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- References [9]
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- Product number
- 22045-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22045-1-AP, RRID:AB_11182927
- Product name
- AHI1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AHI1 antibody (Cat. #22045-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sub-ciliary localization of CEP290 and effects of its loss in mouse photoreceptors during development.
The Multifaceted Role of EXOC6A in Ciliogenesis.
Proximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins.
Ciliopathy-associated protein, CEP290, is required for ciliary necklace and outer segment membrane formation in retinal photoreceptors.
EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO.
Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone.
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling.
Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.
Moye AR, Robichaux MA, Agosto MA, Moulin AP, Graff-Meyer A, Rivolta C, Wensel TG
Journal of cell science 2025 Oct 15;138(20)
Journal of cell science 2025 Oct 15;138(20)
The Multifaceted Role of EXOC6A in Ciliogenesis.
Lin TL, Wu CT, Tang TK
bioRxiv : the preprint server for biology 2025 Jul 25;
bioRxiv : the preprint server for biology 2025 Jul 25;
Proximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins.
Yoshioka K, Nakagawa R, Nguyen CLK, Suzuki H, Ishigaki K, Mizuno S, Okiyoneda T, Ebihara S, Murata K
FEBS open bio 2025 Jan;15(1):151-164
FEBS open bio 2025 Jan;15(1):151-164
Ciliopathy-associated protein, CEP290, is required for ciliary necklace and outer segment membrane formation in retinal photoreceptors.
Moye AR, Robichaux MA, Agosto MA, Rivolta C, Moulin AP, Wensel TG
bioRxiv : the preprint server for biology 2025 Jan 20;
bioRxiv : the preprint server for biology 2025 Jan 20;
EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO.
Barbeito P, Martin-Morales R, Palencia-Campos A, Cerrolaza J, Rivas-Santos C, Gallego-Colastra L, Caparros-Martin JA, Martin-Bravo C, Martin-Hurtado A, Sánchez-Bellver L, Marfany G, Ruiz-Perez VL, Garcia-Gonzalo FR
Frontiers in cell and developmental biology 2023;11:1190258
Frontiers in cell and developmental biology 2023;11:1190258
Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone.
Conduit SE, Davies EM, Fulcher AJ, Oorschot V, Mitchell CA
Frontiers in cell and developmental biology 2021;9:634649
Frontiers in cell and developmental biology 2021;9:634649
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
Molinari E, Ramsbottom SA, Srivastava S, Booth P, Alkanderi S, McLafferty SM, Devlin LA, White K, Gunay-Aygun M, Miles CG, Sayer JA
Scientific reports 2019 Jul 25;9(1):10828
Scientific reports 2019 Jul 25;9(1):10828
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling.
Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S
Cell reports 2019 Aug 13;28(7):1907-1922.e6
Cell reports 2019 Aug 13;28(7):1907-1922.e6
Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.
Lee YL, Santé J, Comerci CJ, Cyge B, Menezes LF, Li FQ, Germino GG, Moerner WE, Takemaru K, Stearns T
Molecular biology of the cell 2014 Oct 1;25(19):2919-33
Molecular biology of the cell 2014 Oct 1;25(19):2919-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AHI1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human AHI1. This antibody recognizes human antigen. The AHI1 antibody has been validated for the following applications: ELISA, WB analysis.
