M2 phenotype to attenuate drug-resistant epilepsy through suppressing the TLR4/NF-κB/HIF-1α signaling pathway in a rat model and in BV-2 microglia.
Liu C, Sun J, Shen X, Li S, Luo S, Chen N, Zhang Y
Heliyon 2024 Aug 15;10(15):e34987
Heliyon 2024 Aug 15;10(15):e34987
Selenoprotein H mediates low selenium-related cognitive decline through impaired oligodendrocyte myelination with disrupted hippocampal lipid metabolism in female mice.
Lv Q, Yang A, Han Z, Yu R, Zhu J, Shi Z, Yang C, Dai S, Hao M, Chen Y, Zhou JC
Food & function 2024 Aug 12;15(16):8544-8561
Food & function 2024 Aug 12;15(16):8544-8561
Inhibition of neuronal pentraxin 2 relieved epileptic seizure via reducing GluA1 phosphorylation.
Xing M, Yang X, Jin S, Xu X
Cell biochemistry and function 2024 Apr;42(3):e4003
Cell biochemistry and function 2024 Apr;42(3):e4003
SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy.
Yang J, Yu Z, Jiang Y, Zhang Z, Tian Y, Cai J, Wei M, Lyu Y, Yang D, Shen S, Xing GG, Li M
CNS neuroscience & therapeutics 2024 Apr;30(4):e14703
CNS neuroscience & therapeutics 2024 Apr;30(4):e14703
Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a.
Yang C, Kang F, Huang X, Wu W, Hou G, Zheng K, Han M, Kan B, Zhang Z, Li J
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167129
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167129
Benefits of Puerarin on Metabolic Syndrome and Its Associated Cardiovascular Diseases in Rats Fed a High-Fat/High-Sucrose Diet.
Mu Y, Yang Y, Jiang S, Liu C, Han Y, Jiang J, Wang Y
Nutrients 2024 Apr 25;16(9)
Nutrients 2024 Apr 25;16(9)
GSDMD/Drp1 signaling pathway mediates hippocampal synaptic damage and neural oscillation abnormalities in a mouse model of sepsis-associated encephalopathy.
Fu Q, Zhang YB, Shi CX, Jiang M, Lu K, Fu ZH, Ruan JP, Wu J, Gu XP
Journal of neuroinflammation 2024 Apr 16;21(1):96
Journal of neuroinflammation 2024 Apr 16;21(1):96
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peng Z, Ding YN, Yang ZM, Li XJ, Zhuang Z, Lu Y, Tang QS, Hang CH, Li W
Acta biomaterialia 2024 Apr 15;179:325-339
Acta biomaterialia 2024 Apr 15;179:325-339
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Meng P, Zhang X, Li D, Yang H, Lin X, Zhao H, Li P, Wang Y, Wang X, Ge J
Neural plasticity 2023;2023:1455634
Neural plasticity 2023;2023:1455634
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.
Fan Y, Yang Y, Lin K, Zhou X, Li Y, Lin Q
Open medicine (Warsaw, Poland) 2023;18(1):20230800
Open medicine (Warsaw, Poland) 2023;18(1):20230800
Lateral septal nucleus, dorsal part, and dentate gyrus are necessary for spatial and object recognition memory, respectively, in mice.
Jiang YK, Dong FY, Dong YB, Zhu XY, Pan LH, Hu LB, Xu L, Xu XF, Xu LM, Zhang XQ
Frontiers in behavioral neuroscience 2023;17:1139737
Frontiers in behavioral neuroscience 2023;17:1139737
Chaihu-Longgu-Muli decoction improves sleep disorders by restoring orexin-A function in CKD mice.
Cao XL, Peng XM, Li GB, Ding WS, Wang KZ, Wang XL, Xiong YY, Xiong WJ, Li F, Song M
Frontiers in endocrinology 2023;14:1206353
Frontiers in endocrinology 2023;14:1206353
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Xu Y, Chen B, Yi J, Tian F, Liu Y, Ouyang Y, Yuan C, Liu B
Frontiers in pharmacology 2023;14:1137609
Frontiers in pharmacology 2023;14:1137609
2-Deoxyglucose alleviates migraine-related behaviors by modulating microglial inflammatory factors in experimental model of migraine.
Qiu T, Zhou Y, Hu L, Shan Z, Zhang Y, Fang Y, Huang W, Zhang L, Fan S, Xiao Z
Frontiers in neurology 2023;14:1115318
Frontiers in neurology 2023;14:1115318
Adipose transplantation improves olfactory function and neurogenesis via PKCα-involved lipid metabolism in Seipin Knockout mice.
Yang J, Yang N, Zhao H, Qiao Y, Li Y, Wang C, Lim KL, Zhang C, Yang W, Lu L
Stem cell research & therapy 2023 Sep 7;14(1):239
Stem cell research & therapy 2023 Sep 7;14(1):239
Purified Serum IgG from a Patient with Anti-IgLON5 Antibody Cause Long-Term Movement Disorders with Impaired Dopaminergic Pathways in Mice.
Gao Y, Li H, Luo H, Ni Y, Feng Y, He L, Zhou Q, Hu J, Chen S
Biomedicines 2023 Sep 7;11(9)
Biomedicines 2023 Sep 7;11(9)
Telaprevir Improves Memory and Cognition in Mice Suffering Ischemic Stroke via Targeting MALT1-Mediated Calcium Overload and Necroptosis.
Zhang YY, Peng JJ, Chen D, Liu HQ, Yao BF, Peng J, Luo XJ
ACS chemical neuroscience 2023 Sep 6;14(17):3113-3124
ACS chemical neuroscience 2023 Sep 6;14(17):3113-3124
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Porter CM, Truttmann MC
bioRxiv : the preprint server for biology 2023 Sep 22;
bioRxiv : the preprint server for biology 2023 Sep 22;
Protocol for fine casting, imaging, and analysis of murine vascular networks with VALID.
Zhu J, Liu X, Xu J, Liu Z, Deng Y, Dai J, Yu T, Zhu D
STAR protocols 2023 Sep 15;4(3):102441
STAR protocols 2023 Sep 15;4(3):102441
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Lycium barbarum glycopeptide alleviates neuroinflammation in spinal cord injury via modulating docosahexaenoic acid to inhibiting MAPKs/NF-kB and pyroptosis pathways.
Jiang Z, Zeng Z, He H, Li M, Lan Y, Hui J, Bie P, Chen Y, Liu H, Fan H, Xia H
Journal of translational medicine 2023 Oct 31;21(1):770
Journal of translational medicine 2023 Oct 31;21(1):770
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Li H, Zhang C, Zhou Y, Deng Y, Zheng X, Xue X
Aging 2023 Oct 26;15(20):11639-11653
Aging 2023 Oct 26;15(20):11639-11653
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
Luo Q, Zheng J, Fan B, Liu J, Liao W, Zhang X
Brain research bulletin 2023 Oct 15;203:110778
Brain research bulletin 2023 Oct 15;203:110778
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Gao X, You Z, Huang C, Liu Z, Tan Z, Li J, Liu Y, Liu X, Wei F, Fan Z, Qi S, Sun J
Molecular neurobiology 2023 Nov;60(11):6676-6688
Molecular neurobiology 2023 Nov;60(11):6676-6688
The role of EndophilinA1 in chronic unpredicted mild stress-induced depression model mice.
