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- Antibody Data
- Antigen structure
- References [290]
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- Product number
- 11554-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11554-1-AP, RRID:AB_2071066
- Product name
- Cyclin E1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Cyclin E1 antibody (Cat. #11554-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Expression and role of FKBPL in lung adenocarcinoma.
Polycomb repressive complex 1 modulates granulosa cell proliferation in early folliculogenesis to support female reproduction.
EXOSC2 Mediates the Pro-tumor Role of WTAP in Breast Cancer Cells via Activating the Wnt/β-Catenin Signal.
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1.
Deciphering the immunological and prognostic features of hepatocellular carcinoma through ADP-ribosylation-related genes analysis and identify potential therapeutic target ARFIP2.
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
RARRES1 identified by comprehensive bioinformatic analysis and experimental validation as a promising biomarker in Skin Cutaneous Melanoma.
Epiberberine induced p53/p21-dependent G2/M cell cycle arrest and cell apoptosis in gastric cancer cells by activating γ-aminobutyric acid receptor- β3.
Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinoma.
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Mitophagy-Mediated Tumor Dormancy Protects Cancer Cells from Chemotherapy.
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Discovery of Novel Antitumor Small-Molecule Agent with Dual Action of CDK2/p-RB and MDM2/p53.
ANP32B inhibition suppresses the growth of prostate cancer cells by regulating c-Myc signaling.
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling.
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs).
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
SHCBP1 Promotes the Proliferation of Breast Cancer Cells by Inhibiting CXCL2.
Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer.
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.
Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway.
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.
Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
In silico protein interaction screening uncovers DONSON's role in replication initiation.
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway.
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.
Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
IL-7 promotes CD19-directed CAR-T cells proliferation through miRNA-98-5p by targeting CDKN1A.
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter.
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma.
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
ASRGL1 downregulation suppresses hepatocellular carcinoma tumorigenesis in a CDK1-dependent manner.
Metformin synergistically enhances the antitumour activity of Lenvatinib in hepatocellular carcinoma by altering AKT-FOXO3 signalling pathway.
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Triptolide inhibits intrahepatic cholangiocarcinoma growth by suppressing glycolysis via the AKT/mTOR pathway.
MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Artesunate and cisplatin synergistically inhibit HNSCC cell growth and promote apoptosis with artesunate‑induced decreases in Rb and phosphorylated Rb levels.
Sanggenon C inhibits cell proliferation and induces apoptosis by regulating the MIB1/DAPK1 axis in glioblastoma.
221S-1a inhibits endothelial proliferation in pathological angiogenesis through ERK/c-Myc signaling.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach.
tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis.
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Effect of miRNA-200b on the proliferation of liver cancer cells via targeting SMYD2/p53 signaling pathway.
Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage.
High expression of HOXA4 in patients with glioma indicates unfavorable clinical outcomes.
Porcine Circovirus 2 Activates the PERK-Reactive Oxygen Species Axis To Induce p53 Phosphorylation with Subsequent Cell Cycle Arrest at S Phase in Favor of Its Replication.
Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Tetracaine hydrochloride induces cell cycle arrest in melanoma by downregulating hnRNPA1.
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2.
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
NUDT21 Promotes Tumor Growth and Metastasis Through Modulating SGPP2 in Human Gastric Cancer.
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Circ_0089823 reinforces malignant behaviors of non-small cell lung cancer by acting as a sponge for microRNAs targeting SOX4().
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma.
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7.
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes.
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Ropivacaine Induces Cell Cycle Arrest in the G0/G1 Phase and Apoptosis of PC12 Cells via Inhibiting Mitochondrial STAT3 Translocation.
Xenobiotic Receptor CAR Is Highly Induced in Psoriasis and Promotes Keratinocyte Proliferation.
S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
PKMYT1, exacerbating the progression of clear cell renal cell carcinoma, is implied as a biomarker for the diagnosis and prognosis.
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells.
Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells.
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
Tissue Inhibitor of Metalloproteinases-2 Mediates Kidney Injury during Sepsis.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
LncRNA IDH1-AS1 suppresses cell proliferation and tumor growth in glioma.
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
SLC25A10 performs an oncogenic role in human osteosarcoma.
Minichromosome maintenance protein 5 is an important pathogenic factor of oral squamous cell carcinoma.
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3.
LINC00963 targeting miR-128-3p promotes acute kidney injury process by activating JAK2/STAT1 pathway.
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancer.
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
HOTAIR-EZH2 inhibitor AC1Q3QWB upregulates CWF19L1 and enhances cell cycle inhibition of CDK4/6 inhibitor palbociclib in glioma.
ASPM promotes glioblastoma growth by regulating G1 restriction point progression and Wnt-β-catenin signaling.
MiR-23a-3p promoted G1/S cell cycle transition by targeting protocadherin17 in hepatocellular carcinoma.
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro.
Mechanism of inhibiting proliferation of hepatocellular carcinoma Hepa1-6 cells by embryonic stem cell-conditioned medium.
Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer.
Activation of CXCL5-CXCR2 axis promotes proliferation and accelerates G1 to S phase transition of papillary thyroid carcinoma cells and activates JNK and p38 pathways.
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
miR-193a/b-3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells.
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses.
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation.
Baicalin inhibits proliferation and promotes apoptosis of vascular smooth muscle cells by regulating the MEG3/p53 pathway following treatment with ox‑LDL.
Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma.
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Upregulation of miR‑95-3p inhibits growth of osteosarcoma by targeting HDGF.
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Motor Neuron and Pancreas Homeobox 1 (MNX1) Is Involved in Promoting Squamous Cervical Cancer Proliferation via Regulating Cyclin E.
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
MicroRNA-107 induces cell cycle arrests by directly targeting cyclin E1 in ovarian cancer.
Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice.
Identification of Grade-associated MicroRNAs in Brainstem Gliomas Based on Microarray Data.
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production.
Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells.
Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2.
VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
HOXA5 is a tumor suppressor gene that is decreased in gastric cancer.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer.
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
IL-2Rα up-regulation is mediated by latent membrane protein 1 and promotes lymphomagenesis and chemotherapy resistance in natural killer/T-cell lymphoma.
Antifibrotic cardioprotection of berberine via downregulating myocardial IGF-1 receptor-regulated MMP-2/MMP-9 expression in diabetic rats.
miR-155 accelerates proliferation of mouse hepatocytes during liver regeneration by directly targeting SOCS1.
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer.
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
ANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1.
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Motor neuron and pancreas homeobox 1/HLXB9 promotes sustained proliferation in bladder cancer by upregulating CCNE1/2.
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway.
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Human Enterovirus 68 Interferes with the Host Cell Cycle to Facilitate Viral Production.
Salusin-β mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Pseudolaric acid B inhibits neuroglioma cell proliferation through DNA damage response.
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
(-)-Curine induces cell cycle arrest and cell death in hepatocellular carcinoma cells in a p53-independent way.
Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGFβ2 feedback loop.
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration.
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
miR-873 suppresses H9C2 cardiomyocyte proliferation by targeting GLI1.
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica.
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Inhibition of tumor suppressor p53 preserves glycation-serum induced pancreatic beta-cell demise.
PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.
Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells.
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
Carfilzomib induces G2/M cell cycle arrest in human endometrial cancer cells via upregulation of p21(Waf1/Cip1) and p27(Kip1).
Paper-based microreactor array for rapid screening of cell signaling cascades.
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition.
Down-regulation of cancer/testis antigen OY-TES-1 attenuates malignant behaviors of hepatocellular carcinoma cells in vitro.
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.
C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis.
Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells.
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.
She L, Zhang X, Shen R, He S, Miao X
Journal of Cancer 2024;15(1):166-175
Journal of Cancer 2024;15(1):166-175
Polycomb repressive complex 1 modulates granulosa cell proliferation in early folliculogenesis to support female reproduction.
Gao M, Zhang T, Chen T, Chen Z, Zhu Z, Wen Y, Qin S, Bao Y, Zhao T, Li H, Liu L, Hao M, Wang J, Wang F, Wang H, Zhou B, Zhang H, Xia G, Wang C
Theranostics 2024;14(4):1371-1389
Theranostics 2024;14(4):1371-1389
EXOSC2 Mediates the Pro-tumor Role of WTAP in Breast Cancer Cells via Activating the Wnt/β-Catenin Signal.
Lv CG, Cheng Y, Zhang L, Wu GG, Liang CY, Tao Z, Chen B
Molecular biotechnology 2024 Sep;66(9):2569-2582
Molecular biotechnology 2024 Sep;66(9):2569-2582
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1.
