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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN499916 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Glycoprotein VI (Platelet) (GP6) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- GPVI antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human GPVI. (AP30378CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2.
Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens.
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors.
Inoue O, Suzuki-Inoue K, Dean WL, Frampton J, Watson SP
The Journal of cell biology 2003 Mar 3;160(5):769-80
The Journal of cell biology 2003 Mar 3;160(5):769-80
Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens.
Jarvis GE, Atkinson BT, Snell DC, Watson SP
British journal of pharmacology 2002 Sep;137(1):107-17
British journal of pharmacology 2002 Sep;137(1):107-17
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
Jandrot-Perrus M, Busfield S, Lagrue AH, Xiong X, Debili N, Chickering T, Le Couedic JP, Goodearl A, Dussault B, Fraser C, Vainchenker W, Villeval JL
Blood 2000 Sep 1;96(5):1798-807
Blood 2000 Sep 1;96(5):1798-807
The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors.
Clemetson JM, Polgar J, Magnenat E, Wells TN, Clemetson KJ
The Journal of biological chemistry 1999 Oct 8;274(41):29019-24
The Journal of biological chemistry 1999 Oct 8;274(41):29019-24
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of GPVI in A20 lysate with AP30378PU-N GPVI antibody at 1?g/ml in either the absence or (B) the presence of blocking peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of GPVI in human heart tissue with AP30378PU-N GPVI antibody at 10 ?g/ml.