Liu M, Ling Y, Zhang Y, Liu L, Qiu Y, Liu Y, Yin Y
International immunopharmacology 2023 Nov;124(Pt B):111023
International immunopharmacology 2023 Nov;124(Pt B):111023
Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation.
Iacono D, Murphy EK, Stimpson CD, Perl DP, Day RM
Scientific reports 2023 Nov 30;13(1):21142
Scientific reports 2023 Nov 30;13(1):21142
Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.
Zhu Q, Han Y, He Y, Fu Y, Yang H, Chen Y, Shi Y
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):311
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):311
The neuroprotective effect of dl-3-n-butylphthalide on the brain with experimental intracerebral hemorrhage.
Fang M, Hou H, Feng B, Zhang T, Zhu X, Liu Z
European journal of pharmacology 2023 Nov 15;959:176105
European journal of pharmacology 2023 Nov 15;959:176105
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Scientific reports 2023 Nov 14;13(1):19864
Scientific reports 2023 Nov 14;13(1):19864
Proinflammatory activation of microglia in the cerebellum hyperexcites Purkinje cells to trigger ataxia.
Xie ST, Fan WC, Zhao XS, Ma XY, Li ZL, Zhao YR, Yang F, Shi Y, Rong H, Cui ZS, Chen JY, Li HZ, Yan C, Zhang Q, Wang JJ, Zhang XY, Gu XP, Ma ZL, Zhu JN
Pharmacological research 2023 May;191:106773
Pharmacological research 2023 May;191:106773
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Liu Y, Mi Y, Wang Y, Meng Q, Xu L, Liu Y, Zhou D, Wang Y, Liang D, Li W, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Involvement of Mrgprd-expressing nociceptors-recruited spinal mechanisms in nerve injury-induced mechanical allodynia.
Wang L, Su X, Yan J, Wu Q, Xu X, Wang X, Liu X, Song X, Zhang Z, Hu W, Liu X, Zhang Y
iScience 2023 May 19;26(5):106764
iScience 2023 May 19;26(5):106764
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Li Y, Zhang L, Mao M, He L, Wang T, Pan Y, Zhao X, Li Z, Mu X, Qian Y, Qiu J
iScience 2023 May 19;26(5):106744
iScience 2023 May 19;26(5):106744
Downregulation of High mobility group box 2 relieves spinal cord injury by inhibiting microglia-mediated neuroinflammation.
Yang P, He J, Wang C, Yang C, Jian F
Experimental animals 2023 May 17;72(2):199-208
Experimental animals 2023 May 17;72(2):199-208
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
He X, Guo X, Deng B, Kang J, Liu W, Zhang G, Wang Y, Yang Y, Kang X
Experimental neurology 2023 Mar;361:114301
Experimental neurology 2023 Mar;361:114301
Activation of metabotropic glutamate receptor 1 regulates hippocampal CA1 region excitability in rats with status epilepticus by suppressing the HCN1 channel.
Luo XD, Xiang T, Li SJ, Ma MG, Chen ML, Wu Y
Neural regeneration research 2023 Mar;18(3):594-602
Neural regeneration research 2023 Mar;18(3):594-602
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Lun J, Li Y, Gao X, Gong Z, Chen X, Zou J, Zhou C, Huang Y, Zhou B, Huang P, Cao H
Journal of neuroinflammation 2023 Mar 30;20(1):87
Journal of neuroinflammation 2023 Mar 30;20(1):87
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Ouyang S, Wang X, Chen Y, Deng L, Yang X, Hu S, Wu S
Neuroscience letters 2023 Mar 16;799:137104
Neuroscience letters 2023 Mar 16;799:137104
Activation of the High-Affinity Choline Transporter 1 in the Spinal Cord Relieves Stress-Induced Hyperalgesia.
Lin M, Hu G, Wang Z, Yu B, Tan W
Digestive diseases and sciences 2023 Jun;68(6):2414-2426
Digestive diseases and sciences 2023 Jun;68(6):2414-2426
Hydrogen peroxide signaling modulates neuronal differentiation via microglial polarization and Wnt/β-catenin pathway.
Engur D, Ercan I, Kiser C, Tufekci KU, Soy S, Micili SC, Ozhan G, Guven S, Kumral A, Genc S
European review for medical and pharmacological sciences 2023 Jun;27(11):5083-5096
European review for medical and pharmacological sciences 2023 Jun;27(11):5083-5096
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
miR-10a induces inflammatory responses in epileptic hippocampal neurons of rats via PI3K/Akt/mTOR signaling pathway.
Lu Y, Wang W, Ma Y, Fan Z, Xiong L, Zhao J, He Y, Li C, Wang A, Xiao N, Wang T
Neuroreport 2023 Jun 7;34(10):526-534
Neuroreport 2023 Jun 7;34(10):526-534
PACAP6-38 improves nitroglycerin-induced central sensitization by modulating synaptic plasticity at the trigeminal nucleus caudalis in a male rat model of chronic migraine.
Zhang L, Zhou Y, Yang L, Wang Y, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):66
The journal of headache and pain 2023 Jun 5;24(1):66
SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
Shan Z, Wang Y, Qiu T, Zhou Y, Zhang Y, Hu L, Zhang L, Liang J, Ding M, Fan S, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):65
The journal of headache and pain 2023 Jun 5;24(1):65
Role of the blood-spinal cord barrier: An adheren junction regulation mechanism that promotes chronic postsurgical pain.
Zhao Q, Yao J, Meng B, Shen S, Cao S
Biochemical and biophysical research communications 2023 Jun 11;660:65-72
Biochemical and biophysical research communications 2023 Jun 11;660:65-72
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Kong F, Zhang Y, Wang T, Zhong L, Feng C, Wu Y
The European journal of neuroscience 2023 Jan;57(2):217-232
The European journal of neuroscience 2023 Jan;57(2):217-232
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
Chen Y, Dong Y, Zhang ZL, Han J, Chen FS, Tong XY, Ma H
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13113
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13113
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Fang Q, Zheng S, Chen Q, Chen L, Yang Y, Wang Y, Zhang H, Chen J
Metabolic brain disease 2023 Feb;38(2):453-466
Metabolic brain disease 2023 Feb;38(2):453-466
ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.
Duan J, Yuan W, Jiang J, Wang J, Yan X, Liu F, Liu A
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Shu X, Wei C, Tu WY, Zhong K, Qi S, Wang A, Bai L, Zhang SX, Luo B, Xu ZZ, Zhang K, Shen C
Cell reports 2023 Feb 28;42(2):112133
Cell reports 2023 Feb 28;42(2):112133
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
Yan J, Liu T, Li Y, Zhang J, Shi B, Zhang F, Hou X, Zhang X, Cui W, Li J, Yao H, Li X, Gao Y, Jiang J
Aging 2023 Feb 28;15(4):1130-1142
Aging 2023 Feb 28;15(4):1130-1142
A versatile vessel casting method for fine mapping of vascular networks using a hydrogel-based lipophilic dye solution.
