Tissue expression
Cell line expression
Protein structure
SPA17
Sperm autoantigenic protein 17CT22, SP17
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22. [provided by RefSeq, Jan 2009]
Top validated antibodies |
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Proteintech Group | 13367-1-AP | 5 references | Polyclonal |
WB
EL
IP
IHC |
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Novus Biologicals | H00053340-B01P | 2 references | Polyclonal |
WB
ICC
IHC
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Atlas Antibodies | HPA037568 | Polyclonal |
WB
ICC
IHC
|
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Invitrogen Antibodies | 13367-1-AP | Polyclonal |
WB
IP
IHC
OA |
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NovoPro Bioscience Inc. | 115526 | Polyclonal |
WB
EL
IP
IHC |
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Supportive data in Antibodypedia
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Recommended by provider