66475-1-Ig

antibody from Proteintech Group

Targeting: TXN TRX

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66475-1-Ig

Provider

Proteintech Group

Product name

Thioredoxin antibody

Antibody type

Monoclonal

Description

Thioredoxin antibody (Cat. #66475-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1F3C1

Vial size

20ul, 150ul

References

Submitted references

PK11007 Covalently Inhibits Thioredoxin Reductase 1 to Induce Oxidative Stress and Autophagy Impairment in NSCLC Cells.

Zhou H, Sun S, Liu H, Li T, Xu Y, Yang R, Liu H, He L, Xu W, Guan S, Xu J
Antioxidants (Basel, Switzerland) 2025 Oct 11;14(10)

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Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics.

Zheng X, Mund A, Mann M
Molecular cell 2025 Mar 6;85(5):1008-1023.e7

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Pharmacological Inhibition of TXNRD1 by a Small Molecule Flavonoid Butein Overcomes Cisplatin Resistance in Lung Cancer Cells.

Yang R, Sun S, Zhang Q, Liu H, Wang L, Meng Y, Chen N, Wang Z, Liu H, Ji F, Dai Y, He G, Xu W, Ye Z, Zhang J, Ma Q, Xu J
Biological trace element research 2025 Apr;203(4):1949-1960

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Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif.

Shi W, Sun S, Liu H, Meng Y, Ren K, Wang G, Liu M, Wu J, Zhang Y, Huang H, Shi M, Xu W, Ma Q, Sun B, Xu J
Redox biology 2024 Apr;70:103050