CACNG8

The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon. [provided by RefSeq, Dec 2010]

Description

Calcium voltage-gated channel auxiliary subunit gamma 8

Tissue specificity

Tissue enriched (brain)

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)
Transporters

Chromosome

19 (53962937 - 53990215)

Ensembl ID

ENSG00000142408  (ver. 103.38)

Orthologs

Mouse Cacng8: ENSMUSG00000053395

UniProt

Q8WXS5

neXtProt

NX_Q8WXS5

Human splice variants
Mouse splice variants

Protein structure