Zhou M, Gao Y, Wu S, Wang Y, Yang J
Cellular signalling 2024 Sep;121:111265
Cellular signalling 2024 Sep;121:111265
Deciphering the immunological and prognostic features of hepatocellular carcinoma through ADP-ribosylation-related genes analysis and identify potential therapeutic target ARFIP2.
Jiang F, Xu Y, Jiang Z, Hu B, Lv Q, Wang Z
Cellular signalling 2024 May;117:111073
Cellular signalling 2024 May;117:111073
Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.
Wang R, Mi Y, Ni J, Wang Y, Ding L, Ran X, Sun Q, Tan SY, Koeffler HP, Feng N, Chen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(9):e2304939
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X, Zhu C, Liu P, Liu S, Ren L, Lu R, Hou J, Gao Y, Wang X, Pan Y
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration.
Yang Y, Song B, Guo M, Gao J, Jiang L, Li Q, Liu Y, Cao J
Ecotoxicology and environmental safety 2024 Mar 1;272:116076
Ecotoxicology and environmental safety 2024 Mar 1;272:116076
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731
Brain research 2024 Mar 1;1826:148731
RARRES1 identified by comprehensive bioinformatic analysis and experimental validation as a promising biomarker in Skin Cutaneous Melanoma.
Liu M, Bai R, Zhang G, Liu X, Wang Z, He K, Gan X, Zhou X, Yin P, Zheng Y, Wang G
Scientific reports 2024 Jun 19;14(1):14113
Scientific reports 2024 Jun 19;14(1):14113
Epiberberine induced p53/p21-dependent G2/M cell cycle arrest and cell apoptosis in gastric cancer cells by activating γ-aminobutyric acid receptor- β3.
Li M, Yang J, Li J, Zhou Y, Li X, Ma Z, Li X, Ma H, Ye X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155198
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155198
Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinoma.
Yang Z, Yuan H, He H, Qi S, Zhu X, Hu X, Jin M, Zhang XX, Yuan ZG
International immunopharmacology 2024 Jan 5;126:111227
International immunopharmacology 2024 Jan 5;126:111227
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
Chen Y, Han Z, Zhang L, Gao C, Wei J, Yang X, Han Y, Li Y, Zhang C, Wei Y, Dong J, Xun W, Sun W, Zhang T, Zhang H, Chen J, Yuan P
Journal of translational medicine 2024 Jan 4;22(1):21
Journal of translational medicine 2024 Jan 4;22(1):21
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Mitophagy-Mediated Tumor Dormancy Protects Cancer Cells from Chemotherapy.
Sun Y, Chen Y, Liu Z, Wang J, Bai J, Du R, Long M, Shang Z
Biomedicines 2024 Jan 28;12(2)
Biomedicines 2024 Jan 28;12(2)
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Zhu W, Gui X, Zhou Y, Gao X, Zhang R, Li Q, Zhang H, Zhao J, Cui X, Gao G, Tang H, Huan C, Pan D, Song H, Zhou Z, Shen W
Experimental eye research 2024 Feb;239:109753
Experimental eye research 2024 Feb;239:109753
Discovery of Novel Antitumor Small-Molecule Agent with Dual Action of CDK2/p-RB and MDM2/p53.
Liu Z, Yang Y, Sun X, Ma R, Zhang W, Wang W, Yang G, Wang H, Zhang J, Wang Y, Tian J
Molecules (Basel, Switzerland) 2024 Feb 4;29(3)
Molecules (Basel, Switzerland) 2024 Feb 4;29(3)
ANP32B inhibition suppresses the growth of prostate cancer cells by regulating c-Myc signaling.
Zhou C, Ma H, Yu W, Zhou Y, Zhang X, Meng Y, Chen C, Zhang J, Shi G
Biochemical and biophysical research communications 2024 Feb 26;698:149543
Biochemical and biophysical research communications 2024 Feb 26;698:149543
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Zhang C, Yu Z, Yang S, Liu Y, Song J, Mao J, Li M, Zhao Y
Molecular cancer 2024 Feb 14;23(1):33
Molecular cancer 2024 Feb 14;23(1):33
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Xu J, Wu X, Zhu H, Zhu Y, Du K, Deng X, Wang C
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling.
Yu Y, Fan Y, Mei W, Xu X, Chen Y, Zhao Y, Ruan B, Shen Z, Lu Y, Zheng S, Jie W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117013
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117013
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Gao Y, Hou J, Fei X, Ren L, Lu R, Liu P, Liu S, Zhu C, Wang X, Pan Y
Cellular signalling 2024 Aug;120:111227
Cellular signalling 2024 Aug;120:111227
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
Liu J, Dong X, Xie R, Tang Y, Thomas AM, Li S, Liu S, Yu M, Qin H
Placenta 2024 Apr;149:18-28
Placenta 2024 Apr;149:18-28
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
Yang L, Ruan Y, Xu H
BMC cancer 2024 Apr 29;24(1):544
BMC cancer 2024 Apr 29;24(1):544
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Chen SJ, Yu F, Feng X, Li Q, Jiang YH, Zhao LQ, Cheng PP, Wang M, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
Sun Y, Chen Y, Zhao H, Wang J, Liu Y, Bai J, Hu C, Shang Z
iScience 2024 Apr 19;27(4):109340
iScience 2024 Apr 19;27(4):109340
Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs).
Ling L, Shu H, Huang Y, Hou J, Hua Y
Stem cells international 2023;2023:7074703
Stem cells international 2023;2023:7074703
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
SHCBP1 Promotes the Proliferation of Breast Cancer Cells by Inhibiting CXCL2.
Yu X, Feng G, Nian R, Han S, Ke M, Wang L, Li W, Tian S, Lu H
Journal of Cancer 2023;14(18):3444-3456
Journal of Cancer 2023;14(18):3444-3456
Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer.
Zheng C, Ren Z, Chen H, Yuan X, Suye S, Yin H, Fu C
Journal of Cancer 2023;14(14):2670-2685
Journal of Cancer 2023;14(14):2670-2685
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.
Shi B, Ge F, Cai L, Yang Y, Guo X, Wu R, Fan Z, Cao B, Wang N, Si Y, Lin X, Dong W, Sun H
Frontiers in immunology 2023;14:1247288
Frontiers in immunology 2023;14:1247288
Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway.
Wang R, Hou Y, Geng G, Zhu X, Wang Z, Cai W, Ye J, Zhao S, Mi Y, Jiang J
American journal of cancer research 2023;13(2):623-637
American journal of cancer research 2023;13(2):623-637
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.
Xu H, Li L, Wang S, Wang Z, Qu L, Wang C, Xu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940
Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
Guo Y, Shao J, Zhang R, Han M, Kong L, Liu Z, Li H, Wei D, Lu M, Zhang S, Zhang C, Wei H, Chen Z, Bian H
International journal of molecular sciences 2023 Sep 7;24(18)
International journal of molecular sciences 2023 Sep 7;24(18)
In silico protein interaction screening uncovers DONSON's role in replication initiation.
Lim Y, Tamayo-Orrego L, Schmid E, Tarnauskaite Z, Kochenova OV, Gruar R, Muramatsu S, Lynch L, Schlie AV, Carroll PL, Chistol G, Reijns MAM, Kanemaki MT, Jackson AP, Walter JC
Science (New York, N.Y.) 2023 Sep 22;381(6664):eadi3448
Science (New York, N.Y.) 2023 Sep 22;381(6664):eadi3448
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
Guo Z, Guo L
Experimental cell research 2023 Sep 15;430(2):113714
Experimental cell research 2023 Sep 15;430(2):113714
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway.
Wang L, Yue Y, Zhang L, Jing M, Ma M, Liu C, Li Y, Xu S, Wang K, Wang X, Fan J, Zhang M
Cellular oncology (Dordrecht, Netherlands) 2023 Oct;46(5):1317-1332
Cellular oncology (Dordrecht, Netherlands) 2023 Oct;46(5):1317-1332
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.
Chen L, Liang B, Xia S, Wang F, Li Z, Shao J, Zhang Z, Chen A, Zheng S, Zhang F
British journal of pharmacology 2023 Oct;180(19):2577-2598
British journal of pharmacology 2023 Oct;180(19):2577-2598
Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.
Sun L, Xing G, Wang W, Ma X, Bu X
Journal of dental sciences 2023 Oct;18(4):1588-1597
Journal of dental sciences 2023 Oct;18(4):1588-1597
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
Zhang M, Zhu LZ, Yang CJ, Yan JX, Wang ZP, Bai YP, Peng LZ, Luo HB, Zhang ZJ, Li L, Xu CR, Liu YQ
Bioorganic chemistry 2023 Oct;139:106652
Bioorganic chemistry 2023 Oct;139:106652
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.
