Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [4]
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- Product number
- NBP2-27561 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal ENPP-1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Rat, Chicken/Avian
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models.
Central role of pyrophosphate in acellular cementum formation.
Metabolic consequences of ENPP1 overexpression in adipose tissue.
The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.
Extracellular nucleotides block bone mineralization in vitro: evidence for dual inhibitory mechanisms involving both P2Y2 receptors and pyrophosphate.
Role of ENPP1 on adipocyte maturation.
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
Takeda TA, Miyazaki S, Kobayashi M, Nishino K, Goto T, Matsunaga M, Ooi M, Shirakawa H, Tani F, Kawamura T, Komai M, Kambe T
Communications biology 2018;1:113
Communications biology 2018;1:113
Central role of pyrophosphate in acellular cementum formation.
Foster BL, Nagatomo KJ, Nociti FH Jr, Fong H, Dunn D, Tran AB, Wang W, Narisawa S, Millán JL, Somerman MJ
PloS one 2012;7(6):e38393
PloS one 2012;7(6):e38393
Metabolic consequences of ENPP1 overexpression in adipose tissue.
Pan W, Ciociola E, Saraf M, Tumurbaatar B, Tuvdendorj D, Prasad S, Chandalia M, Abate N
American journal of physiology. Endocrinology and metabolism 2011 Nov;301(5):E901-11
American journal of physiology. Endocrinology and metabolism 2011 Nov;301(5):E901-11
The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.
Lim J, Zhou M, Veenstra TD, Morrison DK
Genes & development 2010 Jul 15;24(14):1496-506
Genes & development 2010 Jul 15;24(14):1496-506
Extracellular nucleotides block bone mineralization in vitro: evidence for dual inhibitory mechanisms involving both P2Y2 receptors and pyrophosphate.
Orriss IR, Utting JC, Brandao-Burch A, Colston K, Grubb BR, Burnstock G, Arnett TR
Endocrinology 2007 Sep;148(9):4208-16
Endocrinology 2007 Sep;148(9):4208-16
Role of ENPP1 on adipocyte maturation.
Liang J, Fu M, Ciociola E, Chandalia M, Abate N
PloS one 2007 Sep 12;2(9):e882
PloS one 2007 Sep 12;2(9):e882
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
Meyre D, Bouatia-Naji N, Tounian A, Samson C, Lecoeur C, Vatin V, Ghoussaini M, Wachter C, Hercberg S, Charpentier G, Patsch W, Pattou F, Charles MA, Tounian P, Clément K, Jouret B, Weill J, Maddux BA, Goldfine ID, Walley A, Boutin P, Dina C, Froguel P
Nature genetics 2005 Aug;37(8):863-7
Nature genetics 2005 Aug;37(8):863-7
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - Human Liver. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - Staining of paraffin embedded Human Liver. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - Staining of paraffin embedded Human Thyroid Gland at dilution of 8ug/ml. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - Negative Control showing staining of paraffin embedded Human Thyroid Gland, with no primary antibody.