Zhu J, Liu X, Xu J, Deng Y, Wang P, Liu Z, Yang Q, Li D, Yu T, Zhu D
Cell reports methods 2023 Feb 27;3(2):100407
Cell reports methods 2023 Feb 27;3(2):100407
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
Guo D, Xu Y, Wang Y, Zhong X, Liu Z, Li S, Xu X, Zhang J, Xiong T, Cao W, Liang J
Behavioural brain research 2023 Feb 15;439:114223
Behavioural brain research 2023 Feb 15;439:114223
The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.
Li Y, Xu J, Guo X, Li Z, Cao L, Liu S, Guo Y, Wang G, Luo Y, Zhang Z, Wei X, Zhao Y, Liu T, Wang X, Xia H, Kuang M, Guo Q, Li J, Chen L, Wang Y, Li Q, Wang F, Liu Q, You F
Genome biology 2023 Feb 1;24(1):20
Genome biology 2023 Feb 1;24(1):20
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Liang P, Zhang X, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Liu W, Peng B, Yin J, He F, Fan Y, Han S, He X
Free radical biology & medicine 2023 Feb 1;195:329-342
Free radical biology & medicine 2023 Feb 1;195:329-342
Intracerebral Hemorrhage-Induced Brain Injury: the Role of Lysosomal-Associated Transmembrane Protein 5.
Hua W, Ma S, Pang Y, Liu Q, Wang Y, Liu Z, Zhao N, Ren N, Jin S, Wang B, Song Y, Qi J
Molecular neurobiology 2023 Dec;60(12):7060-7079
Molecular neurobiology 2023 Dec;60(12):7060-7079
Exercise ameliorates anxious behavior and promotes neuroprotection through osteocalcin in VCD-induced menopausal mice.
Kang Y, Yao J, Gao X, Zhong H, Song Y, Di X, Feng Z, Xie L, Zhang J
CNS neuroscience & therapeutics 2023 Dec;29(12):3980-3994
CNS neuroscience & therapeutics 2023 Dec;29(12):3980-3994
The NR2B-targeted intervention alleviates the neuronal injuries at the sub-acute stage of cerebral ischemia: an exploration of stage-dependent strategy against ischemic insults.
Guo B, Song H, Fan J, Wang B, Chen L, Hu Q, Yin Y
Experimental brain research 2023 Dec;241(11-12):2735-2750
Experimental brain research 2023 Dec;241(11-12):2735-2750
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Zhang YN, Wu Q, Zhang NN, Chen HS
Translational stroke research 2023 Dec;14(6):929-940
Translational stroke research 2023 Dec;14(6):929-940
Debris generated by laser and/or balloon cause cerebral infarction with different severity.
Yang K, Tan J, Deng Y, Jiang S, Tang J, Shi W, Yu B
Lasers in medical science 2023 Dec 23;39(1):15
Lasers in medical science 2023 Dec 23;39(1):15
Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury.
Dogan EO, Bouley J, Zhong J, Harkins AL, Keeler AM, Bosco DA, Brown RH Jr, Henninger N
Acta neuropathologica communications 2023 Dec 20;11(1):206
Acta neuropathologica communications 2023 Dec 20;11(1):206
Melatonin Protects Injured Spinal Cord Neurons From Apoptosis by Inhibiting Mitochondrial Damage via the SIRT1/Drp1 Signaling Pathway.
Zhong G, Yang Y, Feng D, Wei K, Chen J, Chen J, Deng C
Neuroscience 2023 Dec 1;534:54-65
Neuroscience 2023 Dec 1;534:54-65
Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice.
Kahriman A, Bouley J, Tuncali I, Dogan EO, Pereira M, Luu T, Bosco DA, Jaber S, Peters OM, Brown RH Jr, Henninger N
Brain : a journal of neurology 2023 Dec 1;146(12):5139-5152
Brain : a journal of neurology 2023 Dec 1;146(12):5139-5152
Knockdown of NADPH oxidase 4 reduces mitochondrial oxidative stress and neuronal pyroptosis following intracerebral hemorrhage.
Ding BY, Xie CN, Xie JY, Gao ZW, Fei XW, Hong EH, Chen WJ, Chen YZ
Neural regeneration research 2023 Aug;18(8):1734-1742
Neural regeneration research 2023 Aug;18(8):1734-1742
Dynamic Measurements of Cerebral Blood Flow Responses to Cortical Spreading Depolarization in the Murine Endovascular Perforation Subarachnoid Hemorrhage Model.
Yan J, Li W, Zhou C, Wu N, Yang X, Pan Q, He T, Wu Y, Guo Z, Xia Y, Sun X, Cheng C
Translational stroke research 2023 Aug;14(4):530-544
Translational stroke research 2023 Aug;14(4):530-544
Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response.
Godse S, Zhou L, Sinha N, Kodidela S, Kumar A, Singh UP, Kumar S
Research square 2023 Aug 9;
Research square 2023 Aug 9;
Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice.
Zhang X, Gao R, Zhang C, Teng Y, Chen H, Li Q, Liu C, Wu J, Wei L, Deng L, Wu L, Ye-Lehmann S, Mao X, Liu J, Zhu T, Chen C
Signal transduction and targeted therapy 2023 Aug 7;8(1):292
Signal transduction and targeted therapy 2023 Aug 7;8(1):292
LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis.
Sha L, Li J, Shen H, Wang Q, Meng P, Zhang X, Deng Y, Zhu W, Xu Q
Cell reports 2023 Aug 29;42(8):112975
Cell reports 2023 Aug 29;42(8):112975
GLP-1R agonist liraglutide attenuates pain hypersensitivity by stimulating IL-10 release in a nitroglycerin-induced chronic migraine mouse model.
Jing F, Zou Q, Pu Y
Neuroscience letters 2023 Aug 24;812:137397
Neuroscience letters 2023 Aug 24;812:137397
GABA(B) Receptor Activation Attenuates Neuronal Pyroptosis in Post-cardiac Arrest Brain Injury.
Sun Y, Li J, Wu H, Zhao Z, Cong T, Li L, Zhang X, Yin S, Xiao Z
Neuroscience 2023 Aug 21;526:97-106
Neuroscience 2023 Aug 21;526:97-106
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Ji L, Zhang L, Liang Z, Zhong S, Liu X, Liu Z, Poon WS, Song Y, Chen B, Wang R
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model.
Zhang L, Zhou Y, Wang Y, Yang L, Wang Y, Shan Z, Liang J, Xiao Z
Cephalalgia : an international journal of headache 2023 Apr;43(4):3331024231163131
Cephalalgia : an international journal of headache 2023 Apr;43(4):3331024231163131
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P, Jiang X, Zhang Q, Li L, Xie ST, Zhu JN, Hang C, Chen D, Liu X, Yan C
Nature neuroscience 2023 Apr;26(4):542-554
Nature neuroscience 2023 Apr;26(4):542-554
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction.