He Y, Yang P, Yuan T, Zhang L, Yang G, Jin J, Yu T
International journal of molecular sciences 2023 Oct 18;24(20)
International journal of molecular sciences 2023 Oct 18;24(20)
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M
Aging 2023 Oct 17;15(20):11052-11066
Aging 2023 Oct 17;15(20):11052-11066
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004
European journal of pharmacology 2023 Oct 15;957:176004
IL-7 promotes CD19-directed CAR-T cells proliferation through miRNA-98-5p by targeting CDKN1A.
Yang LR, Li L, Meng MY, Li TT, Zhao YY, Yang SL, Gao H, Tang WW, Yang Y, Yang LL, Wang WJ, Liao LW, Hou ZL
International immunopharmacology 2023 Nov;124(Pt B):110974
International immunopharmacology 2023 Nov;124(Pt B):110974
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Wang S, Zhang X, Lei H, Song L, Huang Y, Kang T, Zhang M, Wang N, Yang P, Feng S, Wang J, Bai R, Wang N, Wang W, Zheng Y
Molecular carcinogenesis 2023 May;62(5):613-627
Molecular carcinogenesis 2023 May;62(5):613-627
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A
Oncogene 2023 May;42(20):1607-1619
Oncogene 2023 May;42(20):1607-1619
Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter.
Zhang H, Han J, Zhang J, Miao J, Li F, Tang K, Zhou K, Duan B, Li W, Cheng J, Sun Y, Hou N, Huang C
Cell death discovery 2023 May 8;9(1):152
Cell death discovery 2023 May 8;9(1):152
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Jin Y, Zhao L, Wang S, Zhang X, Quan J, Lin Z, Piao J
Carcinogenesis 2023 May 26;44(2):129-142
Carcinogenesis 2023 May 26;44(2):129-142
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Zhang X, Wang G, Gong Y, Zhao L, Song P, Zhang H, Zhang Y, Ju H, Wang X, Wang B, Ren H, Zhu X, Dong Y
iScience 2023 May 19;26(5):106639
iScience 2023 May 19;26(5):106639
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
Yang J, Hasenbilige, Bao S, Luo S, Jiang L, Li Q, Kong Y, Cao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113609
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113609
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma.
Li H, Ge N, Guan X, Han C, Li Y, Shen L, Chen M, Zhang B, Qu C, Zou W
Steroids 2023 Jun;194:109224
Steroids 2023 Jun;194:109224
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Sun Y, Weng J, Chen X, Ma S, Zhang Y, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
ASRGL1 downregulation suppresses hepatocellular carcinoma tumorigenesis in a CDK1-dependent manner.
Wang X, Wang Y, Yang L, Yuan J, Shen W, Zhang W, Wang J, Tao K
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Jul;55(7):955-966
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Jul;55(7):955-966
Metformin synergistically enhances the antitumour activity of Lenvatinib in hepatocellular carcinoma by altering AKT-FOXO3 signalling pathway.
Cheng Y, Zhan P, Lu J, Lu Y, Luo C, Cen X, Wang F, Xie C, Yin Z
Liver international : official journal of the International Association for the Study of the Liver 2023 Jul;43(7):1577-1592
Liver international : official journal of the International Association for the Study of the Liver 2023 Jul;43(7):1577-1592
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Zhao D, Gao Y, Su Y, Zhou Y, Yang T, Li Y, Wang Y, Sun Y, Chen L, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Pharmacological research 2023 Jan;187:106590
Pharmacological research 2023 Jan;187:106590
Triptolide inhibits intrahepatic cholangiocarcinoma growth by suppressing glycolysis via the AKT/mTOR pathway.
Li L, Wang C, Qiu Z, Deng D, Chen X, Wang Q, Meng Y, Zhang B, Zheng G, Hu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154575
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154575
MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
Li X, Xie S, Xia Q, Yan J, Chen S, Shen J
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338221150544
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338221150544
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Yin W, Fu X, Chang W, Han L, Meng J, Cao A, Ren X, Fan Z, Zhou S
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.
Yan X, Wang D, Ning Z, Meng ZQ
Discover oncology 2023 Feb 23;14(1):26
Discover oncology 2023 Feb 23;14(1):26
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Deng L, Yang L, Zhu S, Li M, Wang Y, Cao X, Wang Q, Guo L
Cell death discovery 2023 Feb 2;9(1):40
Cell death discovery 2023 Feb 2;9(1):40
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
He Y, Luo M, Lei S, Zeng Z, Chen T, Wu Y, Wang D, Wang L, Wang L
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
Shi Q, Li S, Lyu Q, Zhang S, Bai Y, Ma J
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.
Liu M, Zhang G, Wang Z, Liu X, He K, Luo R, Duan Q, Bai R, Wang Y, Du W, Zheng Y, Shao Y
The Journal of investigative dermatology 2023 Dec;143(12):2366-2377.e7
The Journal of investigative dermatology 2023 Dec;143(12):2366-2377.e7
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Artesunate and cisplatin synergistically inhibit HNSCC cell growth and promote apoptosis with artesunate‑induced decreases in Rb and phosphorylated Rb levels.
Okamoto H, Yoshikawa K, Shimada A, Sano R, Inukai D, Yamanaka S, Suzuki S, Ueda R, Ueda H, Fujimoto Y, Ogawa T
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
Sanggenon C inhibits cell proliferation and induces apoptosis by regulating the MIB1/DAPK1 axis in glioblastoma.
Chang H, Hou J, Shao Y, Xu M, Weng X, Du Y, Shi J, Zhang L, Cui H
MedComm 2023 Aug;4(4):e281
MedComm 2023 Aug;4(4):e281
221S-1a inhibits endothelial proliferation in pathological angiogenesis through ERK/c-Myc signaling.
Yao X, Xue Y, Ma Q, Bai Y, Jia P, Zhang Y, Lai B, He S, Ma Q, Zhang J, Tian H, Yin Q, Zheng X, Zheng X
European journal of pharmacology 2023 Aug 5;952:175805
European journal of pharmacology 2023 Aug 5;952:175805
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Li GH, Liu X, Feng LJ, Zhang L
Neoplasma 2023 Aug 20;
Neoplasma 2023 Aug 20;
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Wu H, Wu L, Xiao L, Gu Y, Liu H, Zhang L, Zhang M, Qi L
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Zhang D, Fu Y, Liu Y, Wu Y, Chen J, Zhang L, Wang R, Chen Z, Liu T
International journal of molecular sciences 2023 Apr 28;24(9)
International journal of molecular sciences 2023 Apr 28;24(9)
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Wang X, Li Y, Li Y, Liu P, Liu S, Pan Y
Stem cells international 2022;2022:3242482
Stem cells international 2022;2022:3242482
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Xiong G, Feng Y, Yi X, Zhang X, Li X, Yang L, Yi Z, Sai B, Yang Z, Zhang Q, Kuang Y, Zhu Y
Frontiers in immunology 2022;13:989263
Frontiers in immunology 2022;13:989263
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
Liu Y, Song X, Li C, Hu H, Li W, Wang L, Hu J, Liao C, Liang H, He Z, Ye L
Frontiers in immunology 2022;13:872958
Frontiers in immunology 2022;13:872958
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Liao H, Zhang L, Lu S, Li W, Dong W
Frontiers in genetics 2022;13:848926
Frontiers in genetics 2022;13:848926
Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach.
Fei X, Liu S, Liu P, Wang X, Zhu C, Hou J, Cai J, Pan Y
Frontiers in oncology 2022;12:1043161
Frontiers in oncology 2022;12:1043161
tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis.
Liu Y, Zhou J, Li X, Zhang X, Shi J, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zheng J, Liu RJ, Su B, Ye Y, Flavell RA, Yi C, Wu Y, Li HB
Nature immunology 2022 Oct;23(10):1433-1444
Nature immunology 2022 Oct;23(10):1433-1444
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cui X, Pei X, Wang H, Feng P, Qin H, Liu S, Yan Q, Liu J
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
Effect of miRNA-200b on the proliferation of liver cancer cells via targeting SMYD2/p53 signaling pathway.
Fang W, Song L, Li Z, Meng P, Zuo S, Liu S
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Oct 28;47(10):1303-1314
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Oct 28;47(10):1303-1314
Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage.
Pan J, Li X, Liu H, Wang C, Xu S, Xu B, Deng Y, Yang T, Liu W
Ecotoxicology and environmental safety 2022 Oct 15;245:114099
Ecotoxicology and environmental safety 2022 Oct 15;245:114099
High expression of HOXA4 in patients with glioma indicates unfavorable clinical outcomes.
