NB100-63307

antibody from Novus Biologicals

Targeting: ANXA5 ANX5, ENX2

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NB100-63307

Provider

Novus Biologicals

Proper citation

Novus Cat#NB100-63307, RRID:AB_959129

Product name

Mouse Monoclonal Annexin V Antibody

Antibody type

Monoclonal

Description

Protein G purified. NB100-64303 specifically recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Clone VAA-33 has been reported to work in western blotting applications.

Reactivity

Human

Host

Mouse

Conjugate

Green dye

Isotype

IgG

Vial size

0.05 ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.