Tissue expression
Cell line expression
Protein structure
B4GALT4
Beta-1,4-galactosyltransferase 4beta4Gal-T4
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN394495 | 5 references | Monoclonal |
WB
EL
IHC
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Novus Biologicals | H00008702-M01 | Monoclonal |
WB
EL
BN
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Proteintech Group | 15200-1-AP | Polyclonal |
WB
EL
IHC
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NovoPro Bioscience Inc. | 108395 | Polyclonal |
WB
EL
IHC
|
||
Invitrogen Antibodies | 15200-1-AP | Polyclonal |
WB
IHC |
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