Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 14367-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14367-1-AP, RRID:AB_2107667
- Product name
- GAA antibody
- Antibody type
- Polyclonal
- Description
- GAA antibody (Cat. #14367-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.
Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.
Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease.
Disruption of the gaa Gene in Zebrafish Fails to Generate the Phenotype of Classical Pompe Disease.
Li X, Yu X, Yu F, Fu C, Zhao W, Liu X, Dai C, Gao H, Cheng M, Li B
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.
Conroy LR, Clarke HA, Allison DB, Valenca SS, Sun Q, Hawkinson TR, Young LEA, Ferreira JE, Hammonds AV, Dunne JB, McDonald RJ, Absher KJ, Dong BE, Bruntz RC, Markussen KH, Juras JA, Alilain WJ, Liu J, Gentry MS, Angel PM, Waters CM, Sun RC
Nature communications 2023 May 13;14(1):2759
Nature communications 2023 May 13;14(1):2759
Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.
Kato A, Nakagome I, Kise M, Yoshimura K, Tanaka N, Nash RJ, Fleet GWJ, Kobayashi Y, Ikeda H, Okada T, Toyooka N
Journal of medicinal chemistry 2023 Jul 13;66(13):9023-9039
Journal of medicinal chemistry 2023 Jul 13;66(13):9023-9039
Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.
Kato A, Nakagome I, Yoshimura K, Kanekiyo U, Kishida M, Shinzawa K, Lu TT, Li YX, Nash RJ, Fleet GWJ, Tanaka N, Yu CY
Organic & biomolecular chemistry 2022 Sep 21;20(36):7250-7260
Organic & biomolecular chemistry 2022 Sep 21;20(36):7250-7260
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease.
Kato A, Nakagome I, Kanekiyo U, Lu TT, Li YX, Yoshimura K, Kishida M, Shinzawa K, Yoshida T, Tanaka N, Jia YM, Nash RJ, Fleet GWJ, Yu CY
Journal of medicinal chemistry 2022 Feb 10;65(3):2329-2341
Journal of medicinal chemistry 2022 Feb 10;65(3):2329-2341
Disruption of the gaa Gene in Zebrafish Fails to Generate the Phenotype of Classical Pompe Disease.
Wu J, Yang Y, Sun C, Sun S, Li Q, Yao Y, Fei F, Lu L, Chang Z, Zhang W, Wang X, Luo F
DNA and cell biology 2017 Jan;36(1):10-17
DNA and cell biology 2017 Jan;36(1):10-17
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 14367-1-AP(GAA antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 14367-1-AP(GAA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAA. This antibody recognizes human, mouse, rat antigen. The GAA antibody has been validated for the following applications: ELISA, WB, IHC analysis.