Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350690 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350690, RRID:AB_10781662
- Product name
- anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (C-Term), (AA 100-170) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from c-terminal region (aa 100-170) of human p27 Kip1 (KIP1, p27Kip1) conjugated to an immunogenic carrier protein was used as the immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term,AA 100-170
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases.
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias.
Grimmler M, Wang Y, Mund T, Cilensek Z, Keidel EM, Waddell MB, Jäkel H, Kullmann M, Kriwacki RW, Hengst L
Cell 2007 Jan 26;128(2):269-80
Cell 2007 Jan 26;128(2):269-80
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D, Vinci F, Chiappetta G, Tsichlis P, Bellacosa A, Fusco A, Santoro M
Nature medicine 2002 Oct;8(10):1136-44
Nature medicine 2002 Oct;8(10):1136-44
Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias.
Pietenpol JA, Bohlander SK, Sato Y, Papadopoulos N, Liu B, Friedman C, Trask BJ, Roberts JM, Kinzler KW, Rowley JD
Cancer research 1995 Mar 15;55(6):1206-10
Cancer research 1995 Mar 15;55(6):1206-10
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