11-13004-25

antibody from ABEOMICS Inc.
Targeting: PRKRA DYT16, HSD14, PACT, RAX
Provider product page for 11-13004-25

Antibody data

Product number
11-13004-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-RAX Antibody
Antibody type
Polyclonal
Description
RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant RAX pr
otein (amino acids 100-313) was use
d as the immunogen for this antibod
y.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
PRKRA protein structure - 11-13004-25 shown in red.