Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB6879 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB6879, RRID:AB_1574682
- Product name
- ENPP1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Goat polyclonal antibody raised against synthetic peptide of ENPP1.
- Antigen sequence
C-KTHLPTFSQED
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
Bertrand J, Nitschke Y, Fuerst M, Hermann S, Schäfers M, Sherwood J, Nalesso G, Ruether W, Rutsch F, Dell'Accio F, Pap T
Annals of the rheumatic diseases 2012 Jul;71(7):1249-53
Annals of the rheumatic diseases 2012 Jul;71(7):1249-53
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
Meyre D, Bouatia-Naji N, Tounian A, Samson C, Lecoeur C, Vatin V, Ghoussaini M, Wachter C, Hercberg S, Charpentier G, Patsch W, Pattou F, Charles MA, Tounian P, Clément K, Jouret B, Weill J, Maddux BA, Goldfine ID, Walley A, Boutin P, Dina C, Froguel P
Nature genetics 2005 Aug;37(8):863-7
Nature genetics 2005 Aug;37(8):863-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- HEK293 overexpressing Human ENPP1 and probed with ENPP1 polyclonal antibody (Cat # PAB6879) (mock transfection in first lane) .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- ENPP1 polyclonal antibody (Cat # PAB6879) (1 ug/mL) staining of paraffin embedded human liver. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)