Antibody data
- Antibody Data
- Antigen structure
- References [68]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14555-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14555-1-AP, RRID:AB_2212258
- Product name
- alpha Tubulin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Tubulin antibody (Cat. #14555-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references MYC-Mediated Functional Manifestation of IDH1 Mutations in Intrahepatic Cholangiocarcinoma Confers Sensitivity to (+)-JQ1.
3-Hydroxystearic acid promotes cholesterol efflux and attenuates atherosclerosis via the ALKBH5/PAX-8/ABCA1 pathway.
cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells.
Deficiency of primate-specific TFDP3 causes male infertility with oligoasthenoteratozoospermia in humans and cynomolgus monkeys.
Inhibition of PRMT5 triggers synthetic lethality in ARID1A-deficient endometrial cancer by promoting aberrant R-loop accumulation.
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.
Structural and evolutionary insights into the eukaryotic RNase MRP ribonucleoprotein complex.
Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells.
CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma.
Kaiyujiangzhuo formula alleviates glycolipid metabolic disorders by improving arginine metabolism and inhibiting the ERK-mediated PPARγ-Ser273 phosphorylation.
Exploring the Active Substances and Mechanism of Physalis Calyx seu Fructus Against Inflammation-related Respiratory Diseases via Integrating Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry, Network Pharmacological Analysis, and Experimental Verification.
Single-Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage.
AVIL promotes osteosarcoma progression and cisplatin resistance via ARP2/3-mediated DNA damage repair.
KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression.
Mitochondrial DNA drives NLRP3-IL-1β axis activation in microglia by binding to NLRP3, leading to neurodegeneration in Parkinson's disease models.
ANKFY1 suppresses PDCoV replication by degrading viral nsp8 protein via p62-dependent selective autophagy.
Characterizations of G-Quadruplex RNA-Protein Interactions in Living Cells.
Oroxin A in Linggui Zhugan Decoction in the treatment of MASH by regulating cholesterol-bile acid metabolism.
CAR-M2 immunotherapy resolves renal fibrosis via revascularization and apoptosis of profibrotic Cxcr2(+) endothelial cells.
Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation.
SOX9 mediates the phenotypic transformation of vascular smooth muscle cells in restenosis after carotid artery injury.
The endogenous glutamatergic transmitter system promotes collagen synthesis in cardiac fibroblasts under hypoxia.
Nutrients regulation of skin cells from canines and cats via Wnt/β-catenin signaling pathway.
Ameliorative effects of Gly[14]-humanin on cyclophosphamide-induced premature ovarian insufficiency and underlying mechanisms.
Baicalein suppresses the malignant progression of acute myeloid leukemia via ROS-dependent metabolic reprogramming: Mechanisms of differentiation induction and ferroptosis activation.
Acute REM sleep deprivation alleviated depression-like behavior mediated by inhibiting VIP neurons in the mPFC.
11β-HSD1 inhibitor alleviates sepsis-induced cardiac dysfunction by regulating macrophage polarization via the AMPK/mTOR autophagy pathway.
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing.
M2 Macrophage-Derived Migrasomes Mediate Ischaemia-Induced Retinal Neovascularization by Targeting TREM2.
SIRT3 deficiency aggravates mitochondrial metabolic disorder and podocyte injury in DKD via MPC2 acetylation.
Perinuclear theca protein FNDC8 interacts with CCIN and ACTL7A to ensure proper sperm head shaping during spermiogenesis.
Oleracein E Rejuvenates Senescent Hippocampal NSCs by Inhibiting the ERK1/2-mTOR Axis to Improve Cognitive Dysfunction in Vascular Dementia.
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Integrated proteomics and metabolomics to clarify the essential beneficial mechanisms of L-theanine in alleviating ISO-induced cardiac damage in mice.
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF-κB Nuclear Translocation Signaling in Chronic Migraine Male Rats.
Astaxanthin ameliorates benzalkonium chloride-induced dry eye disease through suppressing inflammation and oxidative stress via Keap1-Nrf2/HO-1 signaling pathways.
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
An intronic variant in LAMB3 contributes to junctional epidermolysis bullosa and enamel hypoplasia via translational attenuation.
Supervillin-Mediated ZO-1 Downregulation Facilitates Migration of Cisplatin-Resistant HCT116 Colorectal Cancer Cells.
hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p.
MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway.
Integration of vitro models with machine learning and epidemiological data reveals PCB-induced glucose metabolism disruption linked to mitochondrial dysfunction.
Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer.
[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].
Plasma-Derived Exosomal i-tRF-LeuCAA as Biomarker for Glioma Diagnosis and Promoter of Epithelial-Mesenchymal Transition via TPM4 Regulation.
Chronic stress enhances neuropathic pain through activation of the anterior cingulate cortex-spinal dorsal horn pathway in rats.
The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastoma.
Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis.
Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.
Identification of a novel caspase cleavage motif AEAD.
Rift Valley fever virus coordinates the assembly of a programmable E3 ligase to promote viral replication.
Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD.
NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells.
The effect of m6A methyltransferase METTL3 mediated TMEM30A regulation on tumor energy metabolism and cisplatin anti-tumor activity in oral squamous cell carcinoma.
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level.
Regulation of the WNT-CTNNB1 signaling pathway by severe fever with thrombocytopenia syndrome virus in a cap-snatching manner.
Injectable selenium-containing polymeric hydrogel formulation for effective treatment of myocardial infarction.
Arf-like Protein 2 (ARL2) Controls Microtubule Neogenesis during Early Postnatal Photoreceptor Development.
Tau nuclear translocation is a leading step in tau pathology process through P53 stabilization and nucleolar dispersion.
Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E.
SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation.
Chemosensitization and mitigation of Adriamycin-induced cardiotoxicity using combinational polymeric micelles for co-delivery of quercetin/resveratrol and resveratrol/curcumin in ovarian cancer.
ARF6 protects sister chromatid cohesion to ensure the formation of stable kinetochore-microtubule attachments.
Identification and characterization of INMAP, a novel interphase nucleus and mitotic apparatus protein that is involved in spindle formation and cell cycle progression.
Wang F, Liu X, Zhang N, Kong R
International journal of biological sciences 2026;22(5):2247-2264
International journal of biological sciences 2026;22(5):2247-2264
3-Hydroxystearic acid promotes cholesterol efflux and attenuates atherosclerosis via the ALKBH5/PAX-8/ABCA1 pathway.
Zhou QY, Liu W, Zhao ZW, Gong D, Ma XF, Tang CK
Frontiers in immunology 2026;17:1750021
Frontiers in immunology 2026;17:1750021
cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells.
Ouyang Y, Qin Y, Zhang Q, Zhu P, Zhu H
Frontiers in oncology 2026;16:1764427
Frontiers in oncology 2026;16:1764427
Deficiency of primate-specific TFDP3 causes male infertility with oligoasthenoteratozoospermia in humans and cynomolgus monkeys.
Liu C, Tu C, Li P, Wu H, Wan F, Lu Y, Tang S, Li X, Li K, Wang J, Gao Y, Geng X, Meng L, Zhou D, Zhou Y, Zhou Z, Guo H, Cao Y, Jin L, Li Z, He X, Tan YQ, Sun Q, Zhang F
Science China. Life sciences 2026 May;69(5):1594-1603
Science China. Life sciences 2026 May;69(5):1594-1603
Inhibition of PRMT5 triggers synthetic lethality in ARID1A-deficient endometrial cancer by promoting aberrant R-loop accumulation.
Shu W, Dong K, Shen X, Zhou X, Zhang J, Yu S, Cheng S, Zhang T, Chen G, Zhong G, Zhang J, Wang H
Molecular cancer 2026 Mar 9;25(1)
Molecular cancer 2026 Mar 9;25(1)
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.
Zhang Z, Liu J, Liu Y, Wang L, Li Z, Dong Y, Tian Y, Miao X, Liu Q, Zhang W, Guo H, Xing L, Yang L, Feng X, Liu S
Cells 2026 Mar 4;15(5)
Cells 2026 Mar 4;15(5)
Structural and evolutionary insights into the eukaryotic RNase MRP ribonucleoprotein complex.
Zhou B, Wang X, Wan F, Li S, Zhang X, Zhang Y, Tan M, Cao M, Shen Y, Gao R, Zhang Y, Lan P, Wu J, Lei M
Nature communications 2026 Mar 26;17(1)
Nature communications 2026 Mar 26;17(1)
Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells.
