Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- HPA039632 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA039632, RRID:AB_10794200
- Product name
- Anti-DCPS
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human DCPS, Gene description: decapping enzyme, scavenger, Alternative Gene Names: HINT-5, HSL1, HSPC015, Validated applications: WB, IHC, ICC, Uniprot ID: Q96C86, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels
Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects
Blum R, Cherry J, DiDonato C, Androphy E, Calo A, Potter K, Custer S, Du S, Foley T, Gopalsamy A, Reedich E, Gordo S, Gordon W, Hosea N, Jones L, Krizay D, LaRosa G, Li H, Mathur S, Menard C, Patel P, Ramos-Zayas R, Rietz A, Rong H, Zhang B, Tones M
PLOS ONE 2017;12(9):e0185079
PLOS ONE 2017;12(9):e0185079
Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects
Ng C, Shboul M, Taverniti V, Bonnard C, Lee H, Eskin A, Nelson S, Al-Raqad M, Altawalbeh S, Séraphin B, Reversade B
Human Molecular Genetics 2015;24(11):3163-3171
Human Molecular Genetics 2015;24(11):3163-3171
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in EFO-21 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-DCPS antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
- Sample type
- Human