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- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 21745-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21745-1-AP, RRID:AB_10734328
- Product name
- VNN1 antibody
- Antibody type
- Polyclonal
- Description
- VNN1 antibody (Cat. #21745-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Brown adipose Vanin-1 is required for the maintenance of mitochondrial homeostasis and prevents diet-induced metabolic dysfunction.
Effects of ABCG1 knockout on proteomic composition of HDL in mice on a chow diet and a high-fat diet.
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Ductal Cell Damage by Inhibiting the S100A9/VNN1 Signaling Pathway.
Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway.
Novel Elements of the Chondrocyte Stress Response Identified Using an in Vitro Model of Mouse Cartilage Degradation.
VNN1 promotes atherosclerosis progression in apoE-/- mice fed a high-fat/high-cholesterol diet.
Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease.
Vanin-1 is a key activator for hepatic gluconeogenesis.
Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells.
Sun C, Liang J, Zheng J, Mao S, Chen S, Aikemu A, Liu C
Molecular metabolism 2024 Feb;80:101884
Molecular metabolism 2024 Feb;80:101884
Effects of ABCG1 knockout on proteomic composition of HDL in mice on a chow diet and a high-fat diet.
Wu Y, Chen L, Xie Z, Wang C, Zhang J, Yan X
Proteomics 2022 May;22(10):e2100028
Proteomics 2022 May;22(10):e2100028
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Ductal Cell Damage by Inhibiting the S100A9/VNN1 Signaling Pathway.
Guo F, Zhou Q, Wu Y, Chen M, Zhao L, Xiang H
Pancreas 2022 Aug 1;51(7):739-746
Pancreas 2022 Aug 1;51(7):739-746
Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation.
Xiang H, Guo F, Tao X, Zhou Q, Xia S, Deng D, Li L, Shang D
Theranostics 2021;11(9):4467-4482
Theranostics 2021;11(9):4467-4482
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway.
Chen X, Bian M, Zhang C, Kai J, Yao Z, Jin H, Lu C, Shao J, Chen A, Zhang F, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:975-984
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:975-984
Novel Elements of the Chondrocyte Stress Response Identified Using an in Vitro Model of Mouse Cartilage Degradation.
Wilson R, Golub SB, Rowley L, Angelucci C, Karpievitch YV, Bateman JF, Fosang AJ
Journal of proteome research 2016 Mar 4;15(3):1033-50
Journal of proteome research 2016 Mar 4;15(3):1033-50
VNN1 promotes atherosclerosis progression in apoE-/- mice fed a high-fat/high-cholesterol diet.
Hu YW, Wu SG, Zhao JJ, Ma X, Lu JB, Xiu JC, Zhang Y, Huang C, Qiu YR, Sha YH, Gao JJ, Wang YC, Li SF, Zhao JY, Zheng L, Wang Q
Journal of lipid research 2016 Aug;57(8):1398-411
Journal of lipid research 2016 Aug;57(8):1398-411
Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease.
Povero D, Eguchi A, Li H, Johnson CD, Papouchado BG, Wree A, Messer K, Feldstein AE
PloS one 2014;9(12):e113651
PloS one 2014;9(12):e113651
Vanin-1 is a key activator for hepatic gluconeogenesis.
Chen S, Zhang W, Tang C, Tang X, Liu L, Liu C
Diabetes 2014 Jun;63(6):2073-85
Diabetes 2014 Jun;63(6):2073-85
Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells.
Povero D, Eguchi A, Niesman IR, Andronikou N, de Mollerat du Jeu X, Mulya A, Berk M, Lazic M, Thapaliya S, Parola M, Patel HH, Feldstein AE
Science signaling 2013 Oct 8;6(296):ra88
Science signaling 2013 Oct 8;6(296):ra88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 21745-1-AP(VNN1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VNN1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human VNN1. This antibody recognizes human,mouse,rat antigen. The VNN1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