Yu Z, Liu Z, Lian X, Cheng X, Liu B, Zhang B, Wang H, Wang J, Li A, Ren Z, Pang B, Qian R, Gao Y
Cell cycle (Georgetown, Tex.) 2022 Nov;21(22):2387-2402
Cell cycle (Georgetown, Tex.) 2022 Nov;21(22):2387-2402
Porcine Circovirus 2 Activates the PERK-Reactive Oxygen Species Axis To Induce p53 Phosphorylation with Subsequent Cell Cycle Arrest at S Phase in Favor of Its Replication.
Deng Z, Sun R, Han X, Zhang Y, Zhou Y, Shan Y, Xu J, Li X, He F, Fang W
Journal of virology 2022 Nov 23;96(22):e0127422
Journal of virology 2022 Nov 23;96(22):e0127422
Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.
Han M, Li Y, Guo Y, Zhu W, Jiang J
International journal of molecular sciences 2022 Nov 13;23(22)
International journal of molecular sciences 2022 Nov 13;23(22)
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Zhou T, Chen T, Lai B, Zhang W, Luo X, Xia D, Fu W, Xu J
Cellular and molecular life sciences : CMLS 2022 May 2;79(5):268
Cellular and molecular life sciences : CMLS 2022 May 2;79(5):268
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
Guo J, Chen LW, Huang ZQ, Guo JS, Li H, Shan Y, Chen ZR, Yan YM, Zhu JN, Guo HM, Fang XH, Shan ZX
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626
Cell death & disease 2022 Jul 19;13(7):626
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
Zhou Q, Lin J, Yan Y, Meng S, Liao H, Chen R, He G, Zhu Y, He C, Mao K, Wang J, Zhang J, Zhou Z, Xiao Z
Journal of experimental & clinical cancer research : CR 2022 Jan 7;41(1):13
Journal of experimental & clinical cancer research : CR 2022 Jan 7;41(1):13
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Wu X, Wang Y, Fan X, Xu X, Sun W
Aging 2022 Jan 7;14(1):410-429
Aging 2022 Jan 7;14(1):410-429
Tetracaine hydrochloride induces cell cycle arrest in melanoma by downregulating hnRNPA1.
Huang X, Chen Y, Yi J, Yi P, Jia J, Liao Y, Feng J, Jiang X
Toxicology and applied pharmacology 2022 Jan 1;434:115810
Toxicology and applied pharmacology 2022 Jan 1;434:115810
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Huang Y, Zou Y, Jie Z
Experimental and therapeutic medicine 2022 Feb;23(2):118
Experimental and therapeutic medicine 2022 Feb;23(2):118
Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.
Zhuang J, Cheng G, Huang J, Guo H, Lai Y, Wang J, Shan Z, Zheng S
BMC cardiovascular disorders 2022 Feb 23;22(1):69
BMC cardiovascular disorders 2022 Feb 23;22(1):69
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.
Yu J, Qi H, Wang Z, Zhang Z, Song E, Song W, An R
Cell biology international 2022 Dec;46(12):2246-2256
Cell biology international 2022 Dec;46(12):2246-2256
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Yang W, Guo C, Herman JG, Zhu C, Lv H, Su X, Zhang L, Zhang M, Guo M
Clinical epigenetics 2022 Dec 2;14(1):164
Clinical epigenetics 2022 Dec 2;14(1):164
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.
Zhang G, Liu B, Shang H, Wu G, Wu D, Wang L, Li S, Wang Z, Wang S, Yuan J
BMC medical genomics 2022 Aug 15;15(1):180
BMC medical genomics 2022 Aug 15;15(1):180
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2.
Sun Z, Liu Y, Hu R, Wang T, Li Y, Liu N
International journal of molecular medicine 2022 Apr;49(4)
International journal of molecular medicine 2022 Apr;49(4)
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Zhao N, Gui X, Fang Q, Zhang R, Zhu W, Zhang H, Li Q, Zhou Y, Zhao J, Cui X, Gao G, Tang H, Shen N, Chen T, Song H, Shen W
Journal of nanobiotechnology 2022 Apr 2;20(1):174
Journal of nanobiotechnology 2022 Apr 2;20(1):174
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
Feng X, Jiang J, Sun L, Zhou Q
Toxicology and applied pharmacology 2022 Apr 1;440:115940
Toxicology and applied pharmacology 2022 Apr 1;440:115940
MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.
Song H, Zhuang L, Xu X, Shi J, Hu W, Liu Z, Shi S
Frontiers in medicine 2021;8:777563
Frontiers in medicine 2021;8:777563
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008
Frontiers in molecular biosciences 2021;8:705008
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Liu C, Chi K, Geng X, Hong Q, Mao Z, Huang Q, Liu D, Wang Y, Zhang Y, Zhou F, Cai G, Chen X, Sun X
Frontiers in medicine 2021;8:655787
Frontiers in medicine 2021;8:655787
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Zhu L, Zheng Y, Hu R, Hu C
BioMed research international 2021;2021:5486131
BioMed research international 2021;2021:5486131
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Zhang P, Yang Q
Frontiers in genetics 2021;12:682856
Frontiers in genetics 2021;12:682856
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256
Frontiers in pharmacology 2021;12:639256
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Wang S, Xu J, Guo Y, Cai Y, Ren X, Zhu W, Geng M, Meng L, Jiang C, Lu S
Frontiers in immunology 2021;12:619392
Frontiers in immunology 2021;12:619392
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Wang D, Li Z, Yin H
Frontiers in oncology 2021;11:751903
Frontiers in oncology 2021;11:751903
CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
Li H, Weng Y, Wang S, Wang F, Wang Y, Kong P, Zhang L, Cheng C, Cui H, Xu E, Wei S, Guo D, Chen F, Bi Y, Meng Y, Cheng X, Cui Y
Frontiers in oncology 2021;11:734655
Frontiers in oncology 2021;11:734655
NUDT21 Promotes Tumor Growth and Metastasis Through Modulating SGPP2 in Human Gastric Cancer.
Zhu Y, Zhang R, Zhang Y, Cheng X, Li L, Wu Z, Ding K
Frontiers in oncology 2021;11:670353
Frontiers in oncology 2021;11:670353
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Zhu X, Li R, Wang C, Zhou S, Fan Y, Ma S, Gao D, Gai N, Yang J
Frontiers in oncology 2021;11:661184
Frontiers in oncology 2021;11:661184
Circ_0089823 reinforces malignant behaviors of non-small cell lung cancer by acting as a sponge for microRNAs targeting SOX4().
Li J, Zhu Z, Li S, Han Z, Meng F, Wei L
Neoplasia (New York, N.Y.) 2021 Sep;23(9):887-897
Neoplasia (New York, N.Y.) 2021 Sep;23(9):887-897
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma.
Zheng S, Liu Y, Sun H, Jia J, Wu T, Ding R, Cheng X
European journal of histochemistry : EJH 2021 Sep 3;65(3)
European journal of histochemistry : EJH 2021 Sep 3;65(3)
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Ni Y, Yang Z, Agbana YL, Bai H, Wang L, Yang L, Yi Z, Cheng J, Zhang Q, Kuang Y, Zhu Y
Cancer science 2021 Oct;112(10):4075-4086
Cancer science 2021 Oct;112(10):4075-4086
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
Ji J, Wang Z, Sun W, Li Z, Cai H, Zhao E, Cui H
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7.
Yan J, Yang Y, Fan X, Tang Y, Tang Z
Genes 2021 May 8;12(5)
Genes 2021 May 8;12(5)
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Tao Y, Zhang J, Chen L, Liu X, Yao M, Zhang H
Cell death & disease 2021 May 18;12(6):510
Cell death & disease 2021 May 18;12(6):510
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
Kishi S, Nishiguchi Y, Honoki K, Mori S, Fujiwara-Tani R, Sasaki T, Fujii K, Kawahara I, Goto K, Nakashima C, Kido A, Tanaka Y, Luo Y, Kuniyasu H
International journal of molecular sciences 2021 May 13;22(10)
International journal of molecular sciences 2021 May 13;22(10)
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Xiao Y, Deng J, Li C, Gong X, Gui Z, Huang J, Zhang Y, Liu Y, Ye X, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153488
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153488
Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.
