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- Product number
- NBP2-33867 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal TSPAN1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human TSPAN1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Tetraspanin 1 as a mediator of fibrosis inhibits EMT process and Smad2/3 and beta-catenin pathway in human pulmonary fibrosis.
TSPAN1 upregulates MMP2 to promote pancreatic cancer cell migration and invasion via PLCĪ³.
Silencing Tspan1 inhibits migration and invasion, and induces the apoptosis of human pancreatic cancer cells.
miR-491-3p suppresses the growth and invasion of osteosarcoma cells by targeting TSPAN1.
Liu G, Wang Y, Yang L, Zou B, Gao S, Song Z, Lin Z
Journal of cellular and molecular medicine 2019 May;23(5):3583-3596
Journal of cellular and molecular medicine 2019 May;23(5):3583-3596
TSPAN1 upregulates MMP2 to promote pancreatic cancer cell migration and invasion via PLCĪ³.
Zhang X, Shi G, Gao F, Liu P, Wang H, Tan X
Oncology reports 2019 Apr;41(4):2117-2125
Oncology reports 2019 Apr;41(4):2117-2125
Silencing Tspan1 inhibits migration and invasion, and induces the apoptosis of human pancreatic cancer cells.
Tian J, Zhang R, Piao H, Li X, Sheng W, Zhou J, Dong M, Zhang X, Yan X, Shang W, Zhao J, Xu L, Liu F, Shi G
Molecular medicine reports 2018 Sep;18(3):3280-3288
Molecular medicine reports 2018 Sep;18(3):3280-3288
miR-491-3p suppresses the growth and invasion of osteosarcoma cells by targeting TSPAN1.
Duan J, Liu J, Liu Y, Huang B, Rao L
Molecular medicine reports 2017 Oct;16(4):5568-5574
Molecular medicine reports 2017 Oct;16(4):5568-5574
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TSPAN1 Antibody [NBP2-33867] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TSPAN1 Antibody [NBP2-33867] - Analysis in human cell line PC-3 and human cell line HeLa.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSPAN1 Antibody [NBP2-33867] - Analysis in human kidney and skeletal muscle tissues. Corresponding RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSPAN1 Antibody [NBP2-33867] - Staining of human colon shows weak to moderate cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSPAN1 Antibody [NBP2-33867] - Staining of human prostate shows moderate to strong cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSPAN1 Antibody [NBP2-33867] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TSPAN1 Antibody [NBP2-33867] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in tubules.
