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Western blot
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- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 19563-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19563-1-AP, RRID:AB_10643379
- Product name
- UBASH3B/STS 1 antibody
- Antibody type
- Polyclonal
- Description
- UBASH3B/STS 1 antibody (Cat. #19563-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression.
Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins.
PSGL-1 attenuates early TCR signaling to suppress CD8(+) T cell progenitor differentiation and elicit terminal CD8(+) T cell exhaustion.
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses.
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Prazosin inhibits the growth and mobility of osteosarcoma cells.
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.
Inhibition of T cell activation and function by the adaptor protein CIN85.
Wang J, Wang C, Hu A, Yu K, Kuang Y, Gajendran B, Zacksenhaus E, Sample KM, Xiao X, Liu W, Ben-David Y
BMC cancer 2024 Mar 9;24(1):326
BMC cancer 2024 Mar 9;24(1):326
Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins.
Aziz F, Reddy K, Fernandez Vega V, Dey R, Hicks KA, Rao S, Jordan LO, Smith E, Shumate J, Scampavia L, Carpino N, Spicer TP, French JB
Journal of medicinal chemistry 2024 Feb 8;67(3):1949-1960
Journal of medicinal chemistry 2024 Feb 8;67(3):1949-1960
PSGL-1 attenuates early TCR signaling to suppress CD8(+) T cell progenitor differentiation and elicit terminal CD8(+) T cell exhaustion.
Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM
Cell reports 2023 May 30;42(5):112436
Cell reports 2023 May 30;42(5):112436
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
Li N, Wang Y, Wang A, Zhang J, Jia C, Yu C, Song Z, Wang S, Liu L, Yi J, Bao Y, Huang Y, Sun L
International journal of molecular sciences 2023 Feb 3;24(3)
International journal of molecular sciences 2023 Feb 3;24(3)
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses.
Monticone G, Huang Z, Csibi F, Leit S, Ciccone D, Champhekar AS, Austin JE, Ucar DA, Hossain F, Ibba SV, Boulares AH, Carpino N, Xu K, Majumder S, Osborne BA, Loh C, Miele L
Frontiers in immunology 2022;13:987298
Frontiers in immunology 2022;13:987298
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Yao Y, Liu W, Gajendran B, Wang C, Zacksenhaus E, Sample KM, Varier KM, Hao X, Ben-David Y
Biochimie 2021 May;184:8-17
Biochimie 2021 May;184:8-17
Prazosin inhibits the growth and mobility of osteosarcoma cells.
An M, Ma WH, Jia HW, Li YW, Feng JJ, Meng J, Qi H, Liu J
Translational cancer research 2019 Sep;8(5):1997-2004
Translational cancer research 2019 Sep;8(5):1997-2004
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.
Lundby A, Franciosa G, Emdal KB, Refsgaard JC, Gnosa SP, Bekker-Jensen DB, Secher A, Maurya SR, Paul I, Mendez BL, Kelstrup CD, Francavilla C, Kveiborg M, Montoya G, Jensen LJ, Olsen JV
Cell 2019 Oct 3;179(2):543-560.e26
Cell 2019 Oct 3;179(2):543-560.e26
Inhibition of T cell activation and function by the adaptor protein CIN85.
Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T
Science signaling 2019 Feb 5;12(567)
Science signaling 2019 Feb 5;12(567)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 19563-1-AP(UBASH3B antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-UBASH3B (IP:19563-1-AP, 3ug; Detection:19563-1-AP 1:300) with mouse kidney tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 19563-1-AP(UBASH3B antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UBASH3B/STS 1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human UBASH3B/STS 1. This antibody recognizes human,mouse,rat antigen. The UBASH3B/STS 1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
