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- Antigen structure
- References [24]
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- Product number
- 14040-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14040-1-AP, RRID:AB_10640426
- Product name
- ACRV1 antibody
- Antibody type
- Polyclonal
- Description
- ACRV1 antibody (Cat. #14040-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ELAPOR1 mediated vesicle traffic is required for acrosome biogenesis and male fertility in mice.
Nighttime-restricted feeding disrupts spermatogenesis in mice via gut microbiota-derived KYNA homeostasis.
Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1.
Tdrd15 is dispensable for male fertility and spermatogenesis in the golden hamster.
PIWI proteins tether the piRNA biogenesis machinery to mitochondria during mammalian spermatogenesis.
Spatiotemporal control of PIWI compartmentalization by mitochondrial scaffolds defines pachytene piRNA pathway organization.
Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice.
Screening and Evaluation of Male Reproductive Effects of Isothiazolinones at Human-Relevant Levels in Mammals: Direct Impairments and Increased Susceptibility to Subsequent Spermatogenic Stress.
Application of Inertial Microfluidics for Isolation and Removal of Round Spermatids from a Spermatogenic Cell Sample to Assist In-Vitro Human Spermatogenesis.
piRNA loading triggers MIWI translocation from the intermitochondrial cement to chromatoid body during mouse spermatogenesis.
Autophagy core protein BECN1 is vital for spermatogenesis and male fertility in mice†.
Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice.
LanCL2 Implicates in Testicular Redox Homeostasis and Acrosomal Maturation.
WNK1 is required during male pachynema to sustain fertility.
Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) impairs Postnatal Testis Development in Mice: The Microtubule Cytoskeleton as a Sensitive Target.
Extended exposure to tetrabromobisphenol A-bis(2,3-dibromopropyl ether) leads to subfertility in male mice at the late reproductive age.
MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing.
SYPL1 defines a vesicular pathway essential for sperm cytoplasmic droplet formation and male fertility.
SATINN: an automated neural network-based classification of testicular sections allows for high-throughput histopathology of mouse mutants.
Recellularized rat testis scaffolds with embryoid bodies cells: a promising approach for tissue engineering.
BAF-L Modulates Histone-to-Protamine Transition during Spermiogenesis.
ARHGEF15 in Sertoli cells contributes to germ cell development and testicular immune privilege†.
Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis.
TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice.
Ding R, Guo Q, Wang L, Tang N, Fang X, Xin Z, Zhao W, Liu Y
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 6;83(1)
Nighttime-restricted feeding disrupts spermatogenesis in mice via gut microbiota-derived KYNA homeostasis.
Yang D, Xie D, Li C, Liu Y, Cheng X, Liu J, Lu Q, Jia L, Liu W, Luo Q, Chen Z, Huang C
Communications biology 2026 Feb 3;9(1)
Communications biology 2026 Feb 3;9(1)
Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1.
Tanis S, Simon LE, Alexander AK, Horan TS, Carro MLM, Bonnett SJ, Xie A, Ben-Shlomo R, Owens CE, Danko CG, Lujic J, Cohen PE
Proceedings of the National Academy of Sciences of the United States of America 2026 Apr 14;123(15):e2517498123
Proceedings of the National Academy of Sciences of the United States of America 2026 Apr 14;123(15):e2517498123
Tdrd15 is dispensable for male fertility and spermatogenesis in the golden hamster.
Zhu M, Xiang Y, Wang H, Zhao S, Zeng W, Li J, Yao B
European journal of medical research 2025 Oct 22;30(1):1013
European journal of medical research 2025 Oct 22;30(1):1013
PIWI proteins tether the piRNA biogenesis machinery to mitochondria during mammalian spermatogenesis.
Gao J, Chen C, Shang G, Yu W, Zhao T, Zhang Y, Chen C, Ding D
The EMBO journal 2025 Nov;44(22):6397-6424
The EMBO journal 2025 Nov;44(22):6397-6424
Spatiotemporal control of PIWI compartmentalization by mitochondrial scaffolds defines pachytene piRNA pathway organization.
Yan X, Wei C, Mann JM, Shang G, Wang Q, Xie H, Demireva EY, Sun L, Ding D, Chen C
bioRxiv : the preprint server for biology 2025 Nov 4;
bioRxiv : the preprint server for biology 2025 Nov 4;
Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice.
Zhou Y, Tu C, Coutton C, Tang J, Tian S, Tang S, Martinez G, Zhou D, Tebbakh C, Wang J, Zouari R, Zhou X, Ben Mustapha SF, Wang X, Wu B, Geng X, Liu S, Jin L, Shi H, Tan YQ, Ray PF, Wang L, Yang X, Zhang F, Liu C
Science China. Life sciences 2025 Mar;68(3):777-792
Science China. Life sciences 2025 Mar;68(3):777-792
Screening and Evaluation of Male Reproductive Effects of Isothiazolinones at Human-Relevant Levels in Mammals: Direct Impairments and Increased Susceptibility to Subsequent Spermatogenic Stress.
Xiong YM, Chen XY, Wang HZ, Li XH, Li YY, Qin ZF
Environmental science & technology 2025 Jun 10;59(22):10812-10825
Environmental science & technology 2025 Jun 10;59(22):10812-10825
Application of Inertial Microfluidics for Isolation and Removal of Round Spermatids from a Spermatogenic Cell Sample to Assist In-Vitro Human Spermatogenesis.
Nepal S, Casalini J, Jafek A, Gale B
Micromachines 2025 Apr 25;16(5)
Micromachines 2025 Apr 25;16(5)
piRNA loading triggers MIWI translocation from the intermitochondrial cement to chromatoid body during mouse spermatogenesis.
