Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15579-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15579-1-AP, RRID:AB_2737362
- Product name
- CBX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CBX2 antibody (Cat. #15579-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CBX2 Deletion Suppresses Growth and Metastasis of Colorectal Cancer by Mettl3-p38/ERK MAPK Signalling Pathway.
Derepressing of STAT3 and USP7 contributes to resistance of DLBCL to EZH2 inhibition.
Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells.
Comprehensive analysis reveals the value of the expression of chromobox family members for bladder urothelial carcinoma prognosis.
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Sun R, Tu X, Chan S, Wang X, Ji Y, Wang Z, Yu Z, Zuo X, Zhang Q, Chen J, Han Q, Wang M, Zhao H, Zhang H, Chen W
Journal of Cancer 2024;15(8):2123-2136
Journal of Cancer 2024;15(8):2123-2136
Derepressing of STAT3 and USP7 contributes to resistance of DLBCL to EZH2 inhibition.
He C, Zhou W, Jin X, Zhou H
Heliyon 2023 Oct;9(10):e20650
Heliyon 2023 Oct;9(10):e20650
Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells.
Ma Y, Liu L, Wei Z, Zhu M, Huang L, Wang S, Yi X, Ying F, Zhao S, Cai J, Wang Z, Sun S
Molecular carcinogenesis 2023 Apr;62(4):479-492
Molecular carcinogenesis 2023 Apr;62(4):479-492
Comprehensive analysis reveals the value of the expression of chromobox family members for bladder urothelial carcinoma prognosis.
Meng X, Cao R, Liu X, Fu B, Luo L, Jiang M, Wang K, Liu Y, Zhu Q, Yang C, Zhou L
Oncology letters 2023 Apr;25(4):172
Oncology letters 2023 Apr;25(4):172
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
Zhou H, Feng W, Yu J, Shafiq TA, Paulo JA, Zhang J, Luo Z, Gygi SP, Moazed D
Cell reports 2023 Apr 25;42(4):112339
Cell reports 2023 Apr 25;42(4):112339
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
Zheng S, Lv P, Su J, Miao K, Xu H, Li M
American journal of translational research 2019;11(3):1668-1682
American journal of translational research 2019;11(3):1668-1682
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The CBX2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CBX2. This antibody recognizes human, mouse, rat antigen. The CBX2 antibody has been validated for the following applications: ELISA, WB analysis.