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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN350134 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350134, RRID:AB_10781418
- Product name
- anti-Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) (AA 1000-1050) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from aa region 1000-1050 of human CACNA1A conjugated to blue carrier protein was used as the antigen. The antigen shares 87% identity with mouse and rat sequence.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 1000-1050
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Clusters of non-truncating mutations of P/Q type Ca2+ channel subunit Ca(v)2.1 causing episodic ataxia 2.
The clinical spectrum of familial hemiplegic migraine associated with mutations in a neuronal calcium channel.
Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels.
Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4.
Expression and antibody inhibition of P-type calcium channels in human small-cell lung carcinoma cells.
Mantuano E, Veneziano L, Spadaro M, Giunti P, Guida S, Leggio MG, Verriello L, Wood N, Jodice C, Frontali M
Journal of medical genetics 2004 Jun;41(6):e82
Journal of medical genetics 2004 Jun;41(6):e82
The clinical spectrum of familial hemiplegic migraine associated with mutations in a neuronal calcium channel.
Ducros A, Denier C, Joutel A, Cecillon M, Lescoat C, Vahedi K, Darcel F, Vicaut E, Bousser MG, Tournier-Lasserve E
The New England journal of medicine 2001 Jul 5;345(1):17-24
The New England journal of medicine 2001 Jul 5;345(1):17-24
Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels.
Hans M, Urrutia A, Deal C, Brust PF, Stauderman K, Ellis SB, Harpold MM, Johnson EC, Williams ME
Biophysical journal 1999 Mar;76(3):1384-400
Biophysical journal 1999 Mar;76(3):1384-400
Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4.
Ophoff RA, Terwindt GM, Vergouwe MN, van Eijk R, Oefner PJ, Hoffman SM, Lamerdin JE, Mohrenweiser HW, Bulman DE, Ferrari M, Haan J, Lindhout D, van Ommen GJ, Hofker MH, Ferrari MD, Frants RR
Cell 1996 Nov 1;87(3):543-52
Cell 1996 Nov 1;87(3):543-52
Expression and antibody inhibition of P-type calcium channels in human small-cell lung carcinoma cells.
Barry EL, Viglione MP, Kim YI, Froehner SC
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 Jan;15(1 Pt 1):274-83
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 Jan;15(1 Pt 1):274-83
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