Lin Z, Zhao C, Lei Z, Zhang Y, Huang R, Lin B, Dong Y, Zhang H, Li J, Li X
Stem cell research & therapy 2021 Jun 10;12(1):341
Stem cell research & therapy 2021 Jun 10;12(1):341
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Journal of cellular and molecular medicine 2021 Jul;25(13):5976-5987
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Du T, Wang D, Wan X, Xu J, Xiao Q, Liu B
Oncology letters 2021 Jul;22(1):516
Oncology letters 2021 Jul;22(1):516
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Li Y, Wang Y, Li J, Ling Z, Chen W, Zhang L, Hu Q, Wu T, Cheng B, Wang Y, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
Wang H, Fu Y
BMC cancer 2021 Jul 30;21(1):871
BMC cancer 2021 Jul 30;21(1):871
Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes.
Sun X, Fu P, Xie L, Chai S, Xu Q, Zeng L, Wang X, Jiang N, Sang M
International journal of molecular medicine 2021 Jan;47(1):335-345
International journal of molecular medicine 2021 Jan;47(1):335-345
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Li Q, Chu Z, Geng S
Cancer investigation 2021 Jan;39(1):84-97
Cancer investigation 2021 Jan;39(1):84-97
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
Liu Y, Nie X, Zhu J, Wang T, Li Y, Wang Q, Sun Z
Journal of cellular and molecular medicine 2021 Jan;25(2):1221-1237
Journal of cellular and molecular medicine 2021 Jan;25(2):1221-1237
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Liu C, Yu M, Li Y, Wang H, Xu C, Zhang X, Li M, Guo H, Ma D, Guo X
Cancer medicine 2021 Jan;10(1):337-349
Cancer medicine 2021 Jan;10(1):337-349
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Ma J, Chen X, Lin M, Wang Z, Wu Y, Li J
Cancer cell international 2021 Jan 21;21(1):65
Cancer cell international 2021 Jan 21;21(1):65
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Ma L, Li C, Lian S, Xu B, Yuan J, Lu J, Yang H, Guo J, Ji H
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Li MJ, Xiong D, Huang H, Wen ZY
Biomedical and environmental sciences : BES 2021 Feb 20;34(2):139-151
Biomedical and environmental sciences : BES 2021 Feb 20;34(2):139-151
Ropivacaine Induces Cell Cycle Arrest in the G0/G1 Phase and Apoptosis of PC12 Cells via Inhibiting Mitochondrial STAT3 Translocation.
Zeng L, Li A, Zhang Z, Zhang F, Chen H, Wang Y, Ding X, Luo H
Inflammation 2021 Dec;44(6):2362-2376
Inflammation 2021 Dec;44(6):2362-2376
Xenobiotic Receptor CAR Is Highly Induced in Psoriasis and Promotes Keratinocyte Proliferation.
Lai B, Xie X, Li F, Cui Q, Dang E, Luo W, Wang N, Zheng Y, Wang G, Xiao L, Wang N
The Journal of investigative dermatology 2021 Dec;141(12):2895-2907.e7
The Journal of investigative dermatology 2021 Dec;141(12):2895-2907.e7
S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
Liu C, Du H, Wang Y, Gong N, Qi W, Zhou X, Shi L
Molecular immunology 2021 Dec;140:35-46
Molecular immunology 2021 Dec;140:35-46
MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.
Liu H, Chi Z, Jin H, Yang W
Bioengineered 2021 Dec;12(1):1611-1626
Bioengineered 2021 Dec;12(1):1611-1626
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Chen C, Wang YS, Zhang ET, Li GA, Liu WY, Li Y, Jin YH
International journal of molecular sciences 2021 Dec 6;22(23)
International journal of molecular sciences 2021 Dec 6;22(23)
PKMYT1, exacerbating the progression of clear cell renal cell carcinoma, is implied as a biomarker for the diagnosis and prognosis.
Chen J, Hua X, Chen H, Qiu X, Xiao H, Ge S, Liang C, Zhou Q
Aging 2021 Dec 27;13(24):25778-25798
Aging 2021 Dec 27;13(24):25778-25798
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Liao X, Wu C, Shao Z, Zhang S, Zou Y, Wang K, Ha Y, Xing J, Zheng A, Shen Z, Zheng S, Guo J, Jie W
Stem cell reviews and reports 2021 Aug;17(4):1374-1389
Stem cell reviews and reports 2021 Aug;17(4):1374-1389
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells.
Qi MM, He PZ, Zhang L, Dong WG
World journal of gastrointestinal oncology 2021 Aug 15;13(8):893-914
World journal of gastrointestinal oncology 2021 Aug 15;13(8):893-914
Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells.
Xiao M, Tang N, Yan Y, Li Z, Shi S, He S, Chen Z, Cao K, Chen J, Zhou J, Chen X
Melanoma research 2021 Aug 1;31(4):309-318
Melanoma research 2021 Aug 1;31(4):309-318
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Wang Q, Dong Z, Su J, Huang J, Xiao P, Tian L, Chen Y, Ma L, Chen X
Biochemical and biophysical research communications 2021 Apr 16;549:1-7
Biochemical and biophysical research communications 2021 Apr 16;549:1-7
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Mao Y, Li W, Hua B, Gu X, Pan W, Chen Q, Xu B, Wang Z, Lu C
BioMed research international 2020;2020:2406159
BioMed research international 2020;2020:2406159
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
Jia M, Zheng D, Wang X, Zhang Y, Chen S, Cai X, Mo L, Hu Z, Li H, Zhou Z, Li J
International journal of medical sciences 2020;17(11):1652-1664
International journal of medical sciences 2020;17(11):1652-1664
Tissue Inhibitor of Metalloproteinases-2 Mediates Kidney Injury during Sepsis.
Wen X, Zhang J, Wan X, Frank AA, Qu X, Kellum JA
Nephron 2020;144(12):644-649
Nephron 2020;144(12):644-649
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
Zheng YW, Li ZH, Lei L, Liu CC, Wang Z, Fei LR, Yang MQ, Huang WJ, Xu HT
Frontiers in oncology 2020;10:180
Frontiers in oncology 2020;10:180
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Gu C, Zhao K, Zhou N, Liu F, Xie F, Yu S, Feng Y, Chen L, Yang J, Tian F, Jiang G
Cell death & disease 2020 Sep 10;11(9):733
Cell death & disease 2020 Sep 10;11(9):733
LncRNA IDH1-AS1 suppresses cell proliferation and tumor growth in glioma.
Wang J, Quan Y, Lv J, Dong Q, Gong S
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):556-564
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):556-564
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Liu A, Zuo Z, Liu L, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
SLC25A10 performs an oncogenic role in human osteosarcoma.
Wang G, Xia J, Chen C, Qiu J, Sun P, Peng Z, Chen X, Xu B
Oncology letters 2020 Oct;20(4):2
Oncology letters 2020 Oct;20(4):2
Minichromosome maintenance protein 5 is an important pathogenic factor of oral squamous cell carcinoma.
Hao M, Wang H, Zhang C, Li C, Wang X
Oncology letters 2020 Oct;20(4):109
Oncology letters 2020 Oct;20(4):109
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Jin C, Li Y, Su Y, Guo Z, Wang X, Wang S, Zhang F, Zhang Z, Shao J, Zheng S
Cell death & disease 2020 Oct 11;11(10):844
Cell death & disease 2020 Oct 11;11(10):844
Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Yang Y, Zhang G, Guo F, Li Q, Luo H, Shu Y, Shen Y, Gan J, Xu L, Yang H
Cell reports 2020 Nov 3;33(5):108340
Cell reports 2020 Nov 3;33(5):108340
MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3.
Li H, Pan R, Lu Q, Ren C, Sun J, Wu H, Wen J, Chen H
International journal of molecular medicine 2020 May;45(5):1317-1326
International journal of molecular medicine 2020 May;45(5):1317-1326
LINC00963 targeting miR-128-3p promotes acute kidney injury process by activating JAK2/STAT1 pathway.
Xie LB, Chen B, Liao X, Chen YF, Yang R, He SR, Pei LJ, Jiang R
Journal of cellular and molecular medicine 2020 May;24(10):5555-5564
Journal of cellular and molecular medicine 2020 May;24(10):5555-5564
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Jin X, Ge LP, Li DQ, Shao ZM, Di GH, Xu XE, Jiang YZ
Molecular cancer 2020 May 11;19(1):87
Molecular cancer 2020 May 11;19(1):87
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Liu L, Deng Y, Cai Y, Lu P, Guo Y, Zhang C, Li Q, Zhang T, Han M, Xu G
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Zeng ZM, Du HY, Xiong L, Zeng XL, Zhang P, Cai J, Huang L, Liu AW
Life sciences 2020 Mar 1;244:117342
Life sciences 2020 Mar 1;244:117342
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Peng F, Li G, Xie Y, Yin HY, Li XJ, Yang YD
Journal of food biochemistry 2020 Jun;44(6):e13222
Journal of food biochemistry 2020 Jun;44(6):e13222
Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancer.