Xie J, Lv H, Liu X, Xia Z, Li J, Hong E, Ding B, Zhang W, Chen Y
Free radical biology & medicine 2023 Apr;199:67-80
Free radical biology & medicine 2023 Apr;199:67-80
Lactobacillus casei SYF-08 Protects Against Pb-Induced Injury in Young Mice by Regulating Bile Acid Metabolism and Increasing Pb Excretion.
Chen Z, Tang Z, Kong J, Chen L, Liu J, Li Y, Huang W, Li W, Wu J, Zhao W, Meng X, Fan H
Frontiers in nutrition 2022;9:914323
Frontiers in nutrition 2022;9:914323
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Rong ZJ, Cai HH, Wang H, Liu GH, Zhang ZW, Chen M, Huang YL
Frontiers in cellular neuroscience 2022;16:872935
Frontiers in cellular neuroscience 2022;16:872935
Lysosomal-associated transmembrane protein 5 deficiency exacerbates cerebral ischemia/reperfusion injury.
Zhang Z, Wang L, Wang Z, Zhang T, Shi M, Xin C, Zou Y, Wei W, Li X, Chen J, Zhao W
Frontiers in molecular neuroscience 2022;15:971361
Frontiers in molecular neuroscience 2022;15:971361
Young plasma reverses anesthesia and surgery-induced cognitive impairment in aged rats by modulating hippocampal synaptic plasticity.
Li Y, Zhang Q, Yan W, Wang X, Yu J, Yin C, Zhou Q, Hou Z, Wang Q
Frontiers in aging neuroscience 2022;14:996223
Frontiers in aging neuroscience 2022;14:996223
Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer's disease risk.
Qiu Y, Sha L, Zhang X, Li G, Zhu W, Xu Q
Frontiers in aging neuroscience 2022;14:896522
Frontiers in aging neuroscience 2022;14:896522
Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α-Syn and tau fragments.
Yang X, Wang J, Zeng W, Zhang X, Yang X, Xu Y, Xu Y, Cao X
Frontiers in aging neuroscience 2022;14:1049418
Frontiers in aging neuroscience 2022;14:1049418
Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity.
Li DD, Fan HX, Yang R, Li YY, Zhang F, Shi JS
Frontiers in pharmacology 2022;13:846541
Frontiers in pharmacology 2022;13:846541
Acute Administration of Metformin Protects Against Neuronal Apoptosis Induced by Cerebral Ischemia-Reperfusion Injury via Regulation of the AMPK/CREB/BDNF Pathway.
Liu K, Li L, Liu Z, Li G, Wu Y, Jiang X, Wang M, Chang Y, Jiang T, Luo J, Zhu J, Li H, Wang Y
Frontiers in pharmacology 2022;13:832611
Frontiers in pharmacology 2022;13:832611
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Zhang L, Zhang X, Liu Y, Wang S, Jia G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
Huang L, Sun X, Wang L, Pei G, Wang Y, Zhang Q, Liang Z, Wang D, Fu C, He C, Wei Q
MedComm 2022 Sep;3(3):e160
MedComm 2022 Sep;3(3):e160
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Chen J, Chang Y, Zhu J, Peng Y, Li Z, Zhang K, Zhang Y, Lin C, Lin Z, Pan S, Huang K
Journal of neuroinflammation 2022 Sep 1;19(1):214
Journal of neuroinflammation 2022 Sep 1;19(1):214
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Hu S, He L, Chen B, You Y
Peptides 2022 Oct;156:170847
Peptides 2022 Oct;156:170847
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
Ventrolateral Periaqueductal Gray Astrocytes Regulate Nociceptive Sensation and Emotional Motivation in Diabetic Neuropathic Pain.
Yang L, Lu J, Guo J, Chen J, Xiong F, Wang X, Chen L, Yu C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Oct 26;42(43):8184-8199
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Oct 26;42(43):8184-8199
Transfer of neuron-derived α-synuclein to astrocytes induces neuroinflammation and blood-brain barrier damage after methamphetamine exposure: Involving the regulation of nuclear receptor-associated protein 1.
Huang J, Ding J, Wang X, Gu C, He Y, Li Y, Fan H, Xie Q, Qi X, Wang Z, Qiu P
Brain, behavior, and immunity 2022 Nov;106:247-261
Brain, behavior, and immunity 2022 Nov;106:247-261
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
Zhang X, Liang P, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Peng B, Liu W, Yin J, Han S, He X
International journal of molecular sciences 2022 Nov 24;23(23)
International journal of molecular sciences 2022 Nov 24;23(23)
C1q and SRPX2 regulate microglia mediated synapse elimination during early development in the visual thalamus but not the visual cortex.
Cong Q, Soteros BM, Huo A, Li Y, Tenner AJ, Sia GM
Glia 2022 Mar;70(3):451-465
Glia 2022 Mar;70(3):451-465
PDK4 Decrease Neuronal Apoptosis via Inhibiting ROS-ASK1/P38 Pathway in Early Brain Injury After Subarachnoid Hemorrhage.
Gao X, Gao YY, Yan HY, Liu GJ, Zhou Y, Tao T, Yue TT, Pang C, Chen XX, Gao S, Wu LY, Hang CH, Li W
Antioxidants & redox signaling 2022 Mar;36(7-9):505-524
Antioxidants & redox signaling 2022 Mar;36(7-9):505-524
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952
Experimental neurology 2022 Mar;349:113952
Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation.
Xu L, Sun Z, Xing Z, Liu Y, Zhao H, Tang Z, Luo Y, Hao S, Li K
Journal of nanobiotechnology 2022 Mar 9;20(1):118
Journal of nanobiotechnology 2022 Mar 9;20(1):118
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Wang T, Xu J, Xu Y, Xiao J, Bi N, Gu X, Wang HL
Cell reports 2022 Mar 8;38(10):110478
Cell reports 2022 Mar 8;38(10):110478
Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.
Yang L, Wu C, Li Y, Dong Y, Wu CY, Lee RH, Brann DW, Lin HW, Zhang Q
GeroScience 2022 Jun;44(3):1457-1477
GeroScience 2022 Jun;44(3):1457-1477
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Zhang D, Ren Y, He Y, Chang R, Guo S, Ma S, Guan F, Yao M
Materials today. Bio 2022 Jun;15:100278
Materials today. Bio 2022 Jun;15:100278
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice.
Ni Y, Feng Y, Shen D, Chen M, Zhu X, Zhou Q, Gao Y, Liu J, Zhang Q, Shen Y, Peng L, Zeng Z, Yin D, Hu J, Chen S
Journal of neuroinflammation 2022 Jun 11;19(1):140
Journal of neuroinflammation 2022 Jun 11;19(1):140
Icariin attenuates ischaemic stroke through suppressing inflammation mediated by endoplasmic reticulum stress signalling pathway in rats.
