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- Product number
- H00010797-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00010797-M01, RRID:AB_540619
- Product name
- Mouse Monoclonal MTHFD2 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. MTHFD2 - methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
Gustafsson Sheppard N, Jarl L, Mahadessian D, Strittmatter L, Schmidt A, Madhusudan N, Tegnér J, Lundberg EK, Asplund A, Jain M, Nilsson R
Scientific reports 2015 Oct 13;5:15029
Scientific reports 2015 Oct 13;5:15029
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
Nilsson R, Jain M, Madhusudhan N, Sheppard NG, Strittmatter L, Kampf C, Huang J, Asplund A, Mootha VK
Nature communications 2014;5:3128
Nature communications 2014;5:3128
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: MTHFD2 Antibody (4G7-2G3) [H00010797-M01] - Analysis of MTHFD2 expression in transfected 293T cell line by MTHFD2 monoclonal antibody (M01), clone 4G7-2G3.Lane 1: MTHFD2 transfected lysate(26.8 KDa).Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: MTHFD2 Antibody (4G7-2G3) [H00010797-M01] - MTHFD2 monoclonal antibody (M01), clone 4G7-2G3 Analysis of MTHFD2 expression in HepG2.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MTHFD2 Antibody (4G7-2G3) [H00010797-M01] - Analysis of monoclonal antibody to MTHFD2 on formalin-fixed paraffin-embedded human lymphoma tissue. Antibody concentration 3 ug/ml.