Luo F, Zhao Y, Liu J
The international journal of biochemistry & cell biology 2020 Jun;123:105750
The international journal of biochemistry & cell biology 2020 Jun;123:105750
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.
Wang J, Wang L, Chen S, Peng H, Xiao L, E Du, Liu Y, Lin D, Wang Y, Xu Y, Yang K
Gene 2020 Jun 20;744:144608
Gene 2020 Jun 20;744:144608
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Miao J, Hou N, Yang W, Jiang Q, Xue W, Wang X, Zhang H, Xiong X, Wang L, Zhao L, Huang C
Anti-cancer drugs 2020 Jul;31(6):583-591
Anti-cancer drugs 2020 Jul;31(6):583-591
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
Zhou H, Xiong Y, Zhang G, Liu Z, Li L, Hou S, Zhou T
Bioscience reports 2020 Jul 31;40(7)
Bioscience reports 2020 Jul 31;40(7)
HOTAIR-EZH2 inhibitor AC1Q3QWB upregulates CWF19L1 and enhances cell cycle inhibition of CDK4/6 inhibitor palbociclib in glioma.
Shi J, Lv S, Wu M, Wang X, Deng Y, Li Y, Li K, Zhao H, Zhu X, Ye M
Clinical and translational medicine 2020 Jan;10(1):182-198
Clinical and translational medicine 2020 Jan;10(1):182-198
ASPM promotes glioblastoma growth by regulating G1 restriction point progression and Wnt-β-catenin signaling.
Chen X, Huang L, Yang Y, Chen S, Sun J, Ma C, Xie J, Song Y, Yang J
Aging 2020 Jan 6;12(1):224-241
Aging 2020 Jan 6;12(1):224-241
MiR-23a-3p promoted G1/S cell cycle transition by targeting protocadherin17 in hepatocellular carcinoma.
Xiang Y, Yang Y, Lin C, Wu J, Zhang X
Journal of physiology and biochemistry 2020 Feb;76(1):123-134
Journal of physiology and biochemistry 2020 Feb;76(1):123-134
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Liu Y, Zhang M, He T, Yang W, Wang L, Zhang L, Guo M
Clinical epigenetics 2020 Feb 10;12(1):22
Clinical epigenetics 2020 Feb 10;12(1):22
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Yuan Q, Yang F, Dai S, Wang Z, Xu Y, Xu BC, Sun Y, Zheng B, Zhao Y, Wang W, Liu B, Wang J, Cui S, Cao S, Zhang R, Xue L, Wei S, Xue M, Xu T, Xu F, Chen Y
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Zhang L, Wang Z, Kong D, Zhao X, Chen X, Chai W
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro.
Hao P, Yue F, Xian X, Ren Q, Cui H, Wang Y
Life sciences 2020 Aug 1;254:117632
Life sciences 2020 Aug 1;254:117632
Mechanism of inhibiting proliferation of hepatocellular carcinoma Hepa1-6 cells by embryonic stem cell-conditioned medium.
Li L, Zheng Y, Zheng Q, Jiang J
Experimental and therapeutic medicine 2020 Apr;19(4):2406-2414
Experimental and therapeutic medicine 2020 Apr;19(4):2406-2414
Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer.
Yang Y, Wei Q, Tang Y, Yuanyuan Wang, Luo Q, Zhao H, He M, Wang H, Zeng Q, Lu W, Xu J, Liu T, Yi P
Cancer letters 2020 Apr 10;475:43-52
Cancer letters 2020 Apr 10;475:43-52
Activation of CXCL5-CXCR2 axis promotes proliferation and accelerates G1 to S phase transition of papillary thyroid carcinoma cells and activates JNK and p38 pathways.
Cui D, Zhao Y, Xu J
Cancer biology & therapy 2019;20(5):608-616
Cancer biology & therapy 2019;20(5):608-616
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Zhao Y, Zhang Y, Vazirinejad Mehdiabad M, Zhou K, Chen Y, Li L, Guo J, Xu C
PloS one 2019;14(10):e0223232
PloS one 2019;14(10):e0223232
The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
Wei Y, Liu P, Li Q, Du J, Chen Y, Wang Y, Shi H, Wang Y, Zhang H, Xue W, Gao Y, Li D, Feng Y, Yan J, Han J, Zhang J
OncoTargets and therapy 2019;12:6361-6370
OncoTargets and therapy 2019;12:6361-6370
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W
Frontiers in pharmacology 2019;10:1238
Frontiers in pharmacology 2019;10:1238
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635
Cell proliferation 2019 Sep;52(5):e12635
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Wang D, Xu H, Wu B, Jiang S, Pan H, Wang R, Chen J
International journal of molecular medicine 2019 Sep;44(3):871-884
International journal of molecular medicine 2019 Sep;44(3):871-884
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Guo W, Li H, Liu H, Ma X, Yang S, Wang Z
Oncology reports 2019 Sep;42(3):1075-1089
Oncology reports 2019 Sep;42(3):1075-1089
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
Zheng F, Wang M, Li Y, Huang C, Tao D, Xie F, Zhang H, Sun J, Zhang C, Gu C, Wang Z, Jiang G
Cancer letters 2019 Sep 28;460:139-151
Cancer letters 2019 Sep 28;460:139-151
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, Shen W, Zhong M
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, Ye S, Ma Q, Wei J, Wu M, Huang X, Ma D, Gao Q
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Su D, Zhang D, Jin J, Ying L, Han M, Chen K, Li B, Wu J, Xie Z, Zhang F, Lin Y, Cheng G, Li JY, Huang M, Wang J, Wang K, Zhang J, Li F, Xiong L, Futreal A, Mao W
Nature communications 2019 Nov 7;10(1):5076
Nature communications 2019 Nov 7;10(1):5076
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
Shen Z, Liao X, Shao Z, Feng M, Yuan J, Wang S, Gan S, Ha Y, He Z, Jie W
BMC cancer 2019 Mar 22;19(1):262
BMC cancer 2019 Mar 22;19(1):262
miR-193a/b-3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells.
Ju B, Nie Y, Yang X, Wang X, Li F, Wang M, Wang C, Zhang H
Journal of cellular and molecular medicine 2019 Jun;23(6):3824-3832
Journal of cellular and molecular medicine 2019 Jun;23(6):3824-3832
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Lu GQ, Li XY, Mohamed O K, Wang D, Meng FH
European journal of medicinal chemistry 2019 Jun 1;171:282-296
European journal of medicinal chemistry 2019 Jun 1;171:282-296
Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses.
Jiang Y, Li C, Wu Q, An P, Huang L, Wang J, Chen C, Chen X, Zhang F, Ma L, Liu S, He H, Xie S, Sun Y, Liu H, Zhan Y, Tao Y, Liu Z, Sun X, Hu Y, Wang Q, Ye D, Zhang J, Zou S, Wang Y, Wei G, Liu Y, Shi Y, Eugene Chin Y, Hao Y, Wang F, Zhang X
Nature communications 2019 Jul 3;10(1):2935
Nature communications 2019 Jul 3;10(1):2935
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Zhou M, Wang A, Yin B, Wu D, Han S, Zhang W, Liu J, Sun K
Oncology reports 2019 Jan;41(1):579-589
Oncology reports 2019 Jan;41(1):579-589
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Yang DL, Gan ML, Tan Y, Ge GH, Li Q, Jiang YZ, Tang GQ, Li MZ, Wang JY, Li XW, Zhang SH, Zhu L
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation.
Tian R, Yao C, Yang C, Zhu Z, Li C, Zhi E, Wang J, Li P, Chen H, Yuan Q, He Z, Li Z
Stem cell research & therapy 2019 Jan 22;10(1):40
Stem cell research & therapy 2019 Jan 22;10(1):40
Baicalin inhibits proliferation and promotes apoptosis of vascular smooth muscle cells by regulating the MEG3/p53 pathway following treatment with ox‑LDL.
Liu Y, Jia L, Min D, Xu Y, Zhu J, Sun Z
International journal of molecular medicine 2019 Feb;43(2):901-913
International journal of molecular medicine 2019 Feb;43(2):901-913
Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma.