Zheng J, Liao Y, Xu Y, Mo Z
Clinical and experimental pharmacology & physiology 2022 Jul;49(7):719-730
Clinical and experimental pharmacology & physiology 2022 Jul;49(7):719-730
Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment.
Lan L, Wang H, Zhang X, Shen Q, Li X, He L, Rong X, Peng J, Mo J, Peng Y
Experimental neurology 2022 Jul;353:114061
Experimental neurology 2022 Jul;353:114061
High Expression of PDK4 Could Play a Potentially Protective Role by Attenuating Oxidative Stress after Subarachnoid Hemorrhage.
Gao X, Gao YY, Wu LY, Peng Z, Liu XZ, Chen XX, Gao S, Zhang HS, Lu Y, Hang CH, Zhuang Z, Li W
Journal of clinical medicine 2022 Jul 8;11(14)
Journal of clinical medicine 2022 Jul 8;11(14)
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Wang L, Zhang D, Ren Y, Guo S, Li J, Ma S, Yao M, Guan F
Materials today. Bio 2022 Jan;13:100201
Materials today. Bio 2022 Jan;13:100201
The decreased expression of miR-429 in plasma exosomes after spinal cord injury inhibits neuronal apoptosis by mediating the PTEN/PI3K/Akt pathway.
Huang J, Wu C, Xu G, Sun Y, Gui C, Fu J, Cui Z, Huang H
Annals of translational medicine 2022 Jan;10(1):6
Annals of translational medicine 2022 Jan;10(1):6
Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice.
Yang N, Liu X, Niu X, Wang X, Jiang R, Yuan N, Wang J, Zhang C, Lim KL, Lu L
Stem cell reviews and reports 2022 Feb;18(2):626-641
Stem cell reviews and reports 2022 Feb;18(2):626-641
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Tang H, Li J, Zhou Q, Li S, Xie C, Niu L, Ma J, Li C
Cell death discovery 2022 Feb 8;8(1):54
Cell death discovery 2022 Feb 8;8(1):54
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Lu T, Li H, Zhou Y, Wei W, Ding L, Zhan Z, Liu W, Tao J, Xue X
Journal of neuroinflammation 2022 Feb 7;19(1):37
Journal of neuroinflammation 2022 Feb 7;19(1):37
Anatomical and behavioral outcomes following a graded hemi-contusive cervical spinal cord injury model in mice.
Huang Z, Huang Z, Kong G, Lin J, Liu J, Yang Z, Li R, Wu X, Alaeiilkhchi N, Jiang H, Liu J, Wu X, Zhu Q
Behavioural brain research 2022 Feb 15;419:113698
Behavioural brain research 2022 Feb 15;419:113698
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
Zhang Y, Kuai S, Zhang Y, Xue H, Wu Z, Zhao P
Neurotoxicology 2022 Dec;93:348-354
Neurotoxicology 2022 Dec;93:348-354
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
Caveolin-1 suppresses hippocampal neuron apoptosis via the regulation of HIF1α in hypoxia in naked mole-rats.
Yang W, Wu W, Zhao Y, Li Y, Zhang C, Zhang J, Chen C, Cui S
Cell biology international 2022 Dec;46(12):2060-2074
Cell biology international 2022 Dec;46(12):2060-2074
Identification and expression profile of novel STAND gene Nwd2 in the mouse central nervous system.
Yamada S, Furukawa R, Sakakibara SI
Gene expression patterns : GEP 2022 Dec;46:119284
Gene expression patterns : GEP 2022 Dec;46:119284
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Zhang N, Shentu Y, Zhu M, Wang H, Yin X, Du C, Xue F, Fan J, Gong Y, Fan X
Brain research 2022 Dec 15;1797:148117
Brain research 2022 Dec 15;1797:148117
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Kong X, Shu X, Wang J, Liu D, Ni Y, Zhao W, Wang L, Gao Z, Chen J, Yang B, Guo X, Wang Z
Development (Cambridge, England) 2022 Dec 15;149(24)
Development (Cambridge, England) 2022 Dec 15;149(24)
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
Yang C, Kang F, Huang X, Zhang W, Wang S, Han M, Zhang Z, Li J
Neuropharmacology 2022 Dec 1;220:109254
Neuropharmacology 2022 Dec 1;220:109254
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Li J, Bu Y, Li B, Zhang H, Guo J, Hu J, Zhang Y
Journal of molecular histology 2022 Aug;53(4):713-727
Journal of molecular histology 2022 Aug;53(4):713-727
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
Fang Q, Liu J, Chen L, Chen Q, Wang Y, Li Z, Fu W, Liu Y
Metabolic brain disease 2022 Aug;37(6):2077-2088
Metabolic brain disease 2022 Aug;37(6):2077-2088
Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain.
McCollum MM, Larmore M, Ishihara S, Ng LCT, Kimura LF, Guadarrama E, Ta MC, Vien TN, Frost GB, Scheidt KA, Miller RE, DeCaen PG
Cell reports 2022 Aug 23;40(8):111248
Cell reports 2022 Aug 23;40(8):111248
Astrocytic CD24 Protects Neuron from Recombinant High-Mobility Group Box 1 Protein(rHMGB1)-Elicited Neuronal Injury.
Pang C, Gao S, Liu XZ, Li XJ, Peng Z, Zhang HS, Zhou Y, Chen XX, Tao T, Lu Y, Li W, Hang CH
Brain sciences 2022 Aug 23;12(9)
Brain sciences 2022 Aug 23;12(9)
Single-atom nanozymes catalytically surpassing naturally occurring enzymes as sustained stitching for brain trauma.
Zhang S, Li Y, Sun S, Liu L, Mu X, Liu S, Jiao M, Chen X, Chen K, Ma H, Li T, Liu X, Wang H, Zhang J, Yang J, Zhang XD
Nature communications 2022 Aug 12;13(1):4744
Nature communications 2022 Aug 12;13(1):4744
Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation.
Hou M, Wang S, Yu D, Lu X, Zhao X, Chen Z, Yan C
Frontiers of medicine 2022 Apr;16(2):227-239
Frontiers of medicine 2022 Apr;16(2):227-239
FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model.
Cornille M, Moriceau S, Khonsari RH, Heuzé Y, Loisay L, Boitez V, Morice A, Arnaud E, Collet C, Bensidhoum M, Kaci N, Boddaert N, Paternoster G, Rauschendorfer T, Werner S, Mansour SL, Di Rocco F, Oury F, Legeai-Mallet L
The Journal of experimental medicine 2022 Apr 4;219(4)
The Journal of experimental medicine 2022 Apr 4;219(4)
High altitude is associated with pTau deposition, neuroinflammation, and myelin loss.
Iacono D, Murphy EK, Sherman PM, Chapapas H, Cerqueira B, Christensen C, Perl DP, Sladky J
Scientific reports 2022 Apr 27;12(1):6839
Scientific reports 2022 Apr 27;12(1):6839
GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.
