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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 14367-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14367-1-AP, RRID:AB_2107667
- Product name
- GAA antibody
- Antibody type
- Polyclonal
- Description
- GAA antibody (Cat. #14367-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
GAA replacement improves respiratory muscle, neural, and alveolar pathology in the pompe mouse.
Glycophagy is involved in cardiac glycogen regulation in response to exercise.
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.
Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.
Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.
Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease.
Disruption of the gaa Gene in Zebrafish Fails to Generate the Phenotype of Classical Pompe Disease.
Wang H, Xiao T, Zhuang H, Liu Y, Jin K, Li J, Li J, Gao Y, Yue D, Cui W, Xu Q, Pan J, Liu K, Wang Y, Chen R, Li H
Cell reports 2025 Oct 28;44(10):116429
Cell reports 2025 Oct 28;44(10):116429
GAA replacement improves respiratory muscle, neural, and alveolar pathology in the pompe mouse.
Roger AL, El Haddad L, Huston ML, Kehoe S, Le D, Khan M, Scarrow E, Gonzalez T, Benkert A, Asokan A, ElMallah MK
Respiratory physiology & neurobiology 2025 Jul;335:104433
Respiratory physiology & neurobiology 2025 Jul;335:104433
Glycophagy is involved in cardiac glycogen regulation in response to exercise.
James SL, Koutsifeli P, D'Souza RF, Masson SW, Woodhead JS, Merry TL, Delbridge LM, Mellor KM
Current research in physiology 2024;7:100131
Current research in physiology 2024;7:100131
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Li X, Yu X, Yu F, Fu C, Zhao W, Liu X, Dai C, Gao H, Cheng M, Li B
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.
Guo H, Li Y, Wang S, Yang Y, Xu T, Zhao J, Wang J, Zuo W, Wang P, Zhao G, Wang H, Hou W, Dong H, Cai Y
Redox biology 2024 Aug;74:103234
Redox biology 2024 Aug;74:103234
Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.
Conroy LR, Clarke HA, Allison DB, Valenca SS, Sun Q, Hawkinson TR, Young LEA, Ferreira JE, Hammonds AV, Dunne JB, McDonald RJ, Absher KJ, Dong BE, Bruntz RC, Markussen KH, Juras JA, Alilain WJ, Liu J, Gentry MS, Angel PM, Waters CM, Sun RC
Nature communications 2023 May 13;14(1):2759
Nature communications 2023 May 13;14(1):2759
Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.
Kato A, Nakagome I, Kise M, Yoshimura K, Tanaka N, Nash RJ, Fleet GWJ, Kobayashi Y, Ikeda H, Okada T, Toyooka N
Journal of medicinal chemistry 2023 Jul 13;66(13):9023-9039
Journal of medicinal chemistry 2023 Jul 13;66(13):9023-9039
Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.
Kato A, Nakagome I, Yoshimura K, Kanekiyo U, Kishida M, Shinzawa K, Lu TT, Li YX, Nash RJ, Fleet GWJ, Tanaka N, Yu CY
Organic & biomolecular chemistry 2022 Sep 21;20(36):7250-7260
Organic & biomolecular chemistry 2022 Sep 21;20(36):7250-7260
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease.
Kato A, Nakagome I, Kanekiyo U, Lu TT, Li YX, Yoshimura K, Kishida M, Shinzawa K, Yoshida T, Tanaka N, Jia YM, Nash RJ, Fleet GWJ, Yu CY
Journal of medicinal chemistry 2022 Feb 10;65(3):2329-2341
Journal of medicinal chemistry 2022 Feb 10;65(3):2329-2341
Disruption of the gaa Gene in Zebrafish Fails to Generate the Phenotype of Classical Pompe Disease.
Wu J, Yang Y, Sun C, Sun S, Li Q, Yao Y, Fei F, Lu L, Chang Z, Zhang W, Wang X, Luo F
DNA and cell biology 2017 Jan;36(1):10-17
DNA and cell biology 2017 Jan;36(1):10-17
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 14367-1-AP(GAA antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 14367-1-AP(GAA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAA. This antibody recognizes human, mouse, rat antigen. The GAA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
