Tissue expression
Cell line expression

PRKCG

gene product
MGC57564, PKCC, PKCG, PKCĪ³, SCA14 
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
751 antibodies from 39 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
4 antibodies
Invitrogen Antibodies
31 antibodies
Biorbyt
130 antibodies
Wuhan Fine Biotech Co., Ltd.
3 antibodies
NovoPro Bioscience Inc.
3 antibodies
antibodies-online
212 antibodies
Aviva Systems Biology
7 antibodies
Novus Biologicals
9 antibodies
Abnova Corporation
5 antibodies
GeneTex
8 antibodies
LifeSpan BioSciences, Inc.
122 antibodies
St John's Laboratory
6 antibodies
Cell Signaling Technology, Inc
6 antibodies
OriGene
7 antibodies
Acris Antibodies GmbH
5 antibodies
NSJ Bioreagents
2 antibodies
Abgent
2 antibodies
Enzo Life Sciences
2 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
Boster Biological Technology
2 antibodies
Cusabio Biotech Co., Ltd
11 antibodies
Affinity Biosciences
3 antibodies
RabMAbs
5 antibodies
Creative Diagnostics
7 antibodies
HUABIO Research
1 antibody
MyBioSource
13 antibodies
Atlas Antibodies
2 antibodies
ProSci
3 antibodies
R&D Systems
1 antibody
Creative Biolabs
12 antibodies
Abbexa
27 antibodies
Bioworld Technology, Inc
1 antibody
DB Biotech
1 antibody
United States Biological
39 antibodies
Leading Biology
2 antibodies
RayBiotech, Inc.
1 antibody
EMD Millipore
3 antibodies
MilliporeSigma / Merck KGaA
4 antibodies