Yu S, Li Z, Zhang Q, Wang R, Zhao Z, Ding W, Wang F, Sun C, Tang J, Wang X, Zhang H, Huang R, Wu Q, Jiang J, Zhao X
Ecotoxicology and environmental safety 2022 Apr 1;234:113413
Ecotoxicology and environmental safety 2022 Apr 1;234:113413
Homoharringtonine Inhibits Alzheimer's Disease Progression by Reducing Neuroinflammation via STAT3 Signaling in APP/PS1 Mice.
Jiang X, Wu Q, Zhang C, Wang M
Neuro-degenerative diseases 2021;21(3-4):93-102
Neuro-degenerative diseases 2021;21(3-4):93-102
Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression.
Zhang D, Shen Q, Wu X, Xing D
Oxidative medicine and cellular longevity 2021;2021:6678276
Oxidative medicine and cellular longevity 2021;2021:6678276
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
Alvites RD, Branquinho MV, Sousa AC, Amorim I, Magalhães R, João F, Almeida D, Amado S, Prada J, Pires I, Zen F, Raimondo S, Luís AL, Geuna S, Varejão ASP, Maurício AC
Stem cells international 2021;2021:6613029
Stem cells international 2021;2021:6613029
Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques.
Scardigli M, Pesce L, Brady N, Mazzamuto G, Gavryusev V, Silvestri L, Hof PR, Destrieux C, Costantini I, Pavone FS
Frontiers in neuroanatomy 2021;15:752234
Frontiers in neuroanatomy 2021;15:752234
Deficits in N-Methyl-D-Aspartate Receptor Function and Synaptic Plasticity in Hippocampal CA1 in APP/PS1 Mouse Model of Alzheimer's Disease.
Xu L, Zhou Y, Hu L, Jiang H, Dong Y, Shen H, Lou Z, Yang S, Ji Y, Ruan L, Zhang X
Frontiers in aging neuroscience 2021;13:772980
Frontiers in aging neuroscience 2021;13:772980
Yi-Zhi-Fang-Dai Formula Exerts Neuroprotective Effects Against Pyroptosis and Blood-Brain Barrier-Glymphatic Dysfunctions to Prevent Amyloid-Beta Acute Accumulation After Cerebral Ischemia and Reperfusion in Rats.
Lyu Z, Li Q, Yu Z, Chan Y, Fu L, Li Y, Zhang C
Frontiers in pharmacology 2021;12:791059
Frontiers in pharmacology 2021;12:791059
Integrated Bioinformatics Analysis of Potential mRNA and miRNA Regulatory Networks in Mice With Ischemic Stroke Treated by Electroacupuncture.
Wu C, Zhao L, Li X, Xu Y, Guo H, Huang Z, Wang Q, Liu H, Chen D, Zhu M
Frontiers in neurology 2021;12:719354
Frontiers in neurology 2021;12:719354
Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior.
Saito Y, Miyajima M, Yamamoto S, Sato T, Miura N, Fujimiya M, Chikenji TS
Frontiers in immunology 2021;12:692321
Frontiers in immunology 2021;12:692321
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Yang L, Dong Y, Wu C, Youngblood H, Li Y, Zong X, Li L, Xu T, Zhang Q
Theranostics 2021;11(3):1269-1294
Theranostics 2021;11(3):1269-1294
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181
Scientific reports 2021 Sep 13;11(1):18181
Sodium alginate/collagen/stromal cell-derived factor-1 neural scaffold loaded with BMSCs promotes neurological function recovery after traumatic brain injury.
Ma S, Zhou J, Huang T, Zhang Z, Xing Q, Zhou X, Zhang K, Yao M, Cheng T, Wang X, Wen X, Guan F
Acta biomaterialia 2021 Sep 1;131:185-197
Acta biomaterialia 2021 Sep 1;131:185-197
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Tan X, Guo W, Peng Z, Gu C, Xiang P, Tu Y, Fei H, Liu X, Lu Y, Li M, Wang H, Luo Y, Yang J
Biochemical pharmacology 2021 Oct;192:114694
Biochemical pharmacology 2021 Oct;192:114694
Bifidobacterium adolescentis regulates catalase activity and host metabolism and improves healthspan and lifespan in multiple species.
Chen S, Chen L, Qi Y, Xu J, Ge Q, Fan Y, Chen D, Zhang Y, Wang L, Hou T, Yang X, Xi Y, Si J, Kang L, Wang L
Nature aging 2021 Nov;1(11):991-1001
Nature aging 2021 Nov;1(11):991-1001
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Zhang L, Liu Y, Wang S, Long L, Zang Q, Ma J, Yu L, Jia G
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Huntingtin silencing delays onset and slows progression of Huntington's disease: a biomarker study.
Liu H, Zhang C, Xu J, Jin J, Cheng L, Miao X, Wu Q, Wei Z, Liu P, Lu H, van Zijl PCM, Ross CA, Hua J, Duan W
Brain : a journal of neurology 2021 Nov 29;144(10):3101-3113
Brain : a journal of neurology 2021 Nov 29;144(10):3101-3113
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Raber J, Perez R, Torres ERS, Krenik D, Boutros S, Patel E, Chlebowski AC, Torres ER, Perveen Z, Penn A, Paulsen DB, Bartlett MG, Jia E, Holden S, Hall R, Morré J, Wong C, Ho E, Choi J, Stevens JF, Noël A, Bobe G, Kisby G
Environmental health perspectives 2021 May;129(5):57009
Environmental health perspectives 2021 May;129(5):57009
Nuclear PTEN deficiency and heterozygous PTEN loss have distinct impacts on brain and lymph node size.
Igarashi A, Kato T, Sesaki H, Iijima M
Biochemical and biophysical research communications 2021 May 28;555:81-88
Biochemical and biophysical research communications 2021 May 28;555:81-88
Tak1 in the astrocytes of mediobasal hypothalamus regulates anxiety-like behavior in mice.
Zhao F, Zhang T, Shen Q, Yin K, Wang Y, Zhang G
Glia 2021 Mar;69(3):609-618
Glia 2021 Mar;69(3):609-618
Blunted diurnal firing in lateral habenula projections to dorsal raphe nucleus and delayed photoentrainment in stress-susceptible mice.
Liu H, Rastogi A, Narain P, Xu Q, Sabanovic M, Alhammadi AD, Guo L, Cao JL, Zhang H, Aqel H, Mlambo V, Rezgui R, Radwan B, Chaudhury D
PLoS biology 2021 Mar;19(3):e3000709
PLoS biology 2021 Mar;19(3):e3000709
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature.
Kahriman A, Bouley J, Smith TW, Bosco DA, Woerman AL, Henninger N
Acta neuropathologica communications 2021 Jun 29;9(1):118
Acta neuropathologica communications 2021 Jun 29;9(1):118
Congenital hypothyroidism impairs spine growth of dentate granule cells by downregulation of CaMKIV.
Tang Q, Chen S, Wu H, Song H, Wang Y, Shi J, Wu Y
Cell death discovery 2021 Jun 14;7(1):143
Cell death discovery 2021 Jun 14;7(1):143
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Deng L, Guo Y, Liu J, Wang X, Chen S, Wang Q, Rao J, Wang Y, Zuo T, Hu Q, Zhao X, Dong Z
Neurochemical research 2021 Jul;46(7):1801-1813
Neurochemical research 2021 Jul;46(7):1801-1813
MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cord.