Yun D, Wang H, Wang Y, Chen Y, Zhao Z, Ma J, Ji Y, Huang Q, Chen J, Chen H, Lu D
EBioMedicine 2019 Feb;40:163-175
EBioMedicine 2019 Feb;40:163-175
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Wang S, Hu H, Zhong B, Shi D, Qing X, Cheng C, Deng X, Zhang Z, Shao Z
Cancer medicine 2019 Dec;8(17):7345-7358
Cancer medicine 2019 Dec;8(17):7345-7358
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691
Experimental cell research 2019 Dec 15;385(2):111691
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, Lin D, Yang K
Experimental cell research 2019 Dec 1;385(1):111669
Experimental cell research 2019 Dec 1;385(1):111669
Upregulation of miR‑95-3p inhibits growth of osteosarcoma by targeting HDGF.
Liu X, Ma W, Ma J, Xiao L, Hao D
Pathology, research and practice 2019 Aug;215(8):152492
Pathology, research and practice 2019 Aug;215(8):152492
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Zheng M, Tian C, Fan T, Xu B
Experimental eye research 2019 Aug;185:107681
Experimental eye research 2019 Aug;185:107681
Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.
Zhang Y, Xu L, Wang P, Jian H, Shi X, Jia M, Mo L, Hu Z, Li H, Li J
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1938-1947
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1938-1947
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, Tian J
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
Motor Neuron and Pancreas Homeobox 1 (MNX1) Is Involved in Promoting Squamous Cervical Cancer Proliferation via Regulating Cyclin E.
Xiao L, Hong L, Zheng W
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 22;25:6304-6312
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 22;25:6304-6312
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Pan JH, Zhou H, Zhu SB, Huang JL, Zhao XX, Ding H, Qin L, Pan YL
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Journal of cellular physiology 2019 Apr;234(4):4385-4395
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
MicroRNA-107 induces cell cycle arrests by directly targeting cyclin E1 in ovarian cancer.
Tang Z, Fang Y, Du R
Biochemical and biophysical research communications 2019 Apr 30;512(2):331-337
Biochemical and biophysical research communications 2019 Apr 30;512(2):331-337
Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice.
Liu D, Yin Z, Huang Q, Ren Y, Li D, Wang L, Cui S, Zhang Y, Ning Y, Lun L, Cai G, Bai X, Sun X, Chen X
Aging 2019 Apr 12;11(7):2031-2044
Aging 2019 Apr 12;11(7):2031-2044
Identification of Grade-associated MicroRNAs in Brainstem Gliomas Based on Microarray Data.
Chen X, Dong D, Pan C, Xu C, Sun Y, Geng Y, Kong L, Xiao X, Zhao Z, Zhou W, Huang L, Song Y, Zhang L
Journal of Cancer 2018;9(23):4463-4476
Journal of Cancer 2018;9(23):4463-4476
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production.
Wang Z, Wang Y, Wang S, Meng X, Song F, Huo W, Zhang S, Chang J, Li J, Zheng B, Liu Y, Zhang Y, Zhang W, Yu J
Frontiers in cellular and infection microbiology 2018;8:279
Frontiers in cellular and infection microbiology 2018;8:279
Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells.
Men L, Sun J, Ren D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(5):2185-2197
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(5):2185-2197
Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2.
Guo T, Song H, Zhao Z, Qi Z, Zhao S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1617-1627
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1617-1627
VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
Zhao L, Zhu Z, Yao C, Huang Y, Zhi E, Chen H, Tian R, Li P, Yuan Q, Xue Y, Wan Z, Yang C, Gong Y, He Z, Li Z
Cell cycle (Georgetown, Tex.) 2018;17(2):225-239
Cell cycle (Georgetown, Tex.) 2018;17(2):225-239
HOXA5 is a tumor suppressor gene that is decreased in gastric cancer.
Peng X, Zha L, Chen A, Wang Z
Oncology reports 2018 Sep;40(3):1317-1329
Oncology reports 2018 Sep;40(3):1317-1329
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer.
Xu X, Zheng Z, Jia L, Suo S, Liu B, Shao T, Tu Q, Hua Y, Xu H
Oncology letters 2018 Sep;16(3):3796-3804
Oncology letters 2018 Sep;16(3):3796-3804
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
Xie F, Li Y, Wang M, Huang C, Tao D, Zheng F, Zhang H, Zeng F, Xiao X, Jiang G
Molecular cancer 2018 Oct 3;17(1):144
Molecular cancer 2018 Oct 3;17(1):144
IL-2Rα up-regulation is mediated by latent membrane protein 1 and promotes lymphomagenesis and chemotherapy resistance in natural killer/T-cell lymphoma.
Wang L, Bi XW, Zhu YJ, He YZ, Lai QY, Xia ZJ, Cai QQ
Cancer communications (London, England) 2018 Oct 19;38(1):62
Cancer communications (London, England) 2018 Oct 19;38(1):62
Antifibrotic cardioprotection of berberine via downregulating myocardial IGF-1 receptor-regulated MMP-2/MMP-9 expression in diabetic rats.
Li G, Xing W, Zhang M, Geng F, Yang H, Zhang H, Zhang X, Li J, Dong L, Gao F
American journal of physiology. Heart and circulatory physiology 2018 Oct 1;315(4):H802-H813
American journal of physiology. Heart and circulatory physiology 2018 Oct 1;315(4):H802-H813
miR-155 accelerates proliferation of mouse hepatocytes during liver regeneration by directly targeting SOCS1.
Lin X, Chen L, Li H, Liu Y, Guan Y, Li X, Jia Z, Lin X, Jia J, Sun Y, Xiao D
American journal of physiology. Gastrointestinal and liver physiology 2018 Oct 1;315(4):G443-G453
American journal of physiology. Gastrointestinal and liver physiology 2018 Oct 1;315(4):G443-G453
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q
FEBS letters 2018 Nov;592(22):3696-3707
FEBS letters 2018 Nov;592(22):3696-3707
HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer.
Fu F, Wang T, Wu Z, Feng Y, Wang W, Zhou S, Ma X, Wang S
Cell death & disease 2018 May 22;9(6):594
Cell death & disease 2018 May 22;9(6):594
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Yun DP, Wang YQ, Meng DL, Ji YY, Chen JX, Chen HY, Lu DR
Oncology reports 2018 Mar;39(3):1011-1022
Oncology reports 2018 Mar;39(3):1011-1022
ANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1.
Xiong Z, Ye L, Zhenyu H, Li F, Xiong Y, Lin C, Wu X, Deng G, Shi W, Song L, Yuan Z, Wang X
Molecular oncology 2018 Jun;12(6):896-912
Molecular oncology 2018 Jun;12(6):896-912
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Zhang JR, Lu QB, Feng WB, Wang HP, Tang ZH, Cheng H, Du Q, Wang YB, Li KX, Sun HJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Zeng GZ, Wang Z, Zhao LM, Fan JT, Tan NH
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Motor neuron and pancreas homeobox 1/HLXB9 promotes sustained proliferation in bladder cancer by upregulating CCNE1/2.
Chen M, Wu R, Li G, Liu C, Tan L, Xiao K, Ye Y, Qin Z
Journal of experimental & clinical cancer research : CR 2018 Jul 16;37(1):154
Journal of experimental & clinical cancer research : CR 2018 Jul 16;37(1):154
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, Li Z, Ye X, Li X
Life sciences 2018 Jan 1;192:259-269
Life sciences 2018 Jan 1;192:259-269
Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway.
Shen Z, Ma Y, Ji Z, Hao Y, Yan X, Zhong Y, Tang X, Ren W
Lipids in health and disease 2018 Feb 9;17(1):26
Lipids in health and disease 2018 Feb 9;17(1):26
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Yu Z, Tian X, Peng Y, Sun Z, Wang C, Tang N, Li B, Jian Y, Wang W, Huo X, Ma X
Journal of pineal research 2018 Aug;65(1):e12478
Journal of pineal research 2018 Aug;65(1):e12478
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Meng M, Chen Y, Jia J, Li L, Yang S
Biological research 2018 Aug 10;51(1):24
Biological research 2018 Aug 10;51(1):24
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, Huang Q, Guo X, Zhang J, Ji L, Li J, Zhang H, Yang H, Xing J
Antioxidants & redox signaling 2018 Apr 20;28(12):1120-1136
Antioxidants & redox signaling 2018 Apr 20;28(12):1120-1136
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Wang Y, He T, Herman JG, Linghu E, Yang Y, Fuks F, Zhou F, Song L, Guo M
Clinical epigenetics 2017;9:115
Clinical epigenetics 2017;9:115
Human Enterovirus 68 Interferes with the Host Cell Cycle to Facilitate Viral Production.