Zhang Q, Wang Y, Fu X, Wang Z, Zhang Y, Yan L, Wang Y, Yang M, Song D, Zhang R, Zhang H, Wu S, Zhao S
eLife 2026 Mar 25;14
eLife 2026 Mar 25;14
CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma.
Cao Y, Xu C, Liu Y, Shi B, Li X, Li J, Zhang B, Zhang Z, Dai S, Sun Q, Gu J
iScience 2026 Mar 20;29(3):114840
iScience 2026 Mar 20;29(3):114840
Kaiyujiangzhuo formula alleviates glycolipid metabolic disorders by improving arginine metabolism and inhibiting the ERK-mediated PPARγ-Ser273 phosphorylation.
Shi Y, Zhang Z, Lin H, Wang S, Wang D, Wu H, Qi H, Wang Y, Liu Q, Zhang Y, Xiong H, Ren J, Li X, Wang Z
Journal of ethnopharmacology 2026 Jun 12;364:121508
Journal of ethnopharmacology 2026 Jun 12;364:121508
Exploring the Active Substances and Mechanism of Physalis Calyx seu Fructus Against Inflammation-related Respiratory Diseases via Integrating Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry, Network Pharmacological Analysis, and Experimental Verification.
Meng H, Xu LT, Li PP, Guo DX, Li GH, Gu HR, Wang XN, Lin YQ, Xu ZP, Shen T
Chemistry & biodiversity 2026 Jan;23(1):e00496
Chemistry & biodiversity 2026 Jan;23(1):e00496
Single-Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage.
Xie L, Cai Y, Chen B, Li B, Zou J, Xu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e00438
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e00438
AVIL promotes osteosarcoma progression and cisplatin resistance via ARP2/3-mediated DNA damage repair.
Chen Z, Tang G, Lv X, Ding G, Huang M, Chen Z, Dai S, Liu H, Zhang S, Cai L
Translational oncology 2026 Feb;64:102654
Translational oncology 2026 Feb;64:102654
KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression.
Huang X, Meng Y, Song J, Zhu Y, Li J, Xi Y, Peng X, Xiong Y
iScience 2026 Feb 20;29(2):114734
iScience 2026 Feb 20;29(2):114734
Mitochondrial DNA drives NLRP3-IL-1β axis activation in microglia by binding to NLRP3, leading to neurodegeneration in Parkinson's disease models.
Gan Q, Fu X, Zhou T, Fan N, Nan N, Wang Y, Yang Y, Gou S, Hu L, Zhou S
Cell death & disease 2026 Feb 10;17(1):213
Cell death & disease 2026 Feb 10;17(1):213
ANKFY1 suppresses PDCoV replication by degrading viral nsp8 protein via p62-dependent selective autophagy.
Xu Y, Zhang Y, Zhu H, Yu X, Lou J, Liu M, Liu G, Bai J, Jiang P, Yang Z, Wang X
Veterinary microbiology 2026 Apr;315:110927
Veterinary microbiology 2026 Apr;315:110927
Characterizations of G-Quadruplex RNA-Protein Interactions in Living Cells.
Tang F, Liang X, Porter DF, Miao W, Maehlmann K, Yuan J, Khavari PA, Wang Y
Analytical chemistry 2026 Apr 28;98(16):12090-12098
Analytical chemistry 2026 Apr 28;98(16):12090-12098
Oroxin A in Linggui Zhugan Decoction in the treatment of MASH by regulating cholesterol-bile acid metabolism.
Gao P, Wang S, Jia M, Meng J, Jia B, Chen Y, Xing Q, Wang W, Zhang Y, Chai X
Journal of ethnopharmacology 2026 Apr 28;368:121684
Journal of ethnopharmacology 2026 Apr 28;368:121684
CAR-M2 immunotherapy resolves renal fibrosis via revascularization and apoptosis of profibrotic Cxcr2(+) endothelial cells.
Zhao W, Zhou X, Zhao X, Tian H, Su Y, Zhao S, Liu M, Zhang Q, Chen L, Li X, Liu D, Li J, Li L, Wang Y, Li X, Yan J, Chen W, Liu B, Zhu C, Zeng W
Cell reports. Medicine 2026 Apr 21;7(4):102698
Cell reports. Medicine 2026 Apr 21;7(4):102698
Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation.