Sun L, Xia R, Jiang J, Wen T, Huang Z, Qian R, Zhang MD, Zhou M, Peng C
Progress in neurobiology 2021 Jul;202:102024
Progress in neurobiology 2021 Jul;202:102024
Targeting senescent cells improves functional recovery after spinal cord injury.
Paramos-de-Carvalho D, Martins I, Cristóvão AM, Dias AF, Neves-Silva D, Pereira T, Chapela D, Farinho A, Jacinto A, Saúde L
Cell reports 2021 Jul 6;36(1):109334
Cell reports 2021 Jul 6;36(1):109334
Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation.
Jing F, Zou Q, Wang Y, Cai Z, Tang Y
The journal of headache and pain 2021 Jul 29;22(1):86
The journal of headache and pain 2021 Jul 29;22(1):86
CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome.
Asamitsu S, Yabuki Y, Ikenoshita S, Kawakubo K, Kawasaki M, Usuki S, Nakayama Y, Adachi K, Kugoh H, Ishii K, Matsuura T, Nanba E, Sugiyama H, Fukunaga K, Shioda N
Science advances 2021 Jan;7(3)
Science advances 2021 Jan;7(3)
Genetic deletion of Rnd3 suppresses apoptosis through NF‑κB signaling in the brain.
Dong H, Sun Q, Zhang Y, Li Y, Yuan F, Mao S, Liu B
Oncology reports 2021 Feb;45(2):595-605
Oncology reports 2021 Feb;45(2):595-605
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Cui F, Pan Q, Wang S, Zhao F, Wang R, Zhang T, Song Y, He J, Zhang H, Weng Q, Jin Y, Xia W, Li Y, Yang GY, De Vos WH, Timmermans JP, Xu S, Tang Y, Sheng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Dec;8(23):e2102686
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Dec;8(23):e2102686
An injury-induced serotonergic neuron subpopulation contributes to axon regrowth and function restoration after spinal cord injury in zebrafish.
Huang CX, Zhao Y, Mao J, Wang Z, Xu L, Cheng J, Guan NN, Song J
Nature communications 2021 Dec 7;12(1):7093
Nature communications 2021 Dec 7;12(1):7093
Acute hypoxia elevates arginase 2 and induces polyamine stress response in zebrafish via evolutionarily conserved mechanism.
Banerjee B, Khrystoforova I, Polis B, Zvi IB, Karasik D
Cellular and molecular life sciences : CMLS 2021 Dec 16;79(1):41
Cellular and molecular life sciences : CMLS 2021 Dec 16;79(1):41
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Peng G, Zheng H, Wu C, Wu C, Ma X, Xiong J, Hou J, Zhang L, Yang L, Pan H
Brain research 2021 Dec 1;1772:147665
Brain research 2021 Dec 1;1772:147665
Simvastatin-Ezetimibe enhances growth factor expression and attenuates neuron loss in the hippocampus in a model of intracerebral hemorrhage.
Wang KW, Liang CL, Yeh LR, Liu KY, Chen CC, Chen JS, Chen HJ, Wang HK
Fundamental & clinical pharmacology 2021 Aug;35(4):634-644
Fundamental & clinical pharmacology 2021 Aug;35(4):634-644
Brain network reorganization after targeted attack at a hub region.
Tu W, Ma Z, Zhang N
NeuroImage 2021 Aug 15;237:118219
NeuroImage 2021 Aug 15;237:118219
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, Wei Y, Liu H, Ma L, Li H, You C, Tian M
Frontiers in bioengineering and biotechnology 2020;8:785
Frontiers in bioengineering and biotechnology 2020;8:785
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis.
Deng Y, Yang L, Xie Q, Yang F, Li G, Zhang G, Li S, Wu Z, Wang J, Kang X
Mediators of inflammation 2020;2020:6420425
Mediators of inflammation 2020;2020:6420425
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Xie J, Hong E, Ding B, Jiang W, Zheng S, Xie Z, Tian D, Chen Y
Frontiers in cellular neuroscience 2020;14:578060
Frontiers in cellular neuroscience 2020;14:578060
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Yang F, Wang H, Chen H, Ran D, Tang Q, Weng P, Sun Y, Jiang W
Brain research bulletin 2020 Oct;163:49-56
Brain research bulletin 2020 Oct;163:49-56
Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury.
Polcyn R, Capone M, Matzelle D, Hossain A, Chandran R, Banik NL, Haque A
Neurochemistry international 2020 Oct;139:104788
Neurochemistry international 2020 Oct;139:104788
Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.
Asamitsu S, Imai Y, Yabuki Y, Ikenoshita S, Takeuchi M, Kashiwagi H, Tanoue Y, Fukuda T, Shioda N
Biochemical and biophysical research communications 2020 Oct 8;531(1):67-74
Biochemical and biophysical research communications 2020 Oct 8;531(1):67-74
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Ouyang L, Mu X, Wang J, Li Q, Gao Y, Liu H, Sun S, Ren Q, Yan R, Wang J, Liu Q, Sun Y, Liu C, He H, Long W, Zhang XD
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
HCN2 contributes to oxaliplatin-induced neuropathic pain by inducing spinal long-term potentiation via activation of NMDA receptor-mediated CaMKII signaling.
Liu X, Ji Q, Liu F, Jin L, Tan Y, Zhang L, Tang J
Brain research bulletin 2020 Jun;159:61-66
Brain research bulletin 2020 Jun;159:61-66
Let-7b-5p promotes electroacupuncture tolerance by downregulating Penk1 gene in CFA-induced inflammatory nociception rats.
Zhang Q, Liu A, Abouelfetouh MM, Ma N, Li M, Chen S, Ding M, Ding Y
Gene 2020 Jun 5;742:144583
Gene 2020 Jun 5;742:144583
miR-211-5p alleviates focal cerebral ischemia-reperfusion injury in rats by down-regulating the expression of COX2.
Peng Z, Li M, Tan X, Xiang P, Wang H, Luo Y, Yang Y, Huang H, Chen Z, Xia H, Li Y, Zhang J, Gu C, Liu M, Wang Q, Chen M, Yang J
Biochemical pharmacology 2020 Jul;177:113983
Biochemical pharmacology 2020 Jul;177:113983
Glimepiride and glibenclamide have comparable efficacy in treating acute ischemic stroke in mice.
Wang X, Chang Y, He Y, Lyu C, Li H, Zhu J, Liu K, Hu Y, Huang K, Pan S
Neuropharmacology 2020 Jan 1;162:107845
Neuropharmacology 2020 Jan 1;162:107845
Expression of p16 and p21 in the frontal association cortex of ALS/MND brains suggests neuronal cell cycle dysregulation and astrocyte senescence in early stages of the disease.
