MBOAT7

This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Description

Membrane bound O-acyltransferase domain containing 7

Tissue specificity

Tissue enhanced (adrenal gland)

Subcell location

Cytosol

Predicted location

Membrane

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Potential drug targets
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

19 (54173412 - 54189882)

Ensembl ID

ENSG00000125505  (ver. 103.38)

Orthologs

Mouse Mboat7: ENSMUSG00000035596

UniProt

Q96N66

neXtProt

NX_Q96N66

Human splice variants
Mouse splice variants

Protein structure