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- References [11]
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- Product number
- 18972-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18972-1-AP, RRID:AB_2159196
- Product name
- PAOX antibody
- Antibody type
- Polyclonal
- Description
- PAOX antibody (Cat. #18972-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeted Accumulation of Reactive Acrolein via Nanoparticle-embedded Reverse Temperature Hydrogel for Bladder Cancer Treatment.
Polyamine-dependent metabolic shielding regulates alternative splicing.
Effects of spermine on osteoblasts during iron deficiency in vitro and in vivo during chronic kidney disease.
Targeting polyamine metabolism induces oxidative/carbonyl stress to reinvigorate antitumor immunity in prostate cancer.
NF-E2-related factor 1 suppresses the expression of a spermine oxidase and the production of highly reactive acrolein.
Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils.
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Regulation of Spermine Oxidase through Hypoxia-Inducible Factor-1α Signaling in Retinal Glial Cells under Hypoxic Conditions.
Xu Y, Du Q, Zhao Z, Fu S, Zhang A, Zheng J, Zhao C, Meng Y, Liu H, Lv Z, Qin X, Geng H, Yu N
Theranostics 2026;16(3):1528-1544
Theranostics 2026;16(3):1528-1544
Polyamine-dependent metabolic shielding regulates alternative splicing.
Zabala-Letona A, Pujana-Vaquerizo M, Martinez-Laosa B, Ponce-Rodriguez M, Garcia-Longarte S, Mendizabal I, Gimeno A, Rogalska M, Tan J, Cabrera D, van Liempd S, Ximenez-Embun P, Espinosa S, Fagoaga-Eugui M, Peccati F, Zakrzewski M, Astobiza I, Arana-Castañares M, Cherkaoui S, Sendino M, Martín-Barros I, Ercilla A, Bozal-Basterra L, Carlevaris O, Arruabarrena-Aristorena A, Pérez-Andrés E, Santamaría-Zamorano T, Ferrer-Bonsoms JA, Carazo F, Cieśla M, Lobato C, Seoane J, Martín-Martín N, Barrio R, Sutherland JD, Aransay AM, Falcón-Pérez JM, Martínez-Pastor B, Rubio A, Blanco FJ, Hogarty MD, Morscher RJ, Berra E, Serwa RA, Jiménez-Barbero J, Jiménez-Osés G, Efeyan A, Finley L, Lizcano JM, Muñoz J, Valcarcel J, Carracedo A
Nature 2026 Mar;651(8106):819-828
Nature 2026 Mar;651(8106):819-828
Effects of spermine on osteoblasts during iron deficiency in vitro and in vivo during chronic kidney disease.
Miller C, Segvich DM, Wanner J, Mahmood H, Kirschner KM, Matz JA, Santangelo S, Wallace JM, Clinkenbeard EL
Bone 2026 Jul;208:117867
Bone 2026 Jul;208:117867
Targeting polyamine metabolism induces oxidative/carbonyl stress to reinvigorate antitumor immunity in prostate cancer.
Zhang A, Zheng J, Xu Y, Fu S, Du Q, Zhao C, Meng Y, Li M, Wang L, Wang S, Shi T, Yang C, Jiang P, Wang Y, Zhao Z, Zhang Z, Zhao S, Qin X, Geng H, Yu N
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114283
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114283
NF-E2-related factor 1 suppresses the expression of a spermine oxidase and the production of highly reactive acrolein.
Hirakawa T, Taniuchi M, Iguchi Y, Bogahawaththa S, Yoshitake K, Werellagama S, Uemura T, Tsujita T
Scientific reports 2025 Apr 21;15(1):12405
Scientific reports 2025 Apr 21;15(1):12405
Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.
Han X, Wang D, Yang L, Wang N, Shen J, Wang J, Zhang L, Chen L, Gao S, Zong WX, Wang Y
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 26;121(13):e2319429121
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 26;121(13):e2319429121
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
Wei W, Lu Y, Zhang M, Guo J, Zhang H
Scientific reports 2024 Aug 5;14(1):18094
Scientific reports 2024 Aug 5;14(1):18094
Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils.
Kato M, Maeda K, Nakahara R, Hirose H, Kondo A, Aki S, Sugaya M, Hibino S, Nishida M, Hasegawa M, Morita H, Ando R, Tsuchida R, Yoshida M, Kodama T, Yanai H, Shimamura T, Osawa T
PNAS nexus 2023 Oct;2(10):pgad306
PNAS nexus 2023 Oct;2(10):pgad306
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Halloran KM, Stenhouse C, Moses RM, Seo H, Johnson GA, Wu G, Bazer FW
Biology of reproduction 2022 May 17;106(5):865-878
Biology of reproduction 2022 May 17;106(5):865-878
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Sandusky-Beltran LA, Kovalenko A, Placides DS, Ratnasamy K, Ma C, Hunt JB Jr, Liang H, Calahatian JIT, Michalski C, Fahnestock M, Blair LJ, Darling AL, Baker JD, Fontaine SN, Dickey CA, Gamsby JJ, Nash KR, Abner E, Selenica MB, Lee DC
The Journal of clinical investigation 2021 Feb 15;131(4)
The Journal of clinical investigation 2021 Feb 15;131(4)
Regulation of Spermine Oxidase through Hypoxia-Inducible Factor-1α Signaling in Retinal Glial Cells under Hypoxic Conditions.
Wu D, Noda K, Murata M, Liu Y, Kanda A, Ishida S
Investigative ophthalmology & visual science 2020 Jun 3;61(6):52
Investigative ophthalmology & visual science 2020 Jun 3;61(6):52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PAOX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PAOX. This antibody recognizes human, mouse, rat antigen. The PAOX antibody has been validated for the following applications: ELISA, WB analysis.