Yu J, Kang X, Chang R, Zhang C, Yang S, Chen L, Wang X, Hu B, Wang Z, Gong L, Liu L
Frontiers in pharmacology 2025;16:1704023
Frontiers in pharmacology 2025;16:1704023
SOX9 mediates the phenotypic transformation of vascular smooth muscle cells in restenosis after carotid artery injury.
Jiang C, Ye J, Huang J, Gao Y, Chen H, Guo F, Guo L, Yuan X
Frontiers in cell and developmental biology 2025;13:1592594
Frontiers in cell and developmental biology 2025;13:1592594
The endogenous glutamatergic transmitter system promotes collagen synthesis in cardiac fibroblasts under hypoxia.
Wang R, Yuan X, Xie T, Zhao X, Li J, Zhang X, Lv C
Frontiers in cardiovascular medicine 2025;12:1638650
Frontiers in cardiovascular medicine 2025;12:1638650
Nutrients regulation of skin cells from canines and cats via Wnt/β-catenin signaling pathway.
Sun X, Ma Y, Gao Y, Li J, Li Y, Lv L
Frontiers in veterinary science 2025;12:1486201
Frontiers in veterinary science 2025;12:1486201
Ameliorative effects of Gly[14]-humanin on cyclophosphamide-induced premature ovarian insufficiency and underlying mechanisms.
Huang J, Liu Y, Zou L, Zhu C, Xia W
Reproductive biomedicine online 2025 Sep;51(3):104901
Reproductive biomedicine online 2025 Sep;51(3):104901
Baicalein suppresses the malignant progression of acute myeloid leukemia via ROS-dependent metabolic reprogramming: Mechanisms of differentiation induction and ferroptosis activation.
Wang M, Wang Y, Chen L, Yu S, Li X, Huang G, Jin M
European journal of pharmacology 2025 Sep 5;1002:177839
European journal of pharmacology 2025 Sep 5;1002:177839
Acute REM sleep deprivation alleviated depression-like behavior mediated by inhibiting VIP neurons in the mPFC.
Zhu Y, Wu T, Jiao Q, Chai H, Wang Y, Tian C, Xue Q, Li K, Wang P, Li Z, He H, Chen B, Liu A, Shen H
Science advances 2025 Sep 12;11(37):eadx2666
Science advances 2025 Sep 12;11(37):eadx2666
11β-HSD1 inhibitor alleviates sepsis-induced cardiac dysfunction by regulating macrophage polarization via the AMPK/mTOR autophagy pathway.
Zhang Z, Yin B, Zhu D, Wu D, Huang M, Zhou S
Journal of cardiology 2025 Sep 10;
Journal of cardiology 2025 Sep 10;
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Chen S, Chen T, Xu C, Yu X, Shi J, Yang C, Zhu T
Redox biology 2025 Oct;86:103795
Redox biology 2025 Oct;86:103795
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing.
Su Y, Lu J, Liang F, Cheng J
Biomolecules 2025 Oct 24;15(11)
Biomolecules 2025 Oct 24;15(11)
M2 Macrophage-Derived Migrasomes Mediate Ischaemia-Induced Retinal Neovascularization by Targeting TREM2.
Li B, Chen J, Zhu J, Zhou H, Zhang Q, Deng H, Wen H, Xu F, Tang F, Yoshida S, Zhou Y
Journal of extracellular vesicles 2025 Nov;14(11):e70180
Journal of extracellular vesicles 2025 Nov;14(11):e70180
SIRT3 deficiency aggravates mitochondrial metabolic disorder and podocyte injury in DKD via MPC2 acetylation.
Feng J, Feng L, Yan Y, Ye H, Tang K, Guo X, Ma Y
Cellular signalling 2025 Nov;135:112029
Cellular signalling 2025 Nov;135:112029
Perinuclear theca protein FNDC8 interacts with CCIN and ACTL7A to ensure proper sperm head shaping during spermiogenesis.
Liu JY, Long CH, Wang LY, Ma YJ, Zheng YL, Li W, Wu BB, Wu HB
Zoological research 2025 Nov 18;46(6):1259-1272
Zoological research 2025 Nov 18;46(6):1259-1272
Oleracein E Rejuvenates Senescent Hippocampal NSCs by Inhibiting the ERK1/2-mTOR Axis to Improve Cognitive Dysfunction in Vascular Dementia.
