Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8235 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TFPT polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human TFPT.
- Description
- TFPT (TCF3 fusion partner), also known as INO80F or protein FB1, is a 253 amino acid nuclear protein. TFPT is a component of the chromatin-remoldeling INO80 complex, which is composed of proteins such as BAF53, ACTR5, ACTR8, INOC1, INO80B, INO80C, INO80D and INO80E. The INO80 complex, in addition to chromatin-remoldeling, plays a role in DNA repair, DNA replication, checkpoint regulation, telomere maintenance and chromosome segregation. TFPT interacts with ARC and appears to promote apoptosis in a TP53/p53-independent manner. It is also thought that a chromosomal aberration involving the genes that encode TFPT and E2A is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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