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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN358186 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (pThr187) antibody
- Antibody type
- Polyclonal
- Description
- Protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pThr187
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Methylation status analysis of cell cycle regulatory genes (p16INK4A, p15INK4B, p21Waf1/Cip1, p27Kip1 and p73) in natural killer cell disorders.
Current approaches to unravel the mystery of dilated cardiomyopathy, a common cause of hereditary heart failure.
BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells.
The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27.
Activation of p27Kip1 Expression by E2F1. A negative feedback mechanism.
Kawamata N, Inagaki N, Mizumura S, Sugimoto KJ, Sakajiri S, Ohyanagi-Hara M, Oshimi K
European journal of haematology 2005 May;74(5):424-9
European journal of haematology 2005 May;74(5):424-9
Current approaches to unravel the mystery of dilated cardiomyopathy, a common cause of hereditary heart failure.
Mogensen J, Shaw T
Expert review of proteomics 2005 Dec;2(6):827-30
Expert review of proteomics 2005 Dec;2(6):827-30
BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells.
Andreu EJ, Lledó E, Poch E, Ivorra C, Albero MP, Martínez-Climent JA, Montiel-Duarte C, Rifón J, Pérez-Calvo J, Arbona C, Prósper F, Pérez-Roger I
Cancer research 2005 Apr 15;65(8):3264-72
Cancer research 2005 Apr 15;65(8):3264-72
The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27.
Wingate H, Zhang N, McGarhen MJ, Bedrosian I, Harper JW, Keyomarsi K
The Journal of biological chemistry 2005 Apr 15;280(15):15148-57
The Journal of biological chemistry 2005 Apr 15;280(15):15148-57
Activation of p27Kip1 Expression by E2F1. A negative feedback mechanism.
Wang C, Hou X, Mohapatra S, Ma Y, Cress WD, Pledger WJ, Chen J
The Journal of biological chemistry 2005 Apr 1;280(13):12339-43
The Journal of biological chemistry 2005 Apr 1;280(13):12339-43
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