MAP7

The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Description

Microtubule associated protein 7

Tissue specificity

Tissue enhanced (brain)

Subcell location

Microtubules, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (136342281 - 136550819)

Ensembl ID

ENSG00000135525  (ver. 103.38)

Orthologs

Mouse Map7: ENSMUSG00000019996

UniProt

Q14244

neXtProt

NX_Q14244

Human splice variants
Mouse splice variants

Protein structure