Wang ZY, Zhong T, Wang Y, Song FM, Yu XF, Xing LP, Zhang WY, Yu JH, Hua SC, Yu XF
Frontiers in cellular and infection microbiology 2017;7:29
Frontiers in cellular and infection microbiology 2017;7:29
Salusin-β mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.
Zhu X, Zhou Y, Cai W, Sun H, Qiu L
Biochemical and biophysical research communications 2017 Sep 16;491(2):515-521
Biochemical and biophysical research communications 2017 Sep 16;491(2):515-521
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Zhang S, Yao F, Jing T, Zhang M, Zhao W, Zou X, Sui L, Hou L
Gene 2017 Sep 10;628:170-179
Gene 2017 Sep 10;628:170-179
Pseudolaric acid B inhibits neuroglioma cell proliferation through DNA damage response.
Song F, Yu X, Zhang H, Wang Z, Wang Y, Meng X, Yu J
Oncology reports 2017 Oct;38(4):2211-2218
Oncology reports 2017 Oct;38(4):2211-2218
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Shen W, Zhu S, Qin H, Zhong M, Wu J, Zhang R, Song H
Molecular medicine reports 2017 Oct;16(4):4054-4060
Molecular medicine reports 2017 Oct;16(4):4054-4060
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Zheng C, Zheng Z, Sun J, Zhang Y, Wei C, Ke X, Liu Y, Deng L, Wang H
Scientific reports 2017 Nov 27;7(1):16422
Scientific reports 2017 Nov 27;7(1):16422
(-)-Curine induces cell cycle arrest and cell death in hepatocellular carcinoma cells in a p53-independent way.
Gong S, Xu D, Zou F, Peng R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:894-901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:894-901
Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGFβ2 feedback loop.
Lei K, Liang X, Gao Y, Xu B, Xu Y, Li Y, Tao Y, Shi W, Liu J
Biochemical and biophysical research communications 2017 Mar 11;484(3):514-521
Biochemical and biophysical research communications 2017 Mar 11;484(3):514-521
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.
He T, Zhang M, Zheng R, Zheng S, Linghu E, Herman JG, Guo M
Epigenomics 2017 Jun;9(6):849-862
Epigenomics 2017 Jun;9(6):849-862
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Li J, Zhang M, He T, Li H, Cao T, Zheng L, Guo M
Scientific reports 2017 Jun 12;7(1):3325
Scientific reports 2017 Jun 12;7(1):3325
The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration.
Li C, Chang L, Chen Z, Liu Z, Wang Y, Ye Q
International journal of molecular medicine 2017 Feb;39(2):347-356
International journal of molecular medicine 2017 Feb;39(2):347-356
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, Ma H, He K, Wang Y, Han B, Ye X, Li X
Scientific reports 2017 Feb 6;7:38524
Scientific reports 2017 Feb 6;7:38524
Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.
Wang X, Li Y, Lin M, Jin J, Huang Z
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2017 Dec;30(6):903-915
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2017 Dec;30(6):903-915
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
miR-873 suppresses H9C2 cardiomyocyte proliferation by targeting GLI1.
Zhang JS, Zhao Y, Lv Y, Liu PY, Ruan JX, Sun YL, Gong TX, Wan N, Qiu GR
Gene 2017 Aug 30;626:426-432
Gene 2017 Aug 30;626:426-432
Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica.
Zhang M, Yao F, Qin T, Hou L, Zou X
Gene 2017 Apr 15;608:28-40
Gene 2017 Apr 15;608:28-40
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Zhan L, Cao H, Wang G, Lyu Y, Sun X, An J, Wu Z, Huang Q, Liu B, Xing J
Oncotarget 2016 Oct 4;7(40):65001-65011
Oncotarget 2016 Oct 4;7(40):65001-65011
Inhibition of tumor suppressor p53 preserves glycation-serum induced pancreatic beta-cell demise.
Li Y, Zhang T, Huang Q, Sun Y, Chang X, Zhang H, Zhu Y, Han X
Endocrine 2016 Nov;54(2):383-395
Endocrine 2016 Nov;54(2):383-395
PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.
Yang H, Zhao X, Zhao L, Liu L, Li J, Jia W, Liu J, Huang G
Oncotarget 2016 Nov 1;7(44):72131-72147
Oncotarget 2016 Nov 1;7(44):72131-72147
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
He Y, Tang D, Cai C, Chai R, Li H
Molecular neurobiology 2016 May;53(4):2421-34
Molecular neurobiology 2016 May;53(4):2421-34
The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.
Yin J, Sheng B, Han B, Pu A, Yang K, Li P, Wang Q, Xiao W, Yang H
Cell biology international 2016 May;40(5):560-8
Cell biology international 2016 May;40(5):560-8
Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells.
Zhang D, Li Y, Wang R, Li Y, Shi P, Kan Z, Pang X
International journal of molecular sciences 2016 May 3;17(5)
International journal of molecular sciences 2016 May 3;17(5)
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
Fei Z, Gao Y, Qiu M, Qi X, Dai Y, Wang S, Quan Z, Liu Y, Ou J
Journal of clinical biochemistry and nutrition 2016 Mar;58(2):105-13
Journal of clinical biochemistry and nutrition 2016 Mar;58(2):105-13
Carfilzomib induces G2/M cell cycle arrest in human endometrial cancer cells via upregulation of p21(Waf1/Cip1) and p27(Kip1).
Zhou Y, Wang K, Zhen S, Wang R, Luo W
Taiwanese journal of obstetrics & gynecology 2016 Dec;55(6):847-851
Taiwanese journal of obstetrics & gynecology 2016 Dec;55(6):847-851
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gao H, Sun B, Fu H, Chi X, Wang F, Qi X, Hu J, Shao S
Oncotarget 2016 Aug 16;7(33):53289-53298
Oncotarget 2016 Aug 16;7(33):53289-53298
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, Li J, Guo J, Luo S, Zheng Y
Molecular medicine reports 2016 Apr;13(4):3009-16
Molecular medicine reports 2016 Apr;13(4):3009-16
Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition.
Ye L, Guo L, He Z, Wang X, Lin C, Zhang X, Wu S, Bao Y, Yang Q, Song L, Lin H
Oncotarget 2016 Apr 26;7(17):23757-71
Oncotarget 2016 Apr 26;7(17):23757-71
Down-regulation of cancer/testis antigen OY-TES-1 attenuates malignant behaviors of hepatocellular carcinoma cells in vitro.
Fu J, Luo B, Guo WW, Zhang QM, Shi L, Hu QP, Chen F, Xiao SW, Xie XX
International journal of clinical and experimental pathology 2015;8(7):7786-97
International journal of clinical and experimental pathology 2015;8(7):7786-97
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Dai B, Wang W, Liu R, Wang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
Shan X, Fu YS, Aziz F, Wang XQ, Yan Q, Liu JW
PloS one 2014;9(12):e115401
PloS one 2014;9(12):e115401
Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice.
Dai B, Zhan Y, Qi J, Zhang Y
Environmental toxicology and pharmacology 2014 May;37(3):1177-85
Environmental toxicology and pharmacology 2014 May;37(3):1177-85
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Zhang Y, Zhan Y, Zhang D, Dai B, Ma W, Qi J, Liu R, He L
Scientific reports 2014 Jul 1;4:5518
Scientific reports 2014 Jul 1;4:5518
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Sun Q, Wang R, Wang Y, Luo J, Wang P, Cheng B
Oncology reports 2014 Feb;31(2):933-9
Oncology reports 2014 Feb;31(2):933-9
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Song Y, Gong K, Yan H, Hong W, Wang L, Wu Y, Li W, Li W, Cao Z
The Journal of biological chemistry 2014 Apr 25;289(17):11667-11680
The Journal of biological chemistry 2014 Apr 25;289(17):11667-11680
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.
Furuta M, Kozaki K, Tanimoto K, Tanaka S, Arii S, Shimamura T, Niida A, Miyano S, Inazawa J
PloS one 2013;8(3):e60155
PloS one 2013;8(3):e60155
C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis.
Hu HM, Chen Y, Liu L, Zhang CG, Wang W, Gong K, Huang Z, Guo MX, Li WX, Li W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jan;27(1):163-73
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jan;27(1):163-73
Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells.
Zheng L, Wang X, Luo W, Zhan Y, Zhang Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Aug;58:332-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Aug;58:332-9
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.
Gong K, Xie J, Yi H, Li W
The Biochemical journal 2012 May 1;443(3):735-46
The Biochemical journal 2012 May 1;443(3):735-46
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cyclin E antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cyclin E. This antibody recognizes human,mouse,rat antigen. The Cyclin E antibody has been validated for the following applications: ELISA, WB analysis.
