17390-1-AP

antibody from Proteintech Group

Targeting: ALDH1L1 10-fTHF, FDH, FTHFD

Provider product page for 17390-1-AP

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ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
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Product number: 17390-1-AP - Provider product page
Provider: Proteintech Group
Product name: ALDH1L1 antibody
Antibody type: Polyclonal
Description: ALDH1L1 antibody (Cat. #17390-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ALDH1L1 protein structure - 17390-1-AP shown in red.

Submitted references Astrocytic H3 receptors regulate anxiety through GABA signaling.

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Neuron 2026 Mar 5;

Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling.

Dai L, Cheng G, Cui T, He S, Wang R, Kang J, Li P, Zhang X, Ding X, Xue X, Yang L, Zhang Y, Yan Y
Cell reports 2026 Feb 24;45(2):116913

Microglia regulate neuronal activity via structural remodeling of astrocytes.

Gu N, Makashova O, Laporte C, Chen CQ, Li B, Chevillard PM, Lean G, Yang J, Wong C, Fan J, Sharif B, Saud SP, Hubacek M, Choe KY, McCarthy MM, Khoutorsky A, Bourque CW, Prager-Khoutorsky M
Neuron 2025 Oct 15;113(20):3408-3423.e5

Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat via enhancement of METTL14-mediated m6A methylation of Aldh1l1.

Wu L, Luo Z, Luo F, Huang T, Cen Y, Rao G, Zhao Z, Ou R, Zhou M
Free radical research 2025 Mar;59(3):274-288

SEC62-dependent ER-phagy contributes to apelin-13/APJ-induced monocyte-vascular endothelial cell adhesion in atherosclerosis pathogenesis.

Chen Z, Cheng J, Zhou Q, Wu LL, Chen JW, Duan XN, Yan JL, Cao JG, Xia XD, Li LF, Chen LX
Acta pharmacologica Sinica 2025 Jun;46(6):1652-1663

Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway.

Cui F, Deng S, Fu Y, Xu T, Bao S, Wang S, Lin Y, Wang X, Zhao F, Zhang T, Xu S, Zhang Z, Li W, Yang GY, Tang H, Wang J, Sheng X, Tang Y
Cell reports 2025 Jan 28;44(1):115126

Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis.

Zhang M, Lv H, Bai X, Ruan G, Li Q, Lin K, Yang H, Qian J
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VAMP4 in hypoxic adipose stem cell exosomes alleviates ischemia-reperfusion injury.

Wang Y, Yu S, Wang X, Jin R, Liu F, Yang J
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Promoting astrocyte-neuron triiodothyronine shuttling attenuates brain damage in neonatal hypoxic-ischemic encephalopathy.

Yu G, Yang Y, Zhou W, Wang X, Feng Y, Wang X, Lin Z
Journal of neuroinflammation 2025 Dec 2;23(1):5

Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners.

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Integrated machine learning and bioinformatic analysis of mitochondrial-related signature in chronic rhinosinusitis with nasal polyps.

Yang B, Gu M, Hong C, Zou XY, Zhang JQ, Yuan Y, Qiu CY, Lu MP, Cheng L
The World Allergy Organization journal 2024 Oct;17(10):100964

Defective thyroid hormone transport to the brain leads to astroglial alterations.

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Neurobiology of disease 2024 Oct 1;200:106621

Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb.

Rahimian R, Perlman K, Fakhfouri G, Mpai R, Richard VR, Hercher C, Penney L, Davoli MA, Nagy C, Zahedi RP, Borchers CH, Giros B, Turecki G, Mechawar N
Brain, behavior, and immunity 2024 Nov;122:110-121

Immortalization of mouse primary astrocytes.

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Gene 2023 May 20;865:147327

Autologous exosome facilitates load and target delivery of bioactive peptides to repair spinal cord injury.

Ran N, Li W, Zhang R, Lin C, Zhang J, Wei Z, Li Z, Yuan Z, Wang M, Fan B, Shen W, Li X, Zhou H, Yao X, Kong X, Feng S
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Primary Astrocytes Purification and Immortalization.

Qin L, Xiao G
Current protocols 2023 Dec;3(12):e964

Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.

Cui L, Zhao X, Jin Z, Wang H, Yang SF, Hu S
Journal of pineal research 2021 Dec;71(4):e12767

Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.

Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091

Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations.

Kano M, Takanashi M, Oyama G, Yoritaka A, Hatano T, Shiba-Fukushima K, Nagai M, Nishiyama K, Hasegawa K, Inoshita T, Ishikawa KI, Akamatsu W, Imai Y, Bolognin S, Schwamborn JC, Hattori N
NPJ Parkinson's disease 2020 Nov 13;6(1):33

Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines.

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Reversing a model of Parkinson's disease with in situ converted nigral neurons.

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Nature 2020 Jun;582(7813):550-556

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