Vazquez-Villaseñor I, Garwood CJ, Heath PR, Simpson JE, Ince PG, Wharton SB
Neuropathology and applied neurobiology 2020 Feb;46(2):171-185
Neuropathology and applied neurobiology 2020 Feb;46(2):171-185
The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury.
Huang YF, Gu CJ, Wang Q, Xu L, Chen J, Zhou W, Zhou Z, Zhao SJ, Li LW, Kong FQ, Qian DF, Zhao X, Fan J, Li QQ, Yin GY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2055-2074
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2055-2074
Sepsis induced cognitive impairments by disrupting hippocampal parvalbumin interneuron-mediated inhibitory network via a D4-receptor mechanism.
Ji M, Li S, Zhang L, Gao Y, Zeng Q, Mao M, Yang J
Aging 2020 Feb 4;12(3):2471-2484
Aging 2020 Feb 4;12(3):2471-2484
Positive regulation of the CREB phosphorylation via JNK-dependent pathway prevents antimony-induced neuronal apoptosis in PC12 cell and mice brain.
Zhi Y, Lu C, Zhu G, Li Z, Zhu P, Liu Y, Shi W, Su L, Jiang J, Qu J, Zhao X
Neurotoxicology 2020 Dec;81:101-108
Neurotoxicology 2020 Dec;81:101-108
Baicalein Ameliorates Epilepsy Symptoms in a Pilocarpine-Induced Rat Model by Regulation of IGF1R.
Fu P, Yuan Q, Sun Y, Wu X, Du Z, Li Z, Yu J, Lv K, Hu J
Neurochemical research 2020 Dec;45(12):3021-3033
Neurochemical research 2020 Dec;45(12):3021-3033
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
Yang J, Cao H, Guo S, Zhu H, Tao H, Zhang L, Chen Z, Sun T, Chi S, Hu Q
Molecular medicine reports 2020 Dec;22(6):4763-4771
Molecular medicine reports 2020 Dec;22(6):4763-4771
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, Cheng C, Wang G, Sun X
Neuroscience 2020 Aug 1;440:160-174
Neuroscience 2020 Aug 1;440:160-174
Overinhibition mediated by parvalbumin interneurons might contribute to depression-like behavior and working memory impairment induced by lipopolysaccharide challenge.
Ji MH, Zhang L, Mao MJ, Zhang H, Yang JJ, Qiu LL
Behavioural brain research 2020 Apr 6;383:112509
Behavioural brain research 2020 Apr 6;383:112509
Decreased Netrin-1 and Correlated Th17/Tregs Balance Disorder in Aβ(1-42) Induced Alzheimer's Disease Model Rats.
Sun L, Ju T, Wang T, Zhang L, Ding F, Zhang Y, An R, Sun Y, Li Y, Lu Y, Zhang X, Chi L
Frontiers in aging neuroscience 2019;11:124
Frontiers in aging neuroscience 2019;11:124
Ellagic acid supports neuron by regulating astroglia Nrf2.
Wang GQ, He XM, Zhu GF, Li DD, Shi JS, Zhang F
Biotechnology and applied biochemistry 2019 Sep;66(5):738-743
Biotechnology and applied biochemistry 2019 Sep;66(5):738-743
Antimony, a novel nerve poison, triggers neuronal autophagic death via reactive oxygen species-mediated inhibition of the protein kinase B/mammalian target of rapamycin pathway.
Wang X, Zhu P, Xu S, Liu Y, Jin Y, Yu S, Wei H, Li J, Zhang Q, Hasegawa T, Yao C, Yoshimura H, Wu Q, Zhao X
The international journal of biochemistry & cell biology 2019 Sep;114:105561
The international journal of biochemistry & cell biology 2019 Sep;114:105561
A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats.
Yao M, Gao F, Xu R, Zhang J, Chen Y, Guan F
Biomaterials science 2019 Sep 24;7(10):4088-4098
Biomaterials science 2019 Sep 24;7(10):4088-4098
Circular RNA TLK1 Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP.
Wu F, Han B, Wu S, Yang L, Leng S, Li M, Liao J, Wang G, Ye Q, Zhang Y, Chen H, Chen X, Zhong M, Xu Y, Liu Q, Zhang JH, Yao H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Sep 11;39(37):7369-7393
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Sep 11;39(37):7369-7393
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
Yang Y, Shi Y, Jia J, Wang S, Chang H, Li M, Jin X, Wang J
Neurological research 2019 Oct;41(10):900-908
Neurological research 2019 Oct;41(10):900-908
DHEA Attenuates Microglial Activation via Induction of JMJD3 in Experimental Subarachnoid Haemorrhage.
Tao T, Liu GJ, Shi X, Zhou Y, Lu Y, Gao YY, Zhang XS, Wang H, Wu LY, Chen CL, Zhuang Z, Li W, Hang CH
Journal of neuroinflammation 2019 Nov 28;16(1):243
Journal of neuroinflammation 2019 Nov 28;16(1):243
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
Mo J, Wang B, Zhu X, Wu X, Liu Y
Neurobiology of disease 2019 Jan;121:274-285
Neurobiology of disease 2019 Jan;121:274-285
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Guan F, Zhou X, Li P, Wang Y, Liu M, Li F, Cui Y, Huang T, Yao M, Zhang Y, Ma J, Ma S
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial biogenesis.
Chen S, Sun M, Zhao X, Yang Z, Liu W, Cao J, Qiao Y, Luo X, Wen A
Molecular medicine reports 2019 Apr;19(4):3009-3020
Molecular medicine reports 2019 Apr;19(4):3009-3020
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Xu L, Xing Q, Huang T, Zhou J, Liu T, Cui Y, Cheng T, Wang Y, Zhou X, Yang B, Yang GL, Zhang J, Zang X, Ma S, Guan F
Frontiers in cellular neuroscience 2018;12:498
Frontiers in cellular neuroscience 2018;12:498
Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility.
Igarashi A, Itoh K, Yamada T, Adachi Y, Kato T, Murata D, Sesaki H, Iijima M
The Journal of biological chemistry 2018 Jun 15;293(24):9292-9300
The Journal of biological chemistry 2018 Jun 15;293(24):9292-9300
Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure.
Wang W, Lu H, Lu X, Wang D, Wang Z, Dai W, Wang J, Liu P
Journal of neuroinflammation 2018 Aug 22;15(1):234
Journal of neuroinflammation 2018 Aug 22;15(1):234
Up-regulation of MCM3 Relates to Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats.
Ji W, Liu H, Liu C, Shao L, Liu Y, Fan S, Li X, Gong LL, Zhu S, Gao Y
Cellular and molecular neurobiology 2017 May;37(4):683-693
Cellular and molecular neurobiology 2017 May;37(4):683-693
Human Umbilical Cord Mesenchymal Stem Cells Overexpressing Nerve Growth Factor Ameliorate Diabetic Cystopathy in Rats.
WenBo W, Fei Z, YiHeng D, Wei W, TingMang Y, WenHao Z, QianRu L, HaiTao L
Neurochemical research 2017 Dec;42(12):3537-3547
Neurochemical research 2017 Dec;42(12):3537-3547
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