PRKCG

gene product
MGC57564, PKC?, PKCC, PKCG, SCA14
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
antibodies-online
212 antibodies
Novus Biologicals
9 antibodies
Aviva Systems Biology
7 antibodies
Abnova Corporation
5 antibodies
Boster Biological Technology
2 antibodies
Invitrogen Antibodies
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GeneTex
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OriGene
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Acris Antibodies GmbH
5 antibodies
NSJ Bioreagents
2 antibodies
Abgent
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Enzo Life Sciences
2 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
Affinity Biosciences
3 antibodies
RabMAbs
5 antibodies
Creative Diagnostics
7 antibodies
Creative Biolabs
11 antibodies
MyBioSource
13 antibodies
Atlas Antibodies
2 antibodies
ProSci
3 antibodies
R&D Systems
1 antibody
St John's Laboratory
4 antibodies
Bioworld Technology, Inc
1 antibody
DB Biotech
1 antibody
United States Biological
39 antibodies
RayBiotech, Inc.
1 antibody
Abbexa
3 antibodies
EMD Millipore
3 antibodies
Sigma-Aldrich
3 antibodies