Lang H, Zeng J, Wen Y, Xu J, Xiao R, Shi Y, Lu Q, Xia X, Hu G
The European journal of neuroscience 2025 May;61(9):e70137
The European journal of neuroscience 2025 May;61(9):e70137
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Cai Y, Xu H, Deng K, Yang H, Zhao B, Zhang C, Li S, Wei Z, Wang Z, Wang F, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 1):141271
International journal of biological macromolecules 2025 May;306(Pt 1):141271
Integrated proteomics and metabolomics to clarify the essential beneficial mechanisms of L-theanine in alleviating ISO-induced cardiac damage in mice.
Wang G, Zhang L, Li W, Liu X, Huang J
Food research international (Ottawa, Ont.) 2025 May;209:116235
Food research international (Ottawa, Ont.) 2025 May;209:116235
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Yao X, Wang X, Zhang R, Kong L, Fan C, Qian Y
Nature communications 2025 May 5;16(1):4170
Nature communications 2025 May 5;16(1):4170
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Xu H, Cai Y, Yang H, Zhang C, Liu W, Zhao B, Wang F, Zhang Y
Communications biology 2025 May 29;8(1):824
Communications biology 2025 May 29;8(1):824
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF-κB Nuclear Translocation Signaling in Chronic Migraine Male Rats.
Zhang W, Yang Y, Zhang X, Zhao L, Zhou J, Ji L, Chen L
Phytotherapy research : PTR 2025 Mar;39(3):1438-1452
Phytotherapy research : PTR 2025 Mar;39(3):1438-1452
Astaxanthin ameliorates benzalkonium chloride-induced dry eye disease through suppressing inflammation and oxidative stress via Keap1-Nrf2/HO-1 signaling pathways.
Liu Z, Li Y, Bao J, Li S, Wen Y, Zhang P, Feng J, Wang Y, Tian L, Jie Y
Animal models and experimental medicine 2025 Jun;8(6):1056-1079
Animal models and experimental medicine 2025 Jun;8(6):1056-1079
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Lu Y, Zhang L, Yang B, Hu H, Sun H, Guo D
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
Chen X, Li R, Qiu Y, Lin F, Chen S, Li X, Sun H, Jiang G, Fang H, Qin J, Fang M
Bioorganic chemistry 2025 Jul 15;162:108577
Bioorganic chemistry 2025 Jul 15;162:108577
An intronic variant in LAMB3 contributes to junctional epidermolysis bullosa and enamel hypoplasia via translational attenuation.
Yang Y, Wang Y, Qin M, Zhao Y, Has C, Wang X
Archives of oral biology 2025 Jan;169:106101
Archives of oral biology 2025 Jan;169:106101
Supervillin-Mediated ZO-1 Downregulation Facilitates Migration of Cisplatin-Resistant HCT116 Colorectal Cancer Cells.
Hong Y, Li X, Mao R, Zhou F, Li S, Zhu C, Jin L
Journal of cellular biochemistry 2025 Jan;126(1):e30699
Journal of cellular biochemistry 2025 Jan;126(1):e30699
hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p.
Huang S, Liu K, Xu Y, Wang H, Fu S, Wu J
Scientific reports 2025 Jan 8;15(1):1309
Scientific reports 2025 Jan 8;15(1):1309
MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway.
Xiang Q, Lin H, Tao JS, Fu CJ, Liu LN, Deng J, Li XH
Proteome science 2025 Feb 6;23(1):1
Proteome science 2025 Feb 6;23(1):1
Integration of vitro models with machine learning and epidemiological data reveals PCB-induced glucose metabolism disruption linked to mitochondrial dysfunction.
Li P, Liu Q, Wang Y, Zhang J, Gao C, Yan Y, Zhao Z, Jing T, He M
Toxicology 2025 Dec;518:154264
Toxicology 2025 Dec;518:154264
Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer.
Zhou L, Liu M, Liu F, Wang Z, Li X, Peng X, Ma W, Guo P, Yuan L, Wolczynski S, Rahman NA, Song W, Li X
Oncogene 2025 Dec;44(49):4765-4780
Oncogene 2025 Dec;44(49):4765-4780
[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].
Zhang X, Man J, Zhang Y, Zheng Y, Wang H, Yuan Y, Xie X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681
Plasma-Derived Exosomal i-tRF-LeuCAA as Biomarker for Glioma Diagnosis and Promoter of Epithelial-Mesenchymal Transition via TPM4 Regulation.
Liu H, Hu W, Zhang L, Li Z, Liu J, Chen L
CNS neuroscience & therapeutics 2025 Apr;31(4):e70356
CNS neuroscience & therapeutics 2025 Apr;31(4):e70356
Chronic stress enhances neuropathic pain through activation of the anterior cingulate cortex-spinal dorsal horn pathway in rats.
Yang X, Xu W, Hou X, Ding Z, Zhang C, Guo Q, Zou W, Wang J
Progress in neuro-psychopharmacology & biological psychiatry 2025 Apr 2;138:111352
Progress in neuro-psychopharmacology & biological psychiatry 2025 Apr 2;138:111352
The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastoma.
Gou P, Fang C, Xu M, Zhang D, Wu X, Zhang L, Li X, Li M, Gan L, Luo J, Cui H, Liang P
Cell death discovery 2025 Apr 14;11(1):172
Cell death discovery 2025 Apr 14;11(1):172
Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis.
Pang Q, Huang S, Li X, Cao J
Frontiers in cell and developmental biology 2024;12:1480998
Frontiers in cell and developmental biology 2024;12:1480998
Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.
Chen C, Cao Z, Lei H, Zhang C, Wu M, Huang S, Li X, Xie D, Liu M, Zhang L, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545
Identification of a novel caspase cleavage motif AEAD.
Fang Y, Gong Z, You M, Peng K
Virologica Sinica 2024 Oct;39(5):755-766
Virologica Sinica 2024 Oct;39(5):755-766
Rift Valley fever virus coordinates the assembly of a programmable E3 ligase to promote viral replication.
Li H, Zhang Y, Rao G, Zhang C, Guan Z, Huang Z, Li S, Lozach PY, Cao S, Peng K
Cell 2024 Nov 27;187(24):6896-6913.e15
Cell 2024 Nov 27;187(24):6896-6913.e15
Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD.
Liao Q, Zhang Y, Pan T, Sun Y, Liu S, Zhang Z, Li Y, Yu L, Luo Z, Xiao Y, Qi X, Jiang T, Su S, Liu S, Qi X, Li X, Damba T, Batchuluun K, Liang Y, Wei S, Zhou L
Scientific reports 2024 Nov 15;14(1):28167
Scientific reports 2024 Nov 15;14(1):28167
NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells.
Yang W, Jin M, Wang Y, Zhao H, Wang X, Guo Y, Li C, Xiao B, Zhang H, Kiran F, Wang A, Chao HW, Jin Y, Chen H
International journal of biological macromolecules 2024 Dec;283(Pt 4):137642
International journal of biological macromolecules 2024 Dec;283(Pt 4):137642
The effect of m6A methyltransferase METTL3 mediated TMEM30A regulation on tumor energy metabolism and cisplatin anti-tumor activity in oral squamous cell carcinoma.
Yuan W, Ouyang S, Lv Q, Liao L
Life sciences 2024 Dec 1;358:123122
Life sciences 2024 Dec 1;358:123122
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level.
Wang W, Wang Y, Pei H, Li M, Zhu A, Du R, Peng GJ
Aging 2023 Sep 5;15(18):9426-9437
Aging 2023 Sep 5;15(18):9426-9437
Regulation of the WNT-CTNNB1 signaling pathway by severe fever with thrombocytopenia syndrome virus in a cap-snatching manner.
Jiang X-M, Xin Q-L, Liu K, Peng X-F, Han S, Zhang L-Y, Liu W, Xiao G-F, Li H, Zhang L-K
mBio 2023 Dec 19;14(6):e0168823
mBio 2023 Dec 19;14(6):e0168823
Injectable selenium-containing polymeric hydrogel formulation for effective treatment of myocardial infarction.
Yang C, Zhu C, Li Y, Li Z, Zhang Z, Xu J, Chen M, Li R, Liu S, Wu Y, Huang Z, Wu C
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14555-1-AP(tubulin-Alpha antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The alpha Tubulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha Tubulin. This antibody recognizes human,mouse,rat antigen. The alpha Tubulin antibody has been validated for the following applications: ELISA, IHC, IF, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 14555-1-AP(tubulin-Alpha antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 14555-1-AP(tubulin-Alpha antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue