orb1951759

antibody from Biorbyt
Targeting: CDKN1B KIP1, P27KIP1
Provider product page for orb1951759
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb1951759 - Provider product page
Provider
Biorbyt
Product name
p27 KIP 1 Rabbit mAb [KD Validated]
Antibody type
Recombinant
Description
The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Reactivity
Human, Rat
Host
Rabbit
Conjugate
Unconjugated
Vial size
50 ul
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
CDKN1B protein structure - orb1951759 shown in red.