orb147623

antibody from Biorbyt
Targeting: SOD3 EC-SOD
Provider product page for orb147623
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb147623 - Provider product page
Provider
Biorbyt
Product name
SOD (EC) Antibody: PerCP
Antibody type
Monoclonal
Description
Mouse monoclonal to SOD (PerCP). Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms. There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity..
Reactivity
Human, Mouse, Rat, Guinea Pig
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Antibody clone number
4GG11G6
Vial size
100 ug
Concentration
1 mg/ml
Storage
Conjugated antibodies should be stored according to the product label
SOD3 protein structure - orb147623 shown in red.