Wei H, Gao J, Lin DH, Geng R, Liao J, Huang TY, Shang G, Jing J, Fan ZW, Pan D, Yin ZQ, Li T, Liu X, Zhao S, Chen C, Li J, Wang X, Ding D, Liu MF
Nature communications 2024 Mar 15;15(1):2343
Nature communications 2024 Mar 15;15(1):2343
Autophagy core protein BECN1 is vital for spermatogenesis and male fertility in mice†.
Ke L, Lin X, Luo Y, Tao S, Yan C, He Y, Wu Y, Liu N, Qin Y
Biology of reproduction 2024 Mar 13;110(3):599-614
Biology of reproduction 2024 Mar 13;110(3):599-614
Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice.
Lima AC, Okhovat M, Stendahl AM, VanCampen J, Nevonen KA, Herrera J, Li W, Harshman L, Yang R, Fedorov LM, Vigh-Conrad KA, Ahituv N, Conrad DF, Carbone L
bioRxiv : the preprint server for biology 2024 Jul 10;
bioRxiv : the preprint server for biology 2024 Jul 10;
LanCL2 Implicates in Testicular Redox Homeostasis and Acrosomal Maturation.
Zhao Y, Wang J, Shi S, Lan X, Cheng X, Li L, Zou Y, Jia L, Liu W, Luo Q, Chen Z, Huang C
Antioxidants (Basel, Switzerland) 2024 Apr 27;13(5)
Antioxidants (Basel, Switzerland) 2024 Apr 27;13(5)
WNK1 is required during male pachynema to sustain fertility.
Chi RA, Xu X, Li JL, Xu X, Hu G, Brown P, Willson C, Kirsanov O, Geyer C, Huang CL, Morgan M, DeMayo F
iScience 2023 Sep 15;26(9):107616
iScience 2023 Sep 15;26(9):107616
Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) impairs Postnatal Testis Development in Mice: The Microtubule Cytoskeleton as a Sensitive Target.
Li YY, Xiong YM, Zhang SY, Deng JL, Xue Q, Hou XW, Liu WB, Li XH, Qin ZF
Environment & health (Washington, D.C.) 2023 Sep 15;1(3):168-179
Environment & health (Washington, D.C.) 2023 Sep 15;1(3):168-179
Extended exposure to tetrabromobisphenol A-bis(2,3-dibromopropyl ether) leads to subfertility in male mice at the late reproductive age.
Li YY, Xiong YM, Chen XY, Sheng JY, Lv L, Li XH, Qin ZF
Archives of toxicology 2023 Nov;97(11):2983-2995
Archives of toxicology 2023 Nov;97(11):2983-2995
MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing.
Wei C, Jing J, Yan X, Mann JM, Geng R, Xie H, Demireva EY, Hess RA, Ding D, Chen C
PLoS genetics 2023 Nov;19(11):e1011031
PLoS genetics 2023 Nov;19(11):e1011031
SYPL1 defines a vesicular pathway essential for sperm cytoplasmic droplet formation and male fertility.
Liu J, Hermo L, Ding D, Wei C, Mann JM, Yan X, Melnick AF, Wu Y, Withrow A, Cibelli J, Hess RA, Chen C
Nature communications 2023 Aug 22;14(1):5113
Nature communications 2023 Aug 22;14(1):5113
SATINN: an automated neural network-based classification of testicular sections allows for high-throughput histopathology of mouse mutants.
Yang R, Stendahl AM, Vigh-Conrad KA, Held M, Lima AC, Conrad DF
Bioinformatics (Oxford, England) 2022 Nov 30;38(23):5288-5298
Bioinformatics (Oxford, England) 2022 Nov 30;38(23):5288-5298
Recellularized rat testis scaffolds with embryoid bodies cells: a promising approach for tissue engineering.
Batista VF, de Sá Schiavo Matias G, Carreira ACO, Smith LC, Rodrigues R, Araujo MS, Souza Silva DR, Moraes FJ, Garcia JM, Miglino MA
Systems biology in reproductive medicine 2022 Feb;68(1):44-54
Systems biology in reproductive medicine 2022 Feb;68(1):44-54
BAF-L Modulates Histone-to-Protamine Transition during Spermiogenesis.
Huang C, Gong H, Mu B, Lan X, Yang C, Tan J, Liu W, Zou Y, Li L, Feng B, He X, Luo Q, Chen Z
International journal of molecular sciences 2022 Feb 11;23(4)
International journal of molecular sciences 2022 Feb 11;23(4)
ARHGEF15 in Sertoli cells contributes to germ cell development and testicular immune privilege†.
Chen F, Wu Y, Ke L, Lin X, Wang F, Qin Y
Biology of reproduction 2022 Dec 10;107(6):1565-1579
Biology of reproduction 2022 Dec 10;107(6):1565-1579
Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis.
Ding D, Liu J, Dong K, Melnick AF, Latham KE, Chen C
Nucleic acids research 2019 Mar 18;47(5):2594-2608
Nucleic acids research 2019 Mar 18;47(5):2594-2608
TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice.
Ding D, Liu J, Midic U, Wu Y, Dong K, Melnick A, Latham KE, Chen C
Nature communications 2018 Jan 9;9(1):127
Nature communications 2018 Jan 9;9(1):127
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACRV1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACRV1. This antibody recognizes human antigen. The ACRV1 antibody has been validated for the following applications: ELISA